Abstract: A system for controlling a ship 1 comprises a ship 1 having: a ship control unit 204 configured to determine situation information of the ship 1; and a transmitter-receiver 12 connected to the ship control unit 204 and configured to transmit the situation information. A remote control centre 18 remote from the ship 1 comprises a transmitter-receiver 16 configured to receive situation information of the ship 1; and a remote control unit 202 configured to determine pilot-control information for maneuvering the ship 1 based on the situation information and configured to transmit the pilot-control information to the ship 1 via the transmitter-receiver 16 of the remote control centre 18. The ship control unit 204 or the remote control unit 202 is configured to determine a quality of a connection between the transmitter-receiver 12 of the ship 1 and the transmitter-receiver 16 of the remote control centre 18.

Abstract: A control system for controlling disconnection of riser system that extends between a vessel and a subsea location that comprises a wellbore, the riser system configured to receive a string in use, the control system being configured to disconnect the riser system according to a sequence of operations, the sequence of operations comprising disconnecting the riser system prior to or simultaneous with cutting the string and sealing the well bore.

Abstract: A plurality of sliding rails and a frame structure comprising a plurality of frame elements configured to be arranged at least partly circumferentially around a tower structure. Each frame element is slidably connected to at least one of the sliding rails, and the frame elements and the sliding rails are interconnected to form a scissor structure. An upwardly directed lifting force applied by a hoisting mechanism at connecting points at or near positions where the frame elements are connected to the sliding rails, in combination with gravity working on the frame structure, causes the frame elements to slide along the sliding rails, thereby causing the scissor structure to contract or expand to adjust a diameter of the frame structure to an outer diameter of the tower structure having the apparatus mounted thereon.

Abstract: The invention provides a lifting assembly comprising a support structure (4) arranged to support a load (2) suspended from the support structure, a guide line (501) arranged to extend from a first location, to a second location, a wheel assembly (601) with one or more wheels (621, 622, 623) arranged to engage, and roll along, the guide line (501), and a control line assembly (701) arranged to extend from the wheel assembly (601) to the load (2), wherein the lifting assembly comprises a retainer (801) arranged to connect, between the first and second locations, the guide line (501) to the support structure (4).

Abstract: A cochlear stimulation system for determining a Temporal Fine Structure (TFS) parameter of a spectral component of an incoming acoustic signal is provided. The system comprises a transducer receiving an incoming acoustic signal, and wherein a sampled audio signal of length N samples is provided based on the incoming acoustic signal, a storing unit including a plurality of window frequency differences and/or a plurality of window energy level differences. The system further comprises a signal processor for estimating the TFS parameter of the full frequency range of the sampled audio signal by locating a main spectrum sample of the plurality of spectrum samples having a maximum energy level within a range of frequencies centered around the main spectrum sample, and determining the TFS parameter based on the energy level difference for one or more of the spectrum samples of the group of spectrum samples and the window function.

Abstract: A sheet laminate for being used as a puncturable top web for a blister package, comprising: an aluminium base sheet layer; at least one tie layer comprising polyolefin; a welding layer comprising polyester or polypropylene; wherein the welding layer and the tie layer are coextrusion coated on the base sheet layer so that the at least one tie layer is disposed between the base sheet layer and the welding layer, whereby the welding layer is attached to the base sheet layer by the at least one tie layer. A blister package, wherein the sheet laminate is attached to a bottom web with product cavities. A method of manufacture of the sheet laminate and of the blister package, wherein the coextrusion coating step of the manufacture of the blister package is carried out simultaneously with extrusion lamination of a paper layer.

Abstract: The invention concerns a medical device provided with an outer part or shell and an inner functional part which inner functional part comprises a combination of units. The functional combination of units normally constitutes a device comprising a part being able to penetrate the skin of a patient i.e. a subcutaneous part such as a cannula, a sensor, an insertion needle or the like. Examples of such medical devices are inserter devices and infusion devices where each device comprises an outer part and an inner functional part according to claim 1.

Abstract: A method for fabricating a member in a resin-infusion-based casting process, in which at least one component forming the member is infused with a resin, including the steps: Providing a mold, the at least one component, the resin, at least one measurement device and at least one sensing device, wherein the sensing device has at least one property which changes measurably with temperature and/or when the sensing device comes into contact with the resin, attaching the at least one sensing device to an inner surface of the mold and/or to the component, arranging the component inside the mold, providing the resin to at least one inlet of the mold, and wirelessly measuring and evaluating the property of the sensing device with the measurement device for monitoring a temperature and/or a distribution of the resin in the mold and/or in the component, is provided.

Abstract: The present invention relates to a novel acylating agent, a method for its preparation, and a method of using it for acylating one or more amino groups of an amino acid, a peptide, or a protein. The novel acylating agent may be a compound which comprises a structural element —HN—(CH2)2-(O—((CH2)2)k-O—(CH2)n-CO—, wherein k is an integer in the range of 1-10, and n is an integer in the range of 1-2, being esterified at its —CO-end to the hydroxy group of 3,5-dichloro-2-hydroxy-benzenesulfonic acid (3,5-DC-2-HBSA). This novel acylating agent has an improved stability. Using this agent the acylation process is improved as regards robustness, as well as improving yield and overall production economy. The novel acylating agent is useful for acylating pharmaceutical peptides and proteins such as GLP-1, insulin, pYY, and amylin. The invention also relates to a number of novel GLP-1 precursor peptides and derivatives in which the two N-terminal amino acids have been deleted.

Abstract: There is provided a hearing aid with an antenna connected to a transmission and/or reception circuit for transmission and/or reception of the electromagnetic energy via the antenna. A coupling circuit, e.g. including a directional coupler, is configured to sense an electric return power from the antenna, and to generate a power signal based on the sensed electric return power. A controllable impedance circuit is connected to the antenna, so as to allow adjusting of impedance of the antenna in at least two different steps. A processor is configured to generate a tuning control signal to the controllable impedance circuit in response to the power signal. This allows control of the impedance of the antenna for minimizing impedance mismatch, and thus improve performance of the antenna by tuning the impedance to the operating conditions of the antenna, preferably in an automatic manner.

Abstract: An endoscope control system for performing a bending operation in a disposable insertion endoscope, the endoscope control system including a control wheel connected to a wire drum for connection to a steering wire of the endoscope, whereby rotation of the control wheel controls the bending operation, and a multi-disc brake including a stack of at least three brake discs, wherein activation of the multi-disc brake changes the multi-disc brake from a released state to a braking state, a brake torque generated by the multi-disc brake in the braking state braking rotation of the control wheel, the brake torque in the released state being at least partially released.

Abstract: A method for producing an ethanol solution includes obtaining, from a starting liquid, a liquid feed having less than by weight of constituents and having 3% to 25% by weight of ethanol, supplying the liquid feed to a feed stream inlet of a reverse osmosis separation system having a first pass, wherein (i) each pass has an reverse osmosis membrane filtration unit, each membrane filtration unit having an ethanol rejection percentage of between 50% to 99%, and (ii) each pass has the feed stream inlet for a feed stream, a permeate stream outlet for a permeate stream, and a retentate stream outlet for a retentate stream, operating the system to maintain pressure in one of the membrane filtration units in a range of 1,200 to 4,000 psi, and obtaining retentate that is enriched with ethanol, the retentate differs from the starting liquid by absence of the removed constituents.

Abstract: A water-dissolvable nicotine tablet is disclosed, the nicotine tablet comprising at least a first compressed module and a second compressed module, wherein the first compressed module is an FDT-module and comprises nicotine, alkaline pH regulating agent, and disintegrant, and, wherein the second compressed module is a lozenge-module and comprises acidic pH regulating agent. Also, a method of manufacturing a nicotine tablet is disclosed.

Abstract: A wind turbine (10) includes a tower (12), a nacelle (14) coupled to the tower (12) and housing one or more heat generating components (18, 20), a rotor (16) having a least one wind turbine blade (24), and a cooler (38) mounted to the nacelle (14) and configured to cool the one or more heat generating components (18, 20) in the nacelle (14) by circulating a working fluid. The cooler (38) includes a support frame (46) coupled to the nacelle (14) and a heat exchanger (48) coupled to the support frame (46) and configured to cool the working fluid. The heat exchanger (48) includes at least two cooling panels (58) in non-planar relation with each other. The at least two cooling panels (50) may also be pivotably coupled to each other. A method of assembling a cooler (38) is also disclosed.

Abstract: A disposable endoscope with a tip part including a vision sensor, an exterior housing having a front wall and a circumferential wall, an interior spacing of the exterior housing accommodating the vision sensor, and a camera window positioned at least partly in front of the vision sensor, the housing further comprising a nozzle provided at the distal end of the tip part and configured to flush an exterior surface of the window, wherein the front wall and the nozzle are integrally formed in one piece from one polymer material.

Abstract: Disclosed is a method at a binaural hearing device system, the system comprises a first hearing device for placement at, or in, a user’s first ear, the first hearing device comprising a first acoustic input transducer arrangement, a first signal processor, and a first wireless communication interface; and a second hearing device for placement at, or in, the user’s second ear, the second hearing device comprising a second acoustic input transducer arrangement, a second signal processor, and a second wireless communication interface. The method comprises, at a first signal processor, computing a first bilateral beamforming signal based on first and second monaural beamforming signals. Computing the first bilateral beamforming signal comprises an adaptive computation including a variable length FIR filter and a coefficient-based adaptation strategy.

Abstract: Disclosed is a method for reducing the usage amount of edible fat and oil in a bakery product, the method comprising mixing at least one maltose alpha-amylase and edible fat and oil into dough, and baking same to prepare a bakery product. The usage amount of the edible fat and oil in the dough can be reduced by at least 10 wt % compared with not using the enzyme treatment; and the enzyme may also include cellulase and/or phospholipase. The method does not reduce or substantially reduce the quality of the bakery product, and allows same to have a shelf life of at least 4 days. Also involved is baked fat and oil prepared from the above-mentioned enzyme and edible fat and oil.

Abstract: The invention relates to antisense oligonucleotides which alter the splicing of XBP1 pre-mRNA. The antisense oligonucleotides have applications in enhancing the level and/or quality of protein expression in cells and in mammalian protein expression systems, such as heterologous protein expression systems, such as enhancing antibody expression in CHO cells. The antisense oligonucleotides also have applications in therapy, such as for the treatment or prevention of proteopathological diseases.

Abstract: The present invention relates to protease variants having polyester degrading activity, polynucleotides encoding said variants, nucleic acid constructs and expression vectors comprising said polynucleotides, host cells expressing said variants, compositions comprising the variants, methods of producing the variants, and use of the variants.