Abstract: A pharmaceutical delivery device includes a cartridge containing a fluid. The cartridge includes a light pipe section having an input location and a light diffusing section optically coupled to the light pipe. A light source is optically coupled to the cartridge at the input location to the light pipe, such that at least some light from the light source entering at the input location is diffused at the light diffusing section.

Abstract: A method of manufacturing an autoinjector includes supplying a preloaded syringe including a sterile needle and a needle cover, a preassembled distal housing portion including an adhesive base on a distal end thereof and a channel for insertion of the preloaded syringe, and a proximal housing portion including a motor and a transmission. An activation device is supplied and the preloaded syringe is slid longitudinally through an opening in a proximal end of the distal housing portion into the channel. A distal end of the proximal housing portion is joined to a proximal end of the distal housing portion.

Abstract: An injector includes an injector housing defining a skin contact surface and an injection needle supported within the housing and movable from a retracted position to an injection position. A circuit board is supported within the housing and movable with the injection needle, the circuit board including an electrically disconnected circuit having a contact surface. An electromechanical sensor is also supported within the housing and movable with the injection needle.

Abstract: Embodiments are disclosed of a method of controlling timing and/or dosage of a transdermal drug patch. For example, a control device operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being fully engaged with the skin, partially engaged with the skin, and disengaged with the skin. The device may include a roller that peels a patch on and off the skin. Optionally a convention patch is used. In some embodiments a patch and/or an adaptor has a mobile zone and an immobile zone. In some embodiments, an active surface of the patch fully contacts the skin in an engaged state. For example the patch may be attached to the device on a passive portion thereof.

Abstract: An injector including at least one fluid reservoir having a needle, a surface attached to skin and coupled to the fluid reservoir by at least a first joint and a second joint at least a portion of one of the joints being slidable or having interlocking arms. At least a portion of a path of translation of a slidable portion of the first joint and a portion of a path of translation of the second joint are angled in respect to each another.

Abstract: An add-on for a self-injector including an adaptor and a bent fluid path is provided. The adaptor includes at least one coupling sized and shaped to couple the adaptor to a fluid reservoir. The bent fluid path is configured at a first end to penetrate tissue and coupled at a second end to the adaptor. The add-on coupled to the fluid reservoir forms an integral self-injector cartridge unit configured to be sterilized and filled with an injectable. The adaptor is configured to couple to a self-injector at least one of a plurality of reservoirs having different sizes and tip types.

Abstract: An autoinjector including a syringe, a driver for driving the plunger of the syringe and a stabilizing adaptor for holding the injector on the skin of a patient is provided. The stabilizing adaptor has an adhesive base with a long axis to short axis ratio of at least 1.5 to 1. The syringe is orientated with its axis at an angle of between 60 and 120 degrees to the base during operation of the autoinjector.

Abstract: A wearable medical device may be unpacked, prepared, and/or used while being grasped with a single hand position. For example, the device may be removed from a package, primed, and/or adhered to the skin of a user while being grasped with the single hand position. Optionally, the device may be used with a single hand. Optionally, the device includes a delivery interface (for example, including a needle tip and/or a skin contact surface). Optionally, the device includes a protector that preserves sterility of the delivery interface. Optionally, the cover can be removed with a single hand. Optionally, removal of the cover is performed with the same hand position as placement of the device on a delivery site.

Abstract: Embodiments are disclosed of a method of controlling timing and/or dosage of a transdermal drug patch. For example, a control device operative to move the patch to one or more of a plurality of operational relationships with a skin of a patient, including being fully engaged with the skin, partially engaged with the skin, and disengaged with the skin. The device may include a roller that peels a patch on and off the skin. Optionally a convention patch is used. In some embodiments a patch and/or an adaptor has a mobile zone and an immobile zone. In some embodiments, an active surface of the patch fully contacts the skin in an engaged state. For example the patch may be attached to the device on a passive portion thereof.

Abstract: An add-on for a self-injector including an adaptor and a bent fluid path is provided. The adaptor includes at least one coupling sized and shaped to couple the adaptor to a fluid reservoir. The bent fluid path is configured at a first end to penetrate tissue and coupled at a second end to the adaptor. The add-on coupled to the fluid reservoir forms an integral self-injector cartridge unit configured to be sterilized and filled with an injectable. The adaptor is configured to couple to a self-injector at least one of a plurality of reservoirs having different sizes and tip types.

Abstract: A wearable medical device may be unpacked, prepared, and/or used while being grasped with a single hand position. For example, the device may be removed from a package, primed, and/or adhered to the skin of a user while being grasped with the single hand position. Optionally, the device may be used with a single hand. Optionally, the device includes a delivery interface (for example, including a needle tip and/or a skin contact surface). Optionally, the device includes a protector that preserves sterility of the delivery interface. Optionally, the cover can be removed with a single hand. Optionally, removal of the cover is performed with the same hand position as placement of the device on a delivery site.

Abstract: An injector including at least one fluid reservoir having a needle, a surface attached to skin and coupled to the fluid reservoir by at least a first joint and a second joint at least a portion of one of the joints being slidable or having interlocking arms. At least a portion of a path of translation of a slidable portion of the first joint and a portion of a path of translation of the second joint are angled in respect to each another.

Abstract: An assembly for advancing a piston through a rotationally fixed cartridge includes a rotatable, axially fixed first member and an axially movable, rotatable second member connected thereto via a threaded connection and connectable to the piston. A friction pad is rotationally fixedly connected with the second member and includes first and second sets of fingers extending radially outwardly from a central disk. Both the first and second sets of fingers are configured to contact an interior side wall of the cartridge. The first set of fingers are angled toward a first rotational direction and are configured to wedge the friction pad between the side wall and the second member upon rotation of the first member in the first direction, thereby substantially preventing rotation in the first direction. The second set of fingers are angled toward a second rotational direction and are configured to substantially prevent rotation in the second direction.

Abstract: An extender for filling a syringe cartridge at a filling station having an elevating bar has a connector portion connecting a proximal portion of the extender to a distal portion of the syringe cartridge. A head on a distal portion of the extender is sized and shaped to engage the elevating bar of the filling station. The syringe cartridge having the extender may be provided to a filling station that is configured for filling a long syringe cartridge having a long syringe-cartridge length greater than a length of the syringe cartridge. The syringe cartridge and extender may be supported on a syringe support of the filling station and passed through the filling station to fill the syringe cartridge.

Abstract: A drug delivery device is disclosed that includes a housing including a channel, a drug reservoir fitting into the channel, and a friction element extending from a housing to the channel to contact an exterior side wall of the reservoir when the reservoir is inserted into the channel. The friction element is configured and oriented to wedge between the exterior wall and the reservoir when the reservoir is rotated in a first rotational direction.

Abstract: An assembly for advancing a piston through a rotationally fixed cartridge includes a rotatable, axially fixed first member and an axially movable, rotatable second member connected thereto via a threaded connection and connectable to the piston. A friction pad is rotationally fixedly connected with the second member and includes first and second sets of fingers extending radially outwardly from a central disk. Both the first and second sets of fingers are configured to contact an interior side wall of the cartridge. The first set of fingers are angled toward a first rotational direction and are configured to wedge the friction pad between the side wall and the second member upon rotation of the first member in the first direction, thereby substantially preventing rotation in the first direction. The second set of fingers are angled toward a second rotational direction and are configured to substantially prevent rotation in the second direction.