Patents Represented by Attorney King & Spalding, LLP
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Patent number: 8016811Abstract: A method for delivering permeant substances transdermally into a membrane of an animal includes forming at least one delivery opening in the skin tissue, with the at least one delivery opening having a mean opening depth of between about 40 and about 90 microns.Type: GrantFiled: October 24, 2003Date of Patent: September 13, 2011Assignee: Altea Therapeutics CorporationInventors: Alan Smith, Jonathan A. Eppstein, Bernadette Messier, Zoran Novakovic, Stuart McRae
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Patent number: 8012975Abstract: Antitumor compounds have the five membered fused ring ecteinascidin structure of the formula (XIV). The present compounds lack a 1,4-bridging group as found in the ecteinascidins. They have at the C-1 position a substituent selected from an optionally protected or derivatised aminomethylene group or an optionally protected or derivatised hydroxymethylene group.Type: GrantFiled: December 22, 2006Date of Patent: September 6, 2011Assignee: Pharma Mar, S.A.Inventors: Ignacio Manzanares, Carmen Cuevas, Marta Perez, Maria Jesus Martin, Alberto Rodriguez, Simon Munt
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Patent number: 8014859Abstract: An external defibrillator enclosure for use in conjunction with a defibrillator accessory, such as an electrode pad assembly, includes a front panel and a rear panel which are mated together and secured by a coupling means. The enclosure also includes a plate secured by a coupling means to the second panel. The plate and second panel are positioned relative to each other to form a slot that is sized to receive a portion of the electrode assembly. The enclosure also includes a connector port that allows for the electrode pad assembly to be pre-connected to the electronics within the enclosure. The electrode pad assembly includes a cable and a connector at the end of the cable, and the exterior face of enclosure rear panel includes a groove that is sized to receive and retain the cable. The groove holds the cable in place against the surface of the enclosure while the cable is connected to the connector port.Type: GrantFiled: October 2, 2003Date of Patent: September 6, 2011Assignee: Defibtech, LLCInventors: Gintaras A. Vaisnys, Glenn W. Laub, Giovanni C. Meier, Benny S. Chi, James Sener
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Patent number: 8012468Abstract: The present invention relates to an antitumor immune response, and in more detail, to a method for inducing cytotoxic T lymphocytes specific to a tumor-associated antigen that acts specifically on tumor cells. Immunotherapy using the present invention may be most effective among immune therapies that use immunity of our body, because in the present invention, CEA-specific cytotoxic T lymphocytes can be induced in vitro by using a dendritic cell transduced with a recombinant adenovirus. Further, immunotherapy using the present invention can function as a powerful tool for tumor prevention or treatment, if being used in combination with antitumor vaccines or other treatments.Type: GrantFiled: June 11, 2004Date of Patent: September 6, 2011Assignee: Catholic Universtiy Industry Academic Cooperation FoundationInventors: Tai-gyu Kim, Hyun-il Cho, Hye-jin Kim, Seoug-taek Oh
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Patent number: 8013140Abstract: It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.Type: GrantFiled: August 21, 2008Date of Patent: September 6, 2011Assignee: The Resarch Foundation for Microbial Diseases of Osaka UniverstiyInventors: Masaya Takemoto, Yasuko Mori, Koichi Yamanishi, Isao Fuke, Yasuyuki Gomi, Michiaki Takahashi
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Patent number: 8014888Abstract: A design module is a software module that is implemented in a computer system that comprises instructions stored in a machine-readable medium and a processor that executes the instructions. The design module receives inputs from a person to create a custom insert for a lighting control panel. The inputs identify the content and locations of labels and a decorative background of the insert. Each label is associated with a corresponding input device. Each input device is associated with an optical configuration or “scene” of an environment associated with the lighting control panel. Each label includes alphanumeric text and/or graphics that identify the scene of the label's corresponding input device. The design module causes the insert to be generated by instructing a printer to print the labels and background on a sheet of material, at the specified locations.Type: GrantFiled: May 11, 2009Date of Patent: September 6, 2011Assignee: Cooper Technologies CompanyInventor: Louis della-Porta
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Patent number: 8013139Abstract: It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.Type: GrantFiled: August 21, 2008Date of Patent: September 6, 2011Assignee: The Research Foundation for Microbial Diseases of Osaka UniversityInventors: Masaya Takemoto, Yasuko Mori, Koichi Yamanishi, Isao Fuke, Yasuyuki Gomi, Michiaki Takahashi
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Patent number: 8013263Abstract: A transformer switch, such as a multi-deck tap changer, includes an assembly with a first housing coupled to a first cover. The first cover holds at least a first stationary electric contact. A second housing is formed integrally with the first cover, and is coupled to a second cover, the second cover holding at least a second stationary electric contact. The first housing and first cover together define a first interior volume within which the first stationary electric contact is disposed. The second cover and the second housing together define a second interior volume within which the second stationary electric contact is disposed. Each housing-cover coupled pair includes an interior rotor rotatable relative to the stationary electric contact in the cover of the pair. At least one movable contact is coupled to each rotor. The covers and housings can be molded from a non-conductive plastic.Type: GrantFiled: June 3, 2009Date of Patent: September 6, 2011Assignee: Cooper Technologies CompanyInventor: Kurt Lawrence Lindsey
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Patent number: 8015182Abstract: A system for appending security information to search engine results, including a search engine for locating, in a computer network, web pages that include at least one designated search term, for issuing a security analysis request to a content security scanner to assess at least one designated web page for potential security risks, and for preparing a search results summary that includes links to the located web pages and security assessments for the located web pages, a client computer communicatively coupled with the search engine for issuing a search request with at least one user designated search term, to the search engine, and for receiving the search results summary from the search engine, and a content security scanner communicatively coupled with the search engine for assessing security of content in at least one designated web page. A method and computer-readable storage media are also described and claimed.Type: GrantFiled: November 29, 2006Date of Patent: September 6, 2011Assignee: Finjan, Inc.Inventors: Ben-Itzhak Yuval, Elbaz Limor
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Patent number: 8011013Abstract: A method for limiting devices and controlling the applications executed from USB ports on personal computers (PCs). More specifically, the present invention relates to a method for ensuring that only authorized devices and applications are accessed from USB ports using software and configuration files on the PC. Using the software application stored on the PC storage device in conjunction with functionality performed by a designed security file server, the use of USB applications and devices is limited to authorized applications and devices.Type: GrantFiled: July 16, 2007Date of Patent: August 30, 2011Assignee: QuickVault, Inc.Inventor: Steven V. Bacastow
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Patent number: 8010470Abstract: A computer-implemented method of behavior prediction includes selecting behavior examples having corresponding antecedent candidates, identifying source text descriptions describing the behavior examples, automatically extracting predictors as common themes across all statements and all behavior examples with a language-independent theme extraction process, flagging each behavior example to indicate a presence or absence of the corresponding extracted antecedents in each of the source text descriptions and creating a data array consisting of antecedent columns and behavior example rows, submitting the data array to a pattern classifier to extract patterns among the antecedent candidates and outcomes by training and validating the pattern classifier and predicting a new occurrence of a target behavior by entering a current state of the antecedents to the trained pattern classifier.Type: GrantFiled: November 24, 2009Date of Patent: August 30, 2011Assignee: Science Applications International CorporationInventor: Gary M. Jackson
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Patent number: 8008617Abstract: Ions carried in a flowing gas stream are transferred to another gas stream of different composition or purity through an ion selective aperture communicating between the gas streams. The ion selective aperture is formed of a central layer which has an electrically conductive layer on each of its surfaces. One or more open channels extend through the central layer and surface layers allowing physical movement of ions therethrough under the urging and influence of an electric field created by imposing a voltage differential between the conductive surface layers of the ion selective aperture. The gas flow rates of the different gas streams may be independently varied to allow adjustment of ion concentration and flow rate to meet the needs of the ion destination. This device can control sample ion introduction into gas-phase ion detectors, such as ion mobility analyzers, differential mobility analyzers, mass spectrometers, and combinations thereof.Type: GrantFiled: December 29, 2008Date of Patent: August 30, 2011Assignee: Science Applications International CorporationInventors: John C. Berends, Jr., Timothy P. Karpetsky, Ross C. Willoughby, Edward W. Sheehan
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Patent number: 8008467Abstract: It is intended to provide a promoter for inducing expression selectively and strongly in an immunocompetent cell and/or a blood cell such as a lymphocyte. In the invention, the object was achieved by finding that HHV6 MIE promoter, HHV7 MIE promoter and HHV7 U95 promoter unexpectedly induce a specific expression in an immunocompetent cell and/or a blood cell such as a T lymphocyte. By utilizing the promoters, a selective delivery of a DNA vaccine or the like can be realized.Type: GrantFiled: September 5, 2006Date of Patent: August 30, 2011Assignee: The Research Foundation for Microbial Diseases of Osaka UniversityInventors: Masaya Takemoto, Yasuko Mori, Koichi Yamanishi, Isao Fuke, Yasuyuki Gomi, Michiaki Takahashi
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Patent number: 8004377Abstract: A fault interrupter and load break switch includes a trip assembly configured to automatically open a transformer circuit electrically coupled to stationary contacts of the switch upon the occurrence of a fault condition. The fault condition causes a Curie metal element electrically coupled to at least one of the stationary contacts to release a magnetic latch. The release causes a trip rotor of the trip assembly to rotate a rotor assembly. This rotation causes ends of a movable contact of the rotor assembly to electrically disengage the stationary contacts, thereby opening the circuit. The switch also includes a handle for manually opening and closing the electrical circuit in fault and non-fault conditions. Actuation of the handle coupled to the rotor assembly via a spring-loaded rotor causes the movable contact ends to selectively engage or disengage the stationary contacts.Type: GrantFiled: May 8, 2008Date of Patent: August 23, 2011Assignee: Cooper Technologies CompanyInventors: Nicholas Brusky, Kurt Lawrence Lindsey
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Patent number: 8001876Abstract: Systems and methods described herein for aligning a block in a microtome attempt to save time, money, and the sample by aligning a block in any rotary or cryostat microtome. One such device for aligning a block in a microtome has a knife holder component removably attached to a knife holder of the microtome and a pin alignment component extending vertically from the knife holder component in a direction substantially parallel to the block. The pin alignment component has a plurality of front pins extending from a front surface of the pin alignment component configured to slide in response to an angle of the block and a plurality of rear pins extending from a rear surface of the pin alignment component and coupled to the front pins. The rear pins are configured to indicate the extension of the front pins from the pin alignment component.Type: GrantFiled: May 14, 2008Date of Patent: August 23, 2011Assignee: SAIC-Frederick, Inc.Inventors: Brian Carroll Tabb, Keith Rogers
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Patent number: 8006243Abstract: A method and apparatus for remote installation of network drivers and software. The present invention provides for the remote installation of a rerouting driver into the network driver interface in the path between one or more media access control units and one or more protocol drivers in a computer system. Code in the network driver interface is disabled, patched to insert the rerouting driver, and then re-enabled. The disabling and re-enabling of the code is performed such that the computer system does not have to be restarted following installation of the patch.Type: GrantFiled: December 19, 2006Date of Patent: August 23, 2011Assignee: International Business Machines CorporationInventor: Clinton Edward Lum
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Patent number: 8006006Abstract: Systems and methods for aggregating transmit completion interrupts for multiple packets are provided. A network device can include a buffer with multiple memory locations capable of temporarily storing a packet being transmitted across the network via the network device and nodes connected to the network device. The network device can include a high watermark for determining when to process transmit completion interrupts. If the number of packets stored in the memory exceeds the high watermark, an aggregated transmit completion interrupt for all of the packets can be processed. Otherwise, the network device waits until sufficient packets are received to reach the high watermark.Type: GrantFiled: June 19, 2008Date of Patent: August 23, 2011Assignee: International Business Machines CorporationInventor: Xiuling Ma
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Patent number: 7997757Abstract: A luminaire with signage endcaps includes a luminaire housing and one or more light emitting elements. The housing typically includes a top member and multiple side members extending down from the top member. The top and side members define the interior of the luminaire housing. Light emitting elements are coupled to the housing. These light emitting elements generally emit light downward from the luminaire and can be coupled along the interior of the housing or positioned along an exterior side of one or more of the side members. A stencil or stencil plate can be positioned along or coupled to one or more others side members. The stencil and stencil plate include openings in the shape of alphanumeric symbols and/or ideograms and include within the openings or have positioned adjacent to the openings a translucent member. Ambient light within the interior of the housing illuminates the stencil and translucent member.Type: GrantFiled: June 13, 2008Date of Patent: August 16, 2011Assignee: Cooper Technologies CompanyInventor: Ellis W. Patrick
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Patent number: 7998696Abstract: A method and kit for assaying a cell sample for the presence of at least a threshold number of cells of a given type are disclosed. The kit includes an assay device having a sample chamber for receiving the cell sample and an elongate collection chamber containing a selected-density and/or viscosity medium and having along its length, a plurality of cell-collection regions, and particles which are capable of specific attachment to cells of the selected cell type, and which are effective, when attached to the cells, to increase the density or magnetic susceptibility of the cells. In operation, particle-bound cells and particles in the cell sample are drawn through the elongate collection chamber under the influence of a gravitational or selected centrifugal or magnetic-field force until the particle-bound cells and particles completely fill successive cell-collection regions in the collection chamber.Type: GrantFiled: December 5, 2008Date of Patent: August 16, 2011Assignee: Zyomyx, Inc.Inventors: Frank Zaugg, Renee Tobias, Silvia McManus-Munoz, Peter Kernen, Laurence Ruiz-Taylor, Peter Wagner
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Patent number: D643374Type: GrantFiled: November 17, 2010Date of Patent: August 16, 2011Assignee: Cooper Crouse-Hinds GmbHInventors: Reiner Naumann, Markus Reinhart, Frank Hieronymus