Patents Assigned to Advanced Cardiovascular Systems
  • COATINGS OF ACRYLAMIDE-BASED COPOLYMERS
    Publication number: 20110293675
    Abstract: An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
    Type: Application
    Filed: August 9, 2011
    Publication date: December 1, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Thierry Glauser, Mikael O. Trollsas
  • Nitric oxide generating medical devices
    Patent number: 8067025
    Abstract: Medical devices having a catalyst capable of catalyzing the generation of nitric oxide attached to the medical device and methods of treating a vascular condition using the devices are provided.
    Type: Grant
    Filed: March 20, 2007
    Date of Patent: November 29, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Thierry Glauser, Stephen D. Pacetti, Paul Consigny
  • Assembly for manufacturing an implantable polymeric medical device
    Patent number: 8066762
    Abstract: A polymeric tube is positioned on a polymeric mandrel and then laser cut to form an implantable medical device, such as a stent. The method reduces contamination of the inner surface of the stent, which would be caused if conventional glass or metal mandrels are used, while simultaneously reducing damage to the inner surface of the stent due to the shielding effect of the polymeric mandrel.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: November 29, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Svava Maria Atladottir, David C. Gale, Klaus Kleine
  • Implantable medical devices incorporating plasma polymerized film layers and charged amino acids
    Patent number: 8067023
    Abstract: An implantable medical device, such as a stent, is disclosed comprising an amino acid or a polypeptide bonded to a plasma polymerized film layer formed on the device. A method of manufacturing the same is also disclosed.
    Type: Grant
    Filed: July 15, 2005
    Date of Patent: November 29, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Eugene T. Michal, Charles D. Claude
  • Stent mandrel fixture and method for selectively coating surfaces of a stent
    Patent number: 8061298
    Abstract: A stent mandrel fixture for supporting a stent during the application of a coating substance is provided. A method supporting a stent during the application of a coating substance is also provided.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: November 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jason Fox, Nathan Harold, Barry Templin, Andrew Tochterman
  • Abluminal, multilayer coating constructs for drug-delivery stents
    Patent number: 8062353
    Abstract: Implantable medical devices may include at least one structural element having an abluminal side, luminal side, and sidewalls between the abluminal and luminal sides. The coating may include at least two continuous coating layers. In some embodiments, the luminal side, and all or a majority of the sidewalls are free of at least two of the coating layers.
    Type: Grant
    Filed: November 12, 2009
    Date of Patent: November 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen Dirk Pacetti, Jessica DesNoyer, Yung-Ming Chen, Lothar Kleiner, Syed F. A. Hossainy
  • Methods for coating implantable medical devices
    Patent number: 8057844
    Abstract: Methods for coating an implantable medical device, such as a stent, are provided.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: November 15, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung-Ming Chen, Henjen Ho
  • Thermal treatment of a drug eluting implantable medical device
    Patent number: 8053019
    Abstract: A coating and a method of coating an implantable medical device, such as a stent, is disclosed. The method includes subjecting the coating to a thermal condition such as a temperature above the glass transition temperature of a polymer included in the coating.
    Type: Grant
    Filed: February 3, 2010
    Date of Patent: November 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Fuh-Wei Tang, Stephen D. Pacetti, Jeff Royal, Dorie M. Happ, Kurt Scheinpflug, Ty Hu
  • Mounting assembly for a stent and a method of using the same to coat a stent
    Patent number: 8051798
    Abstract: A mounting assembly for a stent and a method of coating a stent using the assembly are provided.
    Type: Grant
    Filed: January 27, 2010
    Date of Patent: November 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Charles Snyder, Anh Tran, Arthur J. Wen
  • Methods for fabricating coatings for drug delivery devices having gradient of hydration
    Patent number: 8052988
    Abstract: A method for fabricating a coating for an implantable medical device is provided comprising applying a first polymer on at least a portion of the device to form a first layer of the coating and applying a second polymer on at least a portion of the first layer to form a second layer of the coating. The second polymer has a higher degree of hydration than the first polymer. The first or second polymer can comprise a polyorthoester.
    Type: Grant
    Filed: January 18, 2008
    Date of Patent: November 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Syed F. A. Hossainy, Yiwen Tang, Andrew C. Tung, Thierry Glauser
  • Temperature controlled crimping
    Patent number: 8052912
    Abstract: This disclosure describes a method for crimping a polymeric stent onto a catheter for percutaneous transluminal coronary angioplasty or other intraluminal interventions. The method comprises crimping the stent onto a catheter when the polymer is at a target temperature other than ambient temperature. The polymer can optionally comprise drug(s).
    Type: Grant
    Filed: October 1, 2004
    Date of Patent: November 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang, Anthony Abbate, Stephen D. Pacetti
  • Reduced Temperature Sterilization of Stents
    Publication number: 20110268607
    Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Abigail Freeman, Daniel Castro, David C. Gale
  • Reduced Temperature Sterilization of Stents
    Publication number: 20110265426
    Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.
    Type: Application
    Filed: July 8, 2011
    Publication date: November 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Abigail Freeman, Daniel Castro, David C. Gale
  • Stent spin coating apparatus
    Patent number: 8042486
    Abstract: A system or device for spin coating an implantable medical device, such as a stent, is disclosed. The device includes a coating table to support the stent, the stent being positioned on top of the coating table and supported on the table by a support fixture. The coating table has an axis of rotation. The axis of rotation of the table can intersect a center of the mass of the stent. A driving means can be provided for rotating the stent about the longitudinal axis of the stent and for rotating the coating table about the axis of rotation.
    Type: Grant
    Filed: June 3, 2008
    Date of Patent: October 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • System for coating stents
    Patent number: 8042487
    Abstract: A system for coating implantable medical devices, such as stents, and a method of coating stents using the system is also disclosed. The system includes a barrier or barriers for isolating an area of the stent on which a composition for coating a stent is applied. Two coating compositions can be applied simultaneously to a stent by separate nozzles on different sides of a barrier. Cross-contamination of the compositions is prevented by the barrier.
    Type: Grant
    Filed: January 14, 2008
    Date of Patent: October 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Syed F. A. Hossainy
  • Stent mandrel fixture and method for coating stents
    Patent number: 8042485
    Abstract: A stent mandrel support for supporting a stent during the application of a coating substance is provided.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: October 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica R. DesNoyer, Stephen D Pacetti
  • Controlled deformation of a polymer tube with a restraining surface in fabricating a medical article
    Patent number: 8043553
    Abstract: Methods of manufacturing a medical article that include radial deformation of a polymer tube are disclosed. A medical article, such as an implantable medical device or an inflatable member, may be fabricated from a deformed tube.
    Type: Grant
    Filed: September 30, 2004
    Date of Patent: October 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Jonathan P. Durcan
  • Stent coatings incorporating nanoparticles
    Patent number: 8034361
    Abstract: Coatings for implantable medical devices including nanoparticles incorporating an active agent, and methods for fabricating the coatings.
    Type: Grant
    Filed: December 21, 2006
    Date of Patent: October 11, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Murthy V. Simhambhatla
  • Valve annulus constriction apparatus and method
    Patent number: 8034098
    Abstract: An apparatus is described for supporting and/or constricting a surface of a valve annulus. The apparatus includes a tubular member of dimensions suitable for insertion into a body vessel. The tubular member includes at least two first segments attachable to an interior wall of the body vessel. The tubular member further includes at least one second segment which is capable of decreasing its axial length to draw one of the first segments towards the other first segment.
    Type: Grant
    Filed: September 28, 2006
    Date of Patent: October 11, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Peter L. Callas, Richard J. Saunders
  • Implantable medical device comprising a pro-healing(ester-amide)
    Patent number: 8034364
    Abstract: The present invention relates to implantable medical devices, in particular stents, comprising pro-healing poly(ester-amide)s.
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: October 11, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica Reneé DesNoyer, Mikael Trollsas, Syed F. A. Hossainy