Abstract: A cementitious composition, including for the molding of relatively light-weight, heat-insulative, nailable, structural units such as bricks, blocks, roof decking, etc. The composition may include an inorganic cementitious settable admixture within which is incorporated a significant proportion of waste industrial products, such as concrete, blacktop, windmill blades, brick chips, plastics, cordierite, tires, stack dust and/or fly ash, ceramics, clays, metals and plastics. The waste industrial products may be incorporated into the composition in various proportions.

Abstract: A modular building unit for construction of a building comprises a structural frame 40 suitable for interconnection to another modular building unit in construction of the building; and a stud frame wall 80/82 internal to and fixed to the frame. The modular building unit is suitable for handling as a shipping container for transport.

Abstract: A tissue core sample in a metal core collector or stylet is touched to a substrate channel filled with as special liquid such as a hydrogel to which the tissue core sample is attracted to thereby transfer the tissue sample to the channel while preserving the integrity of the sample, speeding up the transfer and preserving the sample orientation so it can be unambiguously associated with its anatomical origin.

Abstract: A set of servers can support secure and efficient “Machine to Machine” communications using an application interface and a module controller. The set of servers can record data for a plurality of modules in a shared module database. The set of servers can (i) access the Internet to communicate with a module using a module identity, (i) receive server instructions, and (iii) send module instructions. Data can be encrypted and decrypted using a set of cryptographic algorithms and a set of cryptographic parameters. The set of servers can (i) receive a module public key with a module identity, (ii) authenticate the module public key, and (iii) receive a subsequent series of module public keys derived by the module with a module identity. The application interface can use a first server private key and the module controller can use a second server private key.

Abstract: A method, related device and system for lifting a reservoir fluid in an oil and gas well involves allowing the reservoir fluid to flow in an axial uphole direction through an internal flow path of a production tubing disposed in the well. The internal flow path includes a Venturi profile configured to flash out a free gas phase from the reservoir fluid as the reservoir fluid flows in the axial uphole direction through the Venturi profile, such that the reservoir fluid comprises the free gas phase and a liquid phase. The internal flow path also includes a diffusion profile disposed above the Venturi profile and configured to condense the free gas phase into the liquid phase as the reservoir fluid flows in axial uphole direction through the diffusion profile.

Abstract: Methods and systems are provided for supporting efficient and secure “Machine-to-Machine” (M2M) communications using a module, a server, and an application. A module can communicate with the server by accessing the Internet, and the module can include a sensor and/or an actuator. The module, server, and application can utilize public key infrastructure (PKI) such as public keys and private keys. The module can internally derive pairs of private/public keys using cryptographic algorithms and a first set of parameters. A server can authenticate the submission of derived public keys and an associated module identity. The server can use a first server private key and a second set of parameters to (i) send module data to the application and (ii) receive module instructions from the application. The server can use a second server private key and the first set of parameters to communicate with the module.

Abstract: A vehicle has steering and drive wheels supported by legs articulated to the structure of the vehicle. Each leg is rotatably mounted on a main support around a transverse axis. The main support is rotatably mounted about the transverse axis on a base structure, which is connected to the structure of the vehicle. An actuator device is operatively interposed between the main support and the base support to adjust the position of the main support around the transverse axis, and consequently the height of the vehicle from the ground. A hub-bearing support carrying the wheel hub is rotatably mounted around a wheel steering axis on an auxiliary camber adjustment support. The latter is carried around a camber adjustment axis on a further auxiliary caster adjustment support. The latter is carried by the leg around a caster adjustment axis. The steering of the wheel and the camber adjustment are controlled by respective actuator devices.

Abstract: The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for altering a target nucleic acid.

Abstract: The output voltage of an MRAM is increased by means of an Fe(001)/MgO(001)/Fe(001) MTJ device, which is formed by microfabrication of a sample prepared as follows: A single-crystalline MgO (001) substrate is prepared. An epitaxial Fe(001) lower electrode (a first electrode) is grown on a MgO(001) seed layer at room temperature, followed by annealing under ultrahigh vacuum. A MgO(001) barrier layer is epitaxially formed on the Fe(001) lower electrode (the first electrode) at room temperature, using a MgO electron-beam evaporation. A Fe(001) upper electrode (a second electrode) is then formed on the MgO(001) barrier layer at room temperature. This is successively followed by the deposition of a Co layer on the Fe(001) upper electrode (the second electrode). The Co layer is provided so as to increase the coercive force of the upper electrode in order to realize an antiparallel magnetization alignment.

Abstract: An electrode for a plasma reactor, the electrode comprising an elongate body having an inlet end and an opposed outlet end, a reaction region extending along a portion of the elongate body, a first sealing region located between the reaction region and the inlet end of the elongate body and a second sealing region located between the reaction region and the outlet end of the elongate body, wherein the first sealing region and the second sealing region each comprise a plurality of receiving portions adapted to receive a sealing member therein, and wherein a barrier member adapted to reduce or eliminate the flow of fluid between the receiving portions provided between each of the plurality of receiving portions.

Abstract: An optical structure comprising at least one stack having a central filter (1) and two sandwiching optical elements (2,3) between which the central filter (1) is interposed, wherein the central filter (1) is in a matrix material. The matrix material being doped with at least one doping agent, the central filter (1) and the two optical elements (2,3) on either side thereof being assembled by bonding layers (4a, 4b) of a material based on the same matrix material as that of the central filter, the optical elements (2,3) on either side of the central filter (1) and the bonding layers (4a, 4b) each having a refractive index equal to that of the material of the central filter or only differing from this refractive index within a range of plus or minus 0.05, preferably within a range of plus or minus 0.02.

Abstract: The present invention relates to a compound of the following general formula (I) or a pharmaceutically acceptable salt and/or solvate thereof, for use as drug for inhibiting ferroptosis.

Abstract: A process for preparing a catalyst material, includes: (a) providing a support material having surface hydroxyl (OH) groups, the support material is ceria (CeO2), zirconia (ZrO2) or a combination, and the support material contains between 0.3 and 2.0 mmol OH groups/g of the support material; (b) reacting the support material with at least one of: (b1) a compound containing at least one alkoxy or phenoxy group bound though its oxygen atom to a metal element from Group 5 (V, Nb, Ta) or Group 6 (Cr, Mo, W); (b2) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element from Group 5 or 6; (b3) a compound containing at least one hydrocarbon group bound though a carbon atom to a metal element which is copper (Cu); and (c) calcining the product obtained in step (b).

Abstract: The present invention provides SOCE inhibitors that are useful as therapeutic agents in a variety of applications. The present invention also relates to pharmaceutical compositions, products and kits comprising such SOCE inhibitors, and methods of using the SOCE inhibitors in the treatment of a variety of diseases.

Abstract: The invention relates to a backrest support for a seating furniture, in particular for an office chair. In order to provide a piece of seating furniture having a backrest, in the case of which particularly simple and safe installation and removal of the backrest is possible, it is proposed to design the backrest support (2) in two parts, having a first support part (4), which is connectable to a second support part (5) without a tool, with a releasable connection being formed, wherein, in the assembled state, the position of the two support parts (4, 5) with respect to each other can be secured without a tool by means of a lock (6).

Abstract: This disclosure sets out an apparatus for handling fluid, such as coolant, for a vehicle that is at least partially powered by electricity. The apparatus includes a substantially plate-shaped base element defining a base plane separating a first subspace from a second subspace. At least a first fluid flow channel section is also present and is largely located in the first subspace. At least one second fluid flow channel section is also present and is largely located in the second subspace. The base element includes at least one first flow-through opening fluidly connecting the first fluid flow channel section and the second fluid flow channel section. A method of manufacturing the apparatus is also disclosed. The method includes the steps of providing the base element with at least a first fluid flow channel section and a first flow-through opening.

Abstract: The present invention relates to a virus-derived particle comprising one or more Cas protein(s), as well as to kits and methods using the same for altering a target nucleic acid.

Abstract: Collimation device for an X-ray detection system, the collimation device comprising: a collimator comprising a substantially planar support made of a material with partial or zero radiotransparency, the support being rotatably movable about an axis of rotation (?) which passes through the support and which is perpendicular to a first face of the support which acts as an X-ray plane of incidence referred to as the main plane of the support (P), the support (D) being provided on the first face with a slit which is completely transparent to X-rays and which is configured to generate an X-ray flow when the collimator is exposed to an X-ray source, the slit extending longitudinally in the main plane of the support along an axis located at a non-zero distance (d) from the axis of rotation (?), the slit extending through the entire thickness of the support.

Abstract: Silicone material obtained by a reaction between:—at least one organopolysiloxane (A) that has a molar mass of less than 70,000 g/mol, preferably less than 50,000 g/mol, and contains siloxyl units I.1 and I.2; and—at least one organic compound (B) carrying at least two carboxylic acid groups and having no unsaturation. Y a ? Z b 1 ? SiO 4 - ( a + b ) 2 ( I ? .1 ) Z c 2 ? SiO 4 - c 2 ( I ? .