Abstract: A system and method of separation of therapeutic components from blood. The system includes a dual member centrifuge and a disposable single use fluid transfer set. The set includes an elongated flexible separation chamber having an input port, a separated component output port and a residual fluid output port. The input port and the separated component output ports are located at opposite ends of the elongated separation chamber. The centrifuge includes a receiving chamber with a selectively formed annular slot therein. The separation chamber is positioned in the annularly shaped slot and rotated at a predetermined rotational velocity. Fluids such as whole blood flows through the separation chamber and are separated into various therapeutic components such as platelet rich plasma and residual concentrated red blood cells. Platelet rich plasma can be drawn off as the separated therapeutic component. An alternate two part transfer set provides for highly efficient platelet pheresis.

Abstract: A peristaltic pump includes a pump race for receiving a flexible tubing. A rotatable pump rotor carries at least one roller for contacting the tubing. A roller locating mechanism moves the pump roller between a retracted position free of contact with the tubing and an extended position making operative contact with the tubing. A controller operates the pump (i) in a pumping mode, during which the rotor is rotated with the roller located in its extended position, and (ii) in a valving mode, during which rotation of the rotor is terminated and the roller is selectively moved between its extended position to block fluid flow through the tubing and its retracted position to permit fluid flow through the tubing. The pump thus provides a peristaltic pump pumping function, as well as serving as a valve element.

Abstract: A peristaltic pumping apparatus includes a peristaltic pump rotor and pump race. A pump tube cassette includes a body for supporting a flexible tubing loop in an erect, outwardly bowed position for placement within the pump race and for removal from the pump race. A surface juxtaposed the peristaltic pump rotor and race carries a gripping jaw assembly. The gripping jaw assembly opens to receive the pump tube cassette body as the body is moved toward the pump rotor to place the tubing loop within the pump race. The gripping jaw assembly closes to secure the pump tube holder body on the surface in an orientation in which the tubing loop lies within the pump race for engagement with the peristaltic pump rotor.

Abstract: A cassette serves in association with one or more peristaltic pumps to centralize pumping, valving, and pressure sensing functions. The cassette includes a housing having first and second pump ports. A flexible tubing loop extends between the first and second pump ports outside the housing for engagement with an external peristaltic pump element. A liquid port on the housing attaches to a length of tubing that also extends outside the housing. Liquid passages within the housing that establish communication among the liquid port, the first pump port, and the second pump port. Valve stations formed within the housing are responsive to the application of external force for controlling liquid flow through the liquid passages. A sensing chamber is formed within the housing along at least one liquid passage. The sensing chamber transmits information regarding liquid pressure present within the one liquid passage to an external sensing element.

Abstract: A peristaltic pump has a pump rotor rotatable about an axis. The pump rotor carries a pump roller. An actuating rod extends along the axis of rotation. The rod has a distal end and a proximal end. An actuator mechanism is coupled to the proximal rod end for advancing the rod along the axis of rotation in a forward direction toward the pump rotor and in a rearward direction away from the pump rotor. A linkage mechanism is coupled to the distal rod end for converting advancement of the actuating rod along the axis of rotation in response to the actuator mechanism into movement of the pump roller radially of the axis of rotation between a retracted position free of contact with pump tubing and an extended position making operative contact with pump tubing.

Abstract: The present invention provides a coextruded tubing that has been optimized for usage in cryogenic freezing applications. To this end, a coextruded tubing is provided having three layers, a first layer of ethylene vinyl acetate; a second layer of polyolefin; and a third layer of polyvinyl chloride. An improved container for use in cryogenic freezing applications is also provided.

Abstract: A disposable set for a blood processing device comprises an array of flexible tubing and a frame that holds the flexible tubing array with at least two linear segments of the flexible tubing array presented for alignment with at least two axially aligned peristaltic pump rotors.

Abstract: A self-loading peristaltic pumping apparatus includes a pump race for receiving a tubing loop, a pump rotor carrying a roller, and a drive mechanism for rotating the rotor within the pump race. The apparatus also includes a roller locating mechanism that moves the pump roller between a retracted position, free of contact with the received tubing loop, and an extended position, at least partially within the pump race for operative contact with the received tubing loop. The apparatus includes at least one tubing guide element carried by the rotor. The guide element extends from the rotor at least partially into the pump race. The guide element serves during rotation of the rotor with the roller in its retracted position, for contacting the received tubing loop to orient the tubing loop within the pump race.

Abstract: A compact pump assembly includes a plurality of axially aligned peristaltic pumps for activating the flow of liquids through the conduits. A housing containing the pumps, is provided with a removable cover for retaining the pumps in the housing when the cover is closed and for permitting removal of the pumps when the cover is opened. A reversible motor is mounted outside of the housing for driving each of the pumps. The pumps may be independently inactivated by an individual release mechanisms provided on the common closure cover.

Abstract: A peristaltic pump tube holder has a body having first and second pump tube connectors extending outside of it. The pump tube connectors extend at an acute angle relative to a surface of the body to receive a flexible tubing loop and orient the tubing loop for engagement with an external peristaltic pump rotor.

Abstract: Diallyl dimethyl ammonium chloride/3-acrylamido-3-methyl-butanoic acid copolymers were prepared and found to be effective pitch control agents in papermaking systems.

Abstract: A secondary polishing process for Bayer Process liquors suspension is described. The polishing process uses a combination of bio-polymers, particularly such bio-carbohydrates as dextran, with an inert insoluble solid, such as a filter aid, to treat the primary red mud settler overflow, then clarifying these treated overflow liquors in a secondary clarifier. Results provide for from 0-20 milligrams per liter suspended solids, often from 0-5 ppm suspended solids, and may make sand filter or Kelly filter operation an option in the Bayer Process.

Abstract: The invention provides a method for manufacturing tissue paper. According to the method, a yankee dryer adhesive composition is applied to a metal surface of a drying drum. The yankee dryer adhesive composition preferably includes from about 1 to about 100 mole percent vinylamine and from about 1 to about 99 of at least one monomer selected from the group consisting of vinylformamide, vinyl acetate and vinyl alcohol. The yankee dryer adhesive composition is contacted with a continuous paper web. The continuous paper web is then dried. The dry continuous paper web is creped with a metal blade to form tissue paper.

Abstract: The product selection test is developed for rapid determination of the presence of synergistic blends of the biocide or the presence of biocide blends in contaminated waters. The method uses a reduction oxidation dye system, supplied nutrients, admixtures of one or more biocides or blends thereof and incubation times and temperatures providing for a variation of color changes of the dye system. Industrial waters such as pulp and paper waters contaminated with microbes can be tested by this rapid method of determining the presence of synergistic blends of anti-microbial agents.

Abstract: The present invention contemplates a hot mill lubricant composition capable of use in demanding hot steel rolling mill operations wherein the composition comprises a synthetic base carrier composition comprising a mixture of dimeric and polymeric esters formed between saturated and unsaturated fatty acids with up to 18 carbon atoms, and various alcohols and polyols, said composition having a molecular weight between 500 and 1000 daltons (da). In addition to providing superior lubrication compatible with mill operations at elevated temperatures, the composition of the present invention provides additional advantages such as superior breakout and plateout characteristics.

Abstract: A method for the determination of organic hydroperoxides in a hydrocarbon which has been subjected to oxidative polymerization conditions is disclosed. The steps employed in the invention include mixing an organic cupric salt such as cupric acetate and a phenanthroline such as 2,9-dimethyl-1,10-phenanthroline with a sample of the hydrocarbon in an organic solvent such as acetonitrile, measuring the color change after a fixed period of time for cuprous complex formation, and comparing the measurement to the color change of a standard reference to determine the relative quantity of organic hydroperoxide in the sample.

Abstract: A composition suitable for use as a binder of ceramic materials and a method for preparing a ceramic material which provides relatively greater green ceramic strength is disclosed. The improved binder contains a substantially hydrolyzed copolymer made from monomers having ester or amide functional groups, poly(vinyl amine), poly(vinyl formamide) or a copolymer of vinyl alcohol and vinyl amine. The binder is combined with an aqueous solution containing a ceramic powder to make a slurry, and the slurry is subsequently spray dried, pressed and heated to make a ceramic.

Abstract: Red mud is flocculated from Bayer process liquors using a polymer which contains vinylamine and/or vinylformamide.

Abstract: A method for defoaming a Bayer process liquor, the method comprising the steps of adding to the Bayer process liquor an effective amount of an antifoam/defoamer composition comprising a polyether surfactant and a polyhydric alcohol fatty acid ester.