Abstract: The invention provides a flow control system well suited for use in intravenous fluid delivery systems comprising a flow restrictor wafer having one or more flow limiting flow restrictor paths formed thereon. The system provides fixed flow rate control. The system also provides means for selectively orienting at least two flow restrictor paths relative to the main fluid passage to varying the flow rate.
Abstract: A process to determine the concentration of any substance in a colorimetric, turbidimetric or nephelometric reaction using a fluorometric detector to measure fluorescence intensity. In particular, a change in color can be monitored by observing the measurement of fluorescence intensity of a fluorophore in an inert matrix. The absorption spectrum of the chromophore may overlap the excitation and/or emission spectrum of the fluorophore, thereby allowing the change in fluorescence to be related to the intensity of color in the reaction and thus related to the quantity of the substance of interest.
Type:
Grant
Filed:
November 5, 1990
Date of Patent:
December 22, 1992
Assignee:
Baxter Diagnostics Inc.
Inventors:
Roger J. Morris, Shoshana Bascomb, Carolyn S. Olson
Abstract: Method and apparatus are provided for machine separation of blood into blood components, wherein a preselected fluid such as anticoagulant is added to at least two different locations through the fluid flow path of the set, in order to promote the different functional characteristics in different blood components. The method results in reduced incidence of citrate reaction in the blood donor and increased platelet yield in platelet rich plasma collected during the procedure.
Type:
Grant
Filed:
June 14, 1990
Date of Patent:
December 15, 1992
Assignee:
Baxter International Inc.
Inventors:
Yean Yow Hwang, Brian Ritchey, Donald W. Schoendorfer
Abstract: A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. A blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula the locking member latches to the injection site forming a mechanically coupled unit.
Abstract: A pharmaceutical composition is provided comprising an unbuffered iso-osmotic aqueous formulation containing an effective amount of ranitidine for the treatment of conditions mediated through histamine H.sub.2 receptors. The formulation has a pH of greater than or equal to 5.0 and less than 6.5 and preferably includes an osmotic adjusting agent chosen from the group consisting of dextrose and sodium chloride.
Abstract: A pre-slit injection site includes a housing with a flow path therethrough. A first end of the housing carries a pre-slit septum. A blunt cannula, usable with the injection site, carries a locking member. When the pre-slit injection site slidably receives the blunt cannula the locking member latches to the injection site forming a mechanically coupled unit.
Abstract: The present invention provides a sheath for at least removably covering the blunt end of the cannula. The sheath allows the cannula to be presterilized and utilized without subsequent sterilization. The sheath comprises a body member defining an interior for receiving at least a portion of the blunt cannula, the body member including a first end and a second end, the second end having an opening for receiving at least a portion of the cannula. The first end including a wall member so constructed and arranged as to rip upon the exertion of a sufficient perpendicular force by an end of the blunt cannula. The body also includes side walls extending between the first and second end, the side walls are so constructed and arranged so as to slide back along the cannula toward the second end upon the tearing of the first end by the cannula and the application of a sufficient force upon the side walls.
Abstract: A cover 10 for a waste disposal container 12 is disclosed. The cover 10 includes a body configured to cover an opening 68 defined by a waste disposal container 12. The body 14 has an orifice 20 therethrough for permitting access to a waste disposal container 12 upon which the cover 10 is placed. A lid 26 is threadably removably attachable to the body 14 for blocking the orifice 20 and preventing access to a waste disposal container 12 upon which the cover 10 is placed. A plurality of posts 36,38,40,42 are provided on the top 16 of the planar body 14 for releasably holding the lid 26 in a fixed storage position on the body when the lid 26 is not in its operative position of the body.
Abstract: A dual-lumen oocyte collection device is described. The device is unique in that it includes parallel cannulas which extend axially outward from a proximal end of a hub. The device is also unique in that it further includes a finger depression on the hub. This depression located on the hub directly corresponds to an elongated beveled point of a cannula that extends from a distal end of the hub. The unique parallel cannulas and the finger depression allow medical personnel to evenly rotate and accurately orientate the beveled tip of the device to puncture a follicle on an ovary with minimal trauma prior to collecting an oocyte.
Abstract: A valveless positive displacement pump including a closed end cylinder having two fluid inlet and outlet ports adjacent the closed end. A piston reciprocably and rotatably driven in the cylinder and including a reduced area portion on one free end which communicates cyclically with the inlet and outlet ports to pump fluid through the positive displacement pump. The piston reduced area is a reduced radius portion to minimize air bubble buildup and to minimize fluid volume at the end of the piston stroke. The piston also has a gland area formed in the piston which cyclically communicates with a pair of ports to clean the piston and cylinder and prevent the buildup of solids. The piston and cylinder can be formed from a hard ceramic material for accuracy and wear resistance. The cylinder is closed by a resilient end cap to relieve pressures caused by piston movement when the inlet and outlet ports are closed.
Type:
Grant
Filed:
April 15, 1991
Date of Patent:
October 27, 1992
Assignee:
Baxter International Inc.
Inventors:
James D. Aid, Edward R. Lindsay, Robert C. Kusmierczyk
Abstract: A system is described for the collection and re-infusion of fluids from a patient. The system includes a non-disposable rigid cannister and a disposable flexible liner that is placed in the cannister. Fluids are collected from a patient in the cannister liner. The liner is then removed from the cannister and the contents are re-infused back into a patient. The system is unique in that it provides a stand along vacuum means for continuously providing a relatively high vacuum to the cannister and a relatively low vacuum inside the liner to cause the liner to expand against the walls of the cannister. The stand alone vacuum means also provides a consistent relatively low vacuum to a patient's cavity for collecting fluids from the patient without damaging the patient's internal organs.
Abstract: The present invention provides housing containing a cylindrical, prestress member around which an elongated elastomeric bladder is wrapped. This interior of the bladder defines a fluid chamber. A filling port and an exit port are provided in fluid communication with the fluid chamber to provide for filling and dispensing of the liquid. The elongated bladder is wrapped around the cylindrical, prestress member so that the bladder is prestressed in the axial direction when disposed thereon.
Type:
Grant
Filed:
July 8, 1991
Date of Patent:
August 4, 1992
Assignee:
Baxter International Inc.
Inventors:
Steve Hessel, Gil Jemmott, William C. Brown
Abstract: Method and apparatus for machine separation of blood and blood components that utilizes improved administeration of anticoagulant to the red cell suspension output. Anticoagulant is added to incoming whole blood in an amount sufficient to prevent clotting of the whole blood in the flow path upstream of the blood component separator, but in an amount insufficient to prevent clotting of the red cell suspension created by the separator. Anticoagulant is added to the red cell suspension downstream of the separator in order to prevent clotting. By adding an additional aliquot of anticoagulant to the red cell suspension, the amount of anticoagulant added to whole blood before separation can be reduced or eliminated, resulting in an increase in platelet yield during the blood component separation step.
Abstract: A dancer assembly for feeding a web of film having ports extending therefrom to a former for folding the web of film. The apparatus includes a dancer having a roller located between two tracks that allow the roller to move vertically along the tracks. The web of film being fed around the roller and vertically upwards toward the former. A quarter turn member for changing the flow path of the film from a substantially horizontal flow path to a substantially vertical flow path. And a member for moving horizontally, as a unit, the dancer and quarter turn member while maintaining a fixed spacial orientation of the dancer and the quarter turn. A method of feeding a web of film to a former is also provided.
Abstract: Systems and methods of collecting blood cells use a first container connected to initially collect blood. A filtration system is provided that uses two flow paths, the first being a dual purpose path that is initially used to convey plasma and platelets to a pair of transfer/storage containers. A second flow path leads to a temporary transfer container through a filtration device. The dual purpose fluid path is next used to convey blood cells, now substantially free of undesired matter, from the temporary storage container to a storage container. The filtration system is then detached from the blood collection system.
Abstract: A peristaltic pump comprising a housing (19), including a base (21), a resilient tube (27) and a peristaltic pumping fingers (31) carried by the supporting structure. The tube (27) is positionable on the base (21) in a proper position and an improper position. In the proper position, the peristaltic pumping fingers (31) can properly progressively squeeze the tube to pump a fluid through the tube and in an improper position. A door (23) is mounted on the housing (19) for movement between an open position and a closed position. A latch (25) includes a pivotable latch member (51) on the door (23) and a fixed latch member (55) on the housing (19). The pivotable latch member (51) is movable between a latching position in which the door (23) is locked in the closed position and a releasing position in which the door (23) is not locked in the closed position. If the tube (27) is in the improper position, the pivotable latch member (51) is prevented from being placed in the latching position.
Abstract: A class of fluorescent rare earth chelates and the ligands upon which they are based whose molecular structure incorporates a plurality of substituted arylpyridine diacid units attached to a central template structure is disclosed. These ligands function as efficient energy transfer groups in fluorescent tagging reagents and tracers.