Patents Represented by Attorney Henry C. Nields
  • Patent number: 4666642
    Abstract: High strength, flexible compositions with improved mechanical properties at elevated temperatures for wire insulation coatings and other shaped articles used in hostile environments are disclosed, consisting of a high temperature fluorocarbon polymer, such as an ethylene-tetrafluoroethylene copolymer or the like, and from about 1% wt. to about 50% wt. of a polyvinylidene fluoride compound.
    Type: Grant
    Filed: August 2, 1985
    Date of Patent: May 19, 1987
    Assignee: High Voltage Engineering Corporation
    Inventor: Frank J. Glaister
  • Patent number: 4667054
    Abstract: This invention relates to a process for producing optically active valine, characterized by optically resolving DL-valine hydrochloride in a solvent containing an amine salt, a sulfonic acid or a carboxylic acid and isolating optically active valine after the decomposition of the obtained optically active valine hydrochloride.
    Type: Grant
    Filed: January 30, 1986
    Date of Patent: May 19, 1987
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Yoshinobu Miyazawa, Noriko Ooishi, Shigeru Aoki, Yasuhisa Tashiro
  • Patent number: 4666507
    Abstract: Disclosed is a compound exhibiting herbicidal activity of the formula: ##STR1## wherein R.sup.1 is hydrogen, halogen or methyl, R.sup.2 is hydrogen, halogen or lower alkyl, R.sup.3 is lower alkyl which may be substituted by halogen or methylsulfonyl, benzyl or phenyl which may be substituted by halogen or nitro, R.sup.4 is hydrogen; lower alkyl which may be substituted by carboxy or lower alkoxycarbonyl; lower alkenyl; lower alkynyl; methylsulfonyl or benzyl which may be substituted by halogen, X is hydrogen, halogen or C.sub.1 -C.sub.2 -alkyl, Y is C.sub.1 -C.sub.2 -alkyl, X may make --(CH.sub.2).sub.3 -- or --(CH.sub.2).sub.4 -- together with Y, W is halogen.
    Type: Grant
    Filed: December 30, 1985
    Date of Patent: May 19, 1987
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mikio Yanagi, Shuji Kawada, Fumio Futatsuya, Kenji Kobayashi
  • Patent number: 4659722
    Abstract: Disclosed is the compound of the formula: ##STR1## wherein X is oxygen, sulfur or ##STR2## R.sub.1 is 3-pyridyl or 4-pyridyl, R.sub.2 is C.sub.1 .about.C.sub.12 -alkyl; C.sub.3 - or C.sub.4 -alkenyl; C.sub.5 - or C.sub.6 -cycloalkyl which may be substituted by C.sub.1 - or C.sub.2 -alkyl; pyridyl; pyridylmethyl; phenethyl cyanoalkyl having 1 or 2 carbon atoms; methoxyethyl; 1-methylmethoxypropyl; phenyl; phenyl which is substituted by one or more of C.sub.1 .about.C.sub.4 -alkyl, C.sub.1 .about.C.sub.4 -alkoxy, nitro, halogen, trifluoromethyl, allyl and methoxycarbonyl; benzyl; benzyl which is substituted by one or more of methyl, nitro, methoxy and chloro; .alpha.-methylbenzyl; C.sub.1 .about.C.sub.6 -alkyl which is substituted by halogen when X is oxygen or ##STR3## C.sub.2 - or C.sub.3 -alkyl which is substituted by dimethylamino, furfuryl or thienylmethyl; R.sub.3 is hydrogen, C.sub.1 .about.C.sub.4 -alkyl, cyanomethyl, methoxycarbonylmethyl, or 1-propoxycarbonylmethyl. These compounds are bactericides.
    Type: Grant
    Filed: August 1, 1985
    Date of Patent: April 21, 1987
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Taizo Nakagawa, Eiichi Tanaka, Kengo Koike, Hiromi Yoshida, Hiroshi Yoshida
  • Patent number: 4652673
    Abstract: A process for producing methacrylic acid by vapor phase oxidation of methacrolein with molecular oxygen or molecular oxygen-containing gas in the presence of isobutylene and/or tertiary butanol and in the presence of a catalyst having a heteropolyacid structure represented by the following general formula:Mo.sub.a V.sub.b P.sub.c X.sub.d O.sub.ewherein Mo, V, P, and O represent molybdenum, vanadium, phosphorus, and oxygen respectively, X represents the coexistence of copper and aresenic and the a, b, c, d and e represent the atomic ratio of the elements where:a is 10,b is a number of 6 or less excluding 0,c is a number of 0.5 to 6,d is a number of 3 or less excluding 0, ande is a number determined depending on the valance and atomic ratio of the other elements.
    Type: Grant
    Filed: May 18, 1983
    Date of Patent: March 24, 1987
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Mutsumi Matsumoto, Kouichi Wada
  • Patent number: 4647638
    Abstract: Novel organophosphates of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each represents H or CH.sub.3, m is a numeral of 1-5 and n is a numeral of 1-2, and adhesives comprising them.
    Type: Grant
    Filed: November 18, 1985
    Date of Patent: March 3, 1987
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Minoru Yokoshima, Tetsuo Ohkubo
  • Patent number: 4637955
    Abstract: High strength, flexible compositions with improved mechanical properties at elevated temperatures for wire insulation coatings and other shaped articles used in hostile environments are disclosed, consisting of a high temperature fluorocarbon polymer, such as an ethylene-tetrafluoroethylene copolymer or the like, and from about 1% wt. to about 50% wt. of a polyvinylidene fluoride compound.
    Type: Grant
    Filed: October 26, 1984
    Date of Patent: January 20, 1987
    Assignee: High Voltage Engineering Corporation
    Inventor: Frank J. Glaister
  • Patent number: 4627844
    Abstract: A coextruded tri-layered medical-surgical tubing for the administration of common medicines such as insulin and nitroglycerin solutions is disclosed. Improved flexibility and uniformity and increased peel strength are obtained by interposing a layer of an ethylene-vinyl acetate copolymer between an outer layer of polyvinyl chloride and a core layer of low-density polyethylene. The composite tubing exhibits excellent fluid flow characteristics and is readily employed in the transportation of intravenous fluids and the like without absorbtion or contamination difficulties.
    Type: Grant
    Filed: October 30, 1985
    Date of Patent: December 9, 1986
    Assignee: High Voltage Engineering Corporation
    Inventor: Jerry A. Schmitt
  • Patent number: 4628111
    Abstract: The present invention relates to new easily filtrable, non-hygroscopic N-benzyloxycarbonyl-L-threonine amide hemihydrate.
    Type: Grant
    Filed: April 16, 1985
    Date of Patent: December 9, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Akihiro Mashiba, Kazuteru Hagita, Yoshinobu Miyazawa, Tetsushi Saino, Yasuhisa Tashiro
  • Patent number: 4625677
    Abstract: An apparatus for coating and polishing a micropipette for patch recording comprises an inverse microscope having a stage for supporting a micropipette to be processed, and a pair of objectives of relatively low and relatively high magnification, respectively, which are adapted to be selectively placed into the optical path of the microscope. An air gun is positioned to supply an air jet to a pipette supported on the stage, said gun comprising heating means for selectively producing a hot and a cold air jet. An attchment comprising an electricially heatable filament is associated to the objective of relatively high magnification. The micropipette is positioned and coated under observation with the aid of the objective of low magnification and then the coating is cured by applying the hot air jet. Subsequently, the tip of the pipette is polished by the heated filament under observation with the aid of the objective of high magnification.
    Type: Grant
    Filed: May 23, 1985
    Date of Patent: December 2, 1986
    Assignee: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
    Inventor: Erwin Neher
  • Patent number: 4608400
    Abstract: A novel (meth)acrylate represented by the general formula [I]: ##STR1## wherein R.sub.1 stands for a hydrogen atom or an alkyl group having 1 to 12 carbon atoms; R.sub.2 and R.sub.3 each stand for a hydrogen atom or a methyl group; the mean value of m is 1 to 10 and the mean value of n is 1 to 10 and a resin composition comprising the same.
    Type: Grant
    Filed: July 8, 1985
    Date of Patent: August 26, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Minoru Yokoshima, Tetsuo Ohkubo, Masayuki Kiyomoto
  • Patent number: 4582928
    Abstract: This invention relates to a process for producing optically active phenylalanine, characterized by optically resolving DL-phenylalanine.optically active mandelic acid complexes in an aqueous solvent in the presence of an acidic compound having a pKa value of 0.90 to 2.10 and isolating optically active phenylalanine from the obtained optically active phenylalanine.optically active mandelic acid complex.According to the process of the present invention, it is possible to decrease the amount of a mother liquor of resolution to 1/5 to 1/10 of that when no acidic compound is used and to obtain optically active phenylalanine having an optical purity of as high as 96.5% or above without a step of optical purification when optically active phenylalanine is isolated from the obtained optically active phenylalanine.optically active mandelic acid complex.
    Type: Grant
    Filed: March 27, 1985
    Date of Patent: April 15, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Shigeru Aoki, Mamoru Katagiri, Ryoichi Hasegawa, Akikazu Mitsunobu, Yasuhisa Tashiro
  • Patent number: 4581180
    Abstract: Novel organophosphates of the general formula: ##STR1## wherein R.sub.1 and R.sub.2 each represents H or CH.sub.3, m is a numeral of 1-5 and n is a numeral of 1-2, and adhesives comprising them.
    Type: Grant
    Filed: April 30, 1985
    Date of Patent: April 8, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Minoru Yokoshima, Tetsuo Ohkubo
  • Patent number: 4564675
    Abstract: Disclosed herein are a process for producing 4'-demethyl-epipodophyllotoxin-.beta.-D-ethylidene-glucoside of the formula (II) comprising (A) reacting 4'-halogenoacetyl-4'-demethyl-epipodophyllotoxin-.beta.-D-2,3-di-O-halogen oacetyl-4,6-O-ethylidene-glucoside of the formula (I) with an amine and/or ammonia, or (B) subjecting the acyl-derivative (I) to alcoholysis in the presence of a catalyst, thereby removing the halogenoacetyl groups of the acyl-derivative (I) to obtain the compound (II), the acyl-derivative (I), and the use of the acyl-derivative (I) for synthesizing the compound (II) ##STR1## wherein R represents a halogenoacetyl group represented by the formula--COCH.sub.2 Xwherein X is a halogen atom.
    Type: Grant
    Filed: September 6, 1983
    Date of Patent: January 14, 1986
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Katsuhiko Kurabayashi, Hidefumi Kinoshita, Hitoshi Saito, Toshio Takahashi
  • Patent number: 4561880
    Abstract: A compound of the formula: ##STR1## wherein Z is ##STR2## wherein R.sub.4 is lower alkyl, X and Y are oxygen or sulfur and n is an integer of 3 to 6, R.sub.1 is hydrogen or halogen, R.sub.2 is halogen and R.sub.3 is hydrogen or C.sub.1 -C.sub.8 -alkyl which may have lower alkoxy; a herbicidal composition containing said compound as an effective component; a method for killing weeds using said compound; and processes for the production of said compound, are disclosed hereinafter.
    Type: Grant
    Filed: August 16, 1983
    Date of Patent: December 31, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Shizuo Shimano, Shinichi Kobayashi, Mikio Yanagi, Osamu Yamada, Atsuhiko Shida, Fumio Futatsuya
  • Patent number: 4559362
    Abstract: This invention relates to an immunopotentiator or an immunopotentiating method using spermidine or its pharmacologically acceptable salt as an active ingredient.
    Type: Grant
    Filed: November 9, 1983
    Date of Patent: December 17, 1985
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai
    Inventors: Hamao Umezawa, Tomio Takeuchi, Masaaki Ishizuka
  • Patent number: 4556735
    Abstract: The invention relates to Spergualin-related compounds of the formula: ##STR1## (wherein R.sub.1 is a lower alkylene group which may be substituted by a hydroxymethyl group; X is a hydrogen atom or a halogen atom; m and n are each 0 or an integer of 1 to 5) and salts thereof and a process for producing the same.
    Type: Grant
    Filed: February 27, 1985
    Date of Patent: December 3, 1985
    Assignee: Zaidan Hojin Biseibutsu Kagaku Kenkyukai
    Inventors: Hamao Umezawa, Tomio Takeuchi, Rinzo Nishizawa, Katsutoshi Takahashi, Teruya Nakamura, Yoshihisa Umeda
  • Patent number: 4541634
    Abstract: Each player has a board having a number (N) of rows each of which comprises a number of sockets. The number of sockets in the first row is one, the number of sockets in the second row is two, the number of sockets in the third row is three, and so on up to the Nth row, which N sockets. The game is played with a multiplicity of small pieces which fit into the sockets and which, when laid on a table with the proper orientation, reveal one of a number of N of first (or "visible") characteristics, such as color. Each small piece also has one of a number N of second (or "concealable") characteristics, such as color, which may be revealed or concealed, as desired. The small piece is constructed in such a manner that the first characteristic is always viewable whenever the second characteristic is revealed. The game apparatus also includes a die to determine the sequence of play, as well as a number N of small pieces which are wild. The game proceeds in major increments which I call "jousts".
    Type: Grant
    Filed: February 4, 1985
    Date of Patent: September 17, 1985
    Inventor: Richard H. Nolan
  • Patent number: 4542208
    Abstract: Water-soluble azo compounds which, in the free acid form, are represented by the formula: ##STR1## wherein one of X and Y is hydrogen and the other is --SO.sub.3 H; one of A and B is hydrogen and the other is --SO.sub.3 H; each of R.sub.1, R.sub.2, R.sub.3 and R.sub.4 is independently hydrogen, methyl group, ethyl group, methoxy group, ethoxy group, acylamino group or ureido group; and each of R.sub.5 and R.sub.6 is independently hydrogen, methyl group, ethyl group, methoxy group, ethoxy group, acylamino group, chlorine, hydroxyl group or carboxyl group, and a method for dyeing cellulose fibers, blended yarn fabrics of cellulose fibers with other kinds of fibers, particularly with polyester fibers, using the said compounds.
    Type: Grant
    Filed: October 6, 1983
    Date of Patent: September 17, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Junji Odani, Shigeyuki Watanabe
  • Patent number: 4536588
    Abstract: Acetal glycol diacrylates of the formula: ##STR1## wherein R.sub.1 represents H or CH.sub.3 and R.sub.2 represents CH.sub.3, C.sub.2 H.sub.5 or C.sub.3 H.sub.7,and a process for producing them are provided.
    Type: Grant
    Filed: June 13, 1983
    Date of Patent: August 20, 1985
    Assignee: Nippon Kayaku Kabushiki Kaisha
    Inventors: Minoru Yokoshima, Kazuyoshi Nawata, Tetsuo Ohkubo, Hideaki Hattori