Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
January 16, 2003
Date of Patent:
October 19, 2004
Assignee:
Applera Corporation
Inventors:
Jane Ye, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
September 25, 2003
Date of Patent:
October 5, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Ming-Hui Wei, Karen Ketchum, Gennady Merkulov, Ellen M Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
July 22, 2002
Date of Patent:
October 5, 2004
Assignee:
Applera Corporation
Inventors:
Fangcheng Gong, Ming-Hui Wei, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the dehydrogenase polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the dehydrogenase polypeptides, and methods of identifying modulators of the dehydrogenase polypeptides.
Type:
Grant
Filed:
April 9, 2002
Date of Patent:
September 28, 2004
Assignee:
Applera Corporation
Inventors:
Fangcheng Gong, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
Type:
Grant
Filed:
February 21, 2003
Date of Patent:
September 7, 2004
Assignee:
Applera Corporation
Inventors:
Ellen M. Beasley, Gennady V. Merkulov, Valentina Di Francesco
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
January 10, 2003
Date of Patent:
August 24, 2004
Assignee:
Applera Corporation
Inventors:
Jiayin Li, Karl Guegler, Ellen M. Beasley, Karen A. Ketchum, Valentina Di Francesco
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
Type:
Grant
Filed:
April 9, 2002
Date of Patent:
August 10, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Karen A. Ketchum, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the nuclear hormone receptor peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the nuclear hormone receptor peptides, and methods of identifying modulators of the nuclear hormone receptor peptides.
Type:
Grant
Filed:
October 19, 2000
Date of Patent:
June 29, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Jane Ye, Chunhua Yan, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
July 31, 2002
Date of Patent:
June 22, 2004
Assignee:
Applera Corporation
Inventors:
Jane Abu-Threideh, Fangcheng Gong, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the secreted peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides.
Type:
Grant
Filed:
October 21, 2002
Date of Patent:
June 22, 2004
Assignee:
Applera Corporation
Inventors:
Steven I. Ladunga, Eugene Spier, Maureen Higgins, Simon Greenberg, Yu Wang
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
Type:
Grant
Filed:
March 14, 2001
Date of Patent:
June 1, 2004
Assignee:
Applera Corporation
Inventors:
Weiniu Gan, Jane Ye, Valentina Di Francesco, Ellen M Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
May 1, 2002
Date of Patent:
May 25, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Karen A. Ketchum, Valentina Difrancesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the secreted peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the secreted peptides, and methods of identifying modulators of the secreted peptides.
Type:
Grant
Filed:
April 25, 2001
Date of Patent:
May 25, 2004
Assignee:
Applera Corporation
Inventors:
Ellen M Beasley, Ming-Hui Wei, Fangcheng Gong, Steven I Ladunga, Maureen E Higgins
Abstract: The present invention provides amino acid sequences of human lanosterol synthase proteins and nucleic acid sequences encoding these lanosterol synthase proteins. The present invention provides isolated lanosterol synthase proteins and encoding nucleic acid molecules, vectors and host cells containing these nucleic acid molecules, and processes for producing the lanosterol synthase proteins.
Type:
Grant
Filed:
March 23, 2001
Date of Patent:
May 18, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Chunhua Yan, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
January 10, 2003
Date of Patent:
May 11, 2004
Assignee:
Applera Corporation
Inventors:
Chunhua Yan, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of polypeptides that are encoded by genes within the human genome, the Ras-like protein polypeptides of the present invention. The present invention specifically provides isolated polypeptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the Ras-like protein polypeptides, and methods of identifying modulators of the Ras-like protein polypeptides.
Type:
Grant
Filed:
February 21, 2001
Date of Patent:
May 11, 2004
Assignee:
Applera Corporation
Inventors:
Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the drug-metabolizing enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the drug-metabolizing enzyme peptides, and methods of identifying modulators of the drug-metabolizing enzyme peptides.
Type:
Grant
Filed:
June 6, 2002
Date of Patent:
May 4, 2004
Assignee:
Applera Corporation
Inventors:
Karl Guegler, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the kinase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the kinase peptides, and methods of identifying modulators of the kinase peptides.
Type:
Grant
Filed:
August 21, 2002
Date of Patent:
May 4, 2004
Assignee:
Applera Genomics
Inventors:
Chunhua Yan, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the enzyme peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the enzyme peptides, and methods of identifying modulators of the enzyme peptides.
Type:
Grant
Filed:
August 28, 2002
Date of Patent:
April 20, 2004
Assignee:
Applera Corporation
Inventors:
Ming-Hui Wei, Jane Ye, Karen A. Ketchum, Valentina Di Francesco, Ellen M. Beasley
Abstract: The present invention provides amino acid sequences of peptides that are encoded by genes within the human genome, the phosphatase peptides of the present invention. The present invention specifically provides isolated peptide and nucleic acid molecules, methods of identifying orthologs and paralogs of the phosphatase peptides, and methods of identifying modulators of the phosphatase peptides.
Type:
Grant
Filed:
April 2, 2001
Date of Patent:
April 20, 2004
Assignee:
Applera Corporation
Inventors:
Ellen M. Beasley, Marion Webster, Valentina Di Francesco, Ming-Hui Wei