Using Fiducial Marker Patents (Class 600/414)
  • Patent number: 11931116
    Abstract: A method for guiding resection of local tissue from a patient includes generating at least one image of the patient, automatically determining a plurality of surgical guidance cues indicating three-dimensional spatial properties associated with the local tissue, and generating a visualization of the surgical guidance cues relative to the surface. A system for generating surgical guidance cues for resection of a local tissue from a patient includes a location module for processing at least one image of the patient to determine three-dimensional spatial properties of the local tissue, and a surgical cue generator for generating the surgical guidance cues based upon the three-dimensional spatial properties. A patient-specific locator form for guiding resection of local tissue from a patient includes a locator form surface matching surface of the patient, and a plurality of features indicating a plurality of surgical guidance cues, respectively.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: March 19, 2024
    Assignee: THE TRUSTEES OF DARTMOUTH COLLEGE
    Inventors: Venkataramanan Krishnaswamy, Richard J. Barth, Jr., Keith D. Paulsen
  • Patent number: 11925419
    Abstract: The present disclosure is related to systems and methods for position determination. The method includes obtaining, via a plurality of sensors, real-time target magnetic field information of a target subject. The plurality of sensors may be configured on the target subject. The target subject may be located in a reference magnetic field in a medical system. The method includes determining real-time target position information of the target subject based on the real-time target magnetic field information of the target subject and magnetic field distribution information of the reference magnetic field in the medical system.
    Type: Grant
    Filed: October 28, 2021
    Date of Patent: March 12, 2024
    Assignee: SHANGHAI UNITED IMAGING HEALTHCARE CO., LTD.
    Inventors: Xinyue Zhang, Tuoyu Cao
  • Patent number: 11915420
    Abstract: A method is disclosed for obtaining an image biomarker that quantifies the quality of the trabecular structure of bones. The method includes: retrieving high-resolution CT (Computed Tomography) and/or MRI (Magnetic Resonance Imaging) trabecular images from an image database; pre-processing and post-processing the high-resolution CT and/or MRI trabecular images and obtaining the unique image biomarker “QTS”. Pre-processing may include: calculating the region of interest “ROI”; calculating the bone fraction map; eliminating the partial volume effect; and, binarizing. Post-processing may include: skeletonisation and extraction of morphological and structural characteristics. Lastly, the unique image biomarker “QTS” is defined as: QTS=0.7137*Comp1+0.2863*Comp2.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: February 27, 2024
    Assignees: Fundación para la Investigación del Hospital Universitario La Fe de la Comunidad Valenciana, QUIBIM, S.L., UNIVERSIDAD DE ZARAGOZA
    Inventors: Angel Alberich Bayarri, Fabio García Castro, Amadeo Ten Esteve, Luis Martí Bonmatí, María Ángeles Pérez Ansón
  • Patent number: 11864856
    Abstract: Methods and systems of registering a model of one or more anatomic passageways of a patient to a patient space are provided herein. An exemplary method may include accessing a set of model points of the model of the passageways, the model points being associated with a model space, collecting measured points along a length of a catheter inserted into the passageways of the patient, the measured points determined by a shape of the catheter, and assigning points of the first set to a plurality of subsets. The exemplary method may further include registering each of the subsets with the model points to produce a plurality of registration candidates, comparing the candidates to identify an optimal subset associated with an optimal registration of the plurality of candidates that translates the set of model points and at least one set of the sets of measured points into a common space.
    Type: Grant
    Filed: January 13, 2023
    Date of Patent: January 9, 2024
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Timothy D. Soper, Vincent Duindam
  • Patent number: 11806178
    Abstract: A CPU acquires a radiographic image obtained by imaging an imaging region where a patient is present, with a radioscopy apparatus using radiation emitted from a radiation source and applied to an irradiation field adjusted by a collimator. The CPU specifies a structure image that is included in the radiographic image and represents a structure of a specific shape having transmittance of radiation lower than the patient, based on the specific shape. The CPU executes image processing corresponding to the structure image on a patient image region imaged by a radioscopy apparatus in a case where an irradiation field excluding a position of the structure is set as the irradiation field, in a region in the radiographic image.
    Type: Grant
    Filed: June 3, 2021
    Date of Patent: November 7, 2023
    Assignee: FUJIFILM CORPORATION
    Inventor: Koichi Kitano
  • Patent number: 11786307
    Abstract: One or more devices, systems, methods and storage mediums for performing medical procedure (e.g., needle guidance, ablation, biopsy, etc.) planning and/or performance, and/or for performing visualization and manipulation of registration result(s), are provided. Examples of applications for such devices, systems, methods and storage mediums include imaging, evaluating and diagnosing biological objects, such as, but not limited to, lesions and tumors, and such devices, systems, methods and storage mediums may be used for radiotherapy applications (e.g., to determine whether to place seed(s) for radiotherapy).
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: October 17, 2023
    Assignee: Canon U.S.A., Inc.
    Inventor: Barret Daniels
  • Patent number: 11751827
    Abstract: This document relates to determining the configuration of a medical imaging system, in particular a configuration which defines a desired viewing direction of the medical imaging system onto a patient. First, a fluoroscopic image of at least a part of a patient is captured using the medical imaging system and the target central beam is set in the fluoroscopic image. Then a target line in space is determined which, when projected into the fluoroscopic image, coincides with the set target central beam. Then the configuration of the medical imaging system is determined such that the central beam of the medical imaging system coincides with the target line in space.
    Type: Grant
    Filed: September 24, 2019
    Date of Patent: September 12, 2023
    Assignee: Brainlab AG
    Inventors: Michael Bertram, Florian Glatz, Georg Christian
  • Patent number: 11684337
    Abstract: A tracking, and point-of-view-based imaging, device is configured for deriving a position of, and a direction from, a location at a distal tip of an elongated instrument, for performing coordinate system transformation in accordance with the position and direction, and for forming, from the location and based on a result of the transformation, a local view that moves with the tip. The device can keep, with the movement, a field of view of the local view fixed but the local view otherwise in synchrony with the position and the direction. From real-time ultrasound imaging, the local view and a more overall view that includes the tip but which does not move with said tip can be displayed. The distal tip can be that of a catheter and can be outfitted with a micromanipulator for surgery aided interactively by the combination of dynamic local and overall imaging.
    Type: Grant
    Filed: September 3, 2020
    Date of Patent: June 27, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Peter Waksman
  • Patent number: 11666431
    Abstract: Surgical devices and methods are provided for anchoring tissue to bone, and more particularly methods and devices are provided for preventing over-insertion of an expander into a sheath of a two-piece anchor. For example, a tendon anchoring system is provided with an anchor assembly and an inserter tool. The anchor assembly includes a sheath with a threaded lumen and a threaded expander screw configured to be threadably disposed within the sheath to cause the sheath to expand outward. The inserter tool includes an elongate outer shaft with a distal end configured to couple to a proximal end of the sheath, and an elongate inner shaft with a distal drive tip configured to engage a proximal end of the expander screw.
    Type: Grant
    Filed: August 21, 2019
    Date of Patent: June 6, 2023
    Assignee: Medos International Sarl
    Inventors: Mehmet Z. Sengun, Gregory R. Whittaker
  • Patent number: 11660144
    Abstract: A fiducial marker includes a fastener and a feedback component to provide a registration signal when engaged by a probe. The feedback component includes light-up cap, a conducting component, a magnetic component and an RFID tag. A cap for registering fiducial markers with robotic surgical systems includes a housing, a socket in the housing for coupling to a fastener, an access port in the housing, a switch disposed in the housing proximate the access port, and a sensory indicator device coupled to the switch, wherein the sensory indicator device produces a signal when activated through the access port to confirm marker contact. Methods of registering a fiducial marker fastener, such as with robotic surgical systems, include manipulating a probe to align with a signal-producing feedback component attached to or integrated with the fastener, and engaging the feedback component with the probe to activate a sensory feedback indicator.
    Type: Grant
    Filed: September 5, 2019
    Date of Patent: May 30, 2023
    Assignee: Zimmer Biomet CMF and Thoracic, LLC
    Inventors: Saddy Garcia, Florian Coiseur
  • Patent number: 11583353
    Abstract: A method of continuously registering a model of anatomic passageways to a patient space includes: collecting a set of measured points along a flexible catheter as the catheter is inserted into the passageways, the measured points based on a shape of the catheter; assigning each measured point to a respective subset of a plurality of subsets based upon a depth of each measured point within the passageways; comparing the plurality of subsets to identify a first optimal subset; registering the model to the patient space based on a set of model points and the first optimal subset; collecting additional measured points; updating the plurality of subsets by assigning each additional measured point to a respective subset; comparing, after the updating, the plurality of subsets to identify a second optimal subset; and registering the model to the patient space based on the set of model points and the second optimal subset.
    Type: Grant
    Filed: June 21, 2021
    Date of Patent: February 21, 2023
    Assignee: INTUITIVE SURGICAL OPERATIONS, INC.
    Inventors: Timothy D. Soper, Vincent Duindam
  • Patent number: 11559271
    Abstract: A method is for providing decision-supporting data. In an embodiment, the method includes receiving photon-counting computed tomography data relating to an examination region; determining a location of a thrombus in the examination region, based on the photon-counting computed tomography data received; generating the decision-supporting data, relating to at least one of the thrombus and a vascular wall in a region of the thrombus, based on the photon-counting computed tomography data received and the location of the thrombus determined; and providing the decision-supporting data generated.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: January 24, 2023
    Assignee: Siemens Healthcare GmbH
    Inventors: Bernd Hofmann, Sebastian Schmidt, Kerstin Mueller, Yufan Zhao
  • Patent number: 11523782
    Abstract: A high contrast instrument, such as a radiopaque portion, can be captured and/or viewed in an image that is acquired with an imaging system, such as with a fluoroscopic imaging system. A statistical model can be used to assist in identifying a possible or probable location of a target. A user may move the instrument coil to the statistically probable location of the target to, for example, perform a procedure or carry out a task.
    Type: Grant
    Filed: May 14, 2018
    Date of Patent: December 13, 2022
    Assignee: Medtronic, Inc.
    Inventors: Ryan P. Lahm, Ronald Alan Drake, Eric A. Schilling, Brian W. Schousek, Mark W. Shepler, Lester O. Stener
  • Patent number: 11331162
    Abstract: Provided herein are methods of documenting breast tissue in an area of interest in a subject in need thereof using automated breast ultrasound. The methods comprise using surface markers that can clearly identify the area of interest in a resulting 3-D image without introducing artifacts that obscure the tissue intended for examination.
    Type: Grant
    Filed: January 13, 2020
    Date of Patent: May 17, 2022
    Assignee: Imaging for Women, L.L.C.
    Inventor: Allison Zupon
  • Patent number: 11318297
    Abstract: A medical lead includes a main body having a length extending from a proximal end to a distal end, a longitudinal axis parallel to the length, and a proximal portion adjacent to the proximal end and a distal portion adjacent to the distal end; a plurality of electrodes defining an electrode region; and an imaging marker positioned between the electrode region and the proximal end and separated from the electrode region by a distance in an axial direction. The imaging marker may include one or more marker segments. The imaging marker may be disposed in a pocket of a sleeve at least partially surrounding the main body and comprising one or more pockets for receiving the imaging marker. The medical lead may be operatively connected to an implantable medical device.
    Type: Grant
    Filed: August 9, 2018
    Date of Patent: May 3, 2022
    Assignee: Medtronic, Inc.
    Inventors: Jiashu Li, Patrick Helm, Sean P. Skubitz, Ashutosh Chaturvedi
  • Patent number: 11291521
    Abstract: A surgery assisting device using augmented reality includes: a camera configured to record an affected area or a surgical site of a patient; wireless transmission equipment configured to receive and transmit an image recorded by the camera in real time; smart glasses configured to display the image transmitted by the wireless transmission equipment to a wearer; and an Augmented Reality (AR) server configured to add augmented reality to the image and provide the wearer with the augmented reality.
    Type: Grant
    Filed: November 8, 2019
    Date of Patent: April 5, 2022
    Inventor: Seung Joon Im
  • Patent number: 11264139
    Abstract: The present teaching relates to surgical procedure planning. In one example, at least one 3D object contained in a 3D volume is rendered on a display screen. The at least one 3D object includes a 3D object corresponding to an organ. First information related to a 3D pose of a surgical instrument positioned with respect to the at least one 3D object is received from a user. A 3D representation of the surgical instrument is rendered in the 3D volume based on the first information. Second information related to a setting of the surgical instrument is received from the user. A 3D treatment zone in the 3D volume with respect to the at least one 3D object is estimated based on the first and second information. The 3D treatment zone in the 3D volume is visualized on the display screen. Controls associated with the 3D representation of the surgical instrument and/or the 3D treatment zone are provided to facilitate the user to dynamically adjust the 3D treatment zone via the controls.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: March 1, 2022
    Assignee: EDDA TECHNOLOGY, INC.
    Inventors: Cheng-Chung Liang, Guo-Qing Wei, Li Fan, Jianzhong Qian, Xiaolan Zeng
  • Patent number: 11172996
    Abstract: Various embodiments of an apparatus, methods, systems and computer program products described herein are directed to Registration Engine. The Registration Engine tracks positions of a fiducial marker relative to positions of an Augmented Reality (AR) headset device worn by a user. The Registration Engine receives respective registration landmarks that correspond with locations of a physical region of a patient's anatomy and the tracked positions of the fiducial marker. The Registration Engine generates an AR display of medical data at the AR headset device in alignment with the physical region of a patient's anatomy that corresponds with the respective registration landmarks.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: November 16, 2021
    Assignee: Medivis, Inc.
    Inventors: Long Qian, Christopher Morley, Osamah Choudhry
  • Patent number: 11127193
    Abstract: A system for determining an approximate transformation between a first coordinate system and a second coordinate system, the system comprising a processing resource configured to: obtain an image captured by an image acquisition device of a mobile device; identify one or more synchronization objects within the image; determine first spatial dispositions of the synchronization objects with respect to a first coordinate-system origin of the first coordinate-system, the first coordinate system being a coordinate system of the mobile device; obtain information of second spatial dispositions of the synchronization objects with respect to a second coordinate-system origin of the second coordinate system; and determine, by employing an optimization scheme, utilizing the first spatial dispositions and the second spatial dispositions, the approximate transformation between the first coordinate-system and the second coordinate-system, the approximate transformation being usable by the mobile device for placing virtual
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: September 21, 2021
    Assignee: RESIGHT LTD.
    Inventors: Eran Segal, Ari Zigler, Omri Yaakov Stein
  • Patent number: 11103317
    Abstract: A medical robot system, including a robot coupled to an effectuator element with the robot configured for controlled movement and positioning. The system may include a transmitter configured to emit one or more signals, and the transmitter is coupled to an instrument coupled to the effectuator element. The system may further include a motor assembly coupled to the robot and a plurality of receivers configured to receive the one or more signals emitted by the transmitter. A control unit is coupled to the motor assembly and the plurality of receivers, and the control unit is configured to supply one or more instruction signals to the motor assembly.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: August 31, 2021
    Assignee: Globus Medical, Inc.
    Inventors: Neil R. Crawford, Nicholas Theodore, Mitchell A. Foster
  • Patent number: 11074685
    Abstract: A method for localizing an intracranial electrode in a subject's brain is provided. The intracranial electrode has at least one electrode contact. The method includes: acquiring a first brain image reconstructed from first image data acquired after electrode-implantation; acquiring a second brain image reconstructed from second image data acquired before the electrode-implantation; co-registering the first brain image and the second brain image to acquire spatial transformation parameters; extracting a first coordinate of the electrode contact from the first brain image; converting the first coordinate into a second coordinate in the second brain image by using the spatial transformation parameters; co-registering the second brain image and a universal brain atlas to define functional zones in the second brain image; and defining a corresponding functional zone where the second coordinate is located. Another alternative method and a system for localizing an intracranial electrode are also provided herein.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: July 27, 2021
    Assignee: NATIONAL YANG MING CHIAO TUNG UNIVERSITY
    Inventors: Syu-Jyun Peng, Cheng-Chia Lee, Chien-Chen Chou, Hsiang-Yu Yu
  • Patent number: 11051902
    Abstract: A system for planning and performing a repeat interventional procedure includes a registration device (116) and an image generation device (120) which map current targets in a reference image (104) for a first interventional procedure to at least one guidance image (112) acquired from a different imaging modality. Biopsy locations are recorded to the guidance images during the first interventional procedure and the biopsy locations are mapped to the reference image to provide a planning image for use in a subsequent interventional procedure on the patient. In a subsequent interventional procedure, the prior planning image (124) may be registered to a current reference image (126) and the prior biopsy locations and prior and current targets are mapped to a guidance image acquired from a different imaging modality. Biopsy locations are then mapped to the guidance image (115) and mapped back to the current reference image.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: July 6, 2021
    Assignees: KONINKLIJKE PHILIPS N.V., THE UNITED STATES OF AMERICA, as represented by the SECRETARY, DEPT OF HEALTH AND HUMAN SERVICES
    Inventors: Jochen Kruecker, Pingkun Yan, Amir Mohammad Tahmasebi Maraghoosh, Peter A Pinto, Bradford Johns Wood
  • Patent number: 11042971
    Abstract: Methods, systems, and apparatus, including computer programs encoded on computer storage media, for medical imaging with distortion correction. One example includes obtaining distorted image data of a subject brain, the distorted image data comprising a time series of three-dimensional image tensors generated at least in part from an echo planar imaging session of the subject brain. A derived three-dimensional tensor is derived from the distorted image data. A non-rigid alignment function to non-rigidly align the derived three-dimensional tensor to a reference tensor is determined, producing a non-rigidly aligned derived 3D tensor. A rigid alignment function to rigidly align the non-rigidly aligned derived 3D tensor to the reference tensor is determined. Distortion-corrected image data is created by applying the rigid alignment function and the non-rigid alignment function to the time series of three-dimensional image tensors.
    Type: Grant
    Filed: August 13, 2020
    Date of Patent: June 22, 2021
    Assignee: Omniscient Neurotechnology Pty Limited
    Inventors: Michael Edward Sughrue, Stephane Philippe Doyen, Peter James Nicholas
  • Patent number: 11037030
    Abstract: A method for computing classifications of raw tomographic data includes: supplying the raw tomographic data to a sinogram-convolutional neural network including blocks, at least one of the blocks being configured to perform a convolution of the raw tomographic data in Radon space with a convolutional kernel by: slicing the raw tomographic data into a plurality of one-dimensional tomographic data slices along an angle dimension of the raw tomographic data; slicing the convolutional kernel into a plurality of one-dimensional kernel slices along the angle dimension of the convolutional kernel; for each angle, computing a one-dimensional convolution between: a corresponding one of the one-dimensional tomographic data slices at the angle; and a corresponding one of the one-dimensional kernel slices at the angle; and collecting the one-dimensional convolutions at the angles; computing a plurality of features from the convolution; and computing the classifications of the raw tomographic data based on the features.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: June 15, 2021
    Assignee: HRL Laboratories, LLC
    Inventor: Soheil Kolouri
  • Patent number: 10994451
    Abstract: A permanent or temporary marker is embedded within a hydrogel plug used in a biopsy procedure to indicate the location of a suspicious lesion so that the marker may be found in a subsequent surgical procedure. A combination of at least one permanent and at least one temporary marker may be used. Inserts of differing sizes and shapes may also be placed into the hydrogel plugs during their manufacturing process and removed from the plugs after the plugs have cured so that air-filled cavities are left in the plug. These cavities are temporary but may be used to augment location of a permanent marker.
    Type: Grant
    Filed: February 19, 2019
    Date of Patent: May 4, 2021
    Assignee: Devicor Medical Products, Inc.
    Inventors: John S. Fisher, Frederick Ahari
  • Patent number: 10921395
    Abstract: A system and method for providing virtual real-time MRI-guidance for a biopsy outside of a conventional MRI scanner is described. MR images and ultrasound images of a region of a patient's body are simultaneously acquired during a pre-biopsy procedure. Respiratory states that the patient may experience during the biopsy are then determined from the acquired ultrasound images, and each respiratory state is associated with corresponding MR images. The MR images are indexed with their corresponding respiratory state. Ultrasound images are then acquired of the patient during a biopsy procedure. The respiratory state of the patient is determined from the ultrasound images, and the corresponding indexed MR images are displayed.
    Type: Grant
    Filed: January 12, 2018
    Date of Patent: February 16, 2021
    Assignee: GE PRECISION HEALTHCARE LLC
    Inventors: Thomas Kwok-Fah Foo, Jhimli Mitra, Bo Wang, Lowell Scott Smith, David Martin Mills, Warren Lee, James Hartman Holmes, Bryan Bednarz, Roberta Marie Strigel
  • Patent number: 10842379
    Abstract: A system and method for multi-modality fusion for 3D printing of a patient-specific organ model is disclosed. A plurality of medical images of a target organ of a patient from different medical imaging modalities are fused. A holistic mesh model of the target organ is generated by segmenting the target organ in the fused medical images from the different medical imaging modalities. One or more spatially varying physiological parameter is estimated from the fused medical images and the estimated one or more spatially varying physiological parameter is mapped to the holistic mesh model of the target organ. The holistic mesh model of the target organ is 3D printed including a representation of the estimated one or more spatially varying physiological parameter mapped to the holistic mesh model. The estimated one or more spatially varying physiological parameter can be represented in the 3D printed model using a spatially material property (e.g.
    Type: Grant
    Filed: January 26, 2017
    Date of Patent: November 24, 2020
    Assignee: Siemens Healthcare GmbH
    Inventors: Tommaso Mansi, Helene Houle, Sasa Grbic, Andrzej Milkowski
  • Patent number: 10828125
    Abstract: A surgical imaging system is described. The system includes first and second optical assemblies. Each optical assembly defines a respective optical axis, and each includes a respective set of one or more optics for adjusting field-of-view (FOV) and focus and a respective camera for capturing an image. The system includes a controller for controlling the optical assemblies and for switching the surgical imaging system between a coupled configuration and an uncoupled configuration. In the coupled configuration, the first optical assemblies are controlled to adjust the respective sets of optics and/or the respective optical axes in dependence on each other. In the uncoupled configuration, the optical assemblies are controlled to adjust the respective sets of optics, and the respective optical axes independently of each other.
    Type: Grant
    Filed: November 3, 2015
    Date of Patent: November 10, 2020
    Assignee: Synaptive Medical (Barbados) Inc.
    Inventors: Michael Frank Gunter Wood, Cameron Anthony Piron, Tammy Kee-Wai Lee, Kamyar Abhari, Kai Michael Hynna
  • Patent number: 10786309
    Abstract: The invention relates to a registration system (13) for registering an optical shape system to an imaging system with an imaging device (2) like a radiation C-arm device with a tracking device (4) like an optical shape sensing tracking device. One or more optical cameras (27) are used to detect position information of a tracked object to register the shape coordinate system with that of the imaging system. The optical cameras are pre-calibrated with the imaging system, so that the detected position information in the camera system can directly be translated to the imaging system.
    Type: Grant
    Filed: December 2, 2014
    Date of Patent: September 29, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventor: Ahmet Ekin
  • Patent number: 10643371
    Abstract: A system and method for planning surgical procedure including a treatment zone setting view presenting at least one slice of a 3D reconstruction generated from CT image data including a target. The treatment zone setting view presenting a treatment zone marker defining a location and a size of a treatment zone and configured to adjust the treatment zone marker in response to a received user input. The system and method further including a volumetric view presenting a 3D volume derived from the 3D reconstruction and a 3D representation of the treatment zone marker relative to structures depicted in the 3D volume.
    Type: Grant
    Filed: August 10, 2015
    Date of Patent: May 5, 2020
    Assignee: COVIDIEN LP
    Inventors: Jeetendra Bharadwaj, Kevin J. Frank, Darren G. Girotto, Benjamin M. Corum
  • Patent number: 10624540
    Abstract: An operating microscope including an optical unit for forming an image of an object plane in oculars of the microscope, an optoelectronic image receiver coupled to the microscope and optics to form images, of objects placed in a region between a front objective of the microscope and an object plane of the microscope, on the optoelectronic image receiver. The microscope has a magnification factor of the optics to form images, and a system to detect optical markings forming a markings pattern placed on a surgical instrument or an object placed in the region between the front objective of the microscope and the object plane of the microscope. The system calculates a geometrical position and orientation of the markings pattern in relation to the optoelectronic image receiver, relative to the microscope.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: April 21, 2020
    Assignee: Moeller-Wedel GmbH
    Inventors: Martin Schmidt, Jochen Koetke, Peter Schalt, Stefan Oelkers, Rolf-Rainer Grigat, Thomas Hoell
  • Patent number: 10610841
    Abstract: A method and system are used to enhance a marker material to include a plurality of air bubbles. The method of manufacturing a marker includes enhancing a marker material to include a plurality of air bubbles using at least a first EFD and a second EFD. The method may include cycling repeatedly through a transfer process between a first container and a second container. A system for enhancing a marker material includes a transfer apparatus configured to receive a marker material and a selected amount of air. The system comprises a first EFD coupled to a first end of the transfer apparatus and a second EFD coupled to a second end of the transfer apparatus.
    Type: Grant
    Filed: June 28, 2017
    Date of Patent: April 7, 2020
    Assignee: Devicor Medical Products, Inc.
    Inventors: Timothy Zimmer, Michelle Louise Johnson, Stephen D. Stallard
  • Patent number: 10575733
    Abstract: Methods for performing orthopaedic surgical procedures including generating scan data from the intra-operatives scans and comparing the scan data to a surgical plan are disclosed. The scan data and other feedback data are used to validate the position and orientation of orthopaedic prosthetic component implanted in a body of the patient.
    Type: Grant
    Filed: January 25, 2019
    Date of Patent: March 3, 2020
    Assignee: DePuy Synthes Products, Inc.
    Inventor: Ryan C. Keefer
  • Patent number: 10539675
    Abstract: In an embodiment, a system and method are provided for determining position and orientation of an optical delivery unit relative to an acoustic receiving unit, in the field of opto-acoustic imaging, wherein the optical delivery unit comprises a first fiducial marker site configured to emit acoustic responses and a second fiducial marker site configured to emit acoustic responses. A plurality of acoustic signals from a volume of a subject are sampled and recorded, each of the plurality of acoustic signals being collected at a different data collection position relative to a coordinate reference frame. The system is configured to identify in each of the plurality of acoustic signals a response of a first fiducial marker and a response of a second fiducial marker. Each identified response indicates a separation between a fiducial marker site and a data collection position of an acoustic signal.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: January 21, 2020
    Assignee: Seno Medical Instruments, Inc.
    Inventor: Jason Zalev
  • Patent number: 10524812
    Abstract: A method for locating and visualizing a target (C) in relation to a focal point (F2), in a mammal, particularly a human body, including the steps of forming an ultrasound probe mobile in space, mechanically independent of a treatment system and located by a remote locating system, ensuring simultaneous recording firstly of an ultrasound image in which the image of the target appears, and secondly of the position of the ultrasound probe, in the recorded ultrasound image, selecting the position of the image of the target to determine the virtual position of the target (C), simultaneously determining firstly the position of the focal point (F2) by the remote locating system, and secondly the position of the members displacing the target and/or treatment system, and calculating the displacement values for the displacing members, to cause the virtual position of the target (C) to coincide with the focal point (F2).
    Type: Grant
    Filed: December 23, 2010
    Date of Patent: January 7, 2020
    Assignee: EDAP TMS FRANCE
    Inventors: Andre Peyrard, Claire Vurpillot, Rene Chatre
  • Patent number: 10431001
    Abstract: The success of percutaneous radiofrequency ablation mainly depends on the accuracy of the needle insertion, making it possible to destroy the whole tumor, while avoiding damages on other organs and minimizing risks of a local recurrence. This invention presents a simulated 3D environment for user to interactively place a treatment probe to a target position.
    Type: Grant
    Filed: November 21, 2008
    Date of Patent: October 1, 2019
    Assignee: EDDA TECHNOLOGY, INC.
    Inventors: Cheng-Chung Liang, Guo-Qing Wei, Li Fan, Jianzhong Qian, Hong Chen, Feng Ma, Xiaolan Zeng
  • Patent number: 10426554
    Abstract: A tracking and navigation system is provided. The system includes an imaging or treatment device, a tracker device, and a fiducial marker. At least part of the imaging or treatment device is movable relative to a patient. The tracker device is mounted on the imaging or treatment device and is movable therewith relative to the patient. The fiducial marker may be fixed relative to the patient to define a patient coordinate system. The fiducial marker is detectable by the tracker device to substantially maintain registration between the tracker device and the patient coordinate system. A tracking and navigation kit including the tracker device and at least one fiducial marker may also be provided, for example, for retrofitting to existing imaging or treatment devices.
    Type: Grant
    Filed: April 30, 2012
    Date of Patent: October 1, 2019
    Assignee: The Johns Hopkins University
    Inventors: Jeffrey H. Siewerdsen, Yoshito Otake, Russell H. Taylor
  • Patent number: 10426560
    Abstract: Robotic system and method for positioning an energy applicator extending from a surgical instrument. The robotic system includes a surgical manipulator operable in a manual mode or a semi-autonomous mode. The surgical manipulator moves the energy applicator along a tool path in the semi-autonomous mode and reorients the surgical instrument.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: October 1, 2019
    Assignee: Stryker Corporation
    Inventors: David Gene Bowling, John Michael Stuart, Joel N. Beer
  • Patent number: 10413185
    Abstract: Methods and system for atrial fibrillation ablations utilizing cardiac mapping based on medical image(s). The method and system also adapted for any balloon based catheters including cryoballoon catheter, laser balloon catheter, or “hot balloon” catheter, as well as circular catheters. The methods and system includes overlaying of two or more images on top of each other (where the images are of various types) and aligning the images, where the transparency between the images can be adjusted as an aid for optimal placement of the balloon based catheters or circular catheters. 3D volumetricTags and markers are also placed on 3D images such as CT and MRI images which are indicative of where the tissue has been ablated. The method and system also comprises the ability to monitor esophageal temperature, and to activate alarms and/or energy delivery interrupt based on pre-determined esophageal temperature parameters.
    Type: Grant
    Filed: November 20, 2017
    Date of Patent: September 17, 2019
    Assignee: AMERICAN MEDICAL TECHNOLOGIES, LLC
    Inventors: Birinder R. Boveja, Angely Widhany
  • Patent number: 10376712
    Abstract: A real-time applicator position monitoring system (RAPS) measures brachytherapy applicator displacement in real-time by computing the relative displacement between two infrared reflective targets, one attached to the applicator and the other to the patient's skin. In an aspect, RAPS can be used with any brachytherapy application. RAPS measures the applicator motion during HDR brachytherapy treatment, as well as during the transfer of the patient from the imaging room (e.g., where the CT and MR scanners are located) to the HDR BT operating/treatment room.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: August 13, 2019
    Assignee: University of Iowa Research Foundation
    Inventors: Junyi Xia, Yusung Kim, Timothy J. Waldron
  • Patent number: 10376179
    Abstract: A system employs an interventional tool (30), ultrasound imaging system and a multi-planar reformatting module (40). The interventional tool (30) has one or more image tracking points (31). The ultrasound imaging system includes an ultrasound probe (20) operable for generating an ultrasound volume image (22) of a portion or an entirety of the interventional tool (30) within an anatomical region. The multi-planar reformatting imaging module (40) generates two or more multi- planar reformatting images (41) of the interventional tool (30) within the anatomical region. A generation of the two multi-planar reformatting images (41) includes an identification of each image tracking point (31) within the ultrasound volume image (22), and a utilization of each identified image tracking point (31) as an origin of the multi-planar reformatting images (41).
    Type: Grant
    Filed: April 19, 2012
    Date of Patent: August 13, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Vijay Parthasarathy, Ameet Kumar Jain, Charles Ray Hatt, III, Amish N. Raval
  • Patent number: 10347380
    Abstract: Described herein are methods, systems and devices for image-guided, computer-assisted surgical procedures, in particular for intra-operative registration of anatomical structures. Embodiments of the invention may enable a user to register the surface of an anatomical structure intra-operatively in an interactive, computer-guided process. The user may send information about acquired data points to the computer, and the computer may evaluate the aggregate of data points, optionally provide instructions to the user for acquisition of additional data points, and signal to the user when sufficient data points have been acquired for registration of the surface of the anatomical structure.
    Type: Grant
    Filed: March 11, 2014
    Date of Patent: July 9, 2019
    Assignee: THINK SURGICAL, INC.
    Inventors: Denise A. Miller, Rose A. Cipriano, Li Lu
  • Patent number: 10335124
    Abstract: A marker delivery device includes a cannula with a first end, a second end, a marker exit near the second end, a handle into which the cannula extends or to which the cannula is attached, the cannula being capable of receiving a plunger and rod that are operable to deploy a marker from the marker exit, the marker delivery device further including a tapered adaptor portion attached to or surrounding the cannula and abutting the handle. The tapered adaptor portion is configured to engage a plurality of different sleeves for differing biopsy devices. Various aspects offer improved ease of removal from commercially available biopsy devices due to its “pinch release” feature. Various aspects of the device allow use with multiple commercially available biopsy devices so as to ensure proper positioning of the devices for marker deployment.
    Type: Grant
    Filed: February 28, 2017
    Date of Patent: July 2, 2019
    Assignee: Devicor Medical Products, Inc.
    Inventors: Andrew Robinson, Emmanuel Tanghal
  • Patent number: 10323183
    Abstract: This invention provides a groundbreaking approach to PLNPs and their preparation. In particular, the synthetic methodology disclosed herein fundamentally differs from the traditional solid-state annealing reactions that require extreme and harsh reaction conditions. In one unique aspect of the invention, a simple, one-step mesoporous template method utilizing mesoporous silica nanoparticles (MSNs) is disclosed that affords in vivo rechargeable NIR-emitting mesoporous PLNPs with uniform size and morphology. In another unique aspect of the invention, the novel synthetic approach is based on aqueous-phase chemical reactions conducted in mild conditions, resulting in uniform and homogeneous PLNPs with desired size control (e.g., sub-10 nm).
    Type: Grant
    Filed: February 29, 2016
    Date of Patent: June 18, 2019
    Assignee: University of Massachusetts
    Inventors: Gang Han, Zhanjun Li
  • Patent number: 10206579
    Abstract: Methods for performing orthopedic surgical procedures including generating scan data from the intra-operatives scans and comparing the scan data to a surgical plan are disclosed. The scan data and other feedback data are used to validate the position and orientation of orthopedic prosthetic component implanted in a body of the patient.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: February 19, 2019
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventor: Ryan C. Keefer
  • Patent number: 10127645
    Abstract: An embodiment of the present disclosure discloses a method and a device of correcting a single-molecule image, the method includes: acquiring the first target simplified matrix corresponding to the first image according to the intensity matrix corresponding to each of pixels in the first image, and acquiring the second target simplified matrix corresponding to the second image according to the intensity matrix corresponding to each of the pixels in the second image; the two-dimensional DFT is performed to the first target simplified matrix and the second target simplified matrix respectively to acquire the first Fourier matrix corresponding to the first target simplified matrix and the second Fourier matrix corresponding to the second target simplified matrix; the method of correcting a single-molecule image acquire the offset of the second image with respect to the first image according to the first Fourier matrix and the second Fourier matrix; and correcting the second image according to the offset.
    Type: Grant
    Filed: August 11, 2016
    Date of Patent: November 13, 2018
    Assignee: DIRECT GENOMICS CO., LTD
    Inventors: Liangjin Ge, Jianming Zeng, Qin Yan
  • Patent number: 10085645
    Abstract: Methods for performing orthopaedic surgical procedures using a handheld scanner are disclosed. The methods include, generally, performing one or more intra-operative scans using a handheld scanner, generating scan data from the intra-operatives scans, and comparing the scan data to a surgical plan. The scan data and other feedback data are used to validate the position and orientation of orthopaedic prosthetic component implanted in a body of the patient.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: October 2, 2018
    Assignee: DEPUY SYNTHES PRODUCTS, INC.
    Inventor: Ryan C. Keefer
  • Patent number: 10070929
    Abstract: A system of this invention is directed to a surgical operation support system that supports determination of an appropriate disposition of a bone in a living body during surgery.
    Type: Grant
    Filed: June 11, 2014
    Date of Patent: September 11, 2018
    Inventor: Atsushi Tanji
  • Patent number: 9956041
    Abstract: A robotic device for performing intracranial procedures, comprising a baseplate for mounting on the subject's skull and a rotatable base element rotating on the baseplate. The rotatable base element has a central opening through which a cannulated needle can protrude such that it can rotate around an axis perpendicular to the baseplate. This cannulated needle is robotically controlled to provide motion into and out of the subject's skull. A flexible needle is disposed coaxially within the cannulated needle, and it is controlled to move into and out of a non-axial aperture in the distal part of the cannulated needle. Coordinated control of the insertion motion of the cannulated and flexible needles, and rotation of the combined cannulated/flexible needle assembly enables access to be obtained to a volume of a region of the brain having lateral dimensions substantially larger than the width of the cannulated needle.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: May 1, 2018
    Assignee: TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD.
    Inventors: David Zarrouk, Moshe Shoham, Menashe Zaaroor, Hadas Ziso
  • Patent number: 9824497
    Abstract: The present disclosure is generally directed to an information processing apparatus comprising at least one processor configured to execute instructions to generate a superimposition parameter corresponding to superimposing virtual information on a real space based on a spatial position of a marker projected on the real space by an input apparatus, and cause a display section to display the virtual information superimposed on the real space according to the spatial position relationship while the marker is detectable and continue the display of the virtual information superimposed on the real space after the marker is undetectable according to a last detected spatial position of the marker.
    Type: Grant
    Filed: February 20, 2013
    Date of Patent: November 21, 2017
    Assignee: SONY CORPORATION
    Inventors: Tetsuro Goto, Masatoshi Ueno, Kenichi Kabasawa, Toshiyuki Nakagawa, Daisuke Kawakami, Shinobu Kuriya, Tsubasa Tsukahara, Hisako Sugano