Patents Represented by Attorney Julian S. Levitt

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  • Coatings for ferrous substrates
    Patent number: 3956030
    Abstract: Coatings for silicon steel comprised of MgO, an amorphous magnesia-silica complex and a boron bearing compound.
    Type: Grant
    Filed: June 27, 1975
    Date of Patent: May 11, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Howard M. Siegel, Samuel W. Sopp
  • 3-Fluoro-D-alanine and pharmacologically acceptable esters, and pharmacologically acceptable salts thereof
    Patent number: 3956367
    Abstract: 3-Fluoro-D-alanine, its pharmacologically acceptable esters, and pharmacologically acceptable salts of the foregoing, as well as other pharmacologically acceptable derivatives of 3-fluoro-D-alanine which, when administered clinically, are effective in releasing 3-fluoro-D-alanine in vivo, are potent antibacterial agents, and are prepared by fluorination of D-alanine with fluoroxyperfluoroalkanes or fluoroxypentasulfur in the presence of a free radical initiator followed by esterification and/or treatment with acids or bases.
    Type: Grant
    Filed: August 5, 1974
    Date of Patent: May 11, 1976
    Assignee: Merck & Co., Inc.
    Inventor: Janos Kollonitsch
  • Processes for asymmetric conversion of 3-fluoro-L-alanine and 2-deutero-3-fluoro-L-alanine to their D-isomers
    Patent number: 3950411
    Abstract: 3-Fluoro-L-alanine is transformed by asymmetric conversion, via an intermediate L-2-(halo)-3-fluoropropionic acid, to 3-fluoro-D-alanine. The 3-fluoro-D-alanine thus obtained is a potent antibacterial agent.
    Type: Grant
    Filed: February 24, 1975
    Date of Patent: April 13, 1976
    Assignee: Merck & Co., Inc.
    Inventor: Donald F. Reinhold
  • Antibiotics
    Patent number: 3950357
    Abstract: The antibiotic thienamycin is active against both gram-positive and gram-negative bacteria. The antibiotic is produced by growing a newly-found and hitherto undescribed species of Streptomyces on suitable fermentation media.
    Type: Grant
    Filed: November 25, 1974
    Date of Patent: April 13, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Jean S. Kahan, Frederick M. Kahan, Edward O. Stapley, Robert T. Goegelman, Sebastian Hernandez
  • 3-.alpha.-Substituted cephalosporins
    Patent number: 3947413
    Abstract: Novel cephalosporin compounds having a 3'-.alpha.-methyl, a 3-aryl or 3-heterocycle substituent are prepared by total synthesis. The novel cephalosporin compounds are active against gram-negative and gram-positive microorganisms.
    Type: Grant
    Filed: August 27, 1973
    Date of Patent: March 30, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Burton G. Christensen, Ronald W. Ratcliffe
  • Coated ferrous substrates comprising an amorphous magnesia-silica complex
    Patent number: 3945862
    Abstract: Coatings for silicon steel comprised of MgO, an amorphous magnesia-silica complex and a boron bearing compound.
    Type: Grant
    Filed: November 15, 1974
    Date of Patent: March 23, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Howard M. Siegel, Samuel W. Sopp
  • Coatings for ferrous substrates
    Patent number: 3941622
    Abstract: Novel amorphous magnesia-silica complexes containing from about 0.001 to 2.0 percent by weight of an alkali metal oxide, wherein the mole ratio of MgO:SiO.sub.2 of said complexes is from about 1:25 to 14:1.
    Type: Grant
    Filed: April 21, 1975
    Date of Patent: March 2, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Yoshio Uyeda, Samuel W. Sopp
  • Coatings for ferrous substrates
    Patent number: 3941621
    Abstract: Coatings for silicon steel comprised of MgO, an amorphous magnesia-silica complex and a lithium bearing compound.
    Type: Grant
    Filed: April 21, 1975
    Date of Patent: March 2, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Samuel W. Sopp, Howard M. Siegel
  • Magnesia coatings for ferrous substrates comprising amorphous magnesia-silica complexes
    Patent number: 3932203
    Abstract: Novel amorphous magnesia-silica complexes containing from about 0.001 to 2.0 percent by weight of an alkali metal oxide, wherein the mole ratio of MgO:SiO.sub.2 of said complexes is from about 1:25 to 14:1.
    Type: Grant
    Filed: October 7, 1974
    Date of Patent: January 13, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Yoshio Uyeda, Samuel W. Sopp
  • Magnesia coatings for ferrous substrates comprising amorphous magnesia-silica complexes
    Patent number: 3932202
    Abstract: Coatings for silicon steel comprised of MgO, an amorphous magnesia-silica complex and a lithium bearing compound.
    Type: Grant
    Filed: November 5, 1974
    Date of Patent: January 13, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Leonard S. Lee, Samuel W. Sopp, Howard M. Siegel
  • Probenecidoxymethyl and 1-ethyl esters of ampicillin
    Patent number: 3931150
    Abstract: New ampicillin derivatives, probenecidoxymethyl and 1-ethyl esters of ampicillin and their pharmaceutically acceptable salts, useful as antibiotics. A method for preparing these antibiotics by condensing probenecidoxymethyl or 1-ethyl halide with an acid salt of 6[D(-)-.alpha.-azidophenylacetamido] penicillanic acid, hydrogenating the azido group and isolating the product as a pharmaceutically acceptable salt of an acid. Pharmaceutical preparations containing the new antibiotics.
    Type: Grant
    Filed: July 30, 1974
    Date of Patent: January 6, 1976
    Assignee: Merck & Co., Inc.
    Inventors: Burton G. Christensen, William J. Leanza