Patents Assigned to 1
  • Heart assist device with expandable impeller pump
    Patent number: 11708833
    Abstract: An impeller includes a hub and a blade supported by the hub. The impeller has a stored configuration in which the blade is compressed so that its distal end moves towards the hub, and a deployed configuration in which the blade extends away from the hub. The impeller may be part of a pump for pumping fluids, such as blood, and may include a cannula having a proximal portion with a fixed diameter, and a distal portion with an expandable diameter. The impeller may reside in the expandable portion of the cannula. The cannula may have a compressed diameter which allows it to be inserted percutaneously into a patient. Once at a desired location, the expandable portion of the cannula may be expanded and the impeller expanded to the deployed configuration. A flexible drive shaft may extend through the cannula for rotationally driving the impeller within the patient.
    Type: Grant
    Filed: October 30, 2020
    Date of Patent: July 25, 2023
    Assignees: The Penn State Research Foundation, TC1 LLC
    Inventors: Mark W. McBride, Thomas M. Mallison, Gregory P. Dillon, Robert L. Campbell, David A. Boger, Stephen A. Hambric, Robert F. Kunz, James P. Runt, Justin M. Walsh, Boris Leschinsky
  • Use of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide in the treatment of acute exacerbations of chronic obstructive pulmonary disease
    Patent number: 11701341
    Abstract: The invention relates to pharmaceutical compositions comprising 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide for use in the treatment of acute exacerbations of chronic obstructive pulmonary disease in human patients having <2% blood eosinophils. The invention also relates to pharmaceutical compositions for the treatment of AECOPD in a human patient having <2% blood eosinophils, comprising administering to the patient three separate therapeutically effective doses of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-N-cyclopropyl-4-methylbenzamide over a period of not longer than ten days with at least one day between every dose.
    Type: Grant
    Filed: December 11, 2018
    Date of Patent: July 18, 2023
    Assignee: MEREO BIOPHARMA 1 LIMITED
    Inventors: Alastair MacKinnon, Jacqueline Parkin
  • Hydrogen generation assemblies and hydrogen purification devices
    Patent number: 11701624
    Abstract: Hydrogen generation assemblies, hydrogen purification devices, and their components, and methods of manufacturing those assemblies, devices, and components are disclosed. In some embodiments, the devices may include an insulation base having insulating material and at least one passage that extends through the insulating material. In some embodiments, the at least one passage may be in fluid communication with a combustion region.
    Type: Grant
    Filed: June 17, 2022
    Date of Patent: July 18, 2023
    Assignee: Element 1 Corp
    Inventor: David J Edlund
  • Wireless resonant circuit and variable inductance vascular monitoring implants and anchoring structures therefore
    Patent number: 11701018
    Abstract: Wireless, variable inductance and resonant circuit-based vascular monitoring devices, systems, methodologies, and techniques, including specifically configured anchoring structures for same, are disclosed that can be used to assist healthcare professionals in predicting, preventing, and diagnosing various heart-related and other health conditions.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: July 18, 2023
    Assignee: Foundry Innovation & Research 1, Ltd.
    Inventors: Fiachra M. Sweeney, Hanson S. Gifford, III, Jessi Johnson, Pablo Martin, Stephen Sheridan, Douglas S. Sutton, Friedrich Wetterling, Conor M. Hanley
  • Method to additive manufacture biocompatible material and articles made by the method
    Patent number: 11697242
    Abstract: A method of additive manufacturing is comprised of providing a material comprised of a ethyl cellulose polymer having an ethoxy content of 43% to 52% by mass and a plasticizer. The material is heated and dispensed through a nozzle to form an extrudate deposited on a base. The base, nozzle or combination thereof is moved while dispensing the material so that there is horizontal displacement between the base and nozzle in a predetermined pattern to form an initial layer of the material on the base and successive layers of the material are adhered on the initial layer to form an additive manufactured part by repeating the aforementioned steps. The article formed of the ethyl cellulose polymer may be used in many applications such as those related to the pharmaceutical and food industries.
    Type: Grant
    Filed: July 20, 2016
    Date of Patent: July 11, 2023
    Assignee: Nutrition & Biosciences USA 1, LLC
    Inventors: Roland Bayer, Aleksander J. Pyzik, Sharon Allen, Scott T. Matteucci
  • Anti-IL17A autoantibodies for treating or reducing the likelihood of occurrence of bone destruction associated with a chronic autoimmune or inflammatory disease
    Patent number: 11693003
    Abstract: The present invention relates to an in vitro method for evaluating the prognosis of an autoimmune or chronic inflammatory disease in an individual, comprising the following steps: a) determining (i) the level of an anti-IL-17 autoantibody and/or (ii) the level of an [IL-17/anti-IL-17 autoantibody] complex in a biological sample of the individual, and b) comparing the level of autoantibody and/or of complex determined in step a) with a reference value, the comparison being indicative of the prognosis of an autoimmune or chronic inflammatory disease in said individual.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: July 4, 2023
    Assignees: Hospices Civil de Lyon, Universite Claude Bernard Lyon 1, Eurobio Scientific
    Inventors: Pierre Miossec, Ndieme Thiam, Jean-Jacques Pin
  • Introducer sheath assembly for catheter systems and methods of using same
    Patent number: 11690606
    Abstract: A catheter system includes a catheter including an elongate body having an expandable medical device coupled with a distal end thereof, and an introducer sheath assembly disposed over a proximal section of the catheter. The introducer sheath assembly includes an introducer sheath disposed over the catheter to form a gap therebetween, and a tubular plug. The introducer sheath includes an elongate body extending from a proximal end to a distal end and defining a lumen therein. The tubular plug extends through the lumen and includes an elongate body extending from a proximal end to a distal end that protrudes from the introducer sheath distal end. The plug is disposed between the catheter and the introducer sheath to occlude the gap. The plug is releasably fixed relative to the introducer sheath such that the plug is removable from the lumen to allow the expandable medical device to pass therethrough.
    Type: Grant
    Filed: May 1, 2020
    Date of Patent: July 4, 2023
    Assignee: TC1 LLC
    Inventors: Paul Muller, Keif Fitzgerald, Ted Su, Michael Butler
  • ACCESS MANAGEMENT SYSTEM
    Publication number: 20230206708
    Abstract: An access management system includes a mobile device with a processor and a memory and a software platform including at least a processor and a memory. The software platform is configured to analyze data obtained from the mobile device and other devices connected to the software platform. Specifically, the software platform is operable to determine if an access key received, read, or captured by a mobile device matches an access key for an authorized account, object, device, or space for the mobile device, and to provide access to the mobile device if the access key received, read, or captured by the mobile device matches the authorized access key.
    Type: Application
    Filed: March 3, 2023
    Publication date: June 29, 2023
    Applicant: 1AHEAD Technologies
    Inventor: Ronald Carter
  • Flexible tensile member with releasable convolutions for absorbing tensile energy
    Patent number: 11686363
    Abstract: An energy absorber includes a flexible tensile member having lengthwise sections arranged serially along a length of the flexible tensile member. Lengthwise sections define convolutions. Features are provided for both restricting straightening of the convolutions and automatically reconfiguring, in response predetermined tension in the flexible tensile member, to allow straightening of the convolutions.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: June 27, 2023
    Assignee: Barrier1 Systems, LLC
    Inventor: Michael John Lamore
  • P2Xand/or P2Xcompounds and methods
    Patent number: 11685736
    Abstract: The present application provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R4 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient.
    Type: Grant
    Filed: December 5, 2019
    Date of Patent: June 27, 2023
    Assignee: ABS Development 1, Inc.
    Inventors: Scott K. Thompson, Aranapakam Venkatesan, Tony Priestley, Mrinal Kundu, Ashis Saha
  • Multilayer identification patches
    Patent number: 11685181
    Abstract: A multilayer identification patch comprises a reflective layer and a design layer on top of the reflective layer. The design layer comprises an opaque body and at least one identification symbol void (ISV) to allow light to reflect from a portion of the reflective layer via the ISV. The opaque body of the design layer comprises multiple layers of cured photopolymer ink. The multiple layers of cured photopolymer ink comprise an opaque layer of colored photopolymer ink. In one embodiment, the multiple layers of cured photopolymer ink in the opaque body of the design layer further comprise a layer of clear photopolymer ink under the opaque layer of colored photopolymer ink. Other embodiments are described and claimed.
    Type: Grant
    Filed: April 5, 2022
    Date of Patent: June 27, 2023
    Assignee: Tier 1 Transnational LLC
    Inventors: Michael D. Holcombe, Christopher J. Hart, Trey L. Stach, Colleen P. Hart
  • Implantable blood pump assembly including pressure sensor and methods of assembling same
    Patent number: 11684769
    Abstract: Disclosed herein is an implantable blood pump assembly that includes a housing defining an inlet, an outlet, a flow path extending from the inlet to the outlet, and an internal compartment separated from the flow path. The blood pump assembly further includes a rotor positioned within the flow path and operable to pump blood from the inlet to the outlet, a stator positioned within the internal compartment and operable to drive the rotor, and an inlet conduit connected to the housing inlet and having a downstream end that has a reduced cross-sectional area that produces a localized region of high velocity blood flow. The blood pump assembly further includes at least one pressure sensor positioned between the inlet and the outlet and configured to detect a pressure of blood flowing through the flow path. The pressure sensor is located adjacent the downstream end of the inlet conduit.
    Type: Grant
    Filed: December 19, 2019
    Date of Patent: June 27, 2023
    Assignee: TC1 LLC
    Inventors: Daniel I. Harjes, Eric Lee, Jin Woo Park
  • Artificial cells and delivery devices for use in tissue engineering, and related methods
    Patent number: 11684574
    Abstract: Provided herein is a drug delivery device and composition, such as a particle, comprising conditioned medium. Also provided herein is a method of preparing polymeric particles for release of conditioned medium. Further, a tissue growth scaffold comprising particles for release of conditioned medium is provided.
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: June 27, 2023
    Assignees: University of Pittsburgh—Of the Commonwealth System of Higher Education, Svstem of Higher Education 1tts
    Inventors: Morgan Virginia Fedorchak, Jeffrey Krawiec, Steven R. Little, Katherine Lorentz, David A. Vorp, Justin Weinbaum
  • Implantable wireless pressure sensor
    Patent number: 11684276
    Abstract: An implantable wireless sensor is provided for determining a pressure of a lumen in a body. The sensor comprises a sensor body comprising a plurality of substrates, at least a portion of the substrates comprising a first dielectric material. An LC resonant circuit is contained with the sensor body. A capacitance of the LC resonant circuit is configured to vary in response to changes in pressure in the lumen. A first anchoring element is coupled to a proximal end of the sensor body and a second anchoring element is coupled to a distal end of the sensor body. The first and second anchoring elements are configured to lodge the sensor body within the lumen. A second dielectric material, different than the first dielectric material, is provided over at least a portion of at least one of the plurality of substrates.
    Type: Grant
    Filed: August 13, 2021
    Date of Patent: June 27, 2023
    Assignee: TC1, LLC
    Inventors: Florent Cros, David O'Brien, Michael Fonseca, Matthew Abercrombie, Jin Woo Park, Angad Singh
  • Methods and systems for electrical system monitoring and/or control
    Patent number: 11689011
    Abstract: A method of dedicated circuit verification using a monitoring system includes measuring current at circuit breaker, comparing breaker current with microinverter current generated from one or more solar panels and determining whether they are within a threshold amount of one another, and generating an output based on the comparison.
    Type: Grant
    Filed: September 23, 2020
    Date of Patent: June 27, 2023
    Assignee: 1st Step Solar
    Inventor: Paul Pursifull
  • Mechanical gauge for estimating inductance changes in resonant power transfer systems with flexible coils for use with implanted medical devices
    Patent number: 11689057
    Abstract: Systems, devices, and methods for improving wireless power transmission are disclosed herein. A method of powering an implantable ventricular assist device with an external charging device includes receiving a signal indicative of a change in a property of a deformable coil of the resonant circuit. A performance property of the deformable coil is determined based on the signal. An adjustment to a tuning of the resonant circuit is identified based on the performance property of the deformable coil. The resonant circuit is tuned according to the adjustment to the tuning of the resonant circuit. The resonant circuit is driven to transmit power to a secondary coil electrically coupled with the implantable ventricular assist device to power the ventricular assist device.
    Type: Grant
    Filed: February 3, 2021
    Date of Patent: June 27, 2023
    Assignee: TC1 LLC
    Inventor: John Freddy Hansen
  • Upholstery support arrangement, including airflow arrays for conditioned furniture, and associated systems and methods
    Patent number: 11678748
    Abstract: Upholstery support arrangements for conditioned furniture are disclosed herein. A representative arrangement, such as for a ventilated bed, comprises an upholstery support structure having a support platform that defines a support plane, for supporting an upholstery item, the upholstery support platform having a first array of apertures that allow a flow of air through the support platform; the upholstery supported on the support platform (e.g., a mattress) having a bottom face facing the support platform and including a second array of apertures positioned to allow the flow of air through the bottom face into the upholstery; wherein a periodicity of the first array of apertures and a periodicity of the second array of apertures are matched to one another.
    Type: Grant
    Filed: March 10, 2021
    Date of Patent: June 20, 2023
    Assignee: Pure-Development 1 B.V.
    Inventors: Barry Van Doornewaard, Michiel Maria Augustinus Steegmans
  • Percutaneous heart pump transitionable between separated and operational configurations
    Patent number: 11679234
    Abstract: Disclosed herein is a catheter pump that includes an expandable cannula and an impeller system. The expandable cannula defines a blood flow channel and includes an impeller blade zone, an inlet zone, and an outlet zone. The catheter pump further includes an impeller system including an impeller body, the impeller system movable relative to the expandable cannula along a longitudinal axis of the catheter pump. The catheter pump is selectively transitionable between a separated configuration in which the impeller body is axially spaced from the expandable cannula along the longitudinal axis, and an operational configuration in which the impeller body is positioned within the impeller blade zone of the expandable cannula.
    Type: Grant
    Filed: October 29, 2020
    Date of Patent: June 20, 2023
    Assignee: TC1 LLC
    Inventors: Alexander King, David Panus, Tracee Eidenschink, John Pocrnich, Kevin Griffin
  • Remote control
    Patent number: D989744
    Type: Grant
    Filed: April 7, 2021
    Date of Patent: June 20, 2023
    Assignee: Pure-Development 1 B.V.
    Inventor: Barry van Doornewaard
  • Sole for a shoe
    Patent number: D992261
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: July 18, 2023
    Assignee: FRANKIE4 IP 1 PTY LTD
    Inventor: Caroline Rose Haire