Abstract: Described herein is a method for enhancing image data that includes transforming image data from an intensity domain to a wavelet domain to produce wavelet coefficients. A first set of wavelet coefficients of the wavelet coefficients includes low-frequency wavelet coefficients. The method also includes modifying the first set of wavelet coefficients using a coefficient distribution based filter to produce a modified first set of wavelet coefficients. The method includes transforming the modified first set of wavelet coefficients from the wavelet domain to the intensity domain to produce enhanced image data.

Abstract: The present invention is directed to compounds that modulate the bioactivity of an orexin receptor such as OX1 or OX2, or both; to pharmaceutical compositions and combinations comprising a compound of the invention; to methods of treatment of malconditions in patients wherein modulation of an orexin receptor is medically indicated; and to methods of preparation of compounds of the invention.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: A method and system for video-content based retrieval is described. A query video depicting an activity is processed using interest point selection to find locations in the video that are relevant to that activity. A set of spatio-temporal descriptors such as self-similarity and 3-D SIFT are calculated within a local neighborhood of the set of interest points. An indexed video database containing videos similar to the query video is searched using the set of descriptors to obtain a set of candidate videos. The videos in the video database are indexed hierarchically using a vocabulary tree or other hierarchical indexing mechanism.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: A tone detector and associated method for use with EVRC-B and GSM vocoders to enable reliable detection of system connect tones over a wireless communication system. The tone detection method examines a number of sequential data frames of the signal received from the vocoder and determines that the tone is present if the spectral energy at frequencies around the tone is much higher than that at neighboring frequencies and if the calculated center frequency of the data frames is at or near the frequency of the tone.

Abstract: A method and apparatus for processing sound from a sound source. The sound from the sound source is detected. Harmonics in the sound from the sound source are identified. A distance to the sound source is identified using the harmonics and a number of atmospheric conditions.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: Disclosed herein are compounds, and pharmaceutical compositions that include such compounds, for preventing, treating, and/or protecting against sensory hair cell death. Methods of using the compounds, alone or in combination with other therapeutic agents, are also disclosed.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: The present invention relates generally to compositions and methods for treating neurodegenerative diseases and disorders, particularly ophthalmic diseases and disorders. Provided herein are styrenyl derivative compounds, including but not limited to stilbene derivative compounds, and compositions comprising these compounds, that are useful for treating and preventing ophthalmic diseases and disorders, including age-related macular degeneration (AMD) and Stargardt's Disease.

Abstract: Described is a system for automatic data clustering which utilizes bio-inspired computing models. The system performs operations of mapping a set of input data into a feature space using a bio-inspired computing model. A number of clusters inside the set of input data is then determined by finding an optimal vigilance parameter using a bio-inspired computing model. Finally, the set of input data is clustered based on the determined number of clusters. The input data is mapped with a Freeman's KIII network, such that each data point is mapped into a KIII network response. Furthermore, the number of clusters is determined using the fuzzy adaptive resonance theory (ART), and the data is clustered using the fuzzy c-means method. Clustering quality measures are used to compute an objective function to evaluate the quality of clustering.

Abstract: This application provides for compounds of the formula Formula I or a pharmaceutically acceptable salt thereof, wherein the individual variables are defined herein, as well as processes to prepare these compounds, pharmaceutical compositions comprising the same and their use in treating disease state associated with the CRTH2 receptor.

Abstract: Described is a system for content recognition, search, and retrieval in visual data. The system is configured to perform operations of receiving visual data as an input, processing the visual data, and extracting distinct activity-agnostic content descriptors from the visual data at each level of a hierarchical content descriptor module. The resulting content descriptors are then indexed with a hierarchical content indexing module, wherein each level of the content indexing module comprises a distinct set of indexed content descriptors. The visual data, generated content descriptors, and indexed content descriptors are then stored in a storage module. Finally, based on a content-based query by a user, the storage module is searched, and visual data containing the content of interest is retrieved and presented to the user. A method and computer program product for content recognition, search, and retrieval in visual data are also described.

Abstract: In certain embodiments, a method for compressing n-dimensional data includes applying a data clustering algorithm to n-dimensional data to partition the n-dimensional data into one or more clusters. Each of the one or more clusters includes a cluster center and a cluster membership. The cluster membership includes an index of one or more cluster members of the cluster. The method further includes performing, for each of the one or more clusters, a subspace projection technique to generate, for each of the cluster members of the cluster, one or more projection coefficients for the cluster member.

Abstract: A system, method, and apparatus for radar pulse detection using a digital radar receiver are disclosed herein. In electronic warfare (EW), radars operate in an environment with highly dense electronic waveforms. As a result, the radars may receive thousands or millions of radar pulses every second. To detect and sort out radar pulses emitted from different radars is a challenging problem in electronic warfare. The present disclosure teaches a radar pulse detection system that utilizes digital channelization and joint-channel detection techniques to detect and separate radar pulses that are sent from different radar emitters. The main features of the present disclosure are: 1.) a digital channelization technique to separate radar pulses from their mixtures; 2.) a multi-channel detection technique to detect radar pulses; and 3.) an innovative technique to separate overlapped radar pulses.

Abstract: A method and apparatus for processing sound from a sound source. The sound from the sound source is detected. Harmonics in the sound from the sound source are identified. A distance to the sound source is identified using the harmonics and a number of atmospheric conditions.

Abstract: The invention provides certain quinoxalines and aza-quinoxalines of the Formula (I), and their pharmaceutically acceptable salts, wherein J1, J2, R1, R2, R3, R22, Ra, Rb, Rc, Rd, X, Y, b, n, and q are as defined herein. The invention also provides pharmaceutical compositions comprising such compounds, and methods of using the compounds for treating diseases or conditions associated with uncontrolled or inappropriate stimulation of CRTH2 function.