Abstract: Process for microfiltration at elevated temperature.

Abstract: The present invention relates to insulin derivatives in which a lipophilic group having from 12 to 40 carbon atoms is attached to the ?-amino group of the N-terminal amino acid in the B-chain or to the carboxy group of the C-terminal amino acid in the B-chain have a protracted profile of action.

Abstract: An apparatus for removal bones from a fish fillet is presented. A conveyor is provided for conveying the fish fillet and supporting means is arranged on said conveyor for supporting the fish fillet as it is being conveyed by means of imposing the fish fillet on it so that the bones to be removed are exposed. A second supporting means is arranged sidewise to said first supporting means for maintaining the fish fillet in a fixed position as the exposed bones are removed with a bone removal unit, which is arranged above the conveying means.

Abstract: The invention relates to a variant of a parent Fungamyl-like fungal alpha-amylase, which exhibits improved thermal stability at acidic pH suitable for, e.g., starch processes.

Abstract: A system for electronic registration of air travel logbooks, wherein data input is performed by a person in two steps. The first step includes the input of data into a terminal and the correction of any errors. The second step includes the permainent storage and processing of the data in a computer. The permanent storing prevents subsequent changing of the input data, whereby the second step is performed only with access to the computer obtained by verification of conformity between the identity of the person and a password. Access to the computer is obtained by the person for the output of data regarding the person by using the password. An authority obtains access to data in the computer regarding a specific person by using a first code, and to data regarding a specific aircraft's flights by using a second code.

Abstract: Variants of Glycoside Hydrolase family 53 galactanases, e.g. variants of the galactanases from strains of Yersinia, Aspergillus, Humicola, Meripilus, Myceliophthora, Thermomyces, Bacillus, Bifidobacterium, Cellvibrio, Clostridium, Pseudomonas, Thermotoga, or Xanthomonas.

Abstract: A human embryonal stem cell, neural stem cell, neural precursor cell, neural cell or dopaminergic neuron is genetically modified to overexpress at least one of certain genes identified as regulated in the developing human ventral mesencephalon, and more particularly, up-regulated in the ventral tegmentum. The genes are associated with dopaminergic differentiation.

Abstract: The present invention is related to single-chain insulin having insulin activity comprising a B- and an A-chain or a modified B- and A-chain connected by a connecting peptide of from 6-11 amino acids. The single-chain insulins will have biological insulin activity and an IGF-1 receptor affinity similar to or lower than that of human insulin and a high physical stability. The single-chain insulin may contain at least one basic amino acid residues in the connecting peptide. The single-chain insulins may also be acylated in one or more Lys residues.

Abstract: A progeny cell derived from a parent cell, wherein the progeny cell comprises at least one gene encoding MrgA protein or a functional homologue thereof and/or a DNA segment operably linked with the encoding gene, wherein said gene and/or DNA segment is manipulated with respect to the parent cell; the progeny cell comprises two or more copies of a gene encoding MrgA protein or a functional homologue thereof; or the progeny cell is mutated with respect to the parent cell; whereby the progeny cell produces greater amounts of MrgA protein or a functional homologue thereof than the parent cell.

Abstract: The invention relates to a micro light modulator arrangement (10) comprising at least one light transmission path (23) and at least one controllable shutter (11, 16) arranged for modulation of light transmitted via said at least one light transmission path (23), said at least a part of said light transmission path comprising a translucent solid material, and said at least a part of said light transmission path being an integral part of a substrate to which said at least one controllable shutter (11, 16) is anchored.

Abstract: The present invention relates to enzyme preparations consisting essentially of an enzyme which has cellulytic activity and comprises a first amino acid sequence having the following sequence (SEQ ID NO: 79) Thr Arg Xaa Xaa Asp Cys Cys Xaa Xaa Xaa Cys Xaa Trp Xaa 1 2 3 4 5 6 7 8 9 10 11 12 13 14 and a second amino acid sequence having the following sequence Trp Cys Cys Xaa Cys (SEQ ID NO: 80) 1 2 3 4 5 wherein, at position 3 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 4 of the first sequence, the amino acid is Trp, Tyr or Phe; at position 8 of the first sequence, the amino acid is Arg, Lys or His; at positions 9, 10, 12 and 14, respectively, of the first sequence, and at position 4 of the second sequence, the amino acid is any of the 20 naturally occurring amino acid residues with the provisos that, in the first amino acid sequence, (i) when the amino residue at position 12 is Ser, then the amino acid residue at position

Abstract: The invention relates to a method of distributing a liquid in the fluid bed of an up-flow or a down-flow fluid bed reactor. The invention provides efficient distribution and plug flow like fluid flow through the fluid bed where turbulence and/or back-mixing of the fluid are minimized. In accordance with the invention a fluid bed system for use in treating a fluid by contacting the fluid with a solid phase media is provided and the system includes a reactor chamber adapted to contain the solid phase media and at least one fluid distribution means adapted to distribute and/or deliver the fluid to be treated among the particles of the medium.

Abstract: The present invention relates to novel derivatives of exendin-4 or exendin-4 fragments, wherein the derivatives have a lipophilic substituent attached, optionally via a spacer, to an amino acid residue, which is not the N-terminal or C-terminal amino acid residue of the derivative.

Abstract: The invention relates to a sensor for the in vivo measurement of an analyte, comprising a plurality of particles of suitable size such that when implanted in the body of a mammal the particles can be ingested by macrophages and transported away from the site of implantation, each particle containing the components of an assay having a readout which is an optical signal detectable transdermally by external optical means, and either each particles being contained within a biodegradable material preventing ingestion by the macrophages, or each particle being non-biodegradable. The invention relates to a process for the detection of an analyte using such a sensor, comprising implantation of the sensor into the skin of a mammal, transdermal detection of analyte using external optical means, degradation of the biodegradable material, ingestion of the particles by macrophages, and removal of the particles from the site of implantation by macrophages.

Abstract: The properties of a fungal lipolytic enzyme can be altered by substituting amino acid residues corresponding to certain specified amino acid residues in the T. lanuginosus lipase. The altered property may be, e.g., an increased thermostability, an altered pH dependence, or an altered substrate specificity.

Abstract: The present invention relates to a receiver module being adapted to be positioned in an ear canal, the receiver module comprising a receiver having a receiver housing, said receiver being adapted to receive a time dependent electrical signal, said receiver further being adapted to generate outgoing acoustic waves via an output port in the receiver housing in response to the received time dependent electrical signal, and expansible means surrounding at least part of the receiver housing, said expansible means having an opening aligned with the output port of the receiver housing so as to allow the generated outgoing acoustic waves to penetrate away from the receiver module and into the ear canal.

Abstract: An infusion pump system is described that increases patient comfort and convenience. The infusion pump system includes an infusion site interface that is releasably connected to an infusion pump body, and has no tubing associated between the infusion site interface and the pump body. The infusion pump body may include a carrier frame that may be adhered to the skin of a user.

Abstract: The present invention relates to a method of treating the symptoms of premenstrual dysphoric disorder (PMDD) in a patient in need thereof by administering an effective amount of escitalopram or a pharmaceutically acceptable salt thereof.

Abstract: Certain novel sterol derivatives can be used for regulating the meiosis in oocytes and in male germ cells.