Abstract: A filtration cartridge having a housing with an inlet and an outlet and a filtration membrane contained within the housing and located between the inlet and the outlet is described. The membrane is sealed in such a manner that all fluid must flow through the membrane between entering the inlet and leaving the outlet of the housing. The entire cartridge, housing, membrane and any other components are all formed of one or more perfluorinated thermoplastic resins. These resins preferably are PFA, MFA, FEP and blends thereof. The membrane may be in the form of hollow fibers, wound fibers such as in a depth filter, or a flat sheet which may be formed into various configurations such as spiral filters, pleated filters, spiral pleated filters, disks and the like. These cartridges provide an inert, high temperature and acid/oxidative chemical resistant filter having properties similar to that of PTFE resins.

Abstract: Dehydrodidemnin B with useful biological activity has formula (1). It can be isolated from natural sources or synthesized, and it forms active derivatives.

Abstract: An improved dental tape treated with a substantive coating containing a crystal control substance, wherein said coating is: saliva soluble, substantially crystal-free, with a flaking value of less than about 20 and a release value of about 100.

Abstract: Disclosed are coated monofilament dental tapes with physical improvements including patient-friendly edges and self-indicating releasable coatings.

Abstract: Molecularly oriented, thermoplastic elastomeric dental tapes extruded with a melt spinning extrusion carried out at draw ratios from between about 4:1 and about 7.5:1 and draw temperatures from between about 80° and 265° C. having: elongation at break of less than about 50%, an elastic limit of less than about 25% and enhanced tape flex-twist index from between about 2.5 and about 5, with the capacity to release substantive, flake-free, saliva soluble coatings during flossing.

Abstract: Monofilament dental tapes coated with a permanent Soft Abrasive™ coating and a saliva soluble overcoating suitable for physically disrupting and/or removing biofilms, tartar and stained pellicle.

Abstract: The present invention is directed to the synthetic processes outlined in Schemes 1, 2 and 3, to the novel intermediates recited therein, and to the uses of these compounds as synthetic precursors to the pseudopterosins. Other embodiments and aspects of the present invention include the novel synthetic procedures described herein.

Abstract: The present invention is directed to the synthesis and characterization of compounds having the formula: wherein R1, R2, R3, R4, R5, R6, R7, R8 and R9 are each independently selected from the group consisting of H, OH, OR′, SH, SR′, SOR′, SO2R′, NO2, NH2, NHR′, N(R′)2, NHC(O)R′, CN, halogen, ═O, C(═O)H, C(═O)R′, CO2H, CO2R′, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, substituted or unsubstituted aryl, substituted or unsubstituted aralkyl, and substituted or unsubstituted heteroaromatic; wherein each of the R′ groups is independently selected from the group consisting of H, OH, NH2, NO2, SH, CN, halogen, ═O, C(═O)H, C(═O)CH3, CO2H, CO2CH3, C1-C12 alkyl, C2-C12 alkenyl, C2-C12 alkynyl, aryl, aralkyl, and heteroaromatic; wherein each dotted circle represents one, two or three optional double bonds; wherein R7 and R8 may be joined into a carbocyclic or heterocyclic ring system; and wherein X1 and X2

Abstract: A technique for determining blood flow in a living body by changing the thermal energy level by a predetermined amount at a site in a blood flow path and detecting temperatures at locations upstream and downstream of the site. The temperature difference at such locations is determined and the blood flow is calculated as a function of the change in energy level and of the temperature differences measured prior to and following the change in energy level.

Abstract: The use of alkali metal, alkaline earth metal, ammonium and substituted ammonium salts of alkyl and alkanol sulfonic acids as additives in pure metal and metal alloy sulfate electroplating baths has a number of unexpected benefits including wider useful current density range, improved appearance and in the case of tin improved oxidative stability. The metals and alloys include but are not limited to tin, nickel, copper, chromium, cadmium, iron, rhodium, ruthenium, iron/zinc and tin/zinc.

Abstract: Sessile marine organisms are a source of many marine pharmaceuticals. A method of producing such a marine pharmaceutical is provided which involves positioning a plurality of like substrates in sea water, growing the organism on the plurality of substrates, harvesting the grown organism, and extracting the pharmaceutical from the harvested organism.

Abstract: Various monofilament dental tapes with substantive coatings including: solutions of block copolymers and non-ionic surfactants, melt emulsions of waxes emulsified in surfactants and inverse melt emulsions of surfactants emulsified in a continuous wax phase, and their methods of manufacture are described.

Abstract: According to one embodiment of the present invention, there is provided a lanyard construction, which includes a strap forming a closed loop of flexible material adapted to be disposed about a part of a human body. An adjustable mounting element, preferably either a slide hook assembly or a universal slide attachment, is on the loop. This mounting element is used for mounting an object to be displayed or used by the wearer of the lanyard. Finally, the lanyard construction of the present invention includes a breakaway member which defines a weak point in the strap whereat the loop may open and be pulled free from the wearer. In the present invention, the user of the lanyard selects the best location for separation of the weak point from the mounting element about the periphery of the lanyard loop. Such a location may be behind the wearer's neck, or it may be some location closer to the mounting element.

Abstract: A cutting device comprising a base, a pivot thruster, and a cutting blade is disclosed. The cutting device allows for safe cutting, and, unlike other cutting devices, may not be used as a weapon. The cutting device is lightweight, inexpensive, portable, and may be operated using one hand.

Abstract: Compounds having formula (I) wherein R3, R4, R7 and R8 are independently selected from the group consisting of hydrogen, lower alkyl, halogen, amine, mono(lower)alkylamine, di(lower)alkylamine, phenyl, or substituted phenyl possess antitumor activity and are new with the exception of the compound in which R3, R4, R7, R8 are all hydrogen and the compound in which R3 and R7 are hydrogen, R4 is chlorine, and R8 is a 2-nitrophenyl group.

Abstract: A sink attachment having a basin, a drain tube, and a sealing member is disclosed. The sink attachment provides for simultaneously draining tap water or other liquids and sealing the sink. The attachment may be relocated without having to remove the sealing member from the sink drain.

Abstract: The present invention is directed to a new synthetic route to pseudopterosin aglycone (3): a key intermediate for the synthesis of a group of antiinflammatory natural products including pseudopterosin A (1) and E (2). The pathway of synthesis starts with the abundant and inexpensive (S)-(−)-limonene and its long-known cyclic hydroboration product (4) and leads to the chiral hydroxy ketone (6). Conversion of (6) to (10) followed by a novel aromatic annulation produced (15) which underwent highly diastereoselective cyclization to afford the protected pseudopterosin aglycone (16). The naturally occurring pseudopterosins such as (1) and (2) are readily available from this key intermediate.

Abstract: Disclosed are the compounds Asamarine A and B, novel cytotoxic diterpene-alkaloids, that have been isolated from the sponge Raspailia sp. The structure of these compounds have been established on the basis of NMR data and confirmed by X-ray analysis. Also disclosed are compounds (I) and (II), wherein wherein R1 represents hydrogen or lower alkyl or lower alkanoyl; R2 represents hydrogen or lower alkyl; R3 is either an alkyl or a cycloalkyl group containing one or more isoprene units, or a monoterpene or a sesquiterpene or a sesquiterpene or a diterpene group; R4 or R5 represent hydrogen or lower alkyl; R6 represents lower alkyl; and X represents F or Cl or Br or I.