Patents Represented by Attorney Salvatore C. Mitri
  • Patent number: 4396616
    Abstract: Substituted enantholactam dipeptides and derivatives thereof are disclosed which are useful as converting enzyme inhibitors and as antihypertensives.
    Type: Grant
    Filed: September 4, 1981
    Date of Patent: August 2, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Elbert E. Harris, David Taub, Eugene D. Thorsett
  • Patent number: 4393242
    Abstract: Methylvanillyl ketone is prepared from a "through process" involving oxidation of isoeugenol followed by subsequent acidic hydrolysis.
    Type: Grant
    Filed: July 6, 1981
    Date of Patent: July 12, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Meyer Sletzinger
  • Patent number: 4393212
    Abstract: Novel substituted (3-loweralkylamino-2-R.sub.1 O-propoxy)pyridines, their pharmaceutically acceptable salts, certain intermediates and their preparation are disclosed. These pyridines have pharmaceutically useful properties such as .beta.-adrenergic blocking activity.
    Type: Grant
    Filed: May 13, 1981
    Date of Patent: July 12, 1983
    Assignee: Merck & Co., Inc.
    Inventors: John J. Baldwin, Gerald S. Ponticello
  • Patent number: 4389415
    Abstract: A pharmaceutical composition containing .alpha.-methyl-p-tyrosine and carbidopa and method of treating hypertension are described.
    Type: Grant
    Filed: July 20, 1981
    Date of Patent: June 21, 1983
    Assignee: Merck & Co., Inc.
    Inventor: Alexander Scriabine
  • Patent number: 4379146
    Abstract: There are disclosed substituted phosphonamides and related compounds which are useful as converting enzyme inhibitors and as antihypertensives.
    Type: Grant
    Filed: November 5, 1981
    Date of Patent: April 5, 1983
    Assignee: Merck & Co., Inc.
    Inventors: William J. Greenlee, Elbert E. Harris, Arthur A. Patchett, Eugene D. Thorsett
  • Patent number: 4374829
    Abstract: The invention relates to new carboxyalkyl dipeptide derivatives and related compounds which are useful as antihypertensives.
    Type: Grant
    Filed: February 17, 1981
    Date of Patent: February 22, 1983
    Assignee: Merck & Co., Inc.
    Inventors: Elbert E. Harris, Arthur A. Patchett, Edward W. Tristram, Matthew J. Wyvratt
  • Patent number: 4337360
    Abstract: Methylvanillyl ketone is prepared from a "through process" involving oxidation of isoeugenol followed by subsequent acidic hydrolysis.
    Type: Grant
    Filed: September 28, 1979
    Date of Patent: June 29, 1982
    Assignee: Merck & Co., Inc.
    Inventor: Meyer Sletzinger
  • Patent number: 4316896
    Abstract: The invention relates to new phosphoryl aminoacid derivatives and related compounds which are useful as antihypertensives.
    Type: Grant
    Filed: September 7, 1978
    Date of Patent: February 23, 1982
    Assignee: Merck & Co., Inc.
    Inventors: Eugene D. Thorsett, Arthur A. Patchett, Elbert E. Harris, Alan L. Maycock
  • Patent number: 4293703
    Abstract: Organic chemical compounds based upon the urea molecule are disclosed which have potent gastric secretion inhibitory properties. The urea is substituted with a heterocyclic ring which may be substituted with one or more loweralkyl groups. The urea is also substituted with loweralkyl and a lower-alkylamino loweralkyl group. The compounds have profound effects on the inhibition of gastric secretions in the gastro-intestinal tract, and compositions for such uses are also disclosed.
    Type: Grant
    Filed: July 7, 1980
    Date of Patent: October 6, 1981
    Assignee: Merck & Co., Inc.
    Inventor: William A. Bolhofer
  • Patent number: 4273943
    Abstract: Methylvanillyl ketone is prepared from a "through process" involving oxidation of isoeugenol followed by subsequent acidic hydrolysis.
    Type: Grant
    Filed: September 28, 1979
    Date of Patent: June 16, 1981
    Assignee: Merck & Co., Inc.
    Inventors: George Gal, Seemon H. Pines
  • Patent number: 4254273
    Abstract: Improved process for preparing esters of .alpha.-methyl-3,4-dihydroxyphenylalanine having pharmaceutical activity via novel N-(tert-butoxycarbonyl) intermediates.
    Type: Grant
    Filed: August 6, 1979
    Date of Patent: March 3, 1981
    Assignee: Merck & Co., Inc.
    Inventors: Burwell F. Powell, Ralph F. Hirschmann
  • Patent number: 4243575
    Abstract: Filled thermoplastic resin compositions are provided wherein the filler component is compatible with and does not deleteriously affect the physical properties of the resin. The filler employed is a particulate, solid sphere which can be pre-treated with a surface active agent prior to being incorporated in the resin. The resin composition can also contain other ingredients such as impact modifiers, glass fillers, and the like.
    Type: Grant
    Filed: July 25, 1979
    Date of Patent: January 6, 1981
    Assignee: General Electric Company
    Inventors: Donald C. Myers, Phillip S. Wilson
  • Patent number: 4238596
    Abstract: A process is disclosed for producing copolyester-carbonates by direct polymerization of a dihydric phenol and an acid dichloride at a single pH profile level.
    Type: Grant
    Filed: April 26, 1979
    Date of Patent: December 9, 1980
    Assignee: General Electric Company
    Inventor: Clayton B. Quinn
  • Patent number: 4231920
    Abstract: A transparent to translucent flame-retardant polycarbonate composition comprising a mixture of an aromatic carbonate polymer and a flame-retardant additive which can be the metal salts of organic sulfonic acids and a coadditive which can be a solvent for said metal salts.
    Type: Grant
    Filed: January 25, 1979
    Date of Patent: November 4, 1980
    Assignee: General Electric Company
    Inventors: Victor Mark, Charles V. Hedges
  • Patent number: 4230611
    Abstract: A plasticized polycarbonate composition comprising in admixture a high molecular weight aromatic carbonate polymer and a minor amount of a silane plasticizer.
    Type: Grant
    Filed: December 28, 1977
    Date of Patent: October 28, 1980
    Assignee: General Electric Company
    Inventors: Victor Mark, Phillip S. Wilson
  • Patent number: 4226950
    Abstract: Novel thermoplastic molding compositions are disclosed which comprise(a) a bisphenol-A polycarbonate;(b) an alcohol terminated polyester of neopentyl glycol (2,2-dimethyl-1,3-propane-diol) and adipic acid; in admixture with(c) a minor amount of at least one component selected from the group comprising polyolefins, olefin based copolymers and olefin based terpolymers, such as, ethylene-propylene copolymers, ethylene-butadiene copolymers, propylene-butadiene copolymers, ethylene-propylene-butadiene terpolymers, ethylene-acrylic acid copolymers, propylene-acrylic acid copolymers, ethylene-ethyl acrylate copolymers, ethylene-vinyl acetate copolymers and ethylene-propylene-acrylic acid terpolymers; or(d) an amount of at least one component selected from the group comprising methyl methacrylate-butadiene-styrene copolymers, methyl methacrylate-acrylonitrile-butadiene-styrene copolymers and acrylonitrile-butadiene-styrene copolymers.
    Type: Grant
    Filed: July 6, 1978
    Date of Patent: October 7, 1980
    Assignee: General Electric Company
    Inventors: Fred F. Holub, Phillip S. Wilson
  • Patent number: 4224434
    Abstract: A continuous process for obtaining highly pure, high molecular weight aromatic polycarbonates from highly pure, halogenated diphenols.
    Type: Grant
    Filed: February 28, 1978
    Date of Patent: September 23, 1980
    Assignee: General Electric Company
    Inventors: Clayton B. Quinn, Charles A. Wilson, II
  • Patent number: 4224215
    Abstract: Filled polycarbonate compositions are disclosed having improved impact properties and which comprise an admixture of a high molecular weight aromatic polycarbonate, a filler, and an organopolysiloxane-polycarbonate block copolymer additive.
    Type: Grant
    Filed: April 20, 1979
    Date of Patent: September 23, 1980
    Assignee: General Electric Company
    Inventor: Gerald F. Macke
  • Patent number: 4223170
    Abstract: Resistance to high heat distortion is imparted to high molecular weight aromatic polycarbonate resins by controlling the degree to which particular diphenols are halogenated so that there are obtained either highly pure dihalogenated diphenols or predetermined statistical mixtures comprising predominantly mono- and dihalogenated diphenols together with some unreacted diphenol.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: September 16, 1980
    Assignee: General Electric Company
    Inventor: Victor Mark
  • Patent number: 4223171
    Abstract: Improved flame retardance and improved water vapor transmission are imparted to high molecular weight aromatic polycarbonate resins by selecting appropriate diphenols and controlling the degree to which these particular diphenols are halogenated.
    Type: Grant
    Filed: June 18, 1979
    Date of Patent: September 16, 1980
    Assignee: General Electric Company
    Inventors: Victor Mark, Charles V. Hedges