Abstract: A soft chemical ionization source can be small, require low power, reliably produce different ions depending on the operating conditions and configuration, and produce ions that ionize many sample chemicals in different phases in air, or solutions, or on surfaces. In one embodiment, an ionization source is comprised of a housing having a center post extending therefrom, a plurality of needles extending from the housing, and a counterelectrode extending around the housing. The plurality of needles and the counterelectrode are each coupled to an electrical supply. The center post and the plurality of needles extend through the counterelectrode. A voltage applied to the plurality of needles and the counterelectrode forms a gas discharge. By changing the dimensional or electrical characteristics of the ionization source elements, singularly, or relative to other sources in an array, the types, ratios among, and quantities of reagent ions can be changed and controlled.

Abstract: The invention provides a faulted circuit indicator apparatus with transmission line state display, as well as methods for using the apparatus. The faulted circuit indicator has a sensor that can be electrically coupled to an electrical conductor for collecting data relating to a state of the electrical conductor. The faulted circuit indicator also has a controller that is logically coupled to the sensor for receiving data and determining whether a fault condition has occurred on the electrical conductor. The faulted circuit indicator also has one or more indicators that are logically coupled to the controller for indicating whether a fault condition has occurred as well as the state of the electrical conductor. The state of the conductor may be the voltage, the temperature, or the vibration present on the conductor.

Abstract: The present invention is to obtain a novel gene that encodes a protein having a function of promoting acetic acid bacterial growth in the presence of a high concentration of acetic acid; to enhance acetic acid bacteria's function of promoting growth and thereby to develop acetic acid bacteria with an improved fermentation ability in the presence of a high concentration of acetic acid; and to provide a method for efficiently producing vinegar that contains a high concentration of acetic acid in a short time using the acetic acid bacterium.

Abstract: Methods and compositions for the treatment of intestinal disorders, such as IBD and Crohn's disease, are disclosed. Preferred compositions include siNA. Also disclosed is a method of specifically targeting siNA to treat intestinal disorders by intrarectal administration of siNA compounds.

Abstract: The disclosed invention relates to methods of modifying peptide compositions to increase stability and delivery efficiency. Specifically, the disclosed invention relates to methods to increase the stability and delivery efficiency of protein kinase C (PKC) modulatory peptide compositions. A “therapeutic peptide composition” comprises a “carrier peptide” and a “cargo peptide.” A “carrier peptide” is a peptide or amino acid sequence within a peptide that facilitates the cellular uptake of the therapeutic peptide composition. The “cargo peptide” is a PKC modulatory peptide. Peptide modifications to either the carrier peptide, the cargo peptide, or both, which are described herein increase the stability and delivery efficiency of therapeutic peptide compositions by reducing disulfide bond exchange, physical stability, reducing proteolytic degradation, and increasing efficiency of cellular uptake.

Abstract: A luminaire system provides for mounting and accessing a light fixture housing without tools. A universal bracket is coupled to the junction box along the ceiling and engages with a top mounting plate affixed to the housing. One or more slide hooks appended to the universal bracket allows the top mounting plate to mount to the universal bracket, and a reinforced spring and locking spring keeps the light fixture housing in place, while preventing rattling between the universal bracket and the top-mounting plate. The housing can be removed from the electrical junction box through the use of a release button affixed to the housing. The button disengages the locking spring from the top mounting plate, thereby allowing the housing to swivel away from the universal bracket and junction box by way of a hanging hook. The hanging hook supports the housing when released from the universal bracket.

Abstract: Recombinant adeno-associated viral (AAV) capsid proteins are provided. Methods for generating the recombinant adeno-associated viral capsid proteins and a library from which the capsids are selected are also provided.

Abstract: The present invention relates to the use of Collismycin and derivatives thereof as inhibitors of oxidative stress in cells and their use for the preparation of medicaments for the treatment of oxidative stress-induced diseases or conditions, especially neurodegenerative diseases, such as Alzheimer's Disease and Parkinson's Disease.

Abstract: An apparatus and method for manufacturing a down hole tool that reduces manufacturing costs and enhances the tool's performance. A belted mold assembly includes a casting assembly, a belt assembly, and a mid-belt. The belted mold assembly is used to fabricate a casting that allows for a larger diameter blank to be used which displaces the more expensive casting material and for using a smaller outer diameter thin-walled mold. The casting assembly is disposed within the belt assembly and the mid-belt is loaded in the volume created between the casting assembly's outer surface and the belt assembly's inner surface. The mid-belt provides a bracing for the casting assembly during the casting process. Optionally, a cap can be disposed on top of the blank for preventing metallurgical bonds from forming between the binder material and the upper portion of the blank. This allows for the excess binder material to remain high in purity so that it can be reprocessed.

Abstract: A communications interface accessory for an electric power system arrester is described. The communications interface accessory includes a housing and a communications interface positioned within the housing. The communications interface is configured to complete a signal path with the arrestor. The communications interface accessory also includes a disconnect device positioned within the housing, whereby the disconnect device is coupled to the arrestor and the communications interface.

Abstract: An apparatus and method for manufacturing a down hole tool that reduces manufacturing costs and enhances the tool's performance. A belted mold assembly includes a casting assembly, a belt assembly, and a mid-belt. The belted mold assembly is used to fabricate a casting that allows for a larger diameter blank to be used which displaces the more expensive casting material and for using a smaller outer diameter thin-walled mold. The casting assembly is disposed within the belt assembly and the mid-belt is loaded in the volume created between the casting assembly's outer surface and the belt assembly's inner surface. The mid-belt provides a bracing for the casting assembly during the casting process. Optionally, a cap can be disposed on top of the blank for preventing metallurgical bonds from forming between the binder material and the upper portion of the blank. This allows for the excess binder material to remain high in purity so that it can be reprocessed.

Abstract: The present invention is directed to compounds, compositions thereof, and the use of the compounds and compositions for the treatment and prevention of breast cancer. In one embodiment, the present invention relates to the use of a substituted triphenyl butene or prodrug thereof for the treatment of breast cancer in mono-therapy or in combination therapy, or for a reduction in the recurrence rate of previously-treated breast cancer.

Abstract: A dual interface separable insulated connector comprising a faraday cage molded over a bus bar for use in an electric power system and a method of manufacturing the same are provided. The faraday cage can be disposed within a semi-conductive shell. The configuration of the separable insulated connector can provide for easier bonding between the faraday cage and insulating material. Additionally, the configuration can eliminate or reduce the need to coat the bus bar with an adhesive agent and to smooth the metal bus bar to remove burrs, other irregularities, and sharp corners from the bar. Manufacturing the dual interface separable insulated connector can include molding a semi-conductive rubber faraday cage over a conductive bus bar, inserting the faraday cage into a shell, and injecting insulating material between the faraday cage and shell.

Abstract: Concealed object detection using electromagnetic and acoustic multistatic imaging systems and methods. A method of simultaneously screening plural subjects for concealed objects includes transmitting a signal into a screening area where there is at least one subject to be screened having an associated object, receiving a reflected signal from the object when the object is located within the screening area, processing the reflected signal using multistatic Fourier space sampling and tomographic reconstruction to generate a three-dimensional image of the object and displaying the three-dimensional image. The transmitting and receiving are performed using a multi-directional array including at least three sensors. An object detection system includes a screening area, a multi-directional array including at least three sensors, a processor configured to execute multistatic Fourier space sampling and tomographic reconstruction and a display.

Abstract: Coffee machine, comprising at least one steam generator for producing steam and an apparatus for producing the coffee with associated dispensing device, a storage tank containing a ready prepared liquid chocolate product with a density suitable for being a conventional chocolate beverage, a heating device provided with an inlet and an outlet for the product to be heated and an inlet for introducing the steam, a line between said storage tank and the inlet of said heating device, a metering pump arranged along said line for conveying a predetermined amount of chocolate-based product from said storage tank to said heating device and for circulating it inside it, a line for the steam, connecting said steam generator to said inlet for the steam of the heating device, an intercept valve arranged along the said steam line as well as a beverage dispensing device connected to the outlet of the said heating device.

Abstract: An intelligent solution for monitoring, assigning, and accounting fueling operations. An automated dispatch fueling system comprises a fuel management server populated with airport profile and dispatcher configurations. Utilizing information stored in the database and received from external systems, the automated dispatch fueling system can automatically assign and monitor fueling operations.