Patents Represented by Attorney Robert S. Honor

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  • Pharmaceutical compositions comprising clozapine and a radical scavenger
    Patent number: 5563134
    Abstract: The invention concerns pharmaceutical compositions comprising clozapine and a radical scavenger.
    Type: Grant
    Filed: July 2, 1993
    Date of Patent: October 8, 1996
    Assignee: Sandoz Ltd.
    Inventors: Volker Fischer, Ronald P. Mason
  • Acidic monoazo dyestuffs
    Patent number: 5563249
    Abstract: Acidic monoazo dyestuffs of formula I ##STR1## and their salts wherein the symbols R.sub.1 to R.sub.6, which possess the significances given in claim 1. These dyestuffs are suitable for dyeing or printing textile material consisting of natural or synthetic polyamides.
    Type: Grant
    Filed: June 21, 1995
    Date of Patent: October 8, 1996
    Assignee: Sandoz Ltd.
    Inventor: Jacky Dore
  • Phthalocyanine solvent dyes
    Patent number: 5563260
    Abstract: The compounds of general formula I ##STR1## wherein R represents chlorine or hydroxylPc represents a phthalocyanine radicalR.sub.1 may be alkyl and R.sub.2 may be alkyl ammoniumare excellently suitable for dyeing of plastic materials, paper and inks for ball point pens.
    Type: Grant
    Filed: February 9, 1995
    Date of Patent: October 8, 1996
    Assignee: Sandoz Ltd.
    Inventors: Bansi L. Kaul, Dominique Pflieger
  • Pseudopeptide isosteres of gly-asp and their use as antithrombic agents
    Patent number: 5561112
    Abstract: Pseudopeptides of formula I in free or salt form ##STR1## wherein A, B, R.sub.1, X, Y and m are defined as in claim 1, and their use in the prophylactic and acute treatment of thrombosis.
    Type: Grant
    Filed: March 1, 1994
    Date of Patent: October 1, 1996
    Assignee: Sandoz Ltd.
    Inventors: Georg Kottirsch, Rainer Metternich
  • Use of certain imidazol carbazols in treating stress-related manic-depressive disorders
    Patent number: 5561149
    Abstract: Use of a mono or bicyclic carbocyclic, or heterocyclic carboxylic, acid ester or amide or an imidazolyl carbazol in the manufaccure of a medicament suitable for the treatment of stress-related psychiatric disorders, for increasing vigilance, for the treatment of rhinitis or serotonin-induced disorders and/or coadministration with another active agent to increase the bioavailability thereof, or for nasal administration.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: October 1, 1996
    Assignee: Sandoz Ltd.
    Inventors: Moise Azria, Karl-Heinz Buchheit, Keith A. Dixon, G unther Engel, Rudolf K. A. Giger
  • Use of 4H-3,1-benzoxazin-4-one compounds to improve the light fastness of textile materials
    Patent number: 5560852
    Abstract: A method of improving the light fastness of textile materials using an aqueous dispersion of a compound of formula I, ##STR1## having a first (A) and a second (B) benzoxazine-4-one ring joined by a phenylene bridging member; a variable bond between the first benzoxazine-4-one ring (A) and the phenylene bridging member, said variable bond being meta- or para- to the bond between the second benzoxazine-4-one ring (B) and the bridging member; wherein each R.sub.1 is independently hydrogen, halogen, nitro, C.sub.1-2 alkyl, C.sub.1-4 alkoxy, carboxy, sulfonic acid, C.sub.1-3 alkylcarbonyl, benzoyl or C.sub.1-4 alkoxycarbonyl and; R.sub.2 is hydrogen, chlorine, bromine, methyl, C.sub.1-2 alkoxy, phenyl, hydroxy, nitro, carboxy or sulfonic acid.
    Type: Grant
    Filed: March 22, 1995
    Date of Patent: October 1, 1996
    Assignee: Sandoz Ltd.
    Inventor: Jean-Luc Mura
  • Cementitious compositions
    Patent number: 5556458
    Abstract: A cementitious composition comprising(a) a cementitious material;(b) a fly ash which has a calcium oxide content of from 15-45% by weight;(c) a hydroxycarboxylic acid; and(d) a water-soluble source of alkali metal ions.The compositions are useful as concretes, grouts and mortars.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: September 17, 1996
    Assignee: Sandoz Ltd.
    Inventors: John W. Brook, David F. Factor, Frederick D. Kinney, Celeste L. McCallen, Andrea M. Young
  • Blister pack scanner device
    Patent number: 5555707
    Abstract: A blister pack scanning device for detection and removal of overfilled or defective pharmaceutical blister packs is comprised of a photoelectric LED transmitter and sensor with a scanning beam channel bar disposed therebetween. The blister pack web is passed below the bar through a space precisely equivalent to the thickness of a properly filled blister. Overfilled or improperly molded blisters will contact a beveled edge of the bar as the web passes thereunder and the lateral movement forces the bar and its two end plates which are in juxtaposition to the transmitter and receiver respectively, to move upward, thereby interfering with the beams transmission. The interference created thereby shuts off the blister production machine and sounds an alarm for removal of the defective package.
    Type: Grant
    Filed: February 18, 1994
    Date of Patent: September 17, 1996
    Inventor: Hans O. Schwenger
  • Dyeing process and auxiliary
    Patent number: 5554199
    Abstract: Dyeing of cellulosic substrates with reactive dyes in the presence of at least 20 g/l of sodium chloride, employing auxiliaries (E) of levelling activity, which are methylene-bridge-containing and sulpho-group-containing aromatic compounds, obtainable by condensation of defined sulphonation products with formaldehyde resp. formaldehyde-yielding compounds and optionally salt formation; (E)-contaning compositions that further contain at least one hydrotrope (H) and/or at least one sequestering agent (Q); and novel condensation products.
    Type: Grant
    Filed: November 17, 1994
    Date of Patent: September 10, 1996
    Assignee: Sandoz Ltd.
    Inventor: Hans-Peter Baumann
  • Feeding tube retaining strap
    Patent number: 5554140
    Abstract: Retaining device on a single-port feeding tube connector for patient feeding set to prevent unintentional disconnect of the feeding solution supply tube from the feeding tube.
    Type: Grant
    Filed: March 11, 1994
    Date of Patent: September 10, 1996
    Assignee: Sandoz Nutrition Ltd.
    Inventors: Lester D. Michels, Douglas J. Duchon, Norman C. Reid
  • White-rot fungus and uses thereof
    Patent number: 5554535
    Abstract: The white rot fungus Scytinostroma galactinum strain F361 and mutants thereof are particularly effective in selectively grading the lignin component of lignin-containing materials, particularly processed wood pulps including chemical pulps, and also particularly effective in degrading lignin degradation products such as chlorinated degraded lignin by-products as found, for example, in E-1 effluents, and also in degrading chlorine-containing aromatic compounds generally as found in aqueous waste streams containing the same.
    Type: Grant
    Filed: October 28, 1994
    Date of Patent: September 10, 1996
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Robert A. Blanchette, Theresa S. Brush, Roberta L. Farrell, Keith A. Krisa, Chittra Mishra
  • Azo dyes containing a 2-(arylsulphonylamino)pyrimidine radical
    Patent number: 5554736
    Abstract: The invention provides a process for the production of azodyes and their derivatives by diazotization and coupling reactions and optionally further modification reactions, wherein a compound of formula ##STR1## in which E signifies an aromatic bivalent radical,X.sub.1 signifies hydroxy or a primary amino group,Y.sub.1 signifies hydroxy or a primary amino groupand in which the aminogroup linked to the --SO.sub.2 -bound phenyl radical may optionally be acylated,or a mixture of compounds of formula (I), is employed as a coupling component or/and--in the non-acylated form--as a diazo component,the invention in particular relates also to the novel dyes and their use and to the novel intermediates.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: September 10, 1996
    Inventors: Jordi B. Barra, Jose R. Sorolla
  • Fibre-reactive disazo dyestuffs
    Patent number: 5554732
    Abstract: Fibre-reactive disazo compounds of the formula ##STR1## which compounds are in free acid or salt form, and mixtures thereof, are useful for dyeing or printing hydroxy group- or nitrogen-containing organic substrates, for example leather and fibre material comprising natural or synthetic polyamides or natural or regenerated cellulose; the most preferred substrate is a textile material comprising cotton.
    Type: Grant
    Filed: May 2, 1995
    Date of Patent: September 10, 1996
    Assignee: Sandoz Ltd
    Inventors: Rainer Nusser, Roland Wald
  • Process for the production of resist prints
    Patent number: 5554195
    Abstract: This invention relates to a process for the production of resist prints on two-dimensional textile materials, which is characterized by the steps of impregnating with a water-repellent those parts of one side of a textile piece which are to be given a resist effect, drying said textile piece and dyeing the textile piece by applying an aqueous liquor to the reverse side.
    Type: Grant
    Filed: June 1, 1995
    Date of Patent: September 10, 1996
    Assignee: Sandoz Ltd.
    Inventor: Georg Robert
  • Pinitol and derivatives thereof for the treatment of metabolic disorders
    Patent number: 5550166
    Abstract: Pinitol and derivatives and metabolites thereof are useful in nutritional and medicinal compositions for treating conditions associated with insulin resistance, such as diabetes mellitus and its chronic complications; obesity; hyperlipidemias and dyslipidemias atherosclerosis; hypertension; cardiovascular disease; AIDS; cancer; wasting/cachexia; sepsis; trauma associated with burns, malnutrition, and stress; aging; lupus and other autoimmune diseases; endocrine disease; hyperuricemia, polycystic ovary syndrome and complications arising from athletic activity or inactivity.
    Type: Grant
    Filed: March 17, 1995
    Date of Patent: August 27, 1996
    Inventors: Richard E. Ostlund, William R. Sherman
  • Azo compounds having unsubstituted or substituted 2-phenoxycarbonylethyl groups
    Patent number: 5550218
    Abstract: Compounds of the formula ##STR1## wherein A is C.sub.1-6 alkylene, D is a diazo component radical of the triazolyl, pyrazolyl, cyano(C.sub.1-4 alkyl)-imidazolyl, 4-chlorothiazolyl, 4-chlorotheinyl-2, 3-phenyl-1,2,4-thiadiazolyl-5, isothiazolyl-5, benzoisothiazolyl-3 or 1,3,4-thiadiazolyl-5 series or the phenyl series wherein the phenyl group is free of sulfonyl groups and may be substituted, by a maximum of 3 substituents 5-nitrothiazolyl-2, ##STR2## R.sub.1a is phenyl or phenyl substituted by 1 to 4 substituents each of which is independently halo, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, trifluoromethyl, hydroxy, nitro, formyl, cyano, --SCN, (C.sub.1-4 alkyl)carbonyl, (C.sub.1-4 alkyl)carbonylamino, (C.sub.1-4 alkoxy)carbonyl, (C.sub.1-4 alkyl)carbonyloxy, carbamoyl, (C.sub.1-2 alkoxy)(C.sub.2-3 alkoxy)carbonyl or phenyl, andR.sub.2 -R.sub.4 and R.sub.10 -R.sub.
    Type: Grant
    Filed: October 6, 1994
    Date of Patent: August 27, 1996
    Assignee: Sandoz Ltd.
    Inventor: Ruedi Altermatt
  • Process for treatment of waste stream using Scytinostroma galactinum fungus ATCC 20966
    Patent number: 5545544
    Abstract: The white rot fungus Scytinostroma galactinum strain F361 and mutants thereof are particularly effective in selectively grading the lignin component of lignin-containing materials, particularly processed wood pulps including chemical pulps, and also particularly effective in degrading lignin degradation products such as chlorinated degraded lignin by-products as found, for example, in E-1 effluents, and also in degrading chlorine-containing aromatic compounds generally as found in aqueous waste streams containing the same.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: August 13, 1996
    Assignees: Sandoz Ltd., The Regents of the Univ. of Minnesota
    Inventors: Robert A. Blanchette, Theresa S. Brush, Roberta L. Farrell, Keith A. Krisa, Chittra Mishra
  • Cationically bridged tetrakisazo dyestuffs with variable couplers, their production and use
    Patent number: 5545724
    Abstract: The invention relates to cationically bridged tetrakisazo compounds, corresponding to formula I, ##STR1## wherein the individual symbols are defined as in claim 1, as well as residues and liquid preparations thereof. The compounds and their preparations are used for dyeing and printing hydroxy-group-containing or nitrogen-containing organic substrates by a known method. Preferred substrates are textile materials which consist of or contain cellulose, especially cotton, or also bast fibres, leather and preferably paper or paper pulp products, especially wood-containing paper.
    Type: Grant
    Filed: October 10, 1995
    Date of Patent: August 13, 1996
    Assignee: Sandoz Ltd.
    Inventor: Helmut A. Moser
  • Pleuromutilin derivatives
    Patent number: 5545654
    Abstract: A compound of formula (I), in which each of R.sub.1 and R.sub.2 is independently hydrogen, alkyi or, together with the carbon atom to which it is bonded, a cycloalkyl; and each of R.sub.3 and R.sub.4 is independently hydrogen, alkyl or substituted alkyl. The compounds are useful intermediates and prodrugs.
    Type: Grant
    Filed: January 3, 1994
    Date of Patent: August 13, 1996
    Assignee: Biochemie Gesellschaft m.b.H.
    Inventor: Ingolf Macher
  • .beta.-crystal form of 4,4'-Diamino-3,3'-Dibromo-1,1'-Dianthraquinonyl
    Patent number: 5542975
    Abstract: The new .beta.-modification of the pigment 4,4'-diamino-3,3'-dibromo-1,1'-dianthraquinonyl, having characteristic lines in the X-ray diagram (Guinier/De Wolff, Cu K.alpha..sub.1 -radiation) according to the FIG. 1 has significant dyeing advantages over the known .alpha.-modification.
    Type: Grant
    Filed: June 21, 1995
    Date of Patent: August 6, 1996
    Assignee: Clariant Finance (BVI) Limited
    Inventor: Peter Bitterli