Abstract: 2,2-Dimethyl-3,4-dihydro-2H-benzo[b]pyran-3-ols bearing an amino group in the 4-position and a cyano group in the benzo ring, their salts, esters and ethers, demonstrate excellent vasodilatory activity. The compounds, of which trans-2,2-dimethyl-4-isopropylamino-6-cyano-3,4-dihydro-2H-benzo[b]pyran-3 -ol is a representative embodiment, can be prepared from the corresponding 3,4-epoxy derivative upon treatment with an amine.

Abstract: A hardenable composition which comprises (i) a poly(carboxylic acid) or precursor thereof (as herein defined); (ii) a particulate ion-leachable silicate, aluminosilicate or metal oxide reactable with (i) in the presence of water to set to a hardened composition; and (iii) a compound comprising at least one phosphorus-carbon or phosphorus-boron covalent bond, in an amount effective in service to extend the working time of the composition.

Abstract: A compound of formula I ##STR1## in which formula: R.sub.1 represents hydrogen or an alkyl group;R.sub.2 -R.sub.5 represent hydrogen, alkyl aryl, aralkyl or alkaryl group; andn is 1 or 2.

Abstract: A novel portable fuel composition comprises 10 parts by weight of combustible polymer such as polypropylene, 20-35 parts by weight of organic solvent such as petroleum solvent and 3-9 parts by weight of coarse powder of fiber material such as sawdust, and optionally metal powder and dye. The composition is convenient for carrying and has a high degree of viscosity and calorific value. It can be utilized as a fuel for camping, for emergency, for preheating of a liquid fuel stove, for a simple portable cooking stove, or as a starter for igniting firewood.

Abstract: A cap 2 for a dispensing container 1 for a liquid, has an outlet orifice 9 sealable by a plug 15 formed on a flexible band 11 which is hingedly attached 16, 20 to the cap and which, when the plug 15 is removed from the orifice 9, forms a hanging support for the container 1, the band lying in the same vertical plane in both the open and closed positions.The cap is useful for containers for shower gels and the like, where it is necessary to hang the container from a support during use.The cap can also be adapted to contain two orifices each serving a separate compartment of a twin-compartment pack.

Abstract: Abietamide derivatives of the formula I ##STR1## wherein X is NZ wherein Z is hydrogen, alkyl, unsubstituted or substituted phenyl or X is a sulphur atom; when X is NZ, V is nitrogen, W is , and R is hydrogen or alkyl and when X is a sulphur atom, V is , W is nitrogen, and R is hydrogen, alkyl, phenyl or --CH.sub.2 COOR'; wherein R' is hydrogen or alkyl and is a single or double bond, are useful for treating hyperlipemia and particularly for the prevention and therapy of arteriosclerosis.

Abstract: Moisture vapor transmitting wound dressings are described which comprise (a) a conformable backing layer which has an adhesive on one of its surfaces and in which at least one of the backing layer and adhesive layer is continuous so as to provide a barrier both to bacteria and to liquid water when the dressing is in place on a wound and (b) a low wound adherency absorbent pad positioned on the adhesive side of the backing layer. The area of the pad is less than that of the backing layer so that an adhesive margin remains exposed on two, or preferably four, sides of the pad so that the backing layer may be adhered to the skin surrounding the wound area. The wound dressings have a moisture vapor transmission rate of from 500 to 2000 grams/square meter/24 hours at 37.5.degree. C. and 100% to 10% relative humidity difference. Materials for use in the dressings and processes for manufacture of the dressings are also described.

Abstract: Infant foods suitable for use in the feeding of low birthweight infants, more especially preterm infants, are disclosed. The foods contain a relatively high level of vitamin B.sub.2 and may be prepared so as to have an opacity greater than that of human breast milk leading to less susceptibility of the vitamin B.sub.2 to breakdown by UV-light when used for the feeding of low birthweight infants who are receiving phototherapy. Preferred infant foods according to the invention also have high contents of vitamin B.sub.6, vitamin C, vitamin D, vitamin E, folic acid, copper and zinc while containing no added iron. Another aspect of the invention is the inclusion of taurine and carnitine. One unexpected property of the infant foods according to the invention with high vitamin content is that their use has been found to reduce the incidence of hyperbilirubinaemia in low birthweight infants.

Abstract: An adhesive wound dressing which comprises a flexible polymer film having an adhesive surface and a non-adhesive surface on the opposite side, a removable protector over the adhesive surface and a detachable handle along an edge margin of the polymer film is described. The handle is used to facilitate handling of the film during application of the dressing and is formed from a tearable material so that it can be removed by tearing without disturbing the applied dressing. In a second described embodiment the tearable handle carries an adhesive coating so that the user has the option of removing the handle or adhering it to the skin of the patient.

Abstract: A compound of formula I: ##STR1## or a solvate or salt thereof in which: R is an acyl group containing a substituted or unsubstituted carbocyclic or heterocyclic aromatic ring and R.sub.1 and R.sub.2 are independently C.sub.1-6 alkyl groups or together form a C.sub.3-6 polymethylene or alkenylene group, is useful for treating pain in mammals.

Abstract: The compounds of the formula (II): ##STR1## and their pharmaceutically acceptable salts wherein R.sub.1 is a hydrogen, fluorine or chlorine atom or a hydroxyl, hydroxymethyl, methyl, methoxyl, amino, formamido, acetamido, methylsulphonylamido, nitro, benzyloxy, methylsulphonylmethyl, ureido, trifluoromethyl or p-methoxybenzylamino group; R.sub.2 is a hydrogen, fluorine or chlorine atom or a hydroxyl group; R.sub.3 is a hydrogen or chlorine atom or a hydroxyl group; R.sub.4 is a carboxylic acid group or a salt, ester or amide thereof; R.sub.5 is a hydrogen, chlorine or fluorine atom or a methyl, methoxyl or hydroxyl group or a carboxylic acid group or a salt, ester or amide thereof; R.sub.6 is a hydrogen atom or a methyl, or propyl group; X is an oxygen atom or a bond; and Y is an alkylene group of up to 6 carbon atoms or a bond have been found to possess anti-obesity and/or anti-hyperglycaemic activity.

Abstract: A fibrinolytically active hybrid protein which comprises one chain of a 2-chain protease linked to a chain of a different 2-chain protease, or to the same chain of the same protease, at least one of the chains in the hybrid protein being derived from a fibrinolytically active protease, such that the hybrid protein has a catalytic site essential for fibrinolytic activity which is optionally blocked by a removable blocking group.

Abstract: A robot hand gripping device intended for equipping the end of the wrist or arm of an industrial robot or robotized appliance, comprising grasping members or fingers and hydromechanical controls for spreading the grasping members apart from one another and/or bringing them closer to one another. It is formed by assembling together two identical parts with an intermediate piece between the parts, connectors being provided in the intermediate piece for connecting the two identical parts to at least one drive-energy source, such as compressed air, oil or the like.

Abstract: A compound of the formula (I): ##STR1## in which: is a single bond or a double bond,X is hydrogen or hydroxy,n is 0 or 1,Z is ##STR2## when in ring B is a double bond, and, when in ring B is a single bond, Z is wherein W is hydrogen, lower acyl, unsubstituted arylcarbonyl, lower alkyl or substituted arylcarbonyl.These compounds are useful as platelet aggregation inhibitors.

Abstract: A cross-linked, hydrogel polymer for contact lenses with a water uptake of between 60 and 70% by weight based on the total weight of hydrogel is formed from a mixture of monomer components containing (1) N-vinyl-2-pyrrolidone, (2) alkyl methacrylate and (3) a compound of formula ##STR1## in which R.sup.1 is hydrogen or a lower alkyl group, preferably methyl, and R.sup.2 is either a substituted or unsubstituted aryl group or an alkyl group containing from 1 to 6 carbon atoms substituted by a substituted or unsubstituted aryl group or a substituted or unsubstituted aryloxygroup or by a cycloalkyloxygroup. Preferably the alkyl methacrylate is hydroxyethyl methacrylate and the third component phenethyl methacrylate. Cross-linking agents used preferably have their two functional groups differing in reactivity, for example allyl methacrylate.

Abstract: A surgical dressing which consists essentially of a film which carries an adhesive layer for securing the dressing to the body characterized in that (a) the film is continuous and comprises a polymer which in contact with water has a higher MVP than when in contact with moisture vapor but not water, (b) the adhesive layer is adapted to allow access of water to the film when water is in contact with the adhesive layer so that said surgical dressing has a MVP of not less than 2500 g/m.sup.2 when the adhesive layer is in contact with water and has a MVP of not more than 2000 g/m.sup.2 when the adhesive is in contact with moisture vapor but not water; whereby the dressing is suitable for use on exuding wounds and on non-exuding wounds.

Abstract: Compounds of formula I ##STR1## in which R.sub.1 is C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.3-7 cycloalkyl, cycloalkylalkyl or optionally substituted phenyl; R.sub.2 is H or C.sub.1-3 alkyl; R.sub.3 and/or R.sub.4 are H, formyl, C.sub.1-3 alkyl, C.sub.3-6 alkenyl, C.sub.3-6 alkynyl, C.sub.3-7 cycloalkyl or R.sub.3 and R.sub.4 together with the nitrogen atom form a heterocyclic ring system; R.sub.5 and/or R.sub.6 are H, halo, CF.sub.3, C.sub.1-3 alkyl, C.sub.1-3 alkoxy, C.sub.1-3 alkylthio or R.sub.5 and R.sub.6 together with the carbon atoms to which they are attached form a second benzene ring show therapeutic activity in the treatment of depression. Pharmaceutical compositions and processes for preparing compounds of formula I are disclosed.

Abstract: The present invention provides a heavy-duty, multi-wall or multi-ply bag having gusseted sides and overlapping upper sealing edges of the pinch seal type, wherein a quick-opening construction is provided for such bag. The quick-opening construction consists of (a) a slotted portion formed of one or more slots in the outer wall of the bag, within the gusset and adjacent the upper sealed portion of the bag, and (b) a transverse perforated section on the inner wall or walls (plies) of the bag and disposed substantially intermediate the slots in the outer wall. The outer wall may be torn by fingers engaging the slots, and the inner wall or walls may be penetrated by fingers entering the perforations. The entire upper corner of the bag may be hand opened to provide a funnel for quick delivery of the contents.

Abstract: It has been a problem to combat the liver fluke parasite in ruminant animals such as sheep and cattle. The present invention provides antigens having specificity for the juvenile stage of the organism. They are defined as obtainable from juvenile Fasciola, preferably F. hepatica, organisms by either of two closely related methods. In both methods crude antigen is extracted from juvenile Fasciola organisms and used to raise an antiserum (by injection into rabbits for example). The antiserum is then reacted with adult Fasciola antigens. An adult antigen--adult antibody complex is formed, leaving the other components of the antiserum including juvenile specific antibodies. The juvenile specific antibodies are separated from the complex by spinning and "Millipore" filtering. This is followed either by (1) separating IgG components, including specific IgGs, e.g.

Abstract: An antibacterially active 9,11-O-methylene derivative of 9-dihydroerythromycin wherein the methylene group is optionally substituted by one or two hydrocarbon groups. In particular, compounds of formula I and their pharmaceutically acceptable esters and acid addition salts: ##STR1## wherein: R.sup.1 and R.sup.2 are each H, optionally substituted hydrocarbon, or optionally substituted 5 or 6-membered O or S heterocyclyl, orR.sup.1 +R.sup.2 is optionally substituted divalent hydrocarbon,R.sup.3 is H or OH;R.sup.4 is H, F or OH;R.sup.5 and R.sup.6 are each H of CH.sub.3 ;one of R.sup.7 and R.sup.8 is H, OH, alkoxy, alkanoyloxy optionally substituted NH.sub.2, or R.sup.9 --SO.sub.2 --O--, and the other of R.sup.7 and R.sup.8 is H, orR.sup.7 +R.sup.8 is oxo, oxime or substituted oxime; and R.sup.9 is organic.