Abstract: The present invention relates to novel cross-linked cytotoxic agents, pyrrolobenzodiazepine dimer (PBD) derivatives, and their conjugates to a cell-binding molecule, a method for preparation of the conjugates and the therapeutic use of the conjugates.

Abstract: The present invention discloses a bead wire wrapper device and a wrapper method.

Abstract: A semiconductor device includes a semiconductor body having a base region incorporating a field stop zone where the base region and the field stop zone are both formed using an epitaxial process. Furthermore, the epitaxial layer field stop zone is formed with an enhanced doping profile to realize improved soft-switching performance for the semiconductor device. In some embodiments, the enhanced doping profile formed in the field stop zone includes varying, non-constant doping levels. In some embodiments, the enhanced doping profile includes one of an extended graded doping profile, a multiple stepped flat doping profile, or a multiple spike doping profile. The epitaxial layer field stop zone of the present invention enables complex field stop zone doping profiles to be used to obtain the desired soft-switching characteristics in the semiconductor device.

Abstract: Wireless communications systems and methods related to allocating resource blocks and resource block groups in a system band in order to reduce overhead associated with resource allocation. To reduce overhead, the wireless communication device communicates a signal in a control channel that indicates a general area and a resource block in the general area that stores data. The wireless communication device then communicates multiple resource blocks that include the resource block and communicates the data in the resource block using the signal. To reduce overhead, the wireless communication device also communicates multiple mappings for each resource block group into a set of resource blocks and a signal in a control channel that selects one of the multiple mappings. The communication device then determines resource blocks that are included in the resource block group according to the mapping, and communicates data in these resource blocks.

Abstract: The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)-or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and/or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.

Abstract: A UE may be configured to communicate using one of analog beamforming or hybrid beamforming. The UE may receive a set of beamformed signals from a base station. The UE may determine a set of angular spread values associated with a set of clusters in a channel between the base station and the UE based on the set of beamformed signals received from the base station. The UE may transmit the set of angular spread values to the base station. The UE may receive, from the base station based on the set of angular spread values, a set of transmission ranks associated with at least one cluster of the set of clusters. The UE may communicate at least one data stream with the base station across the at least one cluster using the set of transmission ranks associated with the at least one cluster of the set of clusters.

Abstract: The disclosure relates to a shading tape, a backlight unit and a display device. The shading tape includes: a tape body; a buffer layer located at a side of the tape body and provided with a through groove running through the buffer layer in a direction perpendicular to the tape body; a heat dissipating component located in the through groove; and a sealing layer located at a side of the buffer layer far away from the tape body and configured to close an opening of the through groove at the side of the buffer layer far away from the tape body.

Abstract: The present disclosure relates to semiconductor structures and, more particularly, to stacked gate transistors and methods of manufacture. The structure includes a stacked gate structure having a plurality of transistors with at least one floating node and at least one node to either ground or a supply voltage, and a contact to either of the ground or supply voltage and the at least one floating node being devoid of any contact.

Abstract: A gas phase rust-resisting material for various metals includes, calculated in parts by weight, following components of: 78.5 to 95.5 parts of benzotriazole, 78.5 to 95.5 parts of dicycloethylamine nitrite, 500 to 800 parts of octadecylamine, 9000 to 11000 parts of ethanol, 33.5 to 38.5 parts of a reinforcing agent and 23.5 to 25.5 parts of a rust-resistant microcapsule. Further disclosed is a method for preparing the gas phase rust-resisting material which is suitable for various metals.

Abstract: Wireless communications systems and methods related to allocating resource blocks and resource block groups in a system band in order to reduce overhead associated with resource allocation. To reduce overhead, the wireless communication device communicates a signal in a control channel that indicates a general area and a resource block in the general area that stores data. The wireless communication device then communicates multiple resource blocks that include the resource block and communicates the data in the resource block using the signal. To reduce overhead, the wireless communication device also communicates multiple mappings for each resource block group into a set of resource blocks and a signal in a control channel that selects one of the multiple mappings. The communication device then determines resource blocks that are included in the resource block group according to the mapping, and communicates data in these resource blocks.

Abstract: A method of fabricating a semiconductor device is provided, which includes providing a plurality of fins over a substrate and forming a plurality of first gate structures having a first gate pitch and a plurality of second gate structures having a second gate pitch traversing across a first and a second set of fins, respectively. The second gate pitch is wider than the first gate pitch. Epitaxial regions are formed between adjacent second gate structures in the second set of fins. A dielectric layer is deposited over the second gate structures and the epitaxial regions. Contact openings are formed in the dielectric layer. At least one of the contact openings is formed over the second gate structure where the second gate structure traverses across the second set of fins. The contact openings are filled with a conductive material to form contact structures electrically coupled to the second gate structures.

Abstract: The present invention is related to novel cytotoxic agents, derivatives of Amanita toxins of Formula (I), wherein , -----, R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, X, L, m, n and Q are defined herein, the preparation and the therapeutic uses in the targeted treatment of cancers, autoimmune disorders, and infectious diseases.

Abstract: The aerator system incorporates a land-based or water-based floating solar activated water aeration system with integrated linear diaphragm air compressor and controller to provide improved oxygen addition into water. The system uses low voltage and an advanced controller with max power point tracking (MPPT) technique, which converts the solar panel photovoltaic low voltage DC to low voltage AC and allows power generated from each solar panel to be fully utilized.

Abstract: A solid state disk packaging line, for packaging solid state disks, includes a stacking tray conveying system, a packaging system, a packaging box conveying system, and a packaging box packaging system. The packaging system includes a packaging box loading device, a sealing bag loading device, and a packaging machine. Two sides of the packaging system provided with the packaging machine are connected with the stacking tray conveying system and the packaging box conveying system respectively. The packaging machine receives stacking trays, and loads the stacking trays into a packaging box, and then transfers the packaging box to the packaging box packaging system via the packaging box conveying system. The packaging box with the stacking trays loaded therein is sealed by the packaging box packaging system. The packaging line packages and seals the packaging box without manual work which protects solid state disks, avoids doing damage, and improves production efficiency.

Abstract: The present invention relates to the conjugation of a tubulysin analog compound to a cell-binding molecule with branched/side-chain linkers for having better delivery of the conjugate compound and targeted treatment of abnormal cells. It also relates to a branched-linkage method of conjugation of a tubulysin analog molecule to a cell-binding ligand, as well as methods of using the conjugate in targeted treatment of cancer, infection and autoimmune disease.

Abstract: The present invention relates to novel linkers containing a 2,3-disubstituted succinic group, or 2-monosubstituted, or 2,3-disubstituted fumaric or maleic (trans (E)- or cis (Z)-butenedioic), or acetylenedicarboxyl group for conjugation of a cytotoxic agent, and/or one or more different functional molecules per linker to a cell-binding molecule, through bridge linking pairs of thiols on the cell-binding molecule specifically. The invention also relates to methods of making such linkers, and of using such linkers in making homogeneous conjugates, as well as of application of the conjugates in treatment of cancers, infections and autoimmune disorders.

Abstract: Methods, systems, and devices for wireless communication are disclosed. Flexible interleaving configurations may be employed to support various operations, including beamforming. Flexible interleaving may include dynamically or semi-statically determining a combination of bit-level, tone-level, tone-group level, or other interleaving technique for one or more transmissions. The interleaving configuration may be based on delay spread, a coherence bandwidth, a signal to noise ratio, a Doppler spread, or a combination thereof. An interleaving configuration may be a determination may be made by a base station or some other network entity and explicitly signaled to another device. Additionally or alternatively, the determination may be made based on one or more implicit rules, which may be based on a variety of factors (e.g., available bandwidth, modulation and coding scheme (MCS), code block (CB) size). Further, interleaving may be enabled (or disabled) under certain conditions.