Abstract: The multi-point probe comprises a supporting body defining a first surface, a first multitude of conductive probe arms each of the probe arms defining a proximal end and a distal end being positioned in co-planar relationship with the first surface of the supporting body. The probe arms are connected to the supporting body at the proximal ends thereof and have the distal ends freely extending from the supporting body, giving individually flexible motion to the first multitude of probe arms. The probe arms originate from a process of producing the probe arms on a wafer body in facial contact with the wafer body and removal of a part of the wafer body providing the supporting body and providing the probe arms freely extending therefrom. The multi-point probe further comprises a third multitude of tip elements extending from the distal end of the first multitude of probe arms. The tip elements originate from a process of metallization of electron beam depositions on the probe arms at the distal ends thereof.

Abstract: The present invention relates to compounds with structures resembling natural statins isolated from Penicillium sp.

Abstract: The present invention relates to a hearing aid with a compressor having a low and gain independent delay and low power consumption. The hearing aid comprises a multi-channel compressor for compensation of dynamic range loss and with a digital input for inputting a digital sound signal, and an output connected to an amplifier with a selectable gain as a function of frequency for compensation of frequency dependent hearing loss, and connected to an output for outputting the processed digital sound signal.

Abstract: Cultures of cells immunoreactive for glial fibrillary acidic protein (GFAP), as well as for the intermediate filament marker nestin were grown in a medium including epidermal growth factor (EGF) and serum. The cultured cells had the morphology of astroglial cells. The cells can be proliferated in adherent or suspension cultures. Depending on the culture conditions, the cells can be induced to differentiate to neurons or glial cells. The cultures can be expanded over a large number of passages during several months, and survive, express an astroglial phenotype and integrate well after transplantation into both neonatal and adult rat forebrain.

Abstract: For determining a subjective property such as loudness of a binaural sound signal left and right sound pressures in the left and right ears of a human being, resulting from the binaural sound signal, are determined. The left and right ear and right sound pressures are frequency analyzed to obtain left and right frequency spectra. In each frequency band, the diotic (common) sound pressure in the left and right ears is determined, which would result from a plane wave frontal incidence on the human being, and that would produce the same perceived loudness as the frequency bandwidth limited left and right sound pressures. In each frequency band the inverse frontal headrelated transfer functions are used to determine the free-field sound pressure that would produce the same perceived loudness as the diotic sound pressure. The loudness is determined as the loudness of the totality of frequency bandwidth limited free field sound pressures, preferably using the international standard ISO 532.

Abstract: A method for killing or inactivating spores, by contacting the spores with a haloperoxidase, a source of hydrogen peroxide and a source of iodide ions. The spores may additionally be contaced with a haloperoxidase enhancing agent.

Abstract: The present invention relates to the field of therapeutic use of proteins, genes and cells. More specifically the invention relates to therapy based on the biological function of a secreted therapeutic protein. NsG33, in particular for the treatment of disorders of the nervous system. NsG33 is a nerve survival and growth factor with antiapoptotic effects on a cell line with neuronal potential and with neuroprotective and/or neurogenesis effects on a neural precursor cell line and on primary striatal cultures. The invention also relates to novel bioactive NsG33 polypeptide fragments and the corresponding encoding DNA sequences.

Abstract: Use of escitalopram (the S-(+)-enantiomer of citalopram) or a pharmaceutically acceptable salt thereof for the preparation of a medicament useful in the treatment of neurotic disorders is provided, including anxiety states, in particular generalized anxiety disorder and social anxiety disorder, post traumatic stress disorder, obsessive compulsive disorder and panic attacks.

Abstract: A process for the preparation of a particulate material by a controlled agglomeration method, i.e. a method that enables a controlled growth in particle size. The method is especially suitable for use in the preparation of pharmaceutical compositions containing a therapeutically and/or prophylactically active substance which has a relatively low aqueous solubility and/or which is subject to chemical decomposition. The process comprising i) spraying a first composition comprising a carrier, which has a melting point of about 5° C. or more which is present in the first composition in liquid form, on a second composition comprising a material in solid form, the second composition having a temperature of at the most a temperature corresponding to the melting point of the carrier and/or the carrier composition and ii) mixing or others means of mechanical working the second composition onto which the first composition is sprayed to obtain the particulate material.

Abstract: A liquid crystal display has a backlight unit for providing substantially unpolarized illumination, a rear polarizer proximate the backlight unit for receiving the incident substantially unpolarized illumination and transmitting substantially polarized illumination. A liquid crystal spatial light modulator forms a modulated beam by selective, pixel-wise modulation of the polarization of the substantially polarized illumination. A color filter array transmits selected wavelengths of the modulated beam from the LC spatial light modulator. A front polarizer has a transmission axis for transmitting the portion of the modulated beam having polarization in alignment with the transmission axis. A reflective polarizing element is disposed between the liquid crystal spatial light modulator and the front polarizer for reflecting a portion of dark state light back toward the backlight unit.

Abstract: Process for the removal of coloured compounds in a hydrocarbon feedstock comprising the steps of hydrotreating the feedstock in presence of a first hydrotreating catalyst under conditions being effective in hydrogenation of hydrogenable compounds being present in the feedstock and hydrotreating an effluent from the first hydrotreating step in a second catalytic hydrotreating step being carried out in a second hydrotreating reactor at hydrotreating conditions, wherein the effluent from the first hydrotreating step is separated into a gas phase and a mixed gas and liquid phase prior to the second hydrotreating step, and the mixed phase is hydrotreated in the second hydrotreating step without further addition of hydrogen.

Abstract: Recombinant poxvirus are disclosed comprising in the viral genome at least two expression cassettes, each comprising a cowpox ATI promoter according to SEQ ID NO:1, a polynucleotide sequence in which not more than 6 nucleotides are substituted, deleted, and/or inserted into SEQ ID NO:1 and still active as an ATI promoter, or a polynucleotide comprising at least 10 nucleotides including nucleotides 22 to 29 of SEQ ID NO: 1 and still active as an ATI promoter and a coding sequence, wherein the expression of the coding sequence is regulated by said promoter or said polynucleotides. The recombinant poxviruses are useful as pharmaceutically active ingredients in the preparation of vaccines.

Abstract: This invention relates to novel diazabicyclic biaryl derivatives, which are found to be cholinergic ligands at the nicotinic acetylcholine receptors and modulators of the monoamine receptors and transporters. Due to their pharmacological profile the compounds of the invention may be useful for the treatment of diseases or disorders as diverse as those related to the cholinergic system of the central nervous system (CNS), the peripheral nervous system (PNS), diseases or disorders related to smooth muscle contraction, endocrine diseases or disorders, diseases or disorders related to neuro-degeneration, diseases or disorders related to inflammation, pain, and withdrawal symptoms caused by the termination of abuse of chemical substances.

Abstract: An arrangement for conveying product material to a weighing system includes an infeed for product material to be weighed and at least one dosing mechanism for controlled conveyor of product material portions from the infeed to a weighing system. The dosing mechanism includes a motor-driven transport screw formed as a helically-shaped rod positioned in an open trough for conveying the product material from the infeed to the weighing system, and a control unit for controlling the motor in order to deliver a desired portion of product material to the weighing system. This arrangement provides a gentle, well-defined conveyance of product materials that are not suited for vibrational conveyance or conveyance by a screw conveyor in a tubular housing.

Abstract: The present invention relates to providing antibodies against human heparin-binding protein (hHBP) or against a homologue of hHBP, such as porcine heparin binding protein (pHBP) or human neutrophil elastase (hNEL), and using said antibodies for the manufacture of a medicament for treatment of Gram positive and/or Gram negative infections, sepsis, disseminated intravascular coagulation, modulation of inflammatory response, and/or prevention of cell apoptosis. Antibodies of the invention are capable of modulating at least one inflammatory response associated with hHBP, in particular, the invention relates to monoclonal antibody F19A5B1, capable of stimulating said at least one inflammatory response, and monoclonal antibody F19A5B4, capable of inhibiting said at least one inflammatory response.

Abstract: A new miniature rose plant that has abundant, yellow orange flowers and attractive foliage. The variety successfully propagates from softwood cuttings and is suitable for year-round production in commercial glasshouses. This new and distinct variety has shown to be uniform and stable in the resulting generations from asexual propagation.