Patents Represented by Attorney, Agent or Law Firm Elias J Lambiris
  • Patent number: 6264946
    Abstract: The present invention relates to the combined use, simultaneous or sequential, of one or more xylanolytic enzymes of Type I with one or more xylanolytic enzymes of Type II in animal feed. It also relates to animal feed and animal feed additives comprising such combination of xylanolytic enzymes.
    Type: Grant
    Filed: October 9, 1998
    Date of Patent: July 24, 2001
    Assignee: Novozymes A/S
    Inventors: Anette Müllertz, Lene Beck Jensen, Betina Kastbjerg Jensen
  • Patent number: 6261828
    Abstract: A one-step process for combined desizing and “stone-washing” of dyed denim, wherein the denim is treated with an amylolytic enzyme in combination with a first abrading monocomponent endoglucanase and a second streak-reducing monocomponent endoglucanase.
    Type: Grant
    Filed: April 29, 1998
    Date of Patent: July 17, 2001
    Assignee: Novo Nordisk A/S
    Inventor: Henrik Lund
  • Patent number: 6255084
    Abstract: The invention relates to an isolated thermostable glucoamylase derived from Talaromyces emersonii suitable for starch conversion processes.
    Type: Grant
    Filed: November 24, 1998
    Date of Patent: July 3, 2001
    Assignee: Novozymes A/S
    Inventors: Bjarne Rønfeldt Nielsen, Ruby Ilum Nielsen, Jan Lehmbeck
  • Patent number: 6254856
    Abstract: The present invention relates to oral care compositions and products comprising a dextranase and a mutanase, and optionally other enzymes.
    Type: Grant
    Filed: October 2, 1998
    Date of Patent: July 3, 2001
    Assignee: Novo Nordisk, A/S
    Inventor: Rie Tsuchiya
  • Patent number: 6245901
    Abstract: The present invention relates to polypeptide-polymer conjugates having added and/or removed one or more attachment groups for coupling polymeric molecules on the surface of the polypeptide structure, a method for preparing polypeptide-polymer conjugates of the invention, the use of said conjugated for reducing the immunogenicity and allergenicity and compositions comprising said conjugate.
    Type: Grant
    Filed: February 17, 1998
    Date of Patent: June 12, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Claus von der Osten, Arne Agerlin Olsen, Erwin Ludo Roggen
  • Patent number: 6242237
    Abstract: The present invention relates to an enzyme with galactanase activity, a DNA construct encoding the enzyme with galactanase activity, a method of producing the enzyme, an enzyme composition comprising the enzyme with galactanase activity, and the use of the galactanase enzyme and enzyme composition for a number of industrial applications.
    Type: Grant
    Filed: August 21, 1998
    Date of Patent: June 5, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Lene Venke Kofod, Markus Sakari Kauppinen, Lene Nonboe Andersen, Ib Groth Clausen, Anette Müllertz
  • Patent number: 6232101
    Abstract: A method for causing gelling or increase of viscosity of an aqueous medium containing a gellable polymeric material having substituents with phenolic hydroxy groups comprises adding an oxidase, particularly a laccase, to the aqueous medium.
    Type: Grant
    Filed: October 28, 1996
    Date of Patent: May 15, 2001
    Assignee: Novozymes A/S Patents
    Inventors: Gitte Budolfsen, Hans Peter Heldt-Hansen
  • Patent number: 6231621
    Abstract: The invention relates to substrates which develops color on oxidation of general formula (I). The invention also relates to the use of said substrates for dyeing, e.g. keratinous fibers, in particular hair, dyeing textiles, a dyeing composition and a method for dyeing keratinous fibers.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: May 15, 2001
    Assignee: Novozymes A/S
    Inventors: Niels Henrik Sørensen, Ole Kirk, Rikke Lolck, Torben Desler
  • Patent number: 6228630
    Abstract: An enzyme preparation comprising (a) first enzyme with xylanase activity and (b) a second enzyme having cellulotytic, xylanolytic or pectinolytic activity and are supported by the specification.
    Type: Grant
    Filed: June 22, 2000
    Date of Patent: May 8, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Lene Venke Kofod, MArkus Sakari Kauppinen, Stephan Christgau, Hans Peter Heldt-Hansen, Henrik Dalbøge, Lene Nonboe Andersen, Joan Qi Si, Tina Sejersgåard Jacobsen, Niels Munk, Anette Müllertz
  • Patent number: 6221821
    Abstract: Variants of a parent vanadium-containing haloperoxidase, which variant has haloperoxidase activity and an altered pH optimum and comprises a mutation in a position corresponding to at least one of the following positions: R490A, L, I, Q, M, E, D; A399G; F397N, Y, E, Q; P395A, S; R360A, L, I, Q, M, E, D; K353Q, M; S402A, T, V, S; D292L; A501S; W350F, Y; V495A, T, V, S; K394 A, L, I, Q, M, E, D; wherein the parent haloperoxidase has the amino acid sequence given in SEQ ID No. 1, or the parent haloperoxidase has an amino acid sequence which is at least 80% homologous to SEQ ID No. 1.
    Type: Grant
    Filed: March 18, 1999
    Date of Patent: April 24, 2001
    Assignee: Novozymes A/S Patents
    Inventors: Allan Svendsen, Louise Jørgensen
  • Patent number: 6218170
    Abstract: The present invention relates to laccase mutants with increased oxidation potential and/or changed pH optimum and/or altered mediator pathway and/or altered O2/OH− pathway.
    Type: Grant
    Filed: March 6, 2000
    Date of Patent: April 17, 2001
    Assignee: Novo Nordisk A/S
    Inventor: Allan Svendsen
  • Patent number: 6207149
    Abstract: The present invention relates to an oral care composition comprising a Starch Binding Domain and further ingredients conventionally used in oral care compositions, oral care products, and the use of SBDs for oral care purposes.
    Type: Grant
    Filed: March 25, 1999
    Date of Patent: March 27, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Claus Crone Fuglsang, Rie Tsuchiya
  • Patent number: 6204232
    Abstract: The invention relates to a variant of a parent Termamyl-like &agr;-amylase, which exhibits an alteration in at least one of the following properties relative to said parent &agr;-amylase: i) improved pH stability at a pH from 8 to 10.5; and/or ii) improved Ca2+ stability at pH 8 to 10.5, and/or iii) increased specific activity at temperatures from 10 to 60° C.
    Type: Grant
    Filed: October 30, 1998
    Date of Patent: March 20, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Torben Vedel Borchert, Allan Svendsen, Carsten Andersen, Bjarne Nielsen, Torben Lauesgaard Nissen, Søren Kjærulff
  • Patent number: 6200792
    Abstract: The present invention relates to an enzyme exhibiting aminopeptidase activity, a method for producing said enzyme, an enzyme preparation containing said enzyme exhibiting aminopeptidase activity, and use of said enzyme for various industrial purposes.
    Type: Grant
    Filed: May 30, 2000
    Date of Patent: March 13, 2001
    Assignee: Novo Nordisk-A/S Novo Alle
    Inventors: Markus Sakari Kauppinen, Joan Qi Si, Tina Spendler, Claus Dambmann, Torben Halkier, Peter Rahbek Østergaard, Shamkant Anant Patkar, Kim Hansen
  • Patent number: 6201110
    Abstract: The invention relates to modified polypeptides with reduced respiratory allergenicity comprising a parent polypeptide with a molecular weight from between 10 kDa and 100 kDa conjugated to a polymer with a molecular weight (Mr) in the range of 1 kDa and 60 kDa. The modified polypeptide are produced using a process including the step of conjugating from 1 to 30 polymer molecules with the parent polypeptide. Further the invention relates to compositions comprising said polypeptides and further ingredients normally used in e.g. detergents, including dishwashing detergents and soap bars, household article, agrochemicals, personal care products, cosmetics, toiletries, oral and dermal pharmaceuticals, composition for treating textiles, and compositions used for manufacturing food and feed. Finally the invention is directed to uses of polypeptides with reduced allergenicity or compositions thereof for reducing the allergenicity of products for a vast number of industrial applications.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: March 13, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Arne Agerlin Olsen, Lars Bo Hansen, Thomas Christian Beck
  • Patent number: 6197565
    Abstract: The invention relates to a variant of a parent Termamyl-like &agr;-amylase, comprising mutations in two, three, four, five or six regions/positions. The variants have increased stability at high temperatures (relative to the parent). The invention also relates to a DNA construct comprising a DNA sequence encoding an &agr;-amylase variant of the invention, a recombinant expression vector which carries a DNA construct of the invention, a cell which is transformed with a DNA construct of the invention, the use of an &agr;-amylase variant of the invention for washing and/or dishwashing, textile desizing, starch liquefaction, a detergent additive comprising an &agr;-amylase variant of the invention, a manual or automatic dishwashing detergent composition comprising an &agr;-amylase variant of the invention, a method for generating a variant of a parent Termamyl-like &agr;-amylase, which variant exhibits increased.
    Type: Grant
    Filed: November 16, 1998
    Date of Patent: March 6, 2001
    Assignees: Novo-Nordisk A/S, Novo Alle
    Inventors: Allan Svendsen, Sóeren Kjaerulff, Henrik Bisgaard-Frantzen, Carsten Andersen
  • Patent number: 6197567
    Abstract: Enzymes produced by mutating the genes for a number of subtilisin proteases and expressing the mutated genes in suitable hosts are presented. The enzyme exhibit improved wash performance in comparison to their wild type parent enzymes. The enzymes are well-suited for use in detergent compositions.
    Type: Grant
    Filed: March 12, 1997
    Date of Patent: March 6, 2001
    Assignees: Novo Nordisk A/S, Unilever PLC
    Inventors: Dorrit Aaslyng, Sven Branner, Sven Hastrup, Leif Nørskov-Lauritsen, Ole Hvilsted Olsen, Merete Simonsen, Eric Casteleijn, Maarten Robert Egmond, Johan Haverkamp, John David Marugg, Arnoldus Theodorus Anthonius Mooren
  • Patent number: 6194183
    Abstract: The invention relates to a method of identifying enzymes suitable for use in detergents, especially the selection of specific enzyme variants among a large number of such variants created through random mutagenesis.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: February 27, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Peter Markvardsen, Mads Eskelund Bjornvad, Frank Mikkelsen, Borge Diderichsen
  • Patent number: 6190900
    Abstract: The present invention relates to enzymes produced by mutating the genes for a number of subtilases and expressing the mutated genes in suitable hosts are presented. The enzymes exhibit improved stability and/or improved wash performance in any detergent in comparison to their wild type parent enzymes. The enzymes are well-suited for use in any detergent and for some in especially liquid or solid shaped detergent compositions.
    Type: Grant
    Filed: July 22, 1998
    Date of Patent: February 20, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Laurens Nicolaas Sierkstra, Jan Klugkist, Peter Markvardsen, Claus von der Osten, Peter Bauditz
  • Patent number: 6190879
    Abstract: A method for identifying a transglutaminase-producing microorganism based on a selective assay is disclosed.
    Type: Grant
    Filed: April 20, 1999
    Date of Patent: February 20, 2001
    Assignee: Novo Nordisk A/S
    Inventors: Lisbeth Bech, Iben Angelica Nørrevang, Torben Halkier, Grethe Rasmussen, Thomas Schäfer, Jens Tønne Andersen