Patents Represented by Attorney Henry C. Nields
  • Patent number: 4531964
    Abstract: A compound of the formula: ##STR1## wherein R.sub.4 is lower alkyl, X is oxygen or sulfur, and n is integer of 3 or 4; R.sub.1 is hydrogen or halogen; R.sub.2 is halogen; R.sub.3 is hydrogen or C.sub.1 -C.sub.8 -alkyl which may have lower alkoxy; a herbicidal composition containing said compound as an effective component; a method for killing weeds using said compound; and processes for the production of said compound, are disclosed hereinafter.
    Type: Grant
    Filed: August 29, 1983
    Date of Patent: July 30, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Shizuo Shimano, Shinichi Kobayashi, Mikio Yanagi, Osamu Yamada, Mikio Saito, Fumio Futatsuya
  • Patent number: 4530998
    Abstract: This invention relates to 2'-deoxy-oxanosine represented by the following formula: ##STR1## and process for the preparation thereof. This new compound exhibits a growth inhibiting action to gram-negative bacteria and has a carcinostatic action.
    Type: Grant
    Filed: March 5, 1984
    Date of Patent: July 23, 1985
    Assignee: Zaidan Hojin Biseibutsu Kagaku KenkyuKai
    Inventors: Hamao Umezawa, Tomio Takeuchi, Masaaki Ishizuka, Tomohisa Takita, Nobuyoshi Shimada, Kuniki Kato
  • Patent number: 4530797
    Abstract: A process for producing polychlorobenzonitrile having chlorine atoms at the 2,6-position by ammoxidation of toluene derivative having chlorine atoms at the 2,6-position with a gas containing ammonia and oxygen in vapor phase in the presence of a catalyst, characterized in that bromine and/or a bromine-containing compound is added to the reaction system.
    Type: Grant
    Filed: September 10, 1984
    Date of Patent: July 23, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Hiroshi Hayami, Yasuo Kuroda, Makoto Kikuchi, Kenji Koshi
  • Patent number: 4530916
    Abstract: A catalyst having heteropoly-acid structure and the general formula:Mo.sub.a V.sub.b P.sub.c Cu.sub.d As.sub.e X.sub.f O.sub.gwherein, X represents one or more elements selected from the group consisting of tin, lead, cerium, cobalt, iron, zirconium, thorium, tungsten, germanium, nickel, rhenium, bismuth, antimony, chromium, boron, magnesium, silver, aluminum, zinc and titanium and a, b, c, d, e, f and g represent the atomic ratio of the elements where,a is 10,b is a number of 3 or less than 3 excluding 0,c is a number of 0.5 to 6,d is a number of 3 or less than 3 excluding 0,e is a number of 3 or less than 3 excluding 0,f is a number of 0 to 3,g is a number determined depending on the valency and atomic ratio of other elements.There is also provided a process for producing methacrylic acid by oxidizing methacrolein with molecular oxygen or molecular oxygen-containing gas in the presence of the catalyst defined above.
    Type: Grant
    Filed: November 28, 1983
    Date of Patent: July 23, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mutsumi Matsumoto, Hideki Sugi
  • Patent number: 4529549
    Abstract: This invention relates to a novel spergualin-related compound and a process for the production thereof. The novel compound, which has a high antitumor activity, is represented by the general formula ##STR1## wherein R.sub.1 represents a hydrogen atom, hydroxyl group, or an aliphatic acyloxy group having 1 to 10 carbon atoms, R.sub.2 represents an amino acid residue (except for the residue of .alpha.-hydroxyglycine) formed by removing one hydrogen atom and hydroxyl group from respectively the .alpha.- or .omega.-amino group and the .alpha.-carboxyl group of an .alpha.- or .omega.-amino acid, said amino acid residue forming acid amide linkages with the adjacent carbonyl group and amino group, and m is an integer of 4 to 6.
    Type: Grant
    Filed: August 18, 1983
    Date of Patent: July 16, 1985
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Tomio Takeuchi, Rinzo Nishizawa, Katsutoshi Takahashi, Teruya Nakamura, Yoshihisa Umeda
  • Patent number: 4525299
    Abstract: (-)-15-Deoxyspergualin represented by the following formula ##STR1## a salt thereof having antitumor activity, process for the preparation thereof and intermediate thereof.
    Type: Grant
    Filed: May 10, 1983
    Date of Patent: June 25, 1985
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Tomio Takeuchi, Shinichi Kondo
  • Patent number: 4525465
    Abstract: A biospecific adsorbent comprising pyroglutamyl-lysyl-leucyl-argininal combined with a water-insoluble support is provided. This biospecific adsorbent is useful as an adsorbent for use in affinity chromatography and can be utilized for the purification of proteases such as urokinase.
    Type: Grant
    Filed: October 7, 1983
    Date of Patent: June 25, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Tetsuya Someno, Kazuo Kato, Tetsushi Saino, Shinichi Ishii, Tomio Takeuchi, Hamao Umezawa
  • Patent number: 4505038
    Abstract: A compound lever tool having a pair of interpivoted head levers with jaws and a toggle mechanism consisting of two actuating levers connected to each other by a toggle pivot and each connected to its respective head lever by a head pivot such that movement of the actuating levers towards each other spreads the rearward ends of the head levers apart and causes the jaws to close, the actuating levers each formed from sheet metal and bent to provide an upper and lower surface with each surface having aligned holes adapted to receive the toggle pivot and its respective head pivot. In the preferred embodiment the actuating levers are cloven to separate head pivot-supporting parts from the toggle pivot-supporting parts and adjustable blocks are disposed within the clefts to provide lateral support between the toggle pivot and the respective head pivots.
    Type: Grant
    Filed: November 21, 1983
    Date of Patent: March 19, 1985
    Assignee: H.K. Porter, Inc.
    Inventor: Thomas M. Porter
  • Patent number: 4500536
    Abstract: Disclosed herein are novel derivatives of N,N-substituted azolecarboxamide represented by the formula (I): ##STR1## wherein R.sub.1 represents a hydrogen atom, methyl group, ethyl group or propyl group; R.sub.2 represents an alkyl group of 1 to 6 carbon atoms; R.sub.3 represents a hydrogen atom or methyl group; A represents a hydrogen atom or methyl group; X and Y represent respectively a carbon atom or a nitrogen atom, provided that when X represents a nitrogen atom, Y represents a nitrogen atom or carbon atom and when X represents a carbon atom, Y represents a nitrogen atom; and Z represents an oxygen atom or sulfur atom, provided that when Z represents a sulfur atom, A represents only a hydrogen atom; and an agricultural or horticultural fungicidal or nematicidal composition containing the novel derivative of the formula (I) as an active ingredient.
    Type: Grant
    Filed: March 3, 1983
    Date of Patent: February 19, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Hiroshi Yoshida, Kengo Koike, Shizuo Shimano, Taizo Nakagawa, Kaoru Ohmori
  • Patent number: 4489947
    Abstract: Each player has a board having a number (N) of rows each of which comprises a number of sockets. The number of sockets in the first row is one, the number of sockets in the second row is two, the number of sockets in the third row is three, and so on up to the Nth row, which has N sockets. The game is played with a multiplicity of small pieces which fit into the sockets and which, when laid on a table with the proper orientation, reveal one of a number of N of first (or "visible") characteristics, such as color. Each small piece also has one of a number N of second (or "concealable") characteristics, such as color, which may be revealed or concealed, as desired. The small piece is constructed in such a manner that the first characteristic is always viewable whenever the second characteristic is revealed. The game apparatus also includes a die to determine the sequence of play, as well as a number N of small pieces which are wild. The game proceeds in major increments which I call "jousts".
    Type: Grant
    Filed: July 13, 1983
    Date of Patent: December 25, 1984
    Inventor: Richard H. Nolan
  • Patent number: 4490314
    Abstract: A process for making radiation cured silicone rubber articles is disclosed wherein a hydroxyl-terminated polysilaxane having a molecular weight from about 50,000 to about 2,000,000, optionally modified by mixing with up to 85% of an end-stopped silicone rubber, is mixed with from about 10 to about 70 parts per hundred of rubber of a finely divided silica filler with a particle size in the reinforcing range and other inert fillers as determined by desired final properties; the composition so prepared is formed into the desired shape at room temperature; the article so formed is precured to improve the mechanical properties of the material with which it is made by exposure to ammonia gas, ammonium hydroxide, or to the vapors or solutions of a volatile amine at room temperature; and the precured article is irradiated with high energy electrons or gamma radiation to effect a permanent cure of the material from which the article is formed.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: December 25, 1984
    Assignee: High Voltage Engineering Corporation
    Inventors: John G. DuPont, Paul A. Goodwin
  • Patent number: 4488885
    Abstract: A charging apparatus constructed to provide a continuous ac voltage and periodic pulses between the corona electrodes and non-corona electrodes contained therein.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: December 18, 1984
    Assignee: High Voltage Engineering Corporation
    Inventor: Helmut I. Milde
  • Patent number: 4485428
    Abstract: A high voltage pulse generator is provided which so interacts with the parameters of an electrostatic precipitator that excellent pulse waveforms are obtained more efficiently by using less elaborate components than heretofore required. A major feature of the invention is the charging of the pulse forming network through the high-voltage d.c. source which energizes the precipitator for charge-particulate removal.
    Type: Grant
    Filed: May 10, 1982
    Date of Patent: November 27, 1984
    Assignee: High Voltage Engineering Corp.
    Inventor: Neville W. Harris
  • Patent number: 4474696
    Abstract: Reactive azo dyestuffs which, in the form of free acid, are represented by the following formula: ##STR1## (wherein R is hydrogen or methyl) are characterized by exhibiting the following properties: high fixation efficiency, excellent wash-off, high build-up and excellent wet fastness. Such dyestuffs give dyeings excellent in light fastness, chlorine fastness and color yield.
    Type: Grant
    Filed: June 3, 1980
    Date of Patent: October 2, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Setsuzo Takahashi, Hideo Inoue, Hideo Otake, Hiroshi Senoo
  • Patent number: 4472190
    Abstract: A new N-substituted tetrahydroisophthalimde derivative represented by the formula: ##STR1## Wherein R.sub.1 and R.sub.2 are hydrogen or halogen, R.sub.3 is hydrogen or lower alkyl and R.sub.4 is alkyl which may be substituted by halogen or lower alkoxy, and preparation methods thereof and herbicidal composition comprising one or more of said derivatives as active ingredients, is disclosed.
    Type: Grant
    Filed: August 18, 1982
    Date of Patent: September 18, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mikio Yanagi, Osamu Yamada, Fumio Futatsuya, Atsuhiko Shida
  • Patent number: 4467113
    Abstract: A catalyst having heteropoly-acid structure and the general formula:Mo.sub.a V.sub.b P.sub.c Cu.sub.d As.sub.e X.sub.f O.sub.gwherein,X represents one or more elements selected from the group consisting of tin, lead, cerium, cobalt, iron, zirconium, thorium, tungsten, germanium, nickel, rhenium, bismuth, antimony, chromium, boron, magnesium, silver, aluminum, zinc and titanium and a, b, c, d, e, f and g represent the atomic ratio of the elements where,a is 10,b is a number of 3 or less than 3 excluding 0,c is a number of 0.5 to 6,d is a number of 3 or less than 3 excluding 0,e is a number of 3 or less than 3 excluding 0,f is a number of 0 to 3,g is a number determined depending on the valency and atomic ratio of other elements.There is also provided a process for producing methacrylic acid by oxidizing methacrolein with molecular oxygen or molecular oxygen-containing gas in the vapor phase in the presence of the catalyst defined above.
    Type: Grant
    Filed: November 19, 1979
    Date of Patent: August 21, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mutsumi Matsumoto, Hideki Sugi
  • Patent number: 4464532
    Abstract: A novel process for producing 7-alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone, and its intermediates. 7-Alkoxycarbonyl-6,8-dimethyl-4-hydroxymethyl-1-phthalazone can be obtained by reacting substituted methylenetriphenylphosphorane with 3,5-dimethyl-4-alkoxycarbonylphthalic anhydride to obtain 6-alkoxycarbonyl-5,7-dimethyl-.DELTA..sup.3,.alpha. -substituted methylenephthalide, reacting the latter with hydrazine to obtain a phthalazone derivative, hydrolyzing the latter, halogenating the hydrolyzate to obtain 7-alkoxycarbonyl-6,8-dimethyl-4-(.alpha.-halogeno-.alpha.-substituted methyl)-1-phthalazone and then directly hydrolyzing and decarboxylating the latter or, when said 7-alkoxycarbonyl-6,8-dimethyl-4-(.alpha.-halogeno-.alpha.-substituted methyl)-1-phthalazone is 7-alkoxycarbonyl-6,8-dimethyl-1-phthalazone-4-.alpha.
    Type: Grant
    Filed: June 7, 1982
    Date of Patent: August 7, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yukio Takei, Masao Yoshida, Rinzo Nishizawa
  • Patent number: 4453945
    Abstract: The present invention relates to a process for dyeing cellulose fibers or its union fibers which is effected according to an exhaustion dyeing method using a reactive dye containing at least one s-triazinyl group having a group of the formula: ##STR1## wherein M represents a hydrogen or an alkali metal, in an aqueous dyeing bath having a pH in the range of 4 to 10 and a dyeing temperature in the range of 110.degree. C. to below 140.degree. C.
    Type: Grant
    Filed: April 19, 1983
    Date of Patent: June 12, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masakatsu Miyamoto, Yoshiharu Suzuki, Masayoshi Ojima, Yutaka Iizuka, Ryuzo Orita, Tadashi Matsuo
  • Patent number: 4452996
    Abstract: Di(meth)acrylate esters of the formula: ##STR1## wherein m and n each represents O or an integer of 1 to 3, the average sum of m+n being 1 to 6 and R represents hydrogen or a methyl group, and process for producing the same.The esters are copolymerizable with other unsaturated compounds to form radiation hardenable films with a reduced irritating effect.
    Type: Grant
    Filed: January 27, 1983
    Date of Patent: June 5, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Minoru Yokoshima, Kazuyoshi Nawata, Tetsuo Hironaka, Hideaki Takahashi
  • Patent number: 4433167
    Abstract: A catalyst comprising (1) palladium, (2) phosphorus, (3) antimony, (4) X and (5) oxygen wherein X denotes at least one element selected from the group consisting of potassium, sodium, rubidium, lithium, cerium, beryllium, magnesium, calcium, vanadium, strontium, zinc, thorium and rhenium.There is also provided a process for the manufacture of methacrylic or acrylic acid by oxidizing methacrolein or acrolein with molecular oxygen in the vapor phase in the presence of the catalyst defined above.
    Type: Grant
    Filed: March 4, 1982
    Date of Patent: February 21, 1984
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Masanobu Ogawa, Toshitake Kojima