Abstract: A self activating vent cap configured to be operably coupled to a needleless connector and automatically shifted relative to the needleless connector from the first, storage position to a second, activated position upon rotation of the vent cap relative to the needleless connector. The self activating vent cap including a threaded portion, an activation portion and a biasing mechanism, wherein shifting of the activation portion to the second, activated position is selectively precluded by the interference of at least one ridge of the threaded portion with a ledge of the activation portion.

Abstract: A topical ophthalmological composition includes a muscarinic receptor antagonist as an active pharmaceutical ingredient; and a semifluorinated alkane, as a liquid vehicle. The topical ophthalmological composition treats an ocular disease.

Abstract: A composition for use in the treatment of rosacea includes a multi-kinase inhibitor that inhibits both a Vascular Endothelial Growth Factor Receptor and a Fibroblast Growth Factor Receptor. A method for treating rosacea for a patient includes inhibiting a Vascular Endothelial Growth Factor Receptor of the patient; and inhibiting a Fibroblast Growth Factor Receptor of the patient.

Abstract: A method for treating a meibomian gland dysfunction of an affected eye includes administering to the affected eye of a subject in need of such treatment a steroidal-androgen-free composition containing a therapeutically effective amount of a cyclic polysaccharide. A steroidal-androgen-free composition includes a cyclic polysaccharide as an active pharmaceutical ingredient for treating a meibomian gland dysfunction of an affected eye.

Abstract: The invention relates to an energy store comprising an arrangement of battery cells (70, 80, 90) in an installation housing (2), wherein groups (I, II, III) of battery cells (70, 80, 90) follow one another in the direction of the longitudinal axis (10) of the installation housing (2). Within each group (I, II, III) of battery cells (70, 80, 90), a flow path (50, 51, 52) for cooling air is formed, which flow path connects a feed air opening (35, 36, 46) for a cooling air flow (5, 6) to a cooling air outlet (20, 21, 23). In order to achieve effective cooling, first feed air openings (35) and a first cooling air outlet (20) are associated with a first flow path (50) in a first group (I) of battery cells (70) and second feed air openings (36) and a second cooling air outlet (21) are associated with a second flow path (51) in a second group (II) of battery cells (80).

Abstract: An integrated control system (ICS) for a well drilling platform is provided, which well drilling platform has a plurality of control systems and devices. The ICS includes an ICS controller is in communication with a master control. The ICS controller includes a memory device coupled to a processor. Instructions executed by the processor cause the ICS controller to: communicate with each of the control systems to determine a status of each of the control systems; cause the master control display to display status information for at least one of the control systems; in response to an operator input perform a well drilling platform function, the function requiring a coordinated state between a first control system and at least a second control system, configure the first control system and the second control system into a coordinated state.

Abstract: A velocity sensor and housing therefore, the velocity sensor provides a measurement of the velocity in a sewer manhole or chamber. The velocity sensor includes an ultrasonic transducer that emits a signal to measure the liquid below and may use an additional transducer or it is used by itself to detect the signal reflected from the surface. A parabolic reflector is designed and arranged to direct the emitted ultrasonic signal from the transducer to the surface with a linear beam while minimizing the beam spread. The return echo may either be measured directly or with the same transducer that was used to transmit the ultrasonic signal.

Abstract: A well drilling system is provided that includes a choke manifold and a controller. The choke manifold includes at least one choke valve. The choke valve is actuable between fully open and closed choke positions. The choke valve has a Cv value for each choke position. The controller is in communication with the choke valve and a non-transitory memory storing instructions. The instructions relate Cv values to choke positions for the choke valve. The instructions when executed cause the controller to: a) determine a difference in pressure (?P); b) input or determine a density value; c) input or determine a Q value; d) determine a first Cv value using the ?P, the density value, and the Q value; and e) actuate the choke valve to a first choke position associated with the first Cv value.

Abstract: A control system and method for a well drilling platform having a plurality well platform systems is provided. The control system includes at least one remote communication unit (RCU), and a controller. The controller is in communication with the well platform systems, and has at least one processor, and a memory device that is coupled to the processor and that stores the instructions. When executed by the processor, the instructions cause the controller to communicate with the well platform systems to receive information from one or more well platform systems and to send system control commands to the one or more well platform systems. The controller and the at least one RCU are configured to electronically communicate with one another information relating to at least one of the well platform systems.

Abstract: One or more techniques and/or systems are disclosed for detecting the presence or formation of a blockage in a sewer system using a machine learning (ML) model. The ML model may be trained using a supervised learning method; and may be used to analyze various inputs from a sewer system to automatically sense developing sewer blockages. The systems and techniques described herein may also indicate the type of blockage that is forming, such as silt accumulation; sediment buildup; ragging; root intrusion; fats, oils, and grease (FOG), etc.) prior to a full blockage to allow preventative cleaning operations.

Abstract: An autonomous drilling pressure control system for use with a drilling rig includes a pressure control device for controlling pressure within an annulus of an associated well, an electronic pressure sensor for monitoring pressure within the annulus, and an electronic position indicator for indicating a position of the pressure control device. A control subsystem independent of the drilling rig and responsive to the pressure sensor is provided for manipulating the pressure control device to control the pressure within the annulus of the associated well. At least one dedicated power source independent of the drilling rig supplies power to the pressure sensor and position indicator.

Abstract: A method of producing synergistic and enhanced efficacy in treating a disease in a subject includes providing an antibody, the antibody being a classic antibody or a modified biologic molecule that blocks a first target in the subject; providing a drug, the drug being a small molecule agent that blocks the first target or a second target in the subject; connecting the antibody and the drug with a linker to form an Antibody-Drug Synergism (ADS) compound; and treating the disease with the ADS compound. The linker is hydrolyzed in the subject over a certain time so that both the antibody and the drug exert their functions simultaneously, and the ADS compound confers better efficacy than either the antibody or the drug alone due to a synergism of the ADS compound.

Abstract: The present invention relates to a suspension comprising 50-95% by weight of the total suspension (w/w) of at least one metallic material and/or ceramic material and/or polymeric material and/or solid carbon containing material; and at least 5% by weight of the total suspension of one or more fatty acids or derivatives thereof. In addition, the invention relates to uses of such suspension in 3D printing processes.

Abstract: A galvanic isolation in the power electronics system of an electricity charging station having the following features: a rectifier (11) for connection of the charging station (10) to a public low-voltage network and a galvanically isolating DC voltage converter (12) having a high clock frequency and connected to the rectifier (11) and a corresponding electricity charging station.

Abstract: A modular rotating diverter head is disclosed for use on oil, gas or geothermal wells. While providing for sealing with or without rotation of the drill pipe, the head consists of a central housing body which has removable mounted flanges for vertical and horizontal use. The design enables the use of a multitude of different connectors and adapters as well as the replacement of these due to wear and tear without affecting the life and integrity of the central housing.

Abstract: A charging station for electric automobiles having a removable and/or folding hood and a circumferential sealing strip. The hood has a marginal sealing surface and the charging station is configured in such a way that the sealing strip and the sealing surface together form a continuous seal when the hood rests on the charging station.

Abstract: A level sensor and housing therefor, the level sensor provides a measurement of the depth in a sewer manhole or chamber. The level sensor includes an ultrasonic transducer that emits a signal to measure the liquid below and may use an additional transducer or it is used by itself to detect the signal reflected from the surface. A parabolic reflector is designed and arranged to direct the emitted ultrasonic signal from the transducer to the surface with a linear beam while minimizing the beam spread. The return echo may either be measured directly or with the same transducer that was used to transmit the ultrasonic signal. The narrow ultrasonic beam with limited spread will allow measuring level in a sewer manhole or confined chamber or any sewer where the level is measured close to a vertical wall.

Abstract: A charging station for electric automobiles having a variable number of power electronics modules and a variable number of charging connections electrically connected to the power electronics modules.

Abstract: A method, system and computing device for incorporating marketing into a user authentication enables valuable marketing information to be received from or provided to users, in an authentication context where the users are likely to be attentive and focused. Thus marketing information is likely to be thoroughly reviewed by the users, easily recalled by the users at a later time, and user profile data collected from the users is likely to be accurate. The method includes presenting an authentication challenge to a user of a computing device, the authentication challenge including a number of challenge elements; receiving a response to the authentication challenge from the user; and presenting a non-authentication marketing activity to the user, the non-authentication marketing activity including a number of activity elements, and where the activity elements correspond with the challenge elements.

Abstract: An auxiliary spare tire brake light comprising: (a) a support having a central portion and a peripheral portion; (b) an array of elongated openings in the central portion of the support positioned and sized to fit over a plurality of different configurations of the lugs at the back of the vehicle for positioning the support on the lugs behind the rim of the spare tire; (c) a plurality of lights arrayed in a substantially continuous ring around the peripheral portion of the support; (d) a wire electrically connected to the plurality of lights; and (e) an electrical connector on the end of the wire threaded through a hole in the peripheral portion with the wire.