Abstract: A therapy apparatus for treating tissue by emission of focused ultrasound waves, including: a creation surface of a pressure field of focused ultrasound waves divided into at least N sectors having segments of asymmetrical concave curve with centres of curvature; centres of curvature asymmetrical to the extent where the centres of curvature are situated at different distances from the plane of symmetry or from at least one of the axis of symmetry and at different depths taken according to the axis of symmetry; the individual axes intersecting between the focal zones and the creation surface or beyond the focal zones such that the beams originating from the sectors intersect to create a focal coverage zone which is off-axis relative to the plane of symmetry or to the axis of symmetry; the sectors of this creation surface creating energy deposit zones with profiles corresponding to the focal coverage zones.

Abstract: A method is disclosed for solving the Lagrangian dual of a constrained binary quadratic programming problem. The method comprises obtaining a constrained quadratic binary programming problem; until a convergence is detected, iteratively, performing a Lagrangian relaxation of the constrained quadratic binary programming problem to provide an unconstrained quadratic binary programming problem, providing the unconstrained quadratic binary programming problem to a quantum annealer, obtaining from the quantum annealer at least one corresponding solution, using the at least one corresponding solution to generate a new approximation for the Lagrangian dual bound; and providing a corresponding solution to the Lagrangian dual of the constrained binary quadratic programming problem after convergence.

Abstract: The present invention relates to new transcriptional promoters that are functional during meiosis. It thus provides new tools, methods and compositions for the expression of proteins during meiosis in a eukaryotic cell, and more particularly in a plant cell.

Abstract: A method, apparatus, and system of pause and replay of media content through bookmarks on a server device are disclosed. In one embodiment, a method of a server device includes authenticating a user of a client device, communicating a media content to the client device through a network, processing a pause request of the client device to pause the media content, storing a bookmark location indicating a current playback location of the media content in the client device on the server device, processing a play request of the user to play the media content from the bookmark location (e.g., the play request may be received from a different client device of the user), and communicating the media content from the bookmark location to the user.

Abstract: Hazard-resultant effects to land and buildings are predicted based on various inputs. Hazards may include any appropriate type of hazard (e.g., flood, wildfire, climate-related hazards, or the like). Inputs may include the likelihood that that a specific type of hazard may occur for various scenarios, terrestrial boundaries, property boundaries, census geographies, or the like. Relationships between the inputs are determined and used to quantify parameters pertaining to a specific type of hazard. For example, the depth of flood water may be predicted for a particular terrestrial boundary, a city or town, or a building, for specific climate scenarios. A risk likelihood of the quantified parameter may be determined for a particular period of time and environment. For example, flooding to a building may be determined, broken down by depth threshold and year of annual risk for specific climate scenarios. Economic loss also may be predicted.

Abstract: A bicycle includes a frame, a storage compartment, a battery pack, a pedal assist unit, and a lighting system. The frame includes a head tube, a stem, a down tube, a central hub, and a pair of chain stays. The central hub defines an internal cavity. The down tube and the central hub cooperatively define a battery opening connected to the internal cavity. The storage compartment includes a door positioned to selectively enclose an opening in the down tube. The battery pack is releasably received by the battery opening. The pedal assist unit is disposed within the internal cavity. The lighting system includes one or more taillights integrated into the chain stays, a conspicuity lamp integrated into the head tube, and/or a headlight integrated into to at least one of the stem or the head tube.

Abstract: Various aspects of the disclosure relate to using a verifiable and distributed encoding as a digital currency (e.g., cryptocurrency). According to some embodiments, systems and methods can be executed to transfer cash or “hard” currency responsive to exchange of cryptocurrency supported by blockchain technology. In further example, the systems and methods are tailored to operate within a specified/defined community that ensures the efficient operation of the system by ensuring liquidity of the transfer. According to one embodiment, the system is configured to distribute stable coin, issuing the coin at a discounted value (e.g., relative to a redemption or cash equivalent face value). For example, by issuing coin at a discount the system automatically facilitates peer-to-peer physical cash transfers.

Abstract: An interpolated position of an incremental encoder is provided. A first signal and a second signal having a quadrature relationship are received from the incremental encoder. A coarse position of the incremental encoder at a first time is produced using the quadrature relationship between the first signal and the second signal. An arcsine or arccosine value based on the first signal at the first time is determined using a lookup table and a fine position of the incremental encoder is calculated using the determined value. The interpolated position of the incremental encoder, based on both the coarse position and the fine position, is then provided.

Abstract: A catheter pump assembly is provided that includes an elongate body, an elongate flexible shaft disposed in the elongate body, and an impeller coupled with the distal end of the elongate flexible shaft. The drive system includes a drive component, a motor and a tension member. The tension member is coupled with the motor and the drive component and to cause the drive component to rotate, and thereby to cause the impeller to rotate.

Abstract: An artificial intelligence entry management device for an entry and delivery system includes a camera, a microphone, a motion detector, a speaker, and a housing. The housing has an oval shape with a substantially open middle. The substantially open middle has a housing protrusion portion configured to house the camera, the microphone, the motion detector, and the speaker. The entry and delivery system may also include one or more robots that interface with the entry management device to monitor an area around an access point and to alert the user of activity. A robot may be an aerial robot that has a camera, a robot light, a speaker, a microphone and an actuator to enable picking and moving a package. Aerial robots may be configured around a perimeter of a building to monitor the building and may turn on a robot light when motion is detected.

Abstract: A jammed gel bioink comprises a self-assembling peptide solution comprising a self-assembling peptide, and a cell solution comprising living cells and a cell culture medium. The self-assembling peptide solution is extruded to form an object, and then the cell solution is injected into the object. Useful methods of making the jammed gel bioink are also disclosed.

Abstract: Disinfectors that are touchless, high speed, or both for personal electronic devices and the like. A housing defines an internal volume including a disinfection zone and an object entry port of a size to permit entry by an object of interest with exposed surface area. At least one emitter projects a stripe of UV-C light into the disinfection zone. Wherein the apparatus has a small footprint and the emitter to exposes the surface area to greater than 3 mJ/cm2 of UV-C light in less than 90 seconds.

Abstract: A bioink comprises a cell solution comprising living cells and a cell culture medium, and a self-assembling peptide solution comprising a self-assembling peptide. The bioink is formed by mixing and extruding the cell solution and the self-assembling peptide solution together, and the bioink can be continuously extruded from the mixer after mixing. Useful methods of making bioinks and are also disclosed.

Abstract: A barrier apparatus includes a barrier post mounted to a base and extending upwardly from the base. A brace of the barrier apparatus is configured to restrict relative movement between the barrier post and the base. The brace can be mounted to the base so that it extends upwardly and obliquely toward the barrier post. The brace can include block. A reinforcing tube can extend around the block. A mated connection to the front of the brace can include a first mating protrusion extending into a first mating hole, and a mated connection to the bottom of the brace can include a second mating protrusion extending into a second mating hole. The brace or another brace can extend into a rear corner positioned between the barrier post and the base.

Abstract: The invention generally relates to heart pump systems. In some embodiments, a pressure sensor is provided with a heart pump, either at the inflow or the outflow of the blood pump. The heart pump may further include a flow estimator based on a rotor drive current signal delivered to the rotor. Based on the rotor drive current signal, a differential pressure across the pump may be calculated. The differential pressure in combination with the pressure measurements from the pressure sensor may be used to calculate pressure on the opposite side of the pump from the pressure sensor. In some embodiments, the pressure sensor is located at the outflow of the pump and the pump is coupled with the left ventricle. The differential pressure and pressure measurement may be used to calculate a left ventricular pressure waveform of the patient. With such a measurement, other physiological parameters may be derived.

Abstract: A blood pump system includes a pump housing and an impeller for rotating in a pump chamber within the housing. The impeller has a first side and a second side opposite the first side. The system includes a stator having drive coils for applying a torque to the impeller and at least one bearing mechanism for suspending the impeller within the pump chamber. The system includes a position control mechanism for moving the impeller in an axial direction within the pump chamber to adjust a size of a first gap and a size of a second gap, thereby controlling a washout rate at each of the first gap and the second gap. The first gap is defined by a distance between the first side and the housing and the second gap is defined by a distance between the second side and the pump housing.

Abstract: A proton exchange solid support includes a first solid support including a polymer, a second solid support, and a tetravalent boron-based acid group that links the first solid support to the second solid support.

Abstract: An implantable sensor for implantation in a vessel, comprising a plurality of electrodes for placement on, in or adjacent a vessel wall, means for providing a drive signal to the electrodes, means for measuring at least one of impedance and capacitance between at least two of the plurality of electrodes, and means for wirelessly communicating data from the sensor and a blood vessel monitoring system comprising same.

Abstract: A method and apparatus for providing hybrid draw poker games to online players, poker hands comprise both physical card values dealt by a dealer and electronically-generated card values from the gaming server. The gaming server receives an indication from each of the remote players of how many hands each player would like to play, and a wager amount for each hand. Electronic indications of an initial set of physical cards dealt by the dealer are then provided to the online players. In response, each player provides an indication of card values that each player would like to retain and/or an indication of card values that each player would like to discard. The gaming server assigns the retained card values selected by each player to each player's respective hands, and then generates electronic replacement card values for each hand of each player. The gaming server then performs a win/lose analysis for each hand.

Abstract: The present invention relates to a composite form of tetraacetylethylenediamine (TAED) and a method for its preparation. The composite form may comprise a new crystalline form. The invention also relates to the crystalline form itself. The present invention also relates to compositions comprising tetraacetylethylenediamine in these forms.