Patents Represented by Attorney Henry C. Nields
  • Patent number: 4918208
    Abstract: A process for producing 7-dimethylamino-6-demethyl-6-deoxytetracycline (minocycline) which comprises treating the reaction liquid containing minocycline and formaldehyde with hydroxylamine or urea, the reaction liquid being obtained after reductive methylation of 7-amino-6-demethyl-6-deoxytetracycline by using aldehyde, then subjecting the reaction liquid to an adsorption treatment with a nonionic adsorption resin (adsorbent), and subsequently eluting the intended product adsorbed to the adsorbent.
    Type: Grant
    Filed: July 22, 1988
    Date of Patent: April 17, 1990
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Ryoichi Hasegawa, Hiroaki Ohno, Kazuaki Sano, Yoshinori Saito
  • Patent number: 4909701
    Abstract: In a material transfer device, an articulated arm assembly extends and retracts in a "froglike" motion to transfer an object between a plurality of locations. The articulated arm assembly is rotatable about a pivot point in a radial plane and can be raised or lowered in an axial direction to align the object with the intended destination. A greater degree of axial mobility may be provided, for example by a rotating lift screw. A vacuum chamber may be provided, with the arm assembly moving the object between locations in the chamber.
    Type: Grant
    Filed: May 18, 1987
    Date of Patent: March 20, 1990
    Assignee: Brooks Automation Inc.
    Inventors: E. Brian Hardegen, Todd E. Bottomley, James C. Davis, Jr.
  • Patent number: 4906980
    Abstract: The start of the final tightening of a screwdriver and rotation of the screwdriver after the start of the final tightening are detected. The detected rotation is compared with a standard value. The screwdriver should rotate very little during the final tightening, if it is normally operated. Consequently when the detected rotation is more than the standard value, one may assume false rotation of the screwdriver has occurred.
    Type: Grant
    Filed: December 15, 1988
    Date of Patent: March 6, 1990
    Assignee: Hayashi Tokei Kogyo Kabushiki Kaisha
    Inventor: Kenji Fukuhara
  • Patent number: 4905816
    Abstract: The invention provides an apparatus for conveying steel bar materials sent from the exit of a stand of 2 strand rolling line to a cooling hearth, in which improved conveying and dropping of the bar materials is accomplished. Four conveying/dropping components are arranged in two pairs, which are disposed at determined positions, so that the bar materials may avoid being bent or twisted during conveying and dropping, and the treating speed of the rolling line is accelerated.
    Type: Grant
    Filed: January 21, 1988
    Date of Patent: March 6, 1990
    Assignee: Nippon Kokan Kabushiki Kaisha
    Inventors: Giichi Matsuo, Noburu Masuda, Tamiyasu Kosugi
  • Patent number: 4904585
    Abstract: This invention relates to a novel antibiotic NK84-0218 of the formula: ##STR1## which exhibits antibacterial, antiviral and antineo-plastic activities and is expected as a pharmaceutical as well as a process for the production of the same.
    Type: Grant
    Filed: November 2, 1987
    Date of Patent: February 27, 1990
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Nobuyoshi Shimada, Shigeru Hasegawa, Takashi Harada, Takayuki Tomizawa, Akio Fujii
  • Patent number: 4901088
    Abstract: A coincidence-preventing circuit prevents the graininess of image which results form coincidental arrival of a clock pulse and a load pulse at a circuit, such as a down counter, the output from which controls the timing and density of the image produced on a recording medium by an ink jet.
    Type: Grant
    Filed: February 19, 1988
    Date of Patent: February 13, 1990
    Inventors: Carl H. Hertz, Bo A. Samuelsson
  • Patent number: 4898996
    Abstract: A process for producing 3-chloro-4-fluoronitrobenzene which is characterized by chlorinating 4-fluoronitrobenzene in the presence of:(1) iodine or an iodide in combination with iron or an iron compound or(2) iodine or an iodide in combination with antimony or an antimony compound.
    Type: Grant
    Filed: June 23, 1988
    Date of Patent: February 6, 1990
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Tsukasa Ishikura, Tatuharu Fukushima
  • Patent number: 4892876
    Abstract: A pharmaceutical composition for inhibiting Human Immunodeficiency Virus (HIV), which is characterized by comprising a compound represented by the formula (1) ##STR1## or a pharmaceutically acceptable salt thereof as an active ingredient.
    Type: Grant
    Filed: March 24, 1988
    Date of Patent: January 9, 1990
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Hiroo Hoshino, Nobuyoshi Shimada
  • Patent number: 4889775
    Abstract: The present invention relates to a highly corrosion resistant surface-treated steel plate. The steel plate of the invention comprises a zinc deposition or zinc alloy deposition film as the undercoat deposition layer, a chromate film formed on the undercoat deposition layer and a film of a resin composition formed on the chromate film. This resin composition comprises a substrate resin formed by adding at least one basic nitogen atom and at least two primary hydrogen groups to terminal of an epoxy resin, silica and sparingly water soluble Cr compound. The resin composition may comprise a polyisocyanate compound as the curing agent. Moreover, the resin composition may comprise a silane compound as the crosslinking agent for the substrate resin and silica.
    Type: Grant
    Filed: February 25, 1988
    Date of Patent: December 26, 1989
    Assignees: Nippon Kokan Kabushiki Kaisha, Kansai Paint Co., Ltd.
    Inventors: Takeshi Adaniya, Masaaki Yamashita, Takahiro Kubota, Akira Enatsu, Norio Nikaido, Yoshiaki Miyosawa, Tadashi Nishimoto
  • Patent number: 4887322
    Abstract: A toilet seat lowering device for a hinged seat and cover assembly. The device is either made of resilient material or is a spring-like mechanism which is placed on the cover of a toilet near the hinge. When the seat is manually raised the device is compressed and will repel the seat and prevent the seat from remaining in a raised position.
    Type: Grant
    Filed: April 1, 1987
    Date of Patent: December 19, 1989
    Inventor: Lydon
  • Patent number: 4887955
    Abstract: A unit injector for fuel combustion is integrally structured with an injection pumping mechanism and an injection valve mechanism. A housing is fixedly united with an injection pumping part and an injection valve part, the injection pumping part being formed with a stepped insertion hole, and the injection valve part being formed with an oil path extending toward a nozzle body at an end thereof concentrically. A barrel has a hole for guiding a plunger, and fuel inlet and outlet ports, the shape and outer diameter of which are finishing-processed for coinciding with the insertion hole, and the barrel is shrunken in size by cooling and inserted into the insertion hole while it is cooled, and exactly fitted into the insertion hole when the shrinked barrel is recovered to the initial size by returning to the room temperature and supported at an inner diametered part and a stepped part.
    Type: Grant
    Filed: May 17, 1989
    Date of Patent: December 19, 1989
    Assignee: Diesel Kiki Co., Ltd.
    Inventors: Iwao Maruyama, Hidetoshi Saitoh
  • Patent number: 4886544
    Abstract: Disclosed herein is a novel steroids represented by the formula (1): ##STR1## wherein Z represents ##STR2## n is integer of 1 to 3, R represents hydrogen, halogen, CF.sub.3, lower alkyl, lower alkoxy or --CO.sub.2 R', wherein R' represents hydrogen, alkali metal or lower alkyl, andR.sup.1, R.sup.2, R.sup.3 and R.sup.4 represent hydrogen or acyl, respectively.The compound of the formula (1) of the present invention exhibits high durability as well as excellent plant growth regulation.
    Type: Grant
    Filed: March 3, 1988
    Date of Patent: December 12, 1989
    Inventors: Sei-ichi Hayashi, Tadashi Hohjoh, Atsuhiko Shida, Nobuo Ikekawa
  • Patent number: 4883167
    Abstract: A continuous conveyor apparatus is provided, comprising tandem wheels and coaxial wheels appropriately positioned. Four endless link chains are turned around the wheels, and a plurality of carrying vessels having arms are connected to the four link chains through the arms. The coaxial wheels have a pair of inner wheels and a pair of outer wheels coaxially arranged. The tandem wheels have a pair of inner wheels and a pair of outer wheels horizontally arranged with a space therebetween. The apparatus is durable, lightweight and can be produced at low cost.
    Type: Grant
    Filed: September 8, 1987
    Date of Patent: November 28, 1989
    Inventor: Katsuaki Shibata
  • Patent number: 4881926
    Abstract: Rotation speed of automotive auxiliary machines is controlled by a drive pulley provided on a crank shaft and a driven pulley communicating with the drive pulley through a V-belt. The drive pulley comprises a rigid pulley secured on a drive shaft, a guide holder to be rotated together with the drive shaft by a mount bolt, and a slide pulley axially-movably located between the guide holder and the rigid pulley. The slide pulley provides a power piston to be moved along a guide holder shaft. The power piston, the guide holder flange, and the slide pulley define a power piston chamber.Inside of the power piston chamber are located a flyweight to be moved by centrifugal force and a servo valve to be axially moved by the flyweight. The servo valve is fitted on the outer peripheral surface of the power piston.
    Type: Grant
    Filed: November 29, 1988
    Date of Patent: November 21, 1989
    Assignee: Diesel Kiki Co., Ltd.
    Inventors: Hachiro Aoki, Tadashi Kobayashi, Junya Kuronuma, Hideya Kikuchi
  • Patent number: 4860730
    Abstract: Apparatus for using solar energy to transport or heat the air within a structure is disclosed. The apparatus includes a chamber defined by a recipient element attached to a hull-like shaped absorbent element. The chamber includes entrance and exit apertures in fluid communication with the air within a structure by means of valves, which regulate the flow of fluid in and out of said apertures. A thrust-reducing support system is also provided to compensate for various external forces.
    Type: Grant
    Filed: October 5, 1987
    Date of Patent: August 29, 1989
    Inventors: Sergio Capilli, Anna D. Capilli
  • Patent number: 4851446
    Abstract: The present invention relates to an immunosuppressing method which comprises administering a spergualin-related compound represented by the following formula ##STR1## (wherein R.sub.1 is --(CH.sub.2).sub.4 --, --(CH.sub.2).sub.6 --, ##STR2## R.sub.2 is --(CH.sub.2).sub.2 -- or --CH.dbd.CH--; and R.sub.3 is ##STR3## or pharmacologically acceptable salts thereof in an effective amount to a warm-blood animal.
    Type: Grant
    Filed: March 6, 1987
    Date of Patent: July 25, 1989
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, deceased, Tomio Takeuchi, Masaaki Ishizuka, Fuminori Abe, Akio Fujii, Teruya Nakamura
  • Patent number: 4844412
    Abstract: Provided is a device mounted on one end of valve body, remote from a manipulation lever attached to the other end of the spool, for retaining the spool at an offset position other than a position to which the spool is returned by the force of a return spring, wherein a shaft coaxial with the spool is formed directly therein with a linear guide section, a ring-like projection and a detent section, thereby the spool is retained not by pushing out balls in the direction radial from the axis of the spool, that is in the direction toward the inner wall of a casing, but by dropping the balls in the centripetal direction, that is, the direction toward the axis of the spool.
    Type: Grant
    Filed: December 18, 1987
    Date of Patent: July 4, 1989
    Assignee: Diesel Kiki Co., Ltd.
    Inventor: Shigeru Kubozono
  • Patent number: 4845215
    Abstract: The present invention relates to a novel compound having hypoxanthine base represented by the following formula: ##STR1## as well as to use of said compound and process for producing said compound.The novel compound of the present invention has an immunosuppressive and antiviral actions and is expected to be useful as a medical drug.
    Type: Grant
    Filed: May 26, 1987
    Date of Patent: July 4, 1989
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Nobuyoshi Shimada, Takayuki Tomizawa, Shigeru Hasegawa, Kaoru Matsuo, Akio Fujii, Hiroo Hoshino
  • Patent number: 4844982
    Abstract: High strength, flexible compositions with improved mechanical properties at elevated temperatures for wire insulation coatings and other shaped articles used in hostile environments are disclosed, consisting of a high temperature fluorocarbon polymer, such as an ethylene-tetrafluoroethylene copolymer or the like, and from about 1% wt. to about 50% wt. of a polyvinylidene fluoride compound.
    Type: Grant
    Filed: February 26, 1987
    Date of Patent: July 4, 1989
    Assignee: High Voltage Engineering Corporation
    Inventor: Frank J. Glaister
  • Patent number: 4845235
    Abstract: A pyrroline derivative represented by the formula: ##STR1## wherein R.sub.1 and R.sub.2 each independently stand for an alkyl (C.sub.1-6), allyl, alkoxy (C.sub.1-6) ethyl, allyloxyethyl, phenoxyethyl, phenylalkyl (C.sub.1-3), alkoxy (C.sub.1-6) carbonylalkyl (C.sub.1-3) or phenoxyethoxycarbonylalkyl (C.sub.2-3) group and R.sub.3 stands for a hydrogen atom or R.sub.3 ', wherein R.sub.3 ' stands for an alkyl (C.sub.1-6), allyl, benzyl, chlorobenzyl, nitrobenzyl, phenethyl, alkoxy (C.sub.1-6) carbonylalkyl (C.sub.1-3), phenoxyethoxycarbonylalkyl (C.sub.2-3) or cyanoalkyl (C.sub.1-2) group, a process for producing a pyrroline derivative represented by the formula (I) and methods for dyeing a hydrophobic fiber and coloring a synthetic resin with the same.
    Type: Grant
    Filed: May 15, 1987
    Date of Patent: July 4, 1989
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Hiroyuki Matumoto, Hidenori Imai, Shozi Tada