Abstract: In a roller adjustment apparatus for an extrusion mill, comprising a cylindrical die (2) with radially extending extrusion channels and a number of rollers (1) within the die, rotatable about their axes and co-operating with the die to press material to be treated through the extrusion channels in the die wall, the adjustment apparatus comprises eccentrically journalled bearing shafts (3) for mounting the rollers (1), said eccentrically journalling of the shafts (3) providing a radial adjustment of the position of the rollers (1) relative to the die (2), the rotation of the eccentrically journalled shafts (3) is provided by means of extension arms (6) fixedly mounted on the ends of the eccentrically journalled shafts (3), and said extension arms (6) being connected to an axially movable connection element (8) by means of articulated connected linkage rods (7), and said connection element (8) being connected to a rod (9) provided with its axis in the axis of the die (2) and extending to a position outside the

Abstract: The present invention relates to methods for producing a polypeptide of interest by (a) cultivating a mutant of a parent Aspergillus cell, wherein (i) the mutant comprises a first nucleic acid sequence encoding the polypeptide and a second nucleic acid sequence comprising a modification of at least one of the genes responsible for the biosynthesis or secretion of at least one toxin, and (ii) the mutant produces less of the toxin than the parent Aspergillus cell when cultured under the same conditions; and (b) isolating the polypeptide from the culture medium. Also, mutants of Aspergillus cells are provided, as well as methods for obtaining the mutant cells.

Abstract: An injection device for injection of set doses of medicine from a cartridge, in which syringe a dose is set by screwing a nut up along a threaded piston rod, whereby a dose setting drum, which carries on its cylindrical surface along a helix a scale of which a number corresponding to the set dose is shown in a window in the housing of the syringe, and an injection button, which is elevated over the end of the syringe, are moved axially a distance which is larger than the axial movement of the nut. A gear wheel gear transmission is established between the nut and the injection button.

Abstract: The inventor has found that enzymatic treatment of crustaceans with lipolytic enzymes promotes the extraction of coloured pigment. Accordingly, the invention relates to a method for recovering coloured pigment, e.g. astaxanthin, and/or chitin or chitosan and/or lysolecithins from crustaceans. Lipolytic enzyme(s) may e.g. be lipase or phospholipase. The lipolytic enzyme treated crustacean material may be subjected to additional process steps, including treatment with non-lipolytic enzymes such as e.g. protease. The process of the invention provides several suitable products and several uses of such products. Furthermore, the invention also relates to the cosmetic and consumable products (feed and food (including beverages) products and additives produced therefrom.

Abstract: A flow control valve includes a valve body defining fluid inlet and outlet sections interconnected by a connecting port. A valve unit is disposed in the valve body and is operably connected to an actuator to be moved thereby for opening and closing the connecting port. The valve unit includes a valve element which has a bleed passage extending therethrough for communicating the fluid inlet and outlet sections with one another. A bleed piston is operably connected to the actuator and is movable thereby relative to the valve element for opening the bleed passage when the valve unit is in a port-closing position. The valve unit also includes a pressure balancing passage which communicates front and rear ends of the valve element with one another and tending to aid in statically and dynamically balancing the fluid pressures acting on the valve element.

Abstract: Process and system for the production of synthesis gas from a hydrocarbon feed stock comprising the steps of endothermic and/or adiabatic catalytic steam reforming and autothermal steam reforming in series, wherein the steam reforming is carried out in one or more endothermic stages in series or in one or more adiabatic steam reforming stages in series with intermediate heating of feed stock gas leaving the adiabatic reforming stages and wherein carbon monoxide containing gas characterised by having a molar ratio of hydrogen to carbon of less than 4.5 is added prior to at least one of the endothermic or adiabatic steam reforming stages and/or prior to the autothermal steam reforming step.

Abstract: The present invention relates to a method of logging or recording input signal data of a hearing prosthesis in combination with values of one or several variables associated with the hearing prosthesis. The hearing prosthesis variable(s) may comprise logic states of a single or several user-controllable actuator(s) mounted on the prosthesis and/or values of algorithm parameters of a predetermined digital signal processing algorithm executed in the prosthesis. Hereby, error tracking and performance optimisation are facilitated since anomalous or sub-optimal operating conditions of signal processing algorithms and/or user interface control handling or other undesired events may be detected. By recording both the hearing prosthesis variable or variables and the input signal data, it is e.g. possible to identify and track correlations between one or several predetermined signal events in the input signal data and effects to the operation of the hearing prosthesis derived there from.

Abstract: The invention relates to a method of producing ethanol by fermentation, said method comprising a secondary liquefaction step in the presence of a thermostable acid alpha-amylase or a thermostable maltogenic acid alpha-amylase.

Abstract: A monoacyl semicarbazide of the general formula (I): (I), or a pharmaceutically acceptable salt or ester thereof, is capable of selectively inhibiting dipeptidyl-peptidase I (DPP-I), also known as cathepsin C. A compound of the invention is useful as an active substance for the treatment of inflammation, type 2 diabetes, asthma, severe influenza, respiratory syncytial virus infection, CD8 T cell inhibition, inflammsatory bowel diseases, psoriasis, atopic dermatitis, Papillon Lefevre syndrome, Haim Munik syndrome, gum disease, periodontitis, rheumatoid arthritis, Huntington's disease, Chaga's disease, Alzheimer's disease, sepsis or for application in target cell apoptosis.

Abstract: A pseudo-sequence method for comparing 7TM receptors with respect to the physicochemical properties of their binding sites, the method comprising the steps of: (i) optionally, aligning part of or all of the amino acid sequence of the first 7TM receptor with part of or all or the amino acid sequence of the one or more further 7TM receptors, (ii) selecting, in a sequential or non-sequential order, at the most 12 amino acid residues per helix and/or extracellular loops, which are involved in one or more binding sites of each 7TM receptor.

Abstract: Stable, soluble insulin formulations having both a fast and a long action.

Abstract: Some embodiments of a medical infusion pump system include a pump device and a removable controller device. When the pump device and the removable controller device are removably attached to one another, the components may provide a portable infusion pump unit to dispense medicine to a user. In particular embodiments, the removable controller device includes a user interface to readily provide information, for example, about the operation of the pump.

Abstract: A front projection screen assembly comprising, a rectangular sheet of a flexible screen material and a roller on which said flexible screen material may be wound and unwound, said flexible screen material defining a first plane in the unwound condition. The front projection screen assembly comprises top, bottom, left-hand and right-hand side frame members, framing said rectangular sheet of flexible screen material along respective top, bottom, left-hand and right-hand sides thereof. At least said side frame members comprise shape memory members.

Abstract: The invention concerns an electronic mail management (EMM) system for handling electronic mail in a multiple user environment, in which the user's incoming electronic mail is sent and received, said system includes a mail distribution network including a server through which, electronic mail items of the users are exchanged, said system comprising: detecting means for monitoring the flow of in- and outbound electronic mails for a specified set of users, and intercepting the in- and outbound emails; journalizing means for creating a notification record of a set of e-mail information data (metadata) for each intercepted electronic mail; an e-mail manager database (EMM DB) for storing at least said notification record and each electronic mail; and means for establishing a journal of e-mails by defining a search request query and submitting said search request to a search engine for selecting a user defined series of information data from the notification records in the EMM database.

Abstract: A pharmaceutical composition for oral administration comprising PTH, wherein the in vitro release of PTH-when tested in a dissolution test of pharmacopoeia standard-is delayed with at least 2 hours and once the release starts, at least 90% w/w such as, e.g., at least 95% or at least 99% of all PTH contained in the composition is released within at the most 2 hours. The composition may also comprises a calcium containing compound and/or a vitamin, D. In particular, PTH is administered in combination with a calcium-containing compound for the treatment or prevention of bone-related diseases, so that I) an effective amount of a calcium-containing compound is administered to lower the plasma level of endogenous PTH, and II) an effective amount of PTH is administered to obtain a peak concentration of Pm once the endogeneous PTH level is lowered. This present a potential therapeutic or prophylactic regimen for bone-related disorders including osteoporosis.

Abstract: An optical touch pad that includes a multilayer waveguide optically coupled to at least one electromagnetic radiation detector. Based on electromagnetic radiation directed from an object to the detector by the multilayer waveguide, information related to an object proximate to (e.g., hovering above) and/or in contact with the optical touch pad may be determined. For example, the information related to the object may include position information, object-type information, and/or other information related to the object.

Abstract: The invention relates to an optical waveguide laser comprising a) an active region formed over a length of the optical waveguide, comprising an excitable material emitting light in response to stimulation by pump light thereby defining an optical gain profile and the excitable material comprises Tm; b) a frequency discriminated feedback element adapted to select a single longitudinal lasing mode by coordination with the frequency response of the optical gain of the excitable material; and c) a polarisation asymmetry element adapted for selecting a single polarisation mode of a given longitudinal mode by selectively suppressing propagation of the other polarisation mode of said longitudinal mode. The object of the present invention is to provide relatively simple, compact and economic lasers for single-frequency operation in the wavelength range of 1.7 um to 2.2 um; in particular for a number of applications, including spectroscopy and for eye-safe optical sources in sensing and in LIDAR, etc.

Abstract: A passive alignment technique is disclosed to facilitate accurate positioning of components of an optical assembly. In one aspect, a method includes directing light onto components of an optical assembly in which a first component includes a first pattern of marks with a first frequency and a second component includes a second pattern of marks with a second different frequency. An optical signal corresponding to the superposition of the first and second patterns is detected. Based on the detected optical signal, a determination may be made as to whether the first and second components are properly positioned with respect to one another.

Abstract: A pumping system for moving water of a swimming pool includes a water pump and a variable speed motor. The pumping system further includes means for determining a first motor speed of the motor, means for determining first and second performance values of the pumping system, and means for comparing the first and second performance values. The pumping system further includes means for determining an adjustment value based upon the comparison, means for determining a second motor speed based upon the adjustment value, and means for controlling the motor in response to the second motor speed. In one example, the pumping system includes means for determining a value indicative of a flow rate of water moved by the pump. In addition or alternatively, the pumping system includes a filter arrangement. A method of controlling the pumping system for moving the water of the swimming pool is also disclosed.