Abstract: Provided herein is a disinfecting device including a container containing a chlorhexidine-based solution having a chlorhexidine concentration of from 0.2-2.0% wt/vol. Provided also is a medical connector disinfected with the disinfecting device. A method of disinfecting a medical connector using the disinfecting device is also disclosed.

Abstract: A nucleic acid loading device, including a housing, a carrying module, a motion module, a liquid circuit module and a control module. The motion module includes a support platform, first and second driving mechanisms, and a carrying member. The liquid circuit module is configured to control a reagent to flow into and out of a reactor. The control module is connected with the motion module and the liquid circuit module, and the control module is configured to control the first and second driving mechanisms, the liquid circuit module and the temperature control unit. A first face of a semiconductor cooler heats or refrigerates during operation, providing heat for an accommodating seat through a heat conducting body such that the reactor can be at different ambient temperatures. The cooperation between the motion and liquid circuit modules may achieve automation and industrialization of loading a sample into the reactor.

Abstract: A radar anti-spoofing system for an autonomous vehicle includes a plurality of radar sensors that generate a plurality of input detection points representing radio frequency (RF) signals reflected from objects and a controller in electronic communication with the plurality of radar sensors. The one or more controllers execute instructions to determine a signal to noise ratio (SNR) distance ratio for the input detection points generated by the plurality of radar sensors, where a value of the SNR distance ratio is indicative of an object being a ghost vehicle. The one or more controllers also determine an effective particle number indicating a degree of particle degradation for the importance sampling for each variable that is part of the state variable. In response to determining the effective particle number is equal to or less than a predetermined threshold, the one or more controllers estimate a ghost position for the ghost vehicle.

Abstract: A method, system, and computer program product for predicting abnormal operation of at least one component of a machine is provided. Real time monitoring data from an operating machine is received and monitoring features that are informative of likely abnormal operation are extracted and/or calculated. The monitoring features are applied to a prediction matrix that outputs probabilities of abnormal operation within one or more prediction time horizons. If the output probabilities exceed a threshold probability, then an alert can be output. Maintenance can be automatically scheduled in response to the alert.

Abstract: A radar anti-spoofing system for an autonomous vehicle includes a plurality of radar sensors that generate a plurality of input detection points representing radio frequency (RF) signals reflected from objects and a controller in electronic communication with the plurality of radar sensors. The one or more controllers execute instructions to determine a signal to noise ratio (SNR) distance ratio for the input detection points generated by the plurality of radar sensors, where a value of the SNR distance ratio is indicative of an object being a ghost vehicle. The one or more controllers also determine an effective particle number indicating a degree of particle degradation for the importance sampling for each variable that is part of the state variable. In response to determining the effective particle number is equal to or less than a predetermined threshold, the one or more controllers estimate a ghost position for the ghost vehicle.

Abstract: A radar anti-spoofing system for an autonomous vehicle includes a plurality of radar sensors that generate a plurality of input detection points representing radio frequency (RF) signals reflected from objects and a controller in electronic communication with the plurality of radar sensors. The controller executes instructions to determine time-matched clusters that represent objects located in an environment surrounding the autonomous vehicle based on the input detection points from the plurality of radar sensors. The controller determines an adjusted signal to noise (SNR) measure for a specific time-matched cluster by dividing an SNR of the specific time-matched cluster by a range measurement of the specific time-matched cluster. The controller determines a velocity-ratio measure of the time-matched cluster by dividing a motion-based velocity by a Doppler-frequency velocity, and identifies the time-matched cluster as either a ghost object or a real object.

Abstract: A computing system including a processor configured to train a synthetic aperture radar (SAR) classifier neural network. The SAR classifier neural network is trained at least in part by, at a SAR encoder, receiving training SAR range profiles that are tagged with respective first training labels, and, at an image encoder, receiving training two-dimensional images that are tagged with respective second training labels. Training the SAR classifier neural network further includes, at a shared encoder, computing shared latent representations based on the SAR encoder outputs and the image encoder outputs, and, at a classifier, computing respective classification labels based on the shared latent representations. Training the SAR classifier neural network further includes computing a value of a loss function based on the plurality of first training labels, the plurality of second training labels, and the plurality of classification labels and performing backpropagation based on the value of the loss function.

Abstract: This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with CNS disorders. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g., an ?5-containing GABAA receptor positive allosteric modulator) in treating cognitive impairment associated with CNS disorders in a subject in need or at risk thereof, including age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI, Age-Associated Memory Impairment, Age Related Cognitive Decline, dementia, Alzheimer's Disease (AD), prodromal AD, PTSD, schizophrenia, bipolar disorder, ALS, cancer-therapy-related cognitive impairment, mental retardation, Parkinson's disease, autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g.

Abstract: This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with CNS disorders. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g, an ?5-containing GABAA receptor positive allosteric modulator) in treating cognitive impairment associated with CNS disorders in a subject in need or at risk thereof, including age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI, Age-Associated Memory Impairment, Age Related Cognitive Decline, dementia, Alzheimer's Disease (AD), prodromal AD, PTSD, schizophrenia, bipolar disorder, ALS, cancer-therapy-related cognitive impairment, mental retardation, Parkinson's disease, autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g.

Abstract: This invention relates to benzodiazepine derivatives, compositions comprising therapeutically effective amounts of those derivatives and methods of using those derivatives or compositions in treating cognitive impairment associated with CNS disorders. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g., an ?5-containing GABAA receptor positive allosteric modulator) in treating cognitive impairment associated with CNS disorders in a subject in need or at risk thereof, including age-related cognitive impairment, Mild Cognitive Impairment (MCI), amnestic MCI, Age-Associated Memory Impairment, Age Related Cognitive Decline, dementia, Alzheimer's Disease (AD), prodromal AD, PTSD, schizophrenia, bipolar disorder, ALS, cancer-therapy-related cognitive impairment, mental retardation, Parkinson's disease, autism spectrum disorders, fragile X disorder, Rett syndrome, compulsive behavior, and substance addiction. It also relates to the use of an ?5-containing GABAA receptor agonist (e.g.

Abstract: Disclosed is a synthetic aperture radar (SAR) system for target recognition with complex range profile. The SAR system comprising a memory, a recurrent neural network (RNN), a multi-layer linear network in signal communication the RNN, and a machine-readable medium on the memory. The machine-readable medium is configured to store instructions that, when executed by the RNN, cause the SAR system to perform various operations. The various operation comprise: receiving raw SAR data associated with observed views of a scene, wherein the raw SAR data comprises information captured via the SAR system; radio frequency (RF) preprocessing the received raw SAR data to produce a processed raw SAR data; converting the processed raw SAR data to a complex SAR range profile data; processing the complex SAR range profile data with the RNN having RNN states; and mapping the RNN states to a target class with the multi-layer linear network.

Abstract: Described is a method for extraction of a region of interest (ROI) from a composite synthetic aperture radar (SAR) phase history data. The method comprising receiving, with a system comprising a processor, the composite SAR phase history data of a plurality of backscattered return signals produced by a SAR system illuminating a scene with a SAR beam. The method also comprises obtaining a location of a first ROI within the scene and extracting from the composite SAR phase history data a first component SAR phase history data corresponding to the ROI at the location of the ROI.

Abstract: A method is disclosed. The method models a plurality of visual cortex neurons, models one or more connections between at least two visual cortex neurons in the plurality of visual cortex neurons, assigns synaptic weight value to at least one of the one or more connections, simulates application of one or more electrical signals to at least one visual cortex neuron in the plurality of visual cortex neurons, adjusts the synaptic weight value assigned to at least one of the one or more connection based on the one or more electrical signals, and generates an orientation map of the plurality of visual cortex neurons based on the adjusted synaptic weight values.

Abstract: A method of identifying a target from synthetic aperture radar (SAR) data without incurring the computational load associated with generating an SAR image. The method includes receiving SAR data collected by a radar system including RF phase history data associated with reflected RF pulses from a target in a scene, but excluding an SAR image. Range profile data is determined from the SAR data by converting the RF phase history data into a structured temporal array that can be applied as input to a classifier incorporating a recurrent neural network, such as a recurrent neural network made up of long short-term memory (LSTM) cells that are configured to recognize temporal or spatial characteristics associated with a target, and provide an identification of a target based on the recognized temporal or spatial characteristic.

Abstract: Glucosylceramide synthase inhibitors and compositions containing the same are disclosed. Methods of using the glucosylceramide synthase inhibitors in the treatment of diseases and conditions wherein inhibition of glucosylceramide synthase provides a benefit, like Gaucher disease and Fabry disease, also are disclosed.

Abstract: Described is a system for online vehicle recognition in an autonomous driving environment. Using a learning network comprising an unsupervised learning component and a supervised learning component, images of moving vehicles extracted from videos captured in the autonomous driving environment are learned and classified. Vehicle feature data is extracted from input moving vehicle images. The extracted vehicle feature data is clustered into different vehicle classes using the unsupervised learning component. Vehicle class labels for the different vehicle classes are generated using the supervised learning component. Based on a vehicle class label for a moving vehicle in the autonomous driving environment, the system selects an action to be performed by the autonomous vehicle, and causes the selected action to be performed by the autonomous vehicle in the autonomous driving environment.

Abstract: Described is a system for predicting future social activity. The system extracts social activities from spatial-temporal social network data collected in a first time period ranging from hours to days to capture spatial structures of social activities in a graph network representation. A graph matching technique is applied over a set of spatial-temporal social network data collected in a second time period ranging from weeks to months to capture temporal structures of the social activities. A spatial-temporal structure of each social activity is represented as an activity core, where each activity core is defined as active nodes that participate in the social activity with a frequency over a predetermined threshold over the second time period. For each activity core, the system computes statistics of the social activity and uses the statistics to generate a prediction of future behaviors of the social activity.

Abstract: A system configured to identify a target in a synthetic aperture radar signal includes: a feature extractor configured to extract a plurality of features from the synthetic aperture radar signal; an input spiking neural network configured to encode the features as a first plurality of spiking signals; a multi-layer recurrent neural network configured to compute a second plurality of spiking signals based on the first plurality of spiking signals; a readout neural layer configured to compute a signal identifier based on the second plurality of spiking signals; and an output configured to output the signal identifier, the signal identifier identifying the target.