Patents Represented by Attorney James L. Rowe

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  • Aryloxyphenylpropylamines for obtaining a psychotropic effect
    Patent number: 4194009
    Abstract: 3-Aryloxy-3-phenylpropylamines and acid additions salts thereof, useful as psychotropic agents, particularly as anti-depressants.
    Type: Grant
    Filed: September 15, 1976
    Date of Patent: March 18, 1980
    Assignee: Eli Lilly and Company
    Inventors: Bryan B. Molloy, Klaus K. Schmiegel
  • Novel oxiodinium and thiaiodinium compounds
    Patent number: 4193935
    Abstract: Novel oxiodinium and thiaiodinium compounds having a superior inhibitory effect against micro-organisms coupled with outstanding stability and low toxicity are described.
    Type: Grant
    Filed: March 2, 1973
    Date of Patent: March 18, 1980
    Assignee: Eli Lilly and Company
    Inventor: William N. Cannon
  • Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
    Patent number: 4191688
    Abstract: C-3 Carboxamides of leurosine, leuroformine, 4-desacetylleurosine and 4-desacetylleuroformine, useful as antitumor agents.
    Type: Grant
    Filed: June 12, 1978
    Date of Patent: March 4, 1980
    Assignee: Eli Lilly and Company
    Inventors: Robert A. Conrad, George J. Cullinan, Jean C. Miller, Koert Gerzon
  • 6-n-Propyl-8-methoxy-methyl or methylmercaptomethylergolines and related compounds as prolactin inhibitors and to treat Parkinson's syndrome
    Patent number: 4180582
    Abstract: 6-n-Propyl (ethyl or allyl)-8.beta.-methoxy-(methyl-sulfinyl, methylsulfonyl, or methylmercapto) methylergolines, 8-ergolenes or 9-ergolenes, useful as prolactin inhibitors and in the treatment of Parkinsonisn.
    Type: Grant
    Filed: January 11, 1979
    Date of Patent: December 25, 1979
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • Process of producing 5'-hydroxyleurosine and related compounds
    Patent number: 4175080
    Abstract: 5'-Hydroxyleurosine, 5'-hydroxyleuroformine and related compounds, useful in inhibiting the growth of experimental tumors.
    Type: Grant
    Filed: August 2, 1978
    Date of Patent: November 20, 1979
    Assignee: Eli Lilly and Company
    Inventors: Gerald L. Thompson, Gloria C. Paschal, Robert A. Conrad
  • 1-Substituted-3-amino-6,7-dialkoxy-1H-1,2,4-benzothiadiazine-1-oxides
    Patent number: 4171361
    Abstract: 1-Substituted-3-amino-6,7-dialkoxy-1H-1,2,4-benzothiadiazine-1-oxides, useful as hypotensive agents.
    Type: Grant
    Filed: March 31, 1977
    Date of Patent: October 16, 1979
    Assignee: Eli Lilly and Company
    Inventors: Robert D. Dillard, Donald E. Pavey
  • N-heterocyclic ureas as immune regulants
    Patent number: 4171364
    Abstract: Benzimidazolyl, benzothiazolyl and benzoxazolyl ureas and thioureas are employed as immune regulatory agents, as agents capable of altering the immune response in mammals.
    Type: Grant
    Filed: November 30, 1978
    Date of Patent: October 16, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, John L. Sands
  • Novel contraceptive method
    Patent number: 4171358
    Abstract: Progestational agents administered daily to female mammals during the follicular phase only of the cycle prevents uterine development associated with implantation in the luteal phase, thereby preventing conception.
    Type: Grant
    Filed: April 19, 1976
    Date of Patent: October 16, 1979
    Assignee: Eli Lilly and Company
    Inventor: Larry J. Black
  • Trifluoromethylphenyl benzyl ethers
    Patent number: 4168388
    Abstract: Trifluoromethylphenols are prepared by hydrogenation of the corresponding trifluoromethylbenzylethers.
    Type: Grant
    Filed: March 23, 1978
    Date of Patent: September 18, 1979
    Assignee: Eli Lilly and Company
    Inventors: Edward R. Lavagnino, Bryan B. Molloy, Paul Pranc
  • Derivatives of 4-desacetyl VLB C-3 carboxyhydrazide
    Patent number: 4166810
    Abstract: N.sup.2 derivatives of 4-desacetyl VLB (vinblastine) C-3 carboxyhydrazide, active anti-tumor agents.
    Type: Grant
    Filed: April 20, 1978
    Date of Patent: September 4, 1979
    Assignee: Eli Lilly and Company
    Inventors: George J. Cullinan, Koert Gerzon
  • 6-N-Propyl-8-methoxymethyl or methylmercaptomethylergolines and related compounds
    Patent number: 4166182
    Abstract: 6-n-Propyl (ethyl or allyl)-8.beta.-methoxy-(methylsulfinyl, methylsulfonyl, or methylmercapto) methylergolines, 8-ergolenes or 9-ergolenes, useful as prolactin inhibitors and in the treatment of Parkinsonism.
    Type: Grant
    Filed: February 8, 1978
    Date of Patent: August 28, 1979
    Assignee: Eli Lilly and Company
    Inventors: Edmund C. Kornfeld, Nicholas J. Bach
  • Vinca alkaloid intermediates
    Patent number: 4160767
    Abstract: 3-Spiro-5"-oxazolidine-2",4"-dione derivatives of Vinca alkaloids, useful as anti-tumor agents and as intermediates.
    Type: Grant
    Filed: August 21, 1978
    Date of Patent: July 10, 1979
    Assignee: Eli Lilly and Company
    Inventors: Jean C. Miller, Gerald E. Gutowski
  • Preparation of oxazolidinedione derivatives of Vinca alkaloids
    Patent number: 4159269
    Abstract: 3-Spiro-5"-oxazolidine-2",4"-dione derivatives of Vinca alkaloids, useful as anti-tumor agents, synthesized from a C-3 carboxamide and a dialkyl carbonate.
    Type: Grant
    Filed: March 3, 1978
    Date of Patent: June 26, 1979
    Assignee: Eli Lilly and Company
    Inventor: Jean C. Miller
  • Substituted 2,3-dihydro imidazo[1,2-c]pyrimidines
    Patent number: 4153695
    Abstract: Di-substituted 2,3-dihydroimidazo[1,2-c]pyrimidines, useful as anti-viral agents.
    Type: Grant
    Filed: March 9, 1978
    Date of Patent: May 8, 1979
    Assignee: Eli Lilly and Company
    Inventor: William W. Turner
  • N-Heterocyclic ureas as immune regulants
    Patent number: 4153709
    Abstract: Benzimidazolyl, benzothiazolyl and benzoxazolyl ureas and thioureas are employed as immune regulatory agents, as agents capable of altering the immune response in mammals.
    Type: Grant
    Filed: October 20, 1977
    Date of Patent: May 8, 1979
    Assignee: Eli Lilly and Company
    Inventors: Charles J. Paget, John L. Sands
  • 4'-Deoxyvincristine and related compounds
    Patent number: 4143041
    Abstract: 4'-Deoxyvincristine, 4'-deoxy-1-formylleurosidine and the corresponding 4-desacetyl derivatives, useful in inhibiting the growth of experimental tumors.
    Type: Grant
    Filed: November 25, 1977
    Date of Patent: March 6, 1979
    Assignee: Eli Lilly and Company
    Inventor: Gerald L. Thompson
  • Ketone derivatives
    Patent number: 4141995
    Abstract: o-Hydroxybenzophenones and derivatives thereof are described together with a process for their production. The compounds have anti-allergy activity and are characterized by the presence of an alkyl substituent on the hydroxyphenyl ring.
    Type: Grant
    Filed: September 2, 1977
    Date of Patent: February 27, 1979
    Assignee: Lilly Industries Limited
    Inventors: John C. Saunders, William R. N. Williamson
  • Substituted pyrroloquinoxalinones and diones used in treating inflammation in warm blooded mammals
    Patent number: 4133884
    Abstract: Substituted pyrroloquinoxalinones and diones, useful as anti-inflammatory and anti-thrombotic agents.
    Type: Grant
    Filed: December 12, 1977
    Date of Patent: January 9, 1979
    Assignee: Eli Lilly and Company
    Inventor: Richard E. Holmes
  • 8,8-Disubstituted-6-methylergolines and related compounds
    Patent number: RE30218
    Abstract: 8,8-Disubstituted-6-methylergolines and 9-ergolenes, prepared by alkylation of lysergic, isolysergic or their 9,10-dihydro analogues, optionally followed by chemical modification of an 8-substituent.
    Type: Grant
    Filed: February 12, 1979
    Date of Patent: February 19, 1980
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld
  • Method of preparing 8,8-disubstituted-6-methylergolines and related compounds
    Patent number: RE30219
    Abstract: 8,8-Disubstituted-6-methylergolines and 9-ergolenes, are prepared by alkylation of lysergic, or isolysergic acid or their 9,10-dihydro analogues.
    Type: Grant
    Filed: February 5, 1979
    Date of Patent: February 19, 1980
    Assignee: Eli Lilly and Company
    Inventors: Nicholas J. Bach, Edmund C. Kornfeld