Patents Represented by Attorney Stephen B. Davis

Find this attorney in the Justia Lawyer Directory

  • Ostomy pouch with deodorizing filter
    Patent number: 4490145
    Abstract: An ostomy pouch having a filter element affixed to the outer pouch wall. The outer pouch wall has an aperture and the filter element includes a polymeric film cover and an insert of gas deodorizing material. The film cover also has an aperture and opposite ends of the insert overlie the two apertures.
    Type: Grant
    Filed: June 27, 1983
    Date of Patent: December 25, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Randolph E. Campbell
  • Enkephalinase inhibitors
    Patent number: 4474799
    Abstract: The degradation of enkephalins in a mammalian host is inhibited by administration of an enkephalinase enzyme inhibitor of the formula ##STR1##
    Type: Grant
    Filed: May 27, 1983
    Date of Patent: October 2, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Roland Greenberg, David W. Cushman, B. Richard Vogt, Frank L. Weisenborn, Michael J. Antonaccio
  • Enkephalinase inhibitors
    Patent number: 4474795
    Abstract: The degradation of enkephalins in a mammalian host is inhibited by administration of an enkephalinase enzyme inhibitor of the formula ##STR1##
    Type: Grant
    Filed: May 27, 1983
    Date of Patent: October 2, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Roland Greenberg, David W. Cushman, B. Richard Vogt, Frank L. Weisenborn, Michael J. Antonaccio
  • Lactam containing compounds, their pharmaceutical compositions and method of use
    Patent number: 4474778
    Abstract: Compounds of the formula ##STR1## are disclosed wherein R is ##STR2## The compounds possess hypotensive activity.
    Type: Grant
    Filed: November 9, 1983
    Date of Patent: October 2, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Eric M. Gordon, Donald S. Karanewsky
  • Substituted peptide compounds
    Patent number: 4470973
    Abstract: Substituted peptide compounds of the formula ##STR1## are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity and depending upon the definition of X may also be useful as analgesics due to their enkephalinase inhibition activity.
    Type: Grant
    Filed: June 2, 1983
    Date of Patent: September 11, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Sesha I. Natarajan, Eric M. Gordon
  • Closures for open ended ostomy pouch
    Patent number: 4465486
    Abstract: An open ended ostomy pouch having a folding bar attached to the bottom of the pouch. The folding bar extends on both sides beyond the width of the pouch at the bottom opening and includes interlocking closure components on opposite ends.
    Type: Grant
    Filed: September 30, 1982
    Date of Patent: August 14, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: John A. Hill
  • Carboxyalkyl amino acid derivatives of various substituted prolines
    Patent number: 4462943
    Abstract: Carboxyalkyl dipeptides of the formula ##STR1## wherein R.sub.4 is a 3-, 4-, 5-, or 4,4-substituted proline are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
    Type: Grant
    Filed: September 28, 1981
    Date of Patent: July 31, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Edward W. Petrillo, Jr., Eric M. Gordon, John Krapcho, Peter W. Sprague
  • Iminothiazolyl ureido cephalosporins
    Patent number: 4461767
    Abstract: Cephalosporins of the formula ##STR1## wherein R is hydrogen, sodium, potassium or certain ester groups; R.sub.1 is in the .alpha.-configuration and is hydrogen or methoxy; R.sub.2 is hydrogen, ##STR2## R.sub.4 is hydrogen or lower alkyl; R.sub.5 is hydrogen, lower alkyl, ##STR3## or --(CH.sub.2).sub.n --N--(lower alkyl).sub.2 ; R.sub.6 is hydrogen, sodium, or potassium; n is an integer from 1 to 4; are disclosed. These compounds are useful as anti-bacterial agents.
    Type: Grant
    Filed: June 6, 1979
    Date of Patent: July 24, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Hermann Breuer, Uwe D. Treuner, Theodor Denzel
  • Thiazine and thiazepine containing compounds
    Patent number: 4460579
    Abstract: This invention is directed to compounds of the formula ##STR1## wherein X is a thiazine or thiazepine selected from ##STR2## These compounds possess angiotensin converting enzyme inhibition activity and are thus useful as hypotensive agents.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: July 17, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Donald S. Karanewsky
  • Ostomy bag
    Patent number: 4460363
    Abstract: A system is provided by which an ostomy bag can be securely coupled to an adhesive dressing that fits around the stoma and yet will permit the bag to be removed without disturbing the dressing. This system involves a first coupling member bonded to the dressing and a second coupling member bonded to the ostomy bag around the stomal opening. One coupling member consists of an upstanding rib or other projection which is dimensioned to sealingly engage an opening in the other coupling member.
    Type: Grant
    Filed: July 2, 1982
    Date of Patent: July 17, 1984
    Assignee: Kingsdown Medical Consultants, Ltd.
    Inventors: Peter L. Steer, John V. Edwards
  • 4-Substituted dehydroprolines
    Patent number: 4456761
    Abstract: Compounds of the formula ##STR1## are useful as intermediates in the preparation of various hypotensive agents.
    Type: Grant
    Filed: July 29, 1982
    Date of Patent: June 26, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: John Krapcho
  • Carboxy and substituted carboxy aroly peptides
    Patent number: 4456595
    Abstract: Peptides of the formula ##STR1## wherein X is various amino or imino acids or esters are useful as hypotensive agents.
    Type: Grant
    Filed: December 6, 1982
    Date of Patent: June 26, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Harold N. Weller, III, Eric M. Gordon
  • Phosphinylmethylaminocarbonyl imino acid compounds useful for treating hypertension
    Patent number: 4448772
    Abstract: This invention is directed to phosphinylmethylaminocarbonyl imino acid compounds of the formula ##STR1## wherein X represents various unsubstituted or substituted imino acids or esters.
    Type: Grant
    Filed: April 22, 1982
    Date of Patent: May 15, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Donald S. Karanewsky
  • Phosphonamidate compounds
    Patent number: 4432972
    Abstract: Phosphonamidates of the formula ##STR1## wherein X is an amino acid or ester. These compounds possess angiotensin converting enzyme inhibition activity and enkephalinase inhibition activity. Thus they are useful as hypotensive and analgesic agents.
    Type: Grant
    Filed: December 27, 1982
    Date of Patent: February 21, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Donald S. Karanewsky, Edward W. Petrillo, Jr.
  • Phosphonamidate compounds
    Patent number: 4432971
    Abstract: Phosphonamidates of the formula ##STR1## wherein X is a substituted or unsubstituted imino or amino acid or ester. These compounds possess angiotensin converting enzyme activity and are thus useful as hypotensive agents.
    Type: Grant
    Filed: June 28, 1982
    Date of Patent: February 21, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Donald S. Karanewsky, Edward W. Petrillo, Jr.
  • Microporous adhesive tape
    Patent number: 4427737
    Abstract: A breathable tape comprising a porous backing layer and a microporous adhesive layer. The adhesive layer includes a rubbery elastomer, one or more water soluble or swellable hydrocolloids, and other optional substances and has a porosity of from about 1 to about 100 cc/sec/in.sup.2.
    Type: Grant
    Filed: April 23, 1981
    Date of Patent: January 24, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Rudolfo D. Cilento, Charles Riffkin, Anthony L. LaVia
  • Phosphinylalkanoyl substituted imino acids and their use in hypotensive compositions
    Patent number: 4427665
    Abstract: Phosphinylalkanoyl imino acids of the formula ##STR1## wherein X is tetrahydroisoquinoline carboxylic acid, dihydroindole or dihydroisoindole carboxylic acid are disclosed. These compounds are useful as hypotensive agents due to their angiotensin converting enzyme inhibition activity.
    Type: Grant
    Filed: May 19, 1982
    Date of Patent: January 24, 1984
    Assignee: E. R. Squibb & Sons, Inc.
    Inventors: Donald S. Karanewsky, Edward W. Petrillo, Jr.
  • Female incontinence device
    Patent number: 4421511
    Abstract: A female incontinence device comprising an external resilient pad that makes sealing engagement with the user's anatomy that is external to the labia majora and a funnel having a rim dimensioned to engage that portion of the user's anatomy immediately surrounding the meatus of the urethra. The funnel is mounted to the pad, formed as part of the pad, or dimensioned to fit through an opening in the pad.
    Type: Grant
    Filed: February 25, 1981
    Date of Patent: December 20, 1983
    Assignee: Craig Medical Products Limited
    Inventors: Peter L. Steer, John V. Edwards
  • Apparatus for manufacturing ostomy pouches
    Patent number: 4419174
    Abstract: Ostomy pouches are manufactured by partially contour welding two pouch walls one of which has a stoma aperture over an area extending from the top edge of the pouch past the region of the weld seam around the aperture. A separator member is inserted into the partially welded pouch and an adhesive label is then welded or bonded to the pouch wall around the aperture. The separator member is withdrawn and the contour welding is completed to form the completed pouch.
    Type: Grant
    Filed: February 28, 1983
    Date of Patent: December 6, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Ole R. Jensen
  • Amino and substituted amino phosphinylalkanoyl compounds
    Patent number: 4416831
    Abstract: Compounds of the formula ##STR1## wherein X is an imino acid or ester and R.sub.1 is hydrogen, ##STR2## are useful hypotensive agents due to their angiotensin converting enzyme inhibition activity.
    Type: Grant
    Filed: November 1, 1982
    Date of Patent: November 22, 1983
    Assignee: E. R. Squibb & Sons, Inc.
    Inventor: Edward W. Petrillo, Jr.