Abstract: 2-Chloro-6-nitrophenyl alkyl sulphides of the formula ##STR1## in which the substituents are as defined in the description, can be prepared by reacting 2,3-dichloro-nitrobenzenes of the formula ##STR2## with mercaptans of the formulaHS-R.sup.1 (III)in the presence of 1-1.2 equivalents of a base per mole of mercaptan and in the presence of a phase transfer catalyst, at a temperature of 0.degree.-100.degree. C., in an aqueous or aqueous-organic medium. The majority of the 2-chloro- 6-nitrophenyl alkyl sulphides obtainable in this way are novel.
Abstract: New active compound combinations of valinamide derivatives of the formula (I) ##STR1## in which R.sup.1 and R.sup.2 has the meaning given in the description,with known fungicidal active substances, and their use for combating phytopathogenic fungi are described.
Type:
Grant
Filed:
November 6, 1995
Date of Patent:
July 22, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Heinz-Wilhelm Dehne, Wilhelm Brandes, Karl-Heinz Kuck, Thomas Seitz
Abstract: Herbicidal 1-cyclopropyl tetrazolinones of the formula ##STR1## wherein X represents C.sub.1-3 alkyl, C.sub.2-4 alkenyl or halogen,n represents 0 to 5,R.sup.1 and R.sup.2 each independently represents C.sub.1-6 alkyl, C.sub.2-6 alkenyl, C.sub.2-6 alkynyl, C.sub.3-7 cycloalkyl which may optionally be substituted by C.sub.1-3 alkyl, epoxy-C.sub.3-5 alkan-1-yl, phenyl which may optionally be substituted, or aralkyl which may optionally be substituted, orR.sup.1 and R.sup.2 together with the N-atom to which they are attached, represent a cyclic ring which may be substituted, and some novel intermediates therefor.
Abstract: Storage and selective information transmission system of personal data comprising at least one optical memory card on which a defined memory field for storing a multiplicity of key terms is provided, a multiplicity of codes each assigned to at least one key term, at least one read/write device for the optical memory card having a multiplicity of key recognition functions, one key recognition function in each case pointing to one of a multiplicity of formatting functions contained in the read/write device and activating said formatting functions in interaction with the respective assigned code, each formatting function pointing to a data storage field of the optical card and being qualified, on the basis of the associated format specifications, for reading the data stored there.
Type:
Grant
Filed:
February 9, 1995
Date of Patent:
July 22, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Wolfgang Ahrens, Georg Hartmann, Gunnar Weikert
Abstract: Optionally substituted ODOP is obtained by reaction of optionally substituted o-phenylphenol with PCl.sub.3 in the presence of Lewis acids at elevated temperature in a first stage, with according to the invention an excess of at least 0.05 mol of PCl.sub.3 per mol of o-phenylphenol being maintained during the entire reaction time, and, after removal of the PCl.sub.3, by hydrolysis in a second stage using 1-2 mol of H.sub.2 O per chlorine equivalent of the product of the first stage at 50.degree.-150.degree. C. and with removal of HCl and residual H.sub.2 O.
Type:
Grant
Filed:
September 12, 1995
Date of Patent:
July 22, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Hans-Josef Buysch, Volker Glock, Bernd Griehsel, Joachim Komoschinski
Abstract: Monomers of the formula (I) (for example, 3,3,4,4,5,5,6,6-octafluoromethylenecyclopentane) are described, as well as copolymers prepared from them and from one or more monomers copolymerizable with them. ##STR1## wherein n=3 to 5 The compounds are suitable for the production of a multiplicity of thermoplastically processable copolymers having various sets of properties which permit applications both as compact moulded parts and as coatings.
Type:
Grant
Filed:
May 31, 1995
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Ralf Kruger, Michael Negele, Norbert Lui, Albrecht Marhold
Abstract: The new fluoro-trifluoromethylbenzoic acid derivatives of the general formula (I) ##STR1## wherein the substituents R, R.sup.1, R.sup.2, R.sup.3, R.sup.4 and R.sup.5 have the meaning given in the description, are suitable as starting substances for the preparation of antibacterial agents and feed additives.
Abstract: Described herein are new benzimidazole derivatives of the formula ##STR1## in which R represents cyano or the group ##STR2## X.sup.1, X.sup.2, X.sup.3 and X.sup.4 are identical or different and represent halogen;Y represents alkyl, alkenyl or alkinyl, each of which is optionally substituted by halogen; or represents optionally substituted phenylalkyl or in each case optionally substituted cycloalkyl and cycloalkenyl; andZ represents hydrogen or halogen, a process for the preparation of these substances, and their use for controlling pests.
Type:
Grant
Filed:
October 29, 1996
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Lutz Assmann, Albrecht Marhold, Heinz-Wilhelm Dehne, Gerd Hanssler, Klaus Stenzel, Ulrike Wachendorff-Neumann
Abstract: Mononitrotoluenes can be prepared by intensively mixing together toluene, nitric acid, sulphuric acid and water, simultaneously or successively in their total amount, and, in the case of continuous preparation, redispersing the mixture at least twice, for which purpose a mixing energy of 1 to 40 watts per liter of the total reaction mixture, preferably 3 to 30 W/l, is employed per volume of the reactor, and, for the continuous procedure, the back mixing is substantially repressed. Adiabatic reaction conditions are maintained.
Type:
Grant
Filed:
July 12, 1996
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Bernd-Michael Konig, Helmut Judat, Heinz Ulrich Blank
Abstract: The present invention relates to a process for the preparation of 5-substituted 2-chloropyridines of the formula (I) ##STR1## by reaction of acetenamides of the formula (II) ##STR2## with Vilsmeier reagent, which is prepared by reaction of dialkylformamides of the formula (III) ##STR3## with a chlorinating agent, the excess of which is removed from the reaction mixture by distillation or by addition of dialkylformamide after completion of the reaction of the Vilsmeier reagent with the acetenamide of the formula (II), wherein in the formulae (I)-(III):R represents optionally substituted alkyl or aralkyl,R.sup.1 represents C.sub.1 -C.sub.4 -alkyl or aryl-C.sub.1 -C.sub.4 -alkyl,R.sup.2 and R.sup.3 represent straight-chain, branched or cyclic C.sub.4 -C.sub.8 -alkyl.
Type:
Grant
Filed:
January 11, 1996
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Klaus Jelich, Hans Lindel, Christoph Mannheims, Reinhard Lantzsch, Walter Merz
Abstract: Substituted chloroaromatics are obtained in a simple manner in virtually isomer-free form when substituted phenols of the formula (II) ##STR1## where R.sup.1 to R.sup.5 are each, independently of one another, hydrogen, C.sub.1 -C.sub.10 -alkyl, unsubstituted or substituted C.sub.6 -C.sub.10 -aryl or halogen, with at least one of these radicals being different from hydrogen,are reacted with dichlorotriphenylphosphorus.
Type:
Grant
Filed:
June 21, 1996
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Heinz Landscheidt, Witold Broda, Alexander Klausener
Abstract: Substituted 1,2,3,4-tetrahydrocarbazoles of the formula ##STR1## having the meaning for R.sup.1 to R.sup.8 indicated in the description, can be prepared by catalytically hydrogenating a substituted phenol of the formula ##STR2## reacting the hydrogenation solution with a phenylhydrazine of the formula ##STR3## to give the hydrazone and cyclizing the hydrazone under acidic conditions.
Type:
Grant
Filed:
February 29, 1996
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Heinz Landscheidt, Alexander Klausener, Eberhard Zirngiebl, Jorg-Dietrich Jentsch
Abstract: C.sub.1 -C.sub.4 -Alkyl nitrites can be prepared by reaction of C.sub.1 -C.sub.4 -alkanols with nitrogen oxides with the participation of oxygen in a reactor designed as a scrubber column, nitrogen oxides having a proportion of more than 50% of NO of the total amount of gram atoms of N of the nitrogen oxides, oxygen and optionally inert gas being fed into the lower part of the reactor. 5 to 60% of the total amount of C.sub.1 -C.sub.4 -alkanol used is likewise fed into the lower part of the reactor in vaporous or atomized form, while the remaining C.sub.1 -C.sub.4 -alkanol is delivered to the column head.
Type:
Grant
Filed:
December 11, 1995
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Heinz Landscheidt, Paul Wagner, Zoltan Kricsfalussy, Alexander Klausener
Abstract: A cast sliding surface bearing for guiding and supporting moving machine members consists of a light alloy matrix (4), which contains a cast-in shaped body (2), which constitutes portions of the sliding surface (6) and is made of a hard material and has open cavities, which contain infiltrated matrix material. In order to achieve improved tibological properties the open cavities of the shaped body are filled with matrix material, each of the hard portions of the shaped body which lie in the sliding surface has a size, measured in an axis, of .ltoreq.0.1 mm, and the distance between the hard portions of the shaped body, measured in an axis, is .ltoreq.2 mm.
Abstract: Process for the preparation of antibacterial compounds of the formula ##STR1## comprises condensing an oxo compound of the formula ##STR2## with an amino compound of the formula ##STR3## to produce a compound of the formula ##STR4## reacting the compound of the formula (III) with a compound of the formula ##STR5## to give a compound of the formula ##STR6## and then eliminating the amino-protective group ##STR7##
Type:
Grant
Filed:
June 19, 1991
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Uwe Petersen, Andreas Krebs, Thomas Schenke, Klaus Grohe, Michael Schriewer, Ingo Haller, Karl Georg Metzger, Rainer Endermann, Hans-Joachim Zeiler
Abstract: A process has been found for the preparation of dialkyl maleates from maleic acid, maleic anhydride or monoalkyl maleates with C.sub.1 -C.sub.8 -alcohols, in particular ethanol, in the presence or absence of an acidic catalyst and at boiling heat, which is characterized in that the escaping water/alcohol/vapour mixture, together with its condensed phase if appropriate, is conducted as feed along a hydrophilic membrane at which it is purged of water and the dehydrated alcohol is returned to the reaction mixture.
Type:
Grant
Filed:
June 2, 1995
Date of Patent:
July 15, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Nikolaus Muller, Andreas Groschl, Ingo Janisch
Abstract: The present invention relates to the preparation of novel vector systems which are generated by in-vitro recombination, using gene technology, of nucleic acids from foamy virus species and of exogenous nucleic acid, and are produced by suitable host cells or by recombinantly altered packaging cell lines. The recombinant preparation of particularly suitable packaging cell lines is likewise a constituent of this invention. The invention is distinguished by the safe and efficient transfer by foamy virus vectors of therapeutic and other genes into eukaryotic cells.
Abstract: The present invention relates to novel pseudopeptides with antiviral activity of the general formula (I) ##STR1## in which the substituents have the meaning given in the description, to a process for their preparation, and to their use as antiviral agents, especially against cytomegaloviruses.
Type:
Grant
Filed:
September 7, 1994
Date of Patent:
July 8, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Dieter Habich, Thomas-J. Schulze, Jurgen Reefschlager, Jutta Hansen, Rainer Neumann, Gert Streissle, Arnold Paessens
Abstract: The present invention relates to the new use of 1-alkyl-3,5-diacyl-1,4-dihydropyridines which are known in some cases, of the general formula (I) ##STR1## in which R.sup.1 to R.sup.4 have the meaning indicated in the description, processes for their preparation and their use as medicaments, as selective potassium channel modulators, in particular for the treatment of the central nervous system.
Type:
Grant
Filed:
December 8, 1995
Date of Patent:
July 8, 1997
Assignee:
Bayer Aktiengesellschaft
Inventors:
Klaus Urbahns, Hans-Georg Heine, Thomas Glaser, Reilinde Wittka, Jean-Marie-Viktor De Vry, Henning Sommermeyer