Abstract: A patch injector (10) for parenteral administration of a drug to a drug recipient has a drug-cartridge module (14) attached to a power-pack module (12) and to a drug-recipient interface module (16). A compressed, elastic power element (18) disposed in the power-pack module (12) is coupled to a plunger (30) movably disposed in a drug reservoir (22) in the drug-cartridge module (14). An injection needle (24) at the distal end of the drug reservoir (22) is oriented orthogonal to the drug reservoir (22) and generally toward a skin-contact surface (28) extending parallel to the longitudinal drug-reservoir axis (22A). The power element (18) is configured to displace the plunger (20) distally into the drug reservoir (22) and to move the injection needle (24) toward the skin-contact surface (28) when the power element (18) expands distally along the drug-reservoir axis (22A).

Abstract: A device for drug injection has a cartridge, which in turn has a reservoir and a fluid path. The fluid path carries a fluid for injection from the reservoir to the place where the patient is to be injected. The fluid path comprises a needle, and the fluid path is kept sterile. A drive chain extends the needle to the injection point, but is only mechanically connected to the fluid path to operate the needle, the mechanical connection being such as to operate the needle while maintaining the fluid path sterility.

Abstract: A securing device for an injection device which receives a syringe with a proximal end portion having a radially outwardly projecting flange, has a body with proximal and distal end portions, an opening for accepting the syringe, an outer surface, and a proximal end surface for contacting a distally-facing surface of the flange when the syringe is advanced distally, preventing further advancement. A securing arm includes a free end; a base end fixed to the outer surface; a first portion extending radially outwardly from the base end to permit the flange to pass; and a second portion extending radially inwardly in a rest position, contacting the flange as the syringe is advanced. The securing arm is elastically flexible to allow the free end to move radially outwardly, allowing the advancing flange to pass, and is biased to the rest position to secure the flange and the syringe against proximal movement.

Abstract: A patch injector (10) for parenteral administration of a drug to a drug recipient has a drug-cartridge module (14) attached to a power-pack module (12) and to a drug-recipient interface module (16). A compressed, elastic power element (18) disposed in the power-pack module (12) is coupled to a plunger (30) movably disposed in a drug reservoir (22) in the drug-cartridge module (14). An injection needle (24) at the distal end of the drug reservoir (22) is oriented orthogonal to the drug reservoir (22) and generally toward a skin-contact surface (28) extending parallel to the longitudinal drug-reservoir axis (22A). The power element (18) is configured to displace the plunger (20) distally into the drug reservoir (22) and to move the injection needle (24) toward the skin-contact surface (28) when the power element (18) expands distally along the drug-reservoir axis (22A).

Abstract: An injector includes a needle movable from a retracted position to an injection position. A rotary biasing assembly is stabilized in a stored energy state and releasable into an energy releasing state and includes a cam. A cam follower couples the rotary biasing assembly with the needle and is configured to transform rotation of the rotary biasing assembly in the energy releasing state thereof into translation of the needle from the retracted position to the injection position. An activation switch is rotatable from an unactivated position, stabilizing the rotary biasing assembly in the stored energy state thereof, to an activated position, releasing the rotary biasing assembly into the energy releasing state thereof. An activation button is movably mounted to the injector housing and is translatable from an unactuated position to an actuated position, whereby the translation rotates the activation switch from the unactivated position to the activated position thereof.

Abstract: A system and method are provided for preventing a sharp stick hazard from a needle tip of an automatic injector device. In some embodiments, a skin contact surface of the device is attached to an injection site, for example by an adhesive. Optionally a locking mechanism holds a needle extended into an injection site. A body of the device is optionally movably attached to the skin contact surface. Pulling the body away from the injection site optionally moves the body with respect to the skin contact surface. Movement of the body with respect to the skin contact surface optionally moves interlinked parts of the locking mechanism, releasing the locking mechanism.

Abstract: A cartridge comprising a reservoir part and an extension extending from said reservoir part, said extension defining a fluid path and comprising a molding and a first needle extending from said molding, the extension turning to a finite angle with respect to an axis of said reservoir part and wherein at least part of said first needle is likewise at said finite angle, at least some of said part of said first needle at said finite angle being enclosed within said molding of said fluid path. A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

Abstract: A system and method are provided for preventing a sharp stick hazard from a needle tip of an automatic injector device. In some embodiments, a skin contact surface of the device is attached to an injection site, for example by an adhesive. Optionally a locking mechanism holds a needle extended into an injection site. A body of the device is optionally movably attached to the skin contact surface. Pulling the body away from the injection site optionally moves the body with respect to the skin contact surface. Movement of the body with respect to the skin contact surface optionally moves interlinked parts of the locking mechanism, releasing the locking mechanism.

Abstract: A syringe cartridge comprising a reservoir part and an extension extending from said reservoir part, said extension defining a fluid path and comprising a molding and a first needle extending from said molding, the extension turning to a finite angle with respect to an axis of said reservoir part and wherein at least part of said first needle is likewise at said finite angle, at least some of said part of said first needle at said finite angle being enclosed within said molding of said fluid path. A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

Abstract: A method is disclosed for state sensing and controlling of a multi-state drug delivery device. In some embodiments a power switch is reused as a state sensor. Optionally the state sensor may be toggled by user actions and/or the movements of parts of the device, for example needle and/or a protective element. Optionally, drug discharge and/or status indication is controlled in accordance with sensor output. In some embodiments control is by means of a processor. Alternatively or additionally, control is by means of simple physical circuits.

Abstract: An automatic injector for delivering a pharmaceutical substance from a reservoir of a cartridge, the cartridge interconnected to a needle at its distal end and mechanically coupled to a plunger driver at its proximal end, the injector comprising a connecting feature on the cartridge a contact surface for contacting an injection site a frame connected to the contact surface, the frame having an interference element with a distal stop, the interference element sized to slidably link to the connecting feature and allow the cartridge to slide up to the distal stop, a snap element allowing the interference element to receive the connection feature, but inhibiting disconnection of the cartridge; the frame further comprising a driver mount, for fixedly containing a plunger driver, the driver for driving a plunger to empty the reservoir of the cartridge through the needle to inject fluid from the reservoir into the injection subject.

Abstract: A needle insertion and retraction mechanism for a drug delivery device, comprises a motion source, a user-operated control for the motion source, an interrupter for stopping motion of the motion source at a predetermined location and thereby dividing the motion into two parts which are continuous relative to each other. A motion translation mechanism connects the source of continuous motion to a needle, to extend the needle during the first motion part and to retract the needle during the second motion part. The needle is thus extended and retracted by continued operation of a single tension source rather than two tension sources operating in opposition to each other. The motion source may be a spring, and a winding mechanism may be provided to wind the spring. The second motion part may be initiated by pulling the adhered delivery device from the skin.

Abstract: A drug delivery device may include sterile needle covered by removable a sterility preserving protector. The device optionally includes skin contact surface and a needle protector for preventing a stick hazard upon removal of the skin contact surface from an injection site or angle without Removing completely. Optionally, the needle protector may include a shield that interferes with replacement of the needle protector. In some embodiments, the needle cover may interfere with deployment of the needle protector.

Abstract: A syringe cartridge comprising a reservoir part and an extension extending from said reservoir part, said extension defining a fluid path and comprising a molding and a first needle extending from said molding, the extension turning to a finite angle with respect to an axis of said reservoir part and wherein at least part of said first needle is likewise at said finite angle, at least some of said part of said first needle at said finite angle being enclosed within said molding of said fluid path. A drug delivery device may be used with the cartridge and includes a skin-contacting surface. In use the longitudinal axis of the interior of the cartridge may be disposed substantially parallel to the skin-contacting surface.

Abstract: An automatic injector for delivering a pharmaceutical substance from a reservoir of a cartridge, the cartridge interconnected to a needle at its distal end and mechanically coupled to a plunger driver at its proximal end, the injector comprising a connecting feature on the cartridge a contact surface for contacting an injection site a frame connected to the contact surface, the frame having an interference element with a distal stop, the interference element sized to slidably link to the connecting feature and allow the cartridge to slide up to the distal stop, a snap element allowing the interference element to receive the connection feature, but inhibiting disconnection of the cartridge; the frame further comprising a driver mount, for fixedly containing a plunger driver, the driver for driving a plunger to empty the reservoir of the cartridge through the needle to inject fluid from the reservoir into the injection subject.

Abstract: A wearable medical device may be unpacked, prepared, and/or used while being grasped with a single hand position. For example, the device may be removed from a package, primed, and/or adhered to the skin of a user while being grasped with the single hand position. Optionally, the device may be used with a single hand. Optionally, the device includes a delivery interface (for example, including a needle tip and/or a skin contact surface). Optionally, the device includes a protector that preserves sterility of the delivery interface. Optionally, the cover can be removed with a single hand. Optionally, removal of the cover is performed with the same hand position as placement of the device on a delivery site.

Abstract: An injector including at least one fluid reservoir having a needle, a surface attached to skin and coupled to the fluid reservoir by at least a first joint and a second joint at least a portion of one of the joints being slidable or having interlocking arms. At least a portion of a path of translation of a slidable portion of the first joint and a portion of a path of translation of the second joint are angled in respect to each another.

Abstract: An injector including at least one fluid reservoir having a needle, a surface attached to skin and coupled to the fluid reservoir by at least a first joint and a second joint at least a portion of one of the joints being slidable or having interlocking arms. At least a portion of a path of translation of a slidable portion of the first joint and a portion of a path of translation of the second joint are angled in respect to each another.

Abstract: A needle insertion and retraction mechanism for a drug delivery device, comprises a motion source, a user-operated control for the motion source, an interrupter for stopping motion of the motion source at a predetermined location and thereby dividing the motion into two parts which are continuous relative to each other. A motion translation mechanism connects the source of continuous motion to a needle, to extend the needle during the first motion part and to retract the needle during the second motion part. The needle is thus extended and retracted by continued operation of a single tension source rather than two tension sources operating in opposition to each other. The motion source may be a spring, and a winding mechanism may be provided to wind the spring. The second motion part may be initiated by pulling the adhered delivery device from the skin.