Abstract: A data storage device includes a data storage medium and a controller. The controller performs a boot-up sequence that includes operations that transition the data storage device from a lower operational state to a higher operational state in which the data storage device is ready to service host commands. The controller also carries out metadata updating operations independently of the boot-up sequence operations. Carrying out the metadata updating operations independently of the boot up sequence operations prevents the metadata updating operations from substantially contributing to a boot-up time.

Abstract: A data storage device includes a main storage memory and a non-volatile cache memory system. The non-volatile cache memory system comprises a master device, a first slave device communicatively coupled to the master device, the first slave device comprising a first non-volatile memory, and a second slave device communicatively coupled to the master device, the second slave device comprising a second non-volatile memory of a different type than the first non-volatile memory. The data storage device also includes a controller communicatively coupled to the main storage memory and to the non-volatile cache memory system, the controller is configured to, upon a power loss to the data storage device, store volatile data into the non-volatile cache memory system.

Abstract: The present disclosure relates to the field of solid-state data storage, and particularly to improving the speed performance of solid-state data storage devices by reducing multi-stream data write collision. A method according to embodiments includes: writing a plurality of data chunks in a skewed sequence from a plurality of different data write buffers in the storage device into a plurality of different super-pages across all channels of the storage device.

Abstract: A method of combined file firmware upgrade includes providing a combo file comprising a plurality of firmware files for a plurality of data storage device product categories. The method also includes downloading the combo file to a data storage device that belongs to one of the plurality of data storage device product categories. The method further includes comparing parameters of the data storage device with parameters of individual firmware files of the plurality of firmware files. When parameters of a particular one of the plurality of firmware files are found to correspond with the parameters of the data storage device, the method includes utilizing the particular one of the plurality of firmware files to perform an automatic firmware upgrade in the data storage device.

Abstract: A data storage device includes a first memory section with a reserved area having stored therein an event trigger log that includes a history of past logged events. The data storage device also includes a second memory section separate from the first memory section. The data storage further includes a controller that, upon power up of the data storage device and before the data storage device is ready to receive host commands, allocates a buffer in the second memory section for capturing new events. The controller postpones linking of any captured new events with the past logged events until at least after the data storage device is ready to receive the host commands.

Abstract: A pick-and-place device for picking a work-piece from a first location to a second location and having force measurement is disclosed. The pick-and-place device comprises: (a) a positive pressure chamber formed among a pick-and-place holder, a force measuring membrane and a cover, wherein a positive pressure is supplied to the positive pressure chamber via a pressure supply inlet provided on the pick-and-place holder, and thus the force measuring membrane is being preloaded; (b) a vacuum chamber formed among the pick-and-place holder, the force measuring membrane and a pick-up membrane, wherein a negative pressure is provided via a vacuum supply inlet provided on the pick-and-place holder, wherein the pick-and-place device provides a pressure difference between the work-piece and the pick-and-place device, enabling a pick-and-place capability.

Abstract: Provided is an amino pyrazolopyrimidine compound as represented by the following structural formula used as a neurotrophic factor tyrosine kinase receptor inhibitor. The compound can inhibit the activity of Trk kinase and can treat diseases mediated by a Trk tyrosine kinase receptor in mammals.

Abstract: Embodiments of the present disclosure disclose a display substrate, a display panel, a display apparatus, and a method for driving a display apparatus. The display substrate includes: a plurality of first wiring groups each comprising a plurality of first wirings extending in a first direction; a plurality of second wiring groups each comprising a plurality of second wirings and at least one transmission signal line extending in a second direction crossing the first direction; a plurality of first switching circuits each connecting a plurality of first wirings in a corresponding one of the first wiring groups to a control signal line; and a plurality of second switching circuits each connecting a plurality of second wirings in a corresponding one of the second wiring groups to the control signal line.

Abstract: A data storage device that includes a data storage medium and a controller communicatively coupled to the data storage medium. The controller is configured to receive commands from a host and to detect a hung state in the data storage device. The controller is also configured to determine an execution status of a command, of the commands from the host, associated with the hung state. The controller is further configured to dynamically carry out a self-recovery operation in the data storage device to clear the hung state. The self-recovery operation includes steps that depend upon the execution status of the command associated with the hung state.

Abstract: The present invention belongs to the field of pharmaceutical chemistry, and relates to a substituted pyrrolopyrimidine CDK inhibitor, in particular to a compound as shown in formula I or a pharmaceutically acceptable salt or solvate thereof, as well as a preparation method thereof and a pharmaceutical composition thereof. The present invention also relates to the use of the compound and the pharmaceutical composition thereof in the preparation of a drug for treating diseases associated with CDK inhibition. The compound according to the present invention has a marked inhibitory effect on CDK, excellent drug absorption and significantly superior oral absorption effect.

Abstract: A method for manufacturing an array substrate includes: forming a strip-shaped barrier wall(s) on a base substrate, wherein the width of each barrier wall is less than or equal to a distance between a first metal trace to be formed and a second metal trace to be formed; and forming a first metal trace at one side of each barrier wall located in a direction perpendicular to an extending direction of the barrier wall, and forming a second metal trace at an opposite side of the barrier wall located in the direction perpendicular to the extending direction of the barrier wall.

Abstract: A high density manufacturing cell or carousel for optimizing floor space usage to reduce equipment footprint and material travel path is disclosed. The carousel allows processing and transferring of products to be concurrently performed, minimising non-productive time.

Abstract: The present application relates to the field of pharmaceutical chemistry, and in particular, to a pyrrolopyrimidine compound represented by general formula (I), a stereoisomer thereof, or a pharmaceutically acceptable salt thereof. The present invention further relates to a method for preparing the pyrrolopyrimidine compound represented by general formula (I), pharmaceutical compositions and an application of the pyrrolopyrimidine compound in treating diseases mediated by Janus Kinase.

Abstract: The present disclosure relates to aniline pyrimidine derivatives or pharmaceutically acceptable salts thereof as EGFR inhibitors, specifically relates to compounds represented by formula (I) or pharmaceutically acceptable salts, pharmaceutical compositions, the method and uses thereof for treating EGFR mediated diseases.

Abstract: A pick-and-place device for picking a work-piece from a first location to a second location and having force measurement is disclosed. The pick-and-place device comprises: (a) a positive pressure chamber forming from a pick-and-place holder, a force measuring membrane and a cover, wherein a positive pressure is supplied to the positive pressure chamber via a pressure supply inlet provided on the pick- and-place holder, and thus the force measuring membrane is being preloaded; (b) a vacuum chamber forming from the pick-and-place holder, the force measuring membrane and a pick-up membrane, wherein a negative pressure is provided via a vacuum supply inlet provided on the pick-and-place holder, wherein the pick-and-place device provides a pressure difference between the work-piece and the pick-and-place device, enabling a pick-and-place capability.

Abstract: Systems and methods for saving critical data upon power loss are described. In one embodiment, the systems and methods include performing a write operation to a first track of a storage drive, monitoring a voltage level of a storage drive to detect power loss on the storage drive while performing the write operation, identifying a track ID of a second track adjacent to the first track upon detecting power loss on the storage drive, and storing the identified track ID in a non-volatile memory on the storage drive.

Abstract: Disclosed are compounds having formulae I and II or pharmaceutically acceptable salts or hydrates thereof, a preparation method thereof and pharmaceutical compositions thereof. The compounds having formulae I and II possesses an isocitrate dehydrogenase 2 (IDH2) inhibitory activity and are capable of treating IDH2 mutation-induced cancers.

Abstract: The present application present application relates to a compound represented by Formula (III) or a pharmaceutically acceptable salt, solvent compound, active metabolite, crystal polymorph, ester, isomer, or prodrug thereof. The application further provides a pharmaceutical composition comprising the compound represented by Formula (III) and a use thereof for preparing a bromodomain inhibitor for preventing or treating various diseases, such as inflammation and cancer, related to the bromodomain.

Abstract: The present application relates to compounds represented by general formula (I), general formula (II) or general formula (III), and pharmaceutically acceptable salts or hydrates thereof, preparation methods thereof, and pharmaceutical compositions thereof. The compounds represented by general formula (I), general formula (II) or general formula (III) have inhibitory activities against isocitrate dehydrogenase 2 (IDH2), thereby being capable of treating IDH2 mutation-induced cancers.

Abstract: The present application relates to a substituted amino six-membered saturated heteroalicycle represented by formula I as a long-acting DPP-IV inhibitor, a method for preparing the same, a pharmaceutical composition comprising the same, and a use of the same in treating and/or preventing diseases and disorders benefitting from DPP-IV inhibition.