Patents Represented by Attorney Paul J. Cook
  • Patent number: 5554414
    Abstract: A composite porous article is formed from a porous polymeric substrate having its entire surface modified with a cross-linked polymer which results in a hydrophobic and oleophobic surface. The composite retains substantially all of the other original properties of the substrate. The cross-linked polymer is formed in situ on the polymeric substrate from a reactant system comprising an ethylenically unsaturated monomer having at least one fluoroalkyl group, a cross-linker, and, if needed, a polymerization initiator, dissolved in a polar solvent system. The porous substrate saturated with the reactant system is exposed to a suitable energy source to effect polymerization and cross-linking of the monomer.
    Type: Grant
    Filed: April 12, 1995
    Date of Patent: September 10, 1996
    Assignee: Millipore Investment Holdings Limited
    Inventors: Wilson Moya, Philip M. Goddard
  • Patent number: 5531899
    Abstract: A composite ultrahigh molecular weight polyethylene microporous membrane is provided having cation exchange capacity. The membrane is useful for removing metal ions from acidic aqueous solutions.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: July 2, 1996
    Assignee: Millipore Investment Holdings Limited
    Inventors: Larry Y. Yen, Ven Anantharaman, Bipin Parekh
  • Patent number: 5527672
    Abstract: A portion of a hydrophobic membrane, having an unknown concentration of a first molecule in a sample bound to its surface, is incubated with a second molecule that selectively binds to the first molecule so as to allow determination of its concentration. The membrane is first coated with the first molecule and then dried to render the uncoated portion nonwettable with water. The labeled second molecule selectively binds to the first molecule in the absence of a blocking agent on the membrane.
    Type: Grant
    Filed: October 24, 1994
    Date of Patent: June 18, 1996
    Assignee: Millipore Investment Holdings Limited
    Inventors: Michael A. Mansfield, Larry Sivik
  • Patent number: 5522991
    Abstract: A cellulosic ultrafiltration membrane is provided having a microporous base resistant substrate and an ultrafiltration layer form of a cellulose ester or cellulose.
    Type: Grant
    Filed: July 20, 1994
    Date of Patent: June 4, 1996
    Assignee: Millipore Investment Holdings Limited
    Inventors: Ronald Tuccelli, Paul V. McGrath
  • Patent number: 5520921
    Abstract: A periodontal packing device is provided comprising a plate having two through holes for a thread. A second set of holes can be provided for packing material. The thread is passed through the two through holes to form a thread loop adjacent one surface of the plate and two ends which are tied together adjacent a second surface of the plate.
    Type: Grant
    Filed: February 1, 1994
    Date of Patent: May 28, 1996
    Assignee: Wellesley Research Associates, Inc.
    Inventor: Paul R. Chalifoux
  • Patent number: 5498335
    Abstract: A product having a porous polymeric structure is formed from a non-porous polymeric sheet by sequential contact of the non-porous sheet with a solvent for the sheet and then a non-solvent for the sheet. The porous product can be porous through all or a portion of its thickness.
    Type: Grant
    Filed: July 21, 1993
    Date of Patent: March 12, 1996
    Assignee: Millipore Corporation
    Inventor: Wilson Moya
  • Patent number: 5478462
    Abstract: Polyimide-metal laminates are formed by etching the surfaces of a polyimide web with a glycol-containing etchant followed by electroless nickel or cobalt deposition and then by copper per deposition. The glycol containing etchant can be utilized to form through holes through the web.
    Type: Grant
    Filed: June 16, 1994
    Date of Patent: December 26, 1995
    Assignee: Polyonics Corporation, Inc.
    Inventor: Daniel P. Walsh
  • Patent number: 5477716
    Abstract: A device is provided comprising a piezoelectric material and at least one non-crystalline non-crystalline metal oxide, crystalline-non-zeolite metal oxide and mixtures thereof coating chemically reactive with trace quantities of water in chemically reactive and inert gases. The piezoelectric material is bonded to a conductor for delivering an alternating electric current and to a conductor for transmitting resonant vibration frequency of the crystal. The reactive metal oxide coating has an effective thickness which provides a serviceable life for the coating while not being so thick as to prevent vibration of the piezoelectric material.
    Type: Grant
    Filed: July 27, 1994
    Date of Patent: December 26, 1995
    Assignee: Millipore Corporation
    Inventor: James T. Snow
  • Patent number: 5477155
    Abstract: A new method and apparatus is described for conducting an integrity test on porous membranes and membrane filters and for conducting a pore-size characterization of membrane. The method and apparatus apply to membrane integrity tests and pore-size characterizations which are based on the dependence on the pore size of the pressure required to intrude a non-wetting, electrically conductive liquid into and through the pores. Electrical-measurement methods are described for identifying the pressure at which intrusion occurs.
    Type: Grant
    Filed: August 11, 1993
    Date of Patent: December 19, 1995
    Assignee: Millipore Corporation
    Inventors: Stephen Proulx, John L. Burns, Jr., Scott Emory, Richard W. Gray, Frank M. Lentine
  • Patent number: 5457986
    Abstract: A process is provided for rapidly and non-destructively evaluating the solute retention characteristics of porous membranes using a novel liquid-porosimetric technique. A ratio of two membrane permeabilities is measured at preselected operating conditions using a pair of mutually immiscible fluids, one of which is employed as a membrane wetting agent and the other used as an intrusion fluid. At the first operating condition, a particular transmembrane pressure is chosen so as to intrude nearly all of the pores present in the membrane sample. At the second operating condition, a particular membrane permeability is chosen so as to achieve a specified permeability ratio. The resulting transmembrane pressure corresponding to this particular membrane permeability is compared to a previously established standard curve which permits identifying the solute retention characteristics of the porous membrane.
    Type: Grant
    Filed: January 28, 1994
    Date of Patent: October 17, 1995
    Assignee: Millipore Corporation
    Inventors: Anthony J. DiLeo, Michael W. Phillips
  • Patent number: 5458488
    Abstract: A dental post-dental implant system is provided wherein the post is provided with a circumferential collar that mates with an upper portion of a circumferential wall of the implant. The circumferential collar resists expansion of the implant after being positioned in a patient.
    Type: Grant
    Filed: February 10, 1994
    Date of Patent: October 17, 1995
    Assignee: Wellesley Research Associates, Inc.
    Inventor: Paul R. Chalifoux
  • Patent number: 5448874
    Abstract: The packaging is in the form of a tape comprising first and second films (4,6) between which are sandwiched objects (7) each placed in an envelope formed by a seal (8) between the films. The first method and the device (20) enable the envelopes to be opened and the objects (27) to be taken therefrom easily. The microbiological analysis method uses a tape with alternating filter membranes for the liquid to be analyzed and absorbent pads for a nutrient medium.
    Type: Grant
    Filed: August 17, 1993
    Date of Patent: September 12, 1995
    Assignee: Millipore S.A.
    Inventor: Jean Lemonnier
  • Patent number: 5443723
    Abstract: A membrane support apparatus is provided which includes a top section, a mating base section and a membrane support surface within the mated sections. The apparatus includes a first peripheral seal formed by extension on one of the sections which mates with a groove on the other of the sections, a second seal formed by a smooth surface on either the groove or the extension which mates with a bead on the other of the groove or extension to form a second peripheral seal. The top section and the base section optionally can form a third peripheral seal about the periphery of a membrane on the membrane support surface.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: August 22, 1995
    Assignee: Millipore Corporation
    Inventors: Ralph Stankowski, John Milcetich
  • Patent number: 5444097
    Abstract: Porous polymeric structures are provided along with a method to make such structures comprising heat-induced phase separation of a polymeric solution exhibiting a lower critical solution temperature.
    Type: Grant
    Filed: July 7, 1992
    Date of Patent: August 22, 1995
    Assignee: Millipore Corporation
    Inventor: Gabriel Tkacik
  • Patent number: 5439587
    Abstract: A self-priming filter holder for filtration of intravenous liquids is provided and is formed of one or two housing portions sealed to a core portion. The core portion has one or two ribbed surfaces forming a plurality of flow paths sealed at one end and open at a second end and at least one channel preferably larger than the flow paths. The channel(s) is in fluid communication with the flow paths and an outlet. An inlet is provided to the interior of the housing portion(s) which are sealed from the ribbed surfaces by hydrophilic membranes. The housing portion(s) can be provided with gas vents sealed with hydrophobic membranes. Fluids pass through the flow paths in one direction and through the channel(s) in an opposite direction to remove gas from the flow paths and channels prior to use.
    Type: Grant
    Filed: July 27, 1993
    Date of Patent: August 8, 1995
    Assignee: Millipore Corporation
    Inventors: Ralph J. Stankowski, Michael C. Heath, Douglas A. Boucher
  • Patent number: 5437551
    Abstract: A dental implant is provided for insertion into the jawbone of a patient for the purpose of building a dental prosthesis thereon. The implant includes a central hole having a wall with first extension for accommodating a dental post having a second extension that frictionally interlock with the first extension. A core can be provided which includes a second central hole having a wall with a third extension for accommodating a dental post having a fourth extension that frictionally interlocks with the third extension.
    Type: Grant
    Filed: June 14, 1993
    Date of Patent: August 1, 1995
    Assignee: Wellesley Research Associates, Inc.
    Inventor: Paul R. Chalifoux
  • Patent number: 5436446
    Abstract: A system for forming a time modulated electrospray from a sample solution is provided. Further systems for analyzing this time modulated electrospray also are provided. An element connected to a time modulated voltage source is positioned substantially opposite an electrospray apparatus and an analytical apparatus so that the initial direction of travel of the electrospray is reversed and the electrospray is diverted into the analytical apparatus. A second time modulated voltage can be provided which causes the periodic deflection of an ion beam, resulting from a time modulated electrospray, into a mass analyzer in a vacuum system. The modulation of this second voltage source is coordinated with the time modulation of the first voltage source which causes the formation of an electrospray in such a manner that efficiency of sample introduction into the mass analyzer is improved.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: July 25, 1995
    Assignee: Waters Investments Limited
    Inventors: Joseph A. Jarrell, Michael J. Tomany
  • Patent number: 5413925
    Abstract: The present invention describes a cartridge of hollow fibers intended principally for the refermentation in the bottle of sugar-containing wine according to the traditional so-called "champagne" method. The cartridge has a perforated tubular body in which are arranged microporous hollow fibers preferably hydrophilic and a few hydrophobic and which are folded in a U shape and which are filled with yeasts. The cartridge is of a size to be inserted in the neck of a bottle and allows refermentation to occur by ensuring the maintenance of an optimum exchange surface between the wine and the yeasts.
    Type: Grant
    Filed: January 19, 1993
    Date of Patent: May 9, 1995
    Assignee: Millipore S. A.
    Inventor: Jean Lemonnier
  • Patent number: 5406743
    Abstract: An insect trap is provided comprising a container having a bottom to support a liquid bait add a bait tray for a solid bait. Insect entry ramps extend through the container walls and are spaced apart a short distance from the bait tray.
    Type: Grant
    Filed: June 2, 1992
    Date of Patent: April 18, 1995
    Assignee: Green Leaf Products, Inc.
    Inventors: Bernice J. McSherry, Michael J. Grady
  • Patent number: 5389262
    Abstract: Heavy metal ions react with ferrous dithionite in acidic aqueous solution. They are reduced to metallic particles that are suitable for recycling and reuse when recovered from the acidic water. Chelating agents that are present are deactivated by bonding to the ferrous ions. Ferrous dithionite, (FeS.sub.2 O.sub.4) is either generated in-situ or ferrous ions and dithionite ions can be provided by other methods. An alkali metal hydroxide is utilized to precipitate remaining heavy metal ions including ferrous and ferric ions.
    Type: Grant
    Filed: March 28, 1994
    Date of Patent: February 14, 1995
    Assignee: Romar Technologies, Inc.
    Inventor: Robert G. Guess