Abstract: A speaker can have a main body with a generally spheroidal shape, which can be supported standing on its end. The speaker can include a subwoofer that faces forward. A plurality of mid-range drivers can be distributed around the sub-woofer, facing generally forward and radially outward. A plurality of tweeters can be distributed around the sub-woofer, facing generally forward and generally outward. The outer housing portion of the speaker can be covered with a fabric material. A user interface ring 162 can be touch sensitive to receive input, and can have a plurality of lights that can be illuminated separately to convey information to the user.

Abstract: The present invention relates to a pharmaceutical composition of 8-chloro-5-methyl-1-[4-(2-pyridyloxy)cyclohexyl]-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, a process for the preparation thereof and its use in the treatment of diseases.

Abstract: The invention relates to PYY analogues having alanine at position 4, lysine at position 7, QRY as the C-terminal end and a half-life extending group. The analogues of the invention are soluble around pH 6 and 7. The invention also relates to pharmaceutical compositions comprising such PYY analogues, and to the medical use of the analogues.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: A method for converting an ultra low sulfur diesel fuel to a kerosene product includes receiving an ultra low sulfur diesel fuel within a reaction vessel, delivering a gas through one or more spargers positioned within a reaction vessel into the ultra low sulfur diesel fuel so as to form aerosol droplets, passing the aerosol droplets through one or more catalyst grids positioned within the reaction vessel at a level above the ultra low sulfur diesel fuel at a speed between 0.01 m/s and 0.7 m/s, collecting a product gas resulting from the passing of the aerosol droplets through the catalyst grids, and condensing the product gas to form a kerosene product.

Abstract: The invention relates to PYY analogues having alanine at position 4, lysine at position 7, QRY as the C-terminal end and a half-life extending group. The analogues of the invention are soluble around pH 6 and 7. The invention also relates to pharmaceutical compositions comprising such PYY analogues, and to the medical use of the analogues.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: A pet accessory comprising a leash and a receptacle for holding a spherical object is provided. The pet accessory provides a combination pet leash and sling for holding the spherical object which may also be used as a sling to hurl the object. The pet accessory comprising a leash, a sling system and a spherical object receptacle built into the pet accessory is capable of use to hurl a projectile easily without a separate accessory.

Abstract: The invention relates to PYY analogues having alanine at position 4, lysine at position 7, QRY as the C-terminal end and a half-life extending group. The analogues of the invention are soluble around pH 6 and 7. The invention also relates to pharmaceutical compositions comprising such PYY analogues, and to the medical use of the analogues.

Abstract: The present invention relates to a pharmaceutical composition of 8-chloro-5-methyl-1-[4-(2-pyridyloxy)cyclohexyl]-4,6-dihydro-[1,2,4]triazolo[4,3-a][1,4]benzodiazepine, a process for the preparation thereof and its use in the treatment of diseases.

Abstract: An EUV source for generating a beam of EUV radiation, has a droplet generator with a nozzle assembly to emit droplets of fuel from a nozzle towards a plasma formation location. The nozzle assembly receives the fuel from a reservoir. The nozzle assembly has a pump chamber receiving the fuel from the reservoir and an actuator to vibrate a membrane that forms a wall of the pump chamber. The wall is oriented perpendicularly to a direction wherein the nozzle emits the fuel. The nozzle assembly has first and second nozzle filters non-adjacently arranged in series in a path of the fuel from the pump chamber to the nozzle.

Abstract: In one example, a wearable device includes one or more processors, a plurality of communication components, one or more motion sensors configured to detect motion of the wearable device and generate, based on the detected motion, motion data, and a storage device configured to store at least one module. The at least one module may be operable by the one or more processors to: responsive to determining that the wearable device is not connected to the computing device using the first communication technology, determine, based on the motion data, whether the wearable device is currently being worn, and responsive to determining that the wearable device is currently being worn, establish the wireless connection to the computing device using the second communication component.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: Systems and techniques are described for providing guidance to an equivalence checker when a design contains retimed registers. Some embodiments can perform at least a register retiming optimization on a first design to obtain a second design. Next, the embodiments can determine one or more codes to provide guidance for connecting the set/clear inputs of the retimed registers. The first design, the second design, and the one or more codes can then be provided to an equivalence checker, wherein providing the one or more codes to the equivalence checker reduces an amount of computation required by the equivalence checker to determine functional equivalence between the first design and the second design.

Abstract: An apparatus for facilitating product exchanges includes a processor and memory storing executable computer code causing the apparatus to at least perform operations including triggering an exchange procedure to return a product(s) to an entity responsive to receipt of an indicated selection of a return service option. The computer program code may further cause the apparatus to generate a return label(s) and identify a box(es) for inclusion of the product responsive to the receipt of the indicated selection and may generate a notification(s) notifying a user of a pickup time for the product and receive an indication that the product is packaged in the box(es), that information of the return label is captured and that the product is collected for delivery. The computer program code may further cause the apparatus to receive an indication that the product is delivered to entity. Corresponding methods and computer program products are also provided.

Abstract: Systems and techniques are described for providing guidance to an equivalence checker when a design contains retimed registers. Some embodiments can perform at least a register retiming optimization on a first design to obtain a second design. Next, the embodiments can determine one or more codes to provide guidance for connecting the set/clear inputs of the retimed registers. The first design, the second design, and the one or more codes can then be provided to an equivalence checker, wherein providing the one or more codes to the equivalence checker reduces an amount of computation required by the equivalence checker to determine functional equivalence between the first design and the second design.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: This invention relates to 2-Aza-bicyclo[2.2.1]heptane-3-carboxylic acid (benzyl-cyano-methyl)-amides of formula 1 and their use as inhibitors of Cathepsin C, pharmaceutical compositions containing the same, and methods of using the same as agents for treatment and/or prevention of diseases connected with dipeptidyl peptidase I activity, e.g. respiratory diseases.

Abstract: An EUV source for generating a beam of EUV radiation, has a droplet generator with a nozzle assembly to emit droplets of fuel from a nozzle towards a plasma formation location. The nozzle assembly receives the fuel from a reservoir. The nozzle assembly has a pump chamber receiving the fuel from the reservoir and an actuator to vibrate a membrane that forms a wall of the pump chamber. The wall is oriented perpendicularly to a direction wherein the nozzle emits the fuel. The nozzle assembly has first and second nozzle filters non-adjacently arranged in series in a path of the fuel from the pump chamber to the nozzle.