Abstract: A sensor for motion or gesture sensing may be configured to emit radio frequency signals such as for pulsed range gated sensing. The sensor may include a radio frequency transmitter configured to emit the pulses and a receiver configured to receive reflected ones of the emitted radio frequency signals. The received pulses may be processed by a motion channel and/or a gesture channel. The gesture channel may produce signals for further processing for identification of one or more different motion gestures such as by calculating and evaluating features from any of the amplitude, phase and frequency of the output signals of the gesture channel. The sensing apparatus may optionally serve as a monitor for evaluating user activities, such as by counting activities. The sensor may optionally serve as a user control interface for many different devices by generating control signal(s) based on identification of one or more different motion gestures.

Abstract: A method and a device for determining a device parameter of a hearing device to be worn at the ear of a user, the method comprising: obtaining image data of one or more images, the image data including first image data of a first image of the outer human ear at a first angle; identifying, based on the first image data, a first anatomical landmark and a second anatomical landmark of the outer human ear using a processor; identifying the position of the first anatomical landmark and the second anatomical landmark in the first image; determining the device parameter of the hearing device based on the first anatomical landmark and the second anatomical landmark; and outputting the device parameter.

Abstract: A probe generates location signals, and has an electrode at a distal end that acquires from heart chamber surface positions electrical signals due to a conduction wave traversing the surface. A processor derives LATs from the electrical signals, calculates a first time difference between LATs at a first pair of positions and a second time difference between LATs at a second pair of positions. The processor calculates first and second LAT-derived distances as products of the first and second time differences with a conduction wave velocity, identifies an arrhythmia origin at a surface location where a first difference in distances from the location to the first pair of the positions is equal to the first LAT-derived distance, and a second difference in distances from the location to the second pair of the positions is equal to the second LAT-derived distance, and marks the origin on a surface representation.

Abstract: Anatomical and functional assessment of coronary artery disease (CAD) using machine learning and computational modeling techniques deploying methodologies for non-invasive Fractional Flow Reserve (FFR) quantification based on angiographically derived anatomy and hemodynamics data, relying on machine learning algorithms for image segmentation and flow assessment, and relying on accurate physics-based computational fluid dynamics (CFD) simulation for computation of the FFR.

Abstract: Embodiments described provide an ultrasound method, and an ultrasound apparatus and computer program product operable to perform that method. In some embodiments, the method allows for provision of a multi-transducer ultrasound imaging system by providing a robust method to accurately localize the transducers in the system in order to beamform a final image. The method and apparatus described allow for improvements in imaging quality in terms of resolution, depth penetration, contrast and signal to noise ratio (SNR).

Abstract: The present invention relates to a device for endoscopy or endosonography-guided transluminal interventions whereby two luminal structures in the body may be drawn toward each other and a fluid conduit formed in between. The device may have a hollow central member to which is coupled a distal retention member and in one embodiment a proximal retention member. The retention members may each be positioned inside one of the luminal structures and expanded from a first condition to an expanded second condition having an increased radius. The length of the central member may be shortened and its diameter expanded to approximate the two retention members and thereby the luminal structures.

Abstract: Disclosed is the electronic architecture, including component arrangement and use of switches, and power saving method for use in a dual mode USTA instrumentation. In an embodiment, the instrument architecture includes US and TA analog components, including a transducer, TA preamplifier, pulser, switches, and AFE (or ADC with programmable amplifier) arranged in a way which allows efficient usage of the same transducer elements, electronic components, wiring, and AFE channels in both US and TA modalities. The operation with fast power control over the TA preamplifier is described, which allows turning off the TA preamplifier power between TA measurements cycles with or without US measurement between TA measurements. TA preamplifier energy saving allows such designs to reduce TA preamplifier power consumption many times, which enables TA preamplifier integration inside transducer housing or probe housing, and/or the use of the TA preamplifier in portable battery-operated or hand-held devices.

Abstract: A system and method for generating at least one optimized functional images of a lesion region of a subject is provided. The system includes a diffuse optical tomography (DOT) device, and a computing device. The DOT device is configured to acquire lesion functional data of an imaging volume including the lesion region of the breast and reference functional data from a corresponding imaging volume including healthy tissue within a contralateral breast. The computing device is programmed to generate at least one functional image of the breast by reconstructing the functional data at the plurality of regions including the lesion region and the surrounding adjacent background region. The functional images may be reconstructed by an optimization method regularized a preliminary estimate generated by applying a truncated pseudoinverse matrix of a weight matrix to the functional data. The optimized functional images relate to levels of hemoglobin at the voxels.

Abstract: In a non-invasive optical detection system and method, sample light is delivered into a scattering medium. A first portion of the sample light passing through a volume of interest exits the scattering medium as signal light, and a second portion of the sample light passing through a volume of non-interest exits the scattering medium as background light that is combined with the signal light to create a sample light pattern. Reference light is combined with the sample light pattern to create an interference light pattern having a holographic beat component. Ultrasound is emitted into the volume of non-interest in a manner that decorrelates the background light of the sample light pattern from the holographic beat component. The holographic beat component is detected during the measurement period. An optical parameter of the volume of interest is determined based on the detected holographic beat component.

Abstract: A signal processing apparatus relays communication of control signals between a controller and a plurality of processing modules, and includes: a communication device configured to perform communication of the control signals with the plurality of processing modules; a plurality of first storages provided respectively to correspond to the plurality of processing modules, the plurality of first storages being configured to store the control signals written by the controller; a second storage configured to store: address information indicating each communication address assigned to each of the plurality of processing modules; and correspondence information indicating correspondence relationships between the plurality of first storages and a plurality of module-side storages respectively included in the plurality of processing modules; and a synchronization processor configured to synchronize the plurality of first storages with the plurality of corresponding module-side storages via the communication device bas

Abstract: A method is for controlling a medical imaging system. The method includes providing a data record for a patient, the data record including indication data; mapping at least the indication data into an ontology; providing a control data library including control data records for at least one medical imaging system; automatically determining a control data record from the control data library as a function of the at least indication data mapped into the ontology, via at least one of an inference and numerical modeling; and controlling the medical imaging system with the control data record automatically determined. Furthermore, a related control facility and a medical imaging system are also disclosed.

Abstract: A fluid separation device includes a centrifuge in which a fluid is separated into at least two components, with an interface therebetween. At least a portion of one of the separated fluid components is removed from the centrifuge and flows through a vessel. Light is reflected off of the separated fluid component in the vessel and received and analyzed to determine its main wavelength. If the main wavelength is higher than a maximum value, a target location of the interface is changed. If the main wavelength is less than the maximum value, then the location of the interface is compared to the target location. When the interface is sufficiently close to the target location, the optical density of the separated fluid component in the vessel is compared to a minimum value. If the optical density is less than the minimum value, the target location of the interface is changed.

Abstract: Systems and methods for reconstructing medical images are disclosed. Measurement data from positron emission tomography (PET) data, and measurement data from an anatomy modality, such as magnetic resonance (MR) data or computed tomography (CT) data, is received from an image scanning system. A PET image is generated based on the PET measurement data, and an anatomy image is generated based on the anatomy measurement data. A trained neural network is applied to the PET image and the anatomy image to generate an attenuation map. The neural network may be trained based on anatomy and PET images. In some examples, the trained neural network generates an initial attenuation map based on the anatomy image, registers the initial attenuation map to the PET image, and generates an enhanced attenuation map based on the registration. Further, a corrected image is reconstructed based on the generated attenuation map and the PET image.

Abstract: Pre-surgical planning can use a three-dimensional model of an anatomical structure having a plurality of fiduciary points and a surgical mark integrated into the three-dimensional model using a contrast material. A model image of the three-dimensional model can be superimposed with a diagnostic image of the anatomical structure using the plurality of fiduciary points in order to create a superimposed image.

Abstract: A dual modality endocavity imaging and treatment system for detection of cancer and targeted biopsy and treatment procedures, comprising: a housing; a nuclear detector system housed within the housing and configured for detecting nuclear radiation imaging data; an ultrasound detector system housed within the housing for detecting ultrasound imaging data; a needle associated with the housing and adjustably positionable relative thereto; and a data processing module configured to receive the nuclear radiation imaging data and the ultrasound imaging data and to generate and output an image showing the relative position of the needle and an endocavity object of interest. The needle may include a distinct radiation signature to facilitate imaging thereof.

Abstract: A method for locating a vessel, the method comprising illuminating at least a portion of the vessel with a background light having a substantially high susceptibility to absorption by particles in said portion of the vessel; detecting backscattered light from said illuminated portion of the vessel; reproducing an image from said backscattered light; and identifying dark regions within said reproduced image.

Abstract: A mm-wave system includes transmission of a millimeter wave (mm-wave) signal by a plurality of transmitters to multiple objects, and receiving of return—mm-wave signals from the multiple objects by a plurality of receivers. A processor is configured to perform an algorithm to derive complex-valued samples and angle measurements from each receiver to identify one object from another object. The processor further extracts signal waveforms that correspond to each object and process the extracted signal waveforms to estimate breathing rate and heart rate of the identified object.

Abstract: A system and method for the use of the results from a structural analysis of a patient's bone from a clinical scan, to be used clinically to manage patients in a widespread and consistent fashion.

Abstract: A medication inventory system may include a medication tray that includes partitions defining compartments and having a tray identifier associated therewith, and each compartment may store a respective medication. The system may include an imaging apparatus, and a processor and an associated memory cooperating with the imaging apparatus to determine the tray identifier of the medication tray, and maintain in the memory a desired respective medication within each compartment based upon the tray identifier. A respective medication image of the medication within each compartment may be obtained and machine learning may be used to determine a medication within each compartment based upon the respective medication image.

Abstract: An MR Spectroscopy (MRS) system and approach is provided for diagnosing painful and non-painful discs in chronic, severe low back pain patients (DDD-MRS). A DDD-MRS pulse sequence generates and acquires DDD-MRS spectra within intervertebral disc nuclei for later signal processing and diagnostic analysis. An interfacing DDD-MRS signal processor receives output signals of the DDD-MRS spectra acquired and is configured to optimize signal-to-noise ratio by an automated system that selectively conducts optimal channel selection, phase and frequency correction, and frame editing as appropriate for a given acquisition series. A diagnostic processor calculates a diagnostic value for the disc based upon a weighted factor set of criteria that uses MRS data extracted from the acquired and processed MRS spectra for multiple chemicals that have been correlated to painful vs. non-painful discs. A display provides an indication of results for analyzed discs as an overlay onto a MRI image of the lumbar spine.

Abstract: Methods and systems for clinical report generation. One system includes an electronic processor configured to receive a query image and determine a similarity metric for a plurality of medical images, where the similarity metric represents a similarity between the query image and each of the plurality of medical images. The electronic processor is also configured to determine a predetermined number of medical images from the plurality of medical images based on the similarity metric for each of the plurality of medical images. The electronic processor is also configured to rank a plurality of reports, where each of the plurality of reports correspond to one of the predetermined number of medical images. The electronic processor is also configured to generate a clinical report including information extracted from at least one of the plurality of reports based on the ranking of the plurality of reports.

Abstract: A nervous tissue imaging system and a method therefor. The system includes: a housing containing an excitation light source, optically coupled with a source optical train, the excitation light source emits excitation light in a first wavelength range, which can be in a near ultraviolet light range, to illuminate a tissue region of interest including healthy nervous tissue and healthy non-nervous tissue. The excitation light in the first wavelength range causes the healthy nervous tissue, in response to being illuminated with the excitation light, to endogenously autoflouresce and emit first autofluorescence light at a first luminance in a second wavelength range. The healthy non-nervous tissue, in response to being illuminated with the excitation light, either avoids emitting any autofluorescence light in the second wavelength range; or endogenously autoflouresces and emits second autofluorescence light in the second wavelength range at a second luminance that is lower than the first luminance.

Abstract: A method of radiotherapy treatment planning involves dynamic target tracking and beam redirection. A set of 3D images of a patient reflecting a movement of the patient is obtained, and each image is deformably registered with one reference image. The accumulated dose is calculated as the sum of the dose distribution over all phases in dependence of the patient movement and the model of the delivery machine, the dose distribution for each phase being deformed by means of the deformation map for the respective phase, to match the reference image.

Abstract: A system for surgical registration. The system may include at least one computing device in communication with a surgical navigation system and the surgical device. The at least one computing device: a) receiving external bone registration data corresponding to locations on the exterior surface of the femur; b) calculating a first registration transform based on the external bone registration data; c) transforming a first bone removal plan of a surgical plan to the operative coordinate system based on the first registration transform; d) receiving internal bone canal registration data corresponding to at least one of location or orientation data from the inner canal of the femur; e) calculating a second registration transform based on both of the external and internal bone canal bone registration data; and f) transforming a second bone removal plan of the surgical plan to the operative coordinate system based on the second registration transform.

Abstract: Disclosed are various examples and embodiments of systems, devices, components and methods configured to detect a location of a source of at least one cardiac rhythm disorder in a patient's heart. In some embodiments, electrogram signals am acquired from inside a patient's heart, and subsequently normalized, adjusted and/or filtered, followed by generating a two-dimensional (2D) spatial map, grid or representation of the electrode positions, processing the amplitude-adjusted and filtered electrogram signals to generate a plurality of three-dimensional electrogram surfaces corresponding at least partially to the 2 D grid, one surface being generated for each or selected discrete times, and processing the plurality of three-dimensional electrogram surfaces through time to generate a velocity vector map corresponding at least partially to the 2 D grid.

Abstract: A system and method may be used to evaluate soft tissue. A knee arthroplasty soft tissue evaluation may use an adjustable spacer, such as varying sized physical spacers or an inflatable bladder, along with a sensor to measure force, pressure, gap distance, or the like during a range of motion test. A method may include maintaining an equal pressure or gap distance for a medial component and a lateral component of an adjustable spacer during a range of motion test. Information, including, for example a maximum or minimum gap distance or pressure may be determined during the range of motion test. The determined information may be output for display or used to update a surgical plan.

Abstract: Machine-based risk prediction or assistance is provided for peri-procedural complication, such as peri-procedural myocardial infarction (PMI). A machine-learned model is used to predict risk of PMI and/or recommend courses of action to avoid PMI in PCI. Various combinations of types or modes of information are used in the prediction, such as both imaging and non-imaging data. The prediction may be made prior to, during, and/or after PCI using the machine-learned model to more quickly reduce the chance of PMI. The workflows for prior, during, and/or post PCI incorporate the risk prediction and/or risk-based recommendations to reduce PMI for patients.

Abstract: A system and method for generating reports on perfusion blood volume from computed tomography (CT) data acquired from a subject. The method includes receiving multi-faceted CT data acquired from the subject using one of a multi-energy or polychromatic CT acquisition and deriving an iodine concentration in an artery feeding a volume of interest (VOI) in the multi-faceted CT data. The method further includes determining an effective atomic number of a spatial distribution in the VOL calculating a perfused blood volume of the VOI using the iodine concentration and the effective atomic number, and generating a report of the perfused blood volume of the VOI.

Abstract: Systems and methods are disclosed herein for processing ultrasound images to identify objects for diagnostic and/or interventional use. For instance, an ultrasound image of an anatomical structure may be received from a computing device of an ultrasound imaging system. The ultrasound image may be input to a machine learning model that is trained to identify a plurality of objects in ultrasound images of the anatomical structure. The plurality of objects may include anatomical features, disruptive features, and/or instruments. A prediction of one or more objects from the plurality of objects identified in the ultrasound image may be received as output of the machine learning model. An indication of the prediction may be provided to the computing device for display on a display of the ultrasound imaging system.

Abstract: A hyperspectral imaging system can include a first hyperspectral imaging camera that is configured to provide first hyperspectral image data of an object in a first field of view. A second hyperspectral imaging camera can be separated from the first hyperspectral imaging camera, where the second hyperspectral imaging camera is configured to provide second hyperspectral image data of the object in a second field of view. A processor circuit can be operatively coupled to the first and second hyperspectral imaging cameras, where the processor circuit configured to combine the first and second hyperspectral image data to generate a hypercube of data for the object comprising spectral data included in the first and second hyperspectral image data.

Abstract: A scanner includes a camera, a light source for generating a probe light incorporating a spatial pattern, an optical system for transmitting the probe light towards the object and for transmitting at least a part of the light returned from the object to the camera, a focus element within the optical system for varying a position of a focus plane of the spatial pattern on the object, unit for obtaining at least one image from said array of sensor elements, unit for evaluating a correlation measure at each focus plane position between at least one image pixel and a weight function, a processor for determining the in-focus position(s) of each of a plurality of image pixels for a range of focus plane positions, or each of a plurality of groups of image pixels for a range of focus plane positions, and transforming in-focus data into 3D real world coordinates.

Abstract: Proposed is a technique for performing sexing of a fertilized egg with a high sexing rate at a high speed, based on image data obtained by photographing a contour of the egg. In particular, a fertilized egg sexing method, a fertilized egg sexing apparatus and a program for making a female/male judgment of a fertilized egg according to a contour of the fertilized egg by a computer are proposed. The fertilized egg sexing method includes: extracting the contour based on image data obtained by photographing the fertilized egg at different angles, calculating a short radial from the contour, calculating short radial phase differences corresponding to photographing at the angles, and making a female/male judgment using the short radial phase differences.

Abstract: Multi-sequence scanning methods and apparatuses, devices and CT systems are described. A multi-sequence scanning method may include: in response to a parameter configuration command, configuring scan sequence parameters for a plurality of scan sequences in a scan protocol to obtain a target scan protocol, where the scan sequence parameters include a scan start time and a scan duration of each of the scan sequences, and a scan switching duration between the scan sequences, where a total scan duration of the scan sequences in the target scan protocol is configured to be less than or equal to a preset total scan duration, and where the scan switching duration between the scan sequences is configured in a shortest duration mode; and in response to receiving a scan command, controlling the CT system to scan a scanned object according to the scan sequence parameters configured in the target scan protocol.

Abstract: The systems and methods can accurately and efficiently determine boundary conditions for an arterial segment and thereby efficiently determine hemodynamic information for that segment. The method may include receiving medical image data of a patient. The method may further include generating a geometrical representation of the one or more arterial segments from the medical image data. The method may further include determining boundaries and geometry data for each arterial segment. The method may further include determining boundary conditions for the inflow boundary and each outflow boundary. The boundary conditions for each outflow boundary may be determined using an outflow distribution parameter. The outflow distribution parameter may be determined using the geometry data for one or more of the one or more outflow boundaries, stored hemodynamic data, or a combination thereof. The method may further include determining flow field for each arterial segment and determining hemodynamic information.

Abstract: A system and method may be used to evaluate soft tissue. A hip joint evaluation may use an adjustable spacer, such as varying sized physical spacers or an inflatable bladder, along with a sensor to measure force, pressure, gap distance, or the like, for example during a range of motion test. A method may include using a maximum pressure during the range of motion test to determine a maximum pressure during the range of motion test. The maximum pressure may be output for display on a user interface.

Abstract: Systems and methods for robotically distracting a disc space are provided for implantation of an intervertebral prosthetic disc. The system includes a 3D modeling system for creating a 3D model of first and second vertebra adjacent the disc space and identifying positions of the first and second vertebrae. A robotic distractor precisely opens the disc space just large enough to receive a selected intervertebral disc. A computing system stores and processes the 3D model and the positions of the first and second vertebrae before and after distraction. A surgeon interface on the computing system allows the surgeon to select an intervertebral disc prosthesis to be implanted and a desired distraction distance or force to be achieved.

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on an overlay on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

Abstract: A cryosurgical system including a computer system programmed with software configured to perform the following steps: a) capturing at least one first view of a region of interest in a human body; b) capturing at least one second view of the region of interest; c) outlining the region of interest and at least one area outside the region of interest with the assistance of an operator; d) constructing a 3-dimensional model of the region of interest and the at least one area outside the region of interest utilizing the at least one first view and the at least one second view of the region of interest; and e) utilizing the 3-dimensional model of the region of interest and the at least one area outside the region of interest to determine at least one cryosurgical probe placement location.

Abstract: An image processing apparatus (10) is disclosed that comprises a processor arrangement (16) adapted to receive image data corresponding to a region of interest (1) of a patients cardiovascular system, said image data comprising a temporal sequence (15) of intravascular ultrasound images acquired (150) at different phases of at least one cardiac cycle of said patient, said intravascular ultrasound images imaging overlapping volumes of the patient's cardiovascular system; implement a spatial reordering process of said temporal sequence of intravascular ultrasound images by evaluating the image data to select at least one spatial reference (6, Vref) associated with said temporal sequence of intravascular ultrasound images; estimating a distance to the at least one spatial reference for each of the intravascular ultrasound images of said temporal sequence; and reordering said temporal sequence of intravascular ultrasound images into a spatial sequence of intravascular ultrasound images based on the estimated dist

Abstract: A system for determining a location for a surgical procedure, having a 3D spatial mapping camera, the 3D spatial mapping camera configured to map a bone. The system also includes a marker attached to a distal end section of the bone, such that the 3D spatial mapping camera is configured to capture a plurality of images of the marker as the bone is rotated in a non-linear path. The images also include data identifying a location of the marker. The system also includes a computer system that receives the data from the images captured by the 3D spatial mapping camera and determines a location of a mechanical axis of the bone, and a mixed reality display, where the computer system is configured to send the location of the mechanical axis to the mixed reality display and the mixed reality display is configured to provide a virtual display of the mechanical axis of the bone.

Abstract: A robotic surgical system for performing surgery, the system includes a robotic arm having a force and/or torque control sensor coupled to the end-effector and configured to hold a first surgical tool. The robotic system further includes an actuator that includes controlled movement of the robotic arm and/or positioning of the end-effector. The system further includes a tracking detector having optical markers for real time detection of (i) surgical tool position and/or end-effector position and (ii) patient position. The system also includes a feedback system for moving the end effector to a planned trajectory based on the threshold distance between the planned trajectory and the actual trajectory.

Abstract: A system for processing breast tissue images includes an image processing computer and a user interface operatively coupled to the image processing computer, wherein the image processing computer is configured to obtain image data of breast tissue, processing the image data to generate a set of reconstructed image slices, the reconstructed image slices collectively depicting the breast tissue, process respective subsets of the reconstructed image slices to generate a set of image slabs, each image slab comprising a synthesized 2D image of a portion of the breast tissue obtained from a respective subset of the set of reconstructed image slices.

Abstract: A system for identifying and ameliorating body degradations, the system comprising a computing device, wherein the computing device is configured to receive biological extraction data. Computing device may generate, as a function of a degradation machine-learning model and the biological extraction data, a degradation profile. Computing device may calculate a biological degradation function that is a mathematical function that describes the change in rate of degradation over time corresponding to the user. Computing device may identify, using a degradation imbalance machine-learning process and the degradation profile, a degradation imbalance. Computing device may determine, as a function of the degradation imbalance machine-learning process and the degradation imbalance, a degradation antidote strategy to decrease the rate of biological degradation of a user by performing a simulation.

Abstract: A patient side cart for a teleoperated surgical system may comprise a column extending from a base, the column having a first end connected to the base and a second end opposite the first end. The patient side cart may further include a surgical instrument manipulator arm coupled proximate the second end of the column, and an obstacle indication system comprising an illumination source mounted on the patient side cart at a height above a location the surgical instrument manipulator arm is coupled to the second end of the column, the height being measured in a direction the column extends from the base.

Abstract: In some embodiments, data sensed and/or operational parameters used during a catheterization procedure are used in the motion frame-rate updating and visual rendering of a simulated organ geometry. The organ geometry is rendered as a virtual material using a software environment (preferably a graphical game engine) which applies simulated optical laws to material appearance parameters affecting the virtual material's visual appearance, as part of simulating a scene comprising the simulated organ geometry, and optionally also comprising simulated views of a catheter probe used for sensing and/or treatment. Optionally, measurements of and/or effects on tissue by sensing and/or commanded probe-tissue interactions are converted into material appearance changes, allowing dynamic visual simulation of intra-body states and/or events based on optionally non-visual input data.

Abstract: A medical system, usable for example in connection with a dialysis apparatus, may utilize radar waves for monitoring a patient, a medical area, or an object. The medical system includes at least one sending device for sending radar waves, and at least one receiving device for receiving reflected radar waves. The medical system further includes an evaluation unit for evaluating the reflected radar waves which have been received by the at least one receiving device, resulting in obtaining a result, and an output device for outputting the result or a signal based on the result.

Abstract: Systems and methods are provided for computer aided phenotyping of fibrosis-related conditions. A digital image indicates presence of collagens in a biological tissue sample. The image is processed to quantify parameters, each parameter describing a feature of the collagens that is expected to be different for different phenotypes of fibrosis. At least some features are tissue level features that describe macroscopic characteristics of the collagens, morphometric level features that describe morphometric characteristics of the collagens, and texture level features that describe an organization of the collagens. At least some of the plurality of parameters are statistics associated with histograms corresponding to distributions of the associated parameters across at least some of the digital image. At least some of the plurality of parameters are combined to obtain one or more composite scores that quantify a phenotype of fibrosis for the biological tissue sample.

Abstract: A medical image display apparatus for displaying medical images of a lung on a screen includes a network interface receiving positional information of a navigation instrument from a position sensor of the navigation instrument, a video stream from an optical sensor of the navigation instrument, and medical images from an imaging device, a memory storing a plurality of medical images and instructions, a processor executing the instructions, and a display dynamically displaying images on the screen. The instructions, when executed by the processor, cause the medical image display apparatus to determine whether status information indicates a pathway reviewing mode, a target management mode, or a navigation mode. The instructions, when executed by the processor, further cause the display to dynamically select and update images, which are displayed on the screen, among the plurality of medical images based on the positional information of the navigation instrument and status information.

Abstract: Systems and methods for designing and implementing patient-specific surgical procedures and/or medical devices are disclosed. An example method includes obtaining, first multi-dimensional image data of an anatomical region of a patient in a first loading state; determining, from the first multi-dimensional image data, regions corresponding to anatomic elements of a spine; identifying, in each region, a first set landmarks; obtaining, a second multi-dimensional image data of the anatomical region comprising the spine of the patient in a second loading state; identifying a second set of landmarks from the second multi-dimensional image data that map to the first set of landmarks; obtaining an aligned multi-dimensional image data of the patient's spine; generating a design for a medical implant based on spinopelvic parameters measured from the aligned multi-dimensional image data; and causing a medical implant to be manufactured by sending the design for the medical implement to a manufacturing device.

Abstract: Disclosed are systems, methods, and media capable of generating emergency predictions. The systems, methods, and media generate spatiotemporal emergency communication predictions, carry out data augmentation, detect emergency anomalies, optimize emergency resource allocation, or any combination thereof.