Abstract: Disclosed is an alternative fuel fueling station useful for fueling both electrical and hydrogen alternative fuel vehicles simultaneously. The alternative fuel fueling station includes a solid oxide fuel cell, an electrical conduit, and a compressed hydrogen conduit, such that the alternative fuel fueling station can fuel both the electrical and hydrogen alternative fuel vehicles simultaneously.

Abstract: The present invention provides methods, compositions, and systems for distributing molecules and complexes into reaction sites. In particular, the methods, compositions, and systems of the present invention result in an active loading of molecules and complexes into reaction sites with improved efficiency over loading by passive diffusion methods alone.

Abstract: An equalizer and method is implemented to improve the performance of a communication system based on multi-level amplitude modulation schemes. The equalizer may include a linear equalization circuit including a plurality of time delayed taps and configured to receive an input signal and generate an output signal. The equalizer may further include a nonlinear circuit configured to receive signals from at least a portion of the time delayed taps and generate at least a portion of a difference between the signals, the output signal based at least in part on the difference.

Abstract: A SOFC system for producing a refined carbon dioxide product, electrical power, and a compressed hydrogen product is presented. The system can include a hydrodesulfurization system, a steam reformer, a water-gas shift reactor system, a hydrogen purification system, a hydrogen compression and storage system, a pre-reformer, and a CO2 purification and liquidification system.

Abstract: A method for producing a purified carbon dioxide product suitable for EOR and surplus electricity uses a vaporous hydrocarbon feed and a SOFC system. A SOFC system includes a condensate removal system, an acid gas removal system, a hydrodesulfurization system, a sorption bed system, a pre-reformer, a solid oxide fuel cell, a CO2 separations system and a CO2 dehydration system operable to form the purified carbon dioxide product, where the SOFC system is operable to produce surplus electricity from the electricity produced by the solid oxide fuel cell. A method of operating the pre-reformer to maximize the internal reforming capacity of a downstream solid oxide fuel cell uses a pre-reformer fluidly coupled on the upstream side of a solid oxide fuel cell. A method of enhancing hydrocarbon fluid recovery from a hydrocarbon-bearing formation using a SOFC system.

Abstract: This disclosure provides systems, methods, and apparatus related to boron nitride nanomaterials. In one aspect, a method includes generating a directed flow of plasma. A boron-containing species is introduced to the directed flow of the plasma. Boron nitride nanostructures are formed in a chamber. In another aspect, a method includes generating a directed flow of plasma using nitrogen gas. A boron-containing species is introduced to the directed flow of the plasma. The boron-containing species can consist of boron powder, boron nitride powder, and/or boron oxide powder. Boron nitride nanostructures are formed in a chamber, with a pressure in the chamber being about 3 atmospheres or greater.

Abstract: The invention provides a method for screening for colorectal cancer, the method comprising: screening a biological sample from an individual for one or more biomarkers selected from the group defined in Table 1 and/or Table 6, wherein the presence of or increased expression of the one or more biomarkers relative to a control sample is indicative that the individual is at risk of suffering from or is suffering from colorectal cancer. The invention also provides an array and kit suitable for use in the methods of the invention, methods of treating colorectal cancer and therapeutic agents for use in methods of treating cancer.

Abstract: Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.

Abstract: A method for producing a purified carbon dioxide product suitable for EOR and surplus electricity uses a vaporous hydrocarbon feed and a SOFC system. A SOFC system includes a condensate removal system, an acid gas removal system, a hydrodesulfurization system, a sorption bed system, a pre-reformer, a solid oxide fuel cell, a CO2 separations system and a CO2 dehydration system operable to form the purified carbon dioxide product, where the SOFC system is operable to produce surplus electricity from the electricity produced by the solid oxide fuel cell. A method of operating the pre-reformer to maximize the internal reforming capacity of a downstream solid oxide fuel cell uses a pre-reformer fluidly coupled on the upstream side of a solid oxide fuel cell. A method of enhancing hydrocarbon fluid recovery from a hydrocarbon-bearing formation using a SOFC system.

Abstract: Compositions, methods and systems are provided for isolating DNA having a modified or unnatural base. Circular DNA fragments, each comprising a double stranded DNA central region and single stranded regions on the ends of the double stranded regions, are obtained. Some of the fragments have one or more modified or unnatural base. The DNA fragments are treated with a primer and a polymerase such that the polymerase extends the primer to copy at least one of the strand of the double stranded region. This results in rendering the other strand single stranded. A binding protein or antibody that is specific to the modified or unnatural base is then used to isolate strands containing the modified or unnatural bases. Methods for loading such complexes onto substrates and for single molecule sequencing of such complexes are also provided.

Abstract: Compositions that include polymerases with features for improving entry of nucleotide analogues into active site regions and for coordinating with the nucleotide analogues in the active site region are provided. Methods of making the polymerases and of using the polymerases in sequencing and DNA replication and amplification as well as kinetic models of polymerase activity and computer-implemented methods of using the models are also provided.

Abstract: A wireless transmission control capability may be used to control downlink (DL) transmissions for a set of wireless user devices or for an individual wireless user device. A DL transmission control capability for a set of wireless user devices may include receiving DL channel operating parameter information associated with a set of cells, determining DL channel operating parameter distribution information based on the DL channel operating parameter information, and determining default DL channel operating parameter information for the set of cells based on the DL channel operating parameter distribution information and a target associated with the set of cells. A DL transmission control capability for an individual wireless user device may include determining radio link layer (RLL) retransmission information associated with a wireless user device and determining, based on the RLL retransmission information associated with the wireless user device, whether to modify an attribute of the wireless user device.

Abstract: The present invention provides methods, compositions, and systems for distributing single polymerase molecules into array regions. In particular, the methods, compositions, and systems of the present invention result in a distribution of single polymerase molecules into array regions at a percentage that is larger than the percentage expected to be occupied under a Poisson distribution.

Abstract: A wireless transmission control capability may be used to control downlink (DL) transmissions for a set of wireless user devices or for an individual wireless user device. A DL transmission control capability for a set of wireless user devices may include receiving DL channel operating parameter information associated with a set of cells, determining DL channel operating parameter distribution information based on the DL channel operating parameter information, and determining default DL channel operating parameter information for the set of cells based on the DL channel operating parameter distribution information and a target associated with the set of cells. A DL transmission control capability for an individual wireless user device may include determining radio link layer (RLL) retransmission information associated with a wireless user device and determining, based on the RLL retransmission information associated with the wireless user device, whether to modify an attribute of the wireless user device.

Abstract: Compositions, methods and systems are provided for the isolation of polymerase-nucleic acid complexes. Complexes can be separated from free enzyme by using hook molecules to target single stranded regions on the nucleic acid. Hook oligonucleotides are used to capture polymerase nucleic acid complexes where the nucleic acids comprise circular nucleic acids having a double stranded central region with hairpin regions on each end. Methods for loading such complexes onto substrates and for single molecule sequencing of such complexes are also provided.

Abstract: The disclosed methods and systems include determining whether data packets are received within a desired time interval and/or transmitted within the desired time interval, the desired time interval is a desired amount of time between a reception of a first data packet and a reception of a second data packet; transmitting a first signal to a user equipment (UE) when each data packet is received within the desired time interval and/or transmitted within the desired time interval, the first signal instructing the UE to enter a delay-sensitive state such that the UE communicates data packets over a first channel; and transmitting a second signal to the UE when each data packet is not received within the desired time interval and/or not transmitted within the desired time interval, the second signal instructing the UE to enter a non-delay-sensitive state such that the UE communicates data packets over a second channel.

Abstract: A SOFC system for producing a refined carbon dioxide product, electrical power, and a compressed hydrogen product is presented. The system can include a hydrodesulfurization system, a steam reformer, a water-gas shift reactor system, a hydrogen purification system, a hydrogen compression and storage system, a pre-reformer, and a CO2 purification and liquidification system.

Abstract: Disclosed are compositions, devices, and methods for loading molecules of interest onto a substrate by contacting beads having molecules of interest attached to them with the substrate, for example by providing a field that brings the beads into proximity or contact with the substrate and moves the beads with respect to the substrate. Such molecules of interest can be deposited onto substrates for single-molecule analysis.

Abstract: A SOFC system for producing a refined carbon dioxide product, electrical power and a compressed hydrogen product is presented. Introducing a hydrocarbon fuel and steam to the SOFC system, operating the SOFC system such that the steam-to-carbon molar ratio in the pre-reformer is in a range of from about 3:1 to about 4:1, the oxygen in the reformer combustion chamber is in excess, greater than 90% of the carbon dioxide produced during the process forms the refined carbon dioxide product are steps in the process. An alternative fueling station having a SOFC system is useful for fueling both electrical and hydrogen alternative fuel vehicles. Introducing steam and a hydrocarbon fuel, operating the alternative fueling station, coupling the alternative fuel vehicle to the alternative fueling station, introducing an amount of alternative fuel and decoupling the alternative fuel vehicle are steps in the method of use.

Abstract: Methods for amplifying a desired target region of a nucleic acid through rolling circle amplification with a strand-displacing polymerase are provided. Concatameric hairpin products are resolved with endonuclease digestion, and the resulting amplified product hairpins or fragments can be circularized and employed as templates in a subsequent round of amplification. The methods are effective for targeted amplification of even highly repetitive sequences. Compositions, kits, and systems related to or useful in the methods are also described.