Abstract: Disclosed herein are functionalized oxazine dye compounds, compositions comprising the compounds, and methods of using the compounds, e.g., in nucleic acid amplification reactions. Also disclosed herein are labeled oligonucleotides and labeled nucleotide triphosphate compounds.

Abstract: An angle valve structure includes an angle valve body. The angle valve body is provided with a water inlet channel, a water outlet channel and an accommodation cavity. The accommodation cavity is rotationally provided with a valve core. One end of the valve core exposed outside the accommodation cavity is fixedly connected with a knob. The valve core is provided with a sealing block for sealing the water outlet channel when sealing. The valve core includes a main body part and an elastic arm whose one end is connected with the main body part. One side of the main body part is provided with a mounting slot for placing the sealing block, one side of the elastic arm is provided with an extrusion portion, and the other side of the elastic arm is provided with a contact portion against the sealing block after assembly.

Abstract: Described are coelenterazine analogues, methods for making the analogues, kits comprising the analogues, and methods of using the compounds for the detection of luminescence in luciferase-based assays.

Abstract: An angle valve structure includes an angle valve body. The angle valve body is provided with a water inlet channel, a water outlet channel and an accommodation cavity. The accommodation cavity is rotationally provided with a valve core. One end of the valve core exposed outside the accommodation cavity is fixedly connected with a knob. The valve core is provided with a sealing block for sealing the water outlet channel when sealing. The valve core includes a main body part and an elastic arm whose one end is connected with the main body part. One side of the main body part is provided with a mounting slot for placing the sealing block, one side of the elastic arm is provided with an extrusion portion, and the other side of the elastic arm is provided with a contact portion against the sealing block after assembly.

Abstract: Compounds that may inhibit Oplophorus-derived luciferases are disclosed as well as compositions and kits comprising the compounds and methods of using the compounds.

Abstract: Provided herein are methods, reagents, and kits for the isolation of sperm cells from other cell types and the purification of sperm-associated DNA from a complex sample. In particular, methods, reagents, and kits are provided for the separation of intact sperm cells from epithelial cells via binding of sperm cells to a cation exchange resin, and the extraction of sperm-associated DNA therefrom.

Abstract: A mounting bracket includes a bracket body, a locking assembly and support foot. The bracket body is configured for component installation. The locking assembly is arranged on the bracket body, and the support foot is arranged on the bracket body. The support foot is slide along the up and down direction of the bracket body, and the locking assembly is configured to lock the support foot at a preset position. Through the above structure, the support foot is installed on the ground and used to support the bracket body, and the locking assembly locks the support foot at a preset position to correspondingly adjust the height of the bracket body from the ground, so as to adjust the suspension height of the components installed on the bracket body.

Abstract: Disclosed herein are compounds that can be used to selectively detect nitric oxide in samples. Also disclosed herein are compositions comprising the compounds and methods of detecting nitric oxide using the compounds.

Abstract: Disclosed herein are compounds that can be used to selectively detect superoxide in samples. Also disclosed herein are compositions comprising the compounds and methods of detecting superoxide using the compounds.

Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.

Abstract: An adjustable height square outer cover with a built-in cylinder includes a water tank shell and a square outer cover, the water tank shell is provided with an installation accommodation cavity for containing the square outer cover, the water tank shell is also provided with support rack teeth, a locking release device is arranged in the square outer cover, and the locking release device is provided with locking release rack teeth matched with the support rack teeth. A first mounting cavity is arranged in the square outer cover, a support which can be adjusted horizontally is movably arranged in the first mounting cavity, a cylinder which can be adjusted longitudinally is movably arranged on the support, a pressing button is arranged on the cylinder, and the square outer cover is also clamped with a decorative cover for covering the first mounting cavity.

Abstract: A regulating device for regulating water consumption of a concealed water tank includes a water tank, a hinged base is fixedly arranged on the inner wall of the water tank, a water separator is hinged on the hinged base. A regulating mechanism is arranged between the hinged base and the water separator, and the regulating mechanism can drive the water separator to rotate and fix to divide the accommodation space of the water tank. Compared with the prior art, the regulating device realizes the variable volume of the water tank by regulating the rotation of the water separator through the regulating mechanism. The structure is simple and convenient for the later repair and maintenance of the water tank.

Abstract: A fastening assembly includes a mounting cylinder frame, a movable part and a turnover part, the mounting cylinder frame is provided with a first vertical beam and a transmission rod, the mounting cylinder is provided with a butting block at the top of the first vertical beam, the transmission rod passes through the butting block, the side wall of the first vertical beam is provided with a bulge, the movable part is connected with the transmission rod, and the turnover part is arranged on the first vertical beam and rotationally connected with the movable part. The turnover part is butted with the bulge, the turnover part is located between the butting block and the movable part, and has a vertical state and a horizontal state. The transmission rod is used to drive the turnover part to switch between the horizontal state or the vertical state.

Abstract: Provided herein are reagents and methods for incorporating modified nucleotides into DNA and detecting DNA synthesis. In particular, haloalkyl-modified nucleobases are provided for incorporation into nucleic acids for detection by bioluminescent binding agents.

Abstract: The present disclosure includes compositions and methods for improved DNA amplification reactions. In particular, the present disclosure provides compositions and methods for hot-start PCR applications using DNA polymerase inhibitors that minimize non-specific DNA amplification by inactivating DNA polymerase at lower temperatures.

Abstract: A threaded fastening assembly includes a nut body and a screw body. The internal thread of the nut body includes a nut thread crest and a nut thread root. The external thread of the screw body includes a screw thread crest, a screw thread root, a fourth side wall located on one side of the screw thread crest, and a fifth side wall located on the other side of the screw thread crest. A locking notch located on one side of the nut thread crest is arranged on the internal thread. The locking notch includes a first side wall and a bottom wall. One end of the first side wall is connected to the nut thread crest, and the other end of the first side wall is connected to one end of the bottom wall. The bottom wall is spirally distributed around the axis of the nut body.

Abstract: A preparation method of a rhodium octanoate dimer includes the following steps: (1) mixing RhCl3 with an alkali metal octanoate uniformly to get a first solution; (2) adding a reductant into the first solution obtained from step (1), and heating for reflux reaction to get a second solution; (3) adding the second solution obtained from step (2) into deionized water while hot, continuing to stir, and performing a suction filtration to get a crude product; and (4) performing a primary washing, a secondary washing, a filtration, and a drying on the crude product obtained from step (3) to get a rhodium octanoate dimer as a green solid.

Abstract: Provided herein are sulfo n-hydroxysuccimidyl ester (sulfo-SE) linked peptides, methods of synthesis thereof, and methods of using such peptides for labeling of biomolecules. In particular, peptides comprising non-alkyl group such as serine, threonine, cysteine, tyrosine, glutamic acid, and aspartic acid are stably modified (e.g., without autoreactivity) with a sulfo-SE group and used to label or otherwise modify biomolecules.