Patents Assigned to A. Nattermann & Cie GmbH
  • Foliage fertilizers
    Patent number: 4576626
    Abstract: New foliage fertilizers containing one or more macronutrients and/or one or more micronutrients as well as 10 to 50% by weight (referred to total nutrients) of one or more phospholipids.
    Type: Grant
    Filed: April 15, 1985
    Date of Patent: March 18, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Kurt H. Bauer, Miklos Ghyczy, Eugen Etschenberg, Heinrich Osthoff
  • Pharmaceutical amitriptylin oxide preparation and process for its manufacture
    Patent number: 4567202
    Abstract: Stable pharmaceutical preparations comprising amitriptylin oxide dihydrate as an active substance and an organic acid from the group of hydroxy carboxylic acids, ketocarboxylic acids or amino acids as a stabilizer besides conventional pharmaceutical auxiliaries and carrier substances.
    Type: Grant
    Filed: November 3, 1983
    Date of Patent: January 28, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Manfred Durr, Benedikt Gajdos, Klaus-Dieter Gneuss, Ekkehard Harhausen, Jurgen Seidel
  • Substituted aminoalkanol phospholipids
    Patent number: 4565659
    Abstract: The invention concerns new substituted aminoalkanol phospholipids of the general Formula I ##STR1## and methods for the treatment of humans suffering from high blood-pressure (hypertension), from inflammatory illnesses, from tumors and/or atherosclerosis by administering medicaments containing such a compound as well as methods for plant protections.
    Type: Grant
    Filed: October 18, 1983
    Date of Patent: January 21, 1986
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Harald Borbe, Gerrit Prop, Ferdinand Wirtz-Peitz, Ille-Stephanie Doppelfeld, Michael J. Parnham
  • O-Alkyl-O-carbamoylglycerophosphocholines and the use for treating hypertension
    Patent number: 4552869
    Abstract: The present invention relates to new O-alkyl-O-carbamoylglycerophosphocholines of the general formulae I or II ##STR1## and processes for treating human beings suffering from diseases caused by hypertension by administering one or several of the above compounds.
    Type: Grant
    Filed: June 15, 1984
    Date of Patent: November 12, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Hans Betzing, Gerrit Prop, Ottfried Zierenberg
  • Method of treating high blood pressure using 6-[4-(1-imidazolyl)-phenyl]-5-methyl-3-oxo-tetrahydropyridazines
    Patent number: 4551455
    Abstract: The present invention relates to new 6-[Imidazolyl-phenyl]-5-methyl-3-oxo-tetrahydropyridazines of the general formula I ##STR1## as well as their acid addition salts, methods for their use, and pharmaceutical preparations containing them.
    Type: Grant
    Filed: March 25, 1983
    Date of Patent: November 5, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Gerd Hilboll, Ille-Stephanie Doppelfeld, Gerrit Prop
  • Benzisoselenazolones and a process for the treatment of inflammatory diseases
    Patent number: 4550168
    Abstract: The invention relates to new benzisoselenazolones of the general formula I ##STR1## and a process for the treatment of humans suffering from inflammatory diseases of the rheumatic type.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: October 29, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Sigurd Leyck, Eugen Etschenberg
  • Process for producing (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene
    Patent number: 4518783
    Abstract: This invention relates to processes for producing the (-)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for lowering the blood pressure in human beings suffering from increased blood pressure, using these compounds.
    Type: Grant
    Filed: May 27, 1983
    Date of Patent: May 21, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Gerrit Prop, Ille-Stephanie Doppelfeld
  • 6-{4-(.omega.-(1-imidazolyl)-alkyl-phenyl}-3-oxo-2,3,4,5-tetrahydro- pyridazines and acid addition salts thereof, and a process for the treatment of inflammatory, atherosclerotic and thromboembolic illnesses in humans
    Patent number: 4507298
    Abstract: The invention relates to new 6-{4-(.omega.-(1-imidazolyl)-alkyl)-phenyl}-3-oxo-2,3,4,5-tetrahydro-pyrid azines having the general formula I ##STR1## and acid addition salts thereof, and to a process for the treatment of inflammatory, atherosclerotic and thromboembolic diseases especially in humans.
    Type: Grant
    Filed: July 12, 1982
    Date of Patent: March 26, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Gerd Hilboll, Hugo Friehe, Josef P. Lohr
  • Process for the spray application of plant protective spray mixtures and packing units for concentrates
    Patent number: 4506831
    Abstract: Process for the application of plant protectant spray mixtures in which the phospholipid concentrates are applied to open ground, phospholipids being discharged along with commercially available, diluted effective ingredient concentrates and the spray mixtures being formed before discharge from the active ingredient concentrate, water, and the phospholipid concentrate. This process employs packing units which contain the active ingredient concentrate and the appropriate quantity of phospholipid concentrate in separate compartments.
    Type: Grant
    Filed: June 28, 1983
    Date of Patent: March 26, 1985
    Assignee: Nattermann & Cie GmbH
    Inventors: Miklos Ghyczy, Paul-Robert Imberge, Armin Wendel
  • Optically active dipeptides and the use thereof as tissue dissolving and histolytic agent in human beings
    Patent number: 4505854
    Abstract: The invention relates to the new optically active dipeptide D-2-phenylglycyl-D-2-phenylglycine and its pharmacologically acceptable salts or acid addition salts and the use thereof as tissue dissolving and histolytic agent.
    Type: Grant
    Filed: January 5, 1984
    Date of Patent: March 19, 1985
    Assignee: Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Eugen Etschenberg, Hugo Friehe, Wolfgang Scheef, Johannes Winkelmann
  • 6-{5-[.omega.-(1-Imidazolyl)-alkyl] -thien-2-yl}-3-oxo-2,3,4,5-tetrahydro-pyridazines and acid addition salts thereof and a process for the treatment of inflammatory atherosclerotic and thrombo-embolic, illnesses in humans
    Patent number: 4504479
    Abstract: The invention relates to new 6-{5-[.omega.-(1-imidazolyl)-alkyl]-thien-2-yl}-3-oxo-2,3,4,5-tetrahydro-p yridazines having the general formula I ##STR1## and acid addition salts thereof and to a process for the treatment of inflammatory, atherosclerotic and thrombo-embolic diseases especially in humans.
    Type: Grant
    Filed: July 12, 1982
    Date of Patent: March 12, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans-Heiner Lautenschlager, Gerd Hilboll, Hugo Friehe, Josef P. Lohr
  • Process for filling pharmaceutical products containing phospholipides and highly viscous at room temperature, into hard capsules
    Patent number: 4497157
    Abstract: The present invention is related to a process for filling pharmaceutical products which contain 10 to 98% by weight of a phospholipide and which are highly viscous at room temperature, into hard capsules by admixing to such products a solvent or mixture of solvents in particular amounts, said solvent or solvent mixture having particular evaporation properties, and ejecting the resulting product from a usual filler nozzle under particular conditions, and closing the filled capsule with its cap.
    Type: Grant
    Filed: June 2, 1981
    Date of Patent: February 5, 1985
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Manfred Durr, Hans-Ulrich Fribolin
  • Method for the preparation of phosphatidyl choline of low oil content
    Patent number: 4496486
    Abstract: An improved method is provided for the preparation of phosphatidyl choline having a low oil content. An alcohol and oil-containing phosphatide solution is admixed with an amount of water sufficient to cause oil present therein to separate from the solution. The oil is removed from the solution and a phosphatidyl choline fraction recovered which is substantially oil-free.
    Type: Grant
    Filed: March 30, 1983
    Date of Patent: January 29, 1985
    Assignee: A. Nattermann & Cie. GmbH
    Inventor: Bernd-Rainer Gunther
  • Phospholipid solutions
    Patent number: 4482474
    Abstract: Aqueous phospholipid solutions and their preparations, consisting of phospholipids and a solution promoter of the general formula CH.sub.3 (CH.sub.2).sub.n CONHCH.sub.2 CH.sub.2 OH, in which n is 3, 4 or 5.
    Type: Grant
    Filed: May 11, 1983
    Date of Patent: November 13, 1984
    Assignee: A. Nattermann & Cie GMBH
    Inventors: Juergen Biedermann, Hans Betzing
  • Indol acetic acid derivatives and anti-inflamatory and related uses thereof
    Patent number: 4464379
    Abstract: The present invention is related to new indol acetic acid derivatives having the general formula ##STR1## the salts thereof, processes for producing the same and pharmaceutical preparations comprising the same as well as their use as drugs having antithrombotic, antiarteriosclerotic and antiphlogistic activity.
    Type: Grant
    Filed: June 1, 1981
    Date of Patent: August 7, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Hans Betzing, Sigurd Leyck
  • Triphenylimidazolyloxyalkanoic acids and their derivatives and a process for the treatment of thromboembolic, inflammatory and/or atheriosclerotic diseases
    Patent number: 4460598
    Abstract: The invention relates to new triphenylimidazolyloxyalkanoic acids of the general formula I ##STR1## and a process for the treatment of thromboembolic, inflammatory and/or atherosclerotic diseases in humans by using the same.
    Type: Grant
    Filed: July 25, 1983
    Date of Patent: July 17, 1984
    Assignee: A. Nattermann & Cie GMBH
    Inventors: Hans-Heiner Lautenschlager, Andre Welter, Gerd Hilboll, Johannes Winkelmann, Gerrit Prop, Axel Brekle, Ottfried Zierenberg
  • Cycloalkyl derivatives of benzisoselenazolones
    Patent number: 4454068
    Abstract: The invention relates to new benzisoselenazolones of the general formula I ##STR1## and to the use thereof in the treatment of inflammatory diseases in humans.
    Type: Grant
    Filed: July 12, 1983
    Date of Patent: June 12, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Andre Welter, Sigurd Leyck, Eugen Etschenberg
  • Process for the separation of oils and/or phosphatidylethanolamine from alcohol soluble phosphatidylcholine products containing the same
    Patent number: 4452743
    Abstract: The present invention is related to a new process for the separation of oil and/or phosphatidylethanolamine from alcohol soluble phosphatidylcholine products containing the same thus producing, by chromatography on silicic acid gel in a lower alkanol containing 1 to 4 carbon atoms as solvent and/or eluant, a phosphatidylcholine product containing oils and/or phosphatidylethanolamine in a definite diminished amount.
    Type: Grant
    Filed: December 1, 1981
    Date of Patent: June 5, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventor: Bernd-Rainer Gunther
  • Process for the separation of acylated phospholipids from phosphatidylcholine products containing the same
    Patent number: 4443378
    Abstract: The present invention is related to a new process for the separation of acylated phospholipids, in particular of acylated phosphatidylethanolamine and possibly oils from phosphatidylcholine products containing the same, by chromatography on silicic acid gel in a lower alkanol containing 1 to 4 carbon atoms as solvent and/or eluant yielding into highly purified phoshatidylcholine.
    Type: Grant
    Filed: December 1, 1981
    Date of Patent: April 17, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventor: Bernd-Rainer Gunther
  • (+)-2-[1-(2,6-Dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine
    Patent number: 4443464
    Abstract: This invention relates to (+)-2-[1-(2,6-dichlorophenoxy)-ethyl]-1,3-diazacyclopent-2-ene and to pharmaceutically acceptable acid addition salts thereof and the method for the treatment of human beings suffering from nervous disarrangements, in particular migraine, using these compounds.
    Type: Grant
    Filed: April 13, 1982
    Date of Patent: April 17, 1984
    Assignee: A. Nattermann & Cie GmbH
    Inventors: Jurgen Biedermann, Gerrit Prop, Ille-Stephanie Doppelfeld