Patents Assigned to Advanced Cardiovascular Systems
  • Polysulfone block copolymers as drug-eluting coating material
    Patent number: 8017142
    Abstract: A polymeric composition comprising a polysulfone polymer and an elastomeric polymer for use as a coating composition for coating an implantable device, such as a DES, and methods of making and using the implantable device are provided.
    Type: Grant
    Filed: June 2, 2009
    Date of Patent: September 13, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Charles D. Claude, Ni Ding, Yeung Siu Yu
  • Coatings of acrylamide-based copolymers
    Patent number: 8017141
    Abstract: An implantable device including conjugate formed of an acrylamide-based copolymer and a bioactive agent is provided.
    Type: Grant
    Filed: December 15, 2006
    Date of Patent: September 13, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Thierry Glauser, Mikael O. Trollsas
  • Radiation Sterilization of Medical Devices
    Publication number: 20110211990
    Abstract: A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam.
    Type: Application
    Filed: April 28, 2011
    Publication date: September 1, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Abigail Freeman, Brian Riggs, Robert Harrison, Greg Simmons
  • HIGH-DENSITY LIPOPROTEIN COATED MEDICAL DEVICES
    Publication number: 20110212139
    Abstract: Method are disclosed for local and systemic administration HDL, recombinant HDL or HDLm for the prevention, treatment, or amelioration of a vascular disorder, disease or occlusion such as restenosis or vulnerable plaque.
    Type: Application
    Filed: May 6, 2011
    Publication date: September 1, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventor: Ni Ding
  • Method for coating implantable medical devices
    Patent number: 8007855
    Abstract: A method of coating an implantable medical device is disclosed, the method includes applying a composition onto the device and drying the composition at elevated temperature in an environment having increased relative humidity.
    Type: Grant
    Filed: July 5, 2007
    Date of Patent: August 30, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Pacetti
  • Medicated porous metal prosthesis
    Patent number: 8007529
    Abstract: A porous prosthesis for delivering a medication to the site of implantation. The prosthesis, such as a stent, includes a first porous region and a second porous region and is at least partially formed from a molybdenum-rhenium alloy. The porous regions can have different porosity. A stent includes first, second and third porous region, the first porous region being between the second and third porous regions, and a therapeutic agent is disposed in the first porous region. A stent can also include a solid core and inner and outer porous layers surrounding the core.
    Type: Grant
    Filed: August 1, 2008
    Date of Patent: August 30, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: John Y. Yan
  • Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same
    Patent number: 8007775
    Abstract: Polymers containing poly(hydroxyalkanoates) and agents for use with medical articles and methods of fabricating the same are disclosed. The medical article generally comprises an implantable substrate having a coating, and the coating contains a poly(hydroxyalkanoate).
    Type: Grant
    Filed: December 30, 2004
    Date of Patent: August 30, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti
  • System and method for coating implantable devices
    Patent number: 8007858
    Abstract: A method and system of coating an implantable device, such as a stent, are provided.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: August 30, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Wouter E. Roorda, Ni Ding
  • Mounting assembly for a stent and a method of using the same to coat a stent
    Patent number: 8007856
    Abstract: A mounting assembly for a stent and a method of coating a stent using the assembly are provided.
    Type: Grant
    Filed: October 26, 2009
    Date of Patent: August 30, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Charles Snyder, Anh Tran, Arthur J. Wen
  • Polymer-Bioceramic Composite Implantable Medical Devices
    Publication number: 20110207843
    Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.
    Type: Application
    Filed: May 5, 2011
    Publication date: August 25, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Yunbing Wang, Syed Faiyaz Ahmed Hossainy, Bin Huang, Garth L. Wilkes, Vincent J. Gueriguian
  • Biologically absorbable coatings for implantable devices and methods for fabricating the same
    Patent number: 8003123
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising a biologically degradable, biologically erodable, and/or biologically resorbable ABA or AB block copolymer. A biologically active agent can be conjugated to the block copolymer.
    Type: Grant
    Filed: May 5, 2008
    Date of Patent: August 23, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Eugene T. Michal, Yiwen Tang
  • Rotatable support elements for stents
    Patent number: 8003156
    Abstract: Various embodiments of methods and devices for coating stents are described herein.
    Type: Grant
    Filed: May 4, 2006
    Date of Patent: August 23, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Jason Van Sciver
  • Polymer-Bioceramic Composite Implantable Medical Device with Different Types of Bioceramic Particles
    Publication number: 20110202126
    Abstract: Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed.
    Type: Application
    Filed: April 28, 2011
    Publication date: August 18, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Yunbing Wang, David C. Gale, Syed F.A. Hossainy
  • POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY
    Publication number: 20110200660
    Abstract: A method of forming a coating on a medical device having a controlled morphology is described. A medical device having a controlled morphology is described.
    Type: Application
    Filed: February 28, 2011
    Publication date: August 18, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar Walter Kleiner, Jessica Reneé DesNoyer, Stephen Dirk Pacetti, Syed Faiyaz Ahmed Hossainy
  • Radiation Sterilization of Medical Devices
    Publication number: 20110200482
    Abstract: A method of radiation sterilizing a plurality of stent-catheter assemblies includes positioning a plurality of stent-catheter assemblies on a fixture, each of the stent catheter assemblies being arranged in a planar configuration and disposed in corresponding planar packages supported on the fixture, wherein the packages are stacked horizontally on the fixture, and wherein the stents of the assemblies are positioned at a position in each package such that the stents are exposed to the same or substantially the same radiation; and exposing the packages to an incoming radiation beam, the radiation beam being at an acute angle to the planes of the planar configuration of the assemblies, wherein the packages are arranged such that a front end of the stack faces the radiation beam and a back end of the stack faces away from the radiation beam.
    Type: Application
    Filed: April 28, 2011
    Publication date: August 18, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Abigail Freeman, Brian Riggs, Robert Harrison, Greg Simmons
  • Reduced temperature sterilization of stents
    Patent number: 7998404
    Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: August 16, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Abigail Freeman, Daniel Castro, David C. Gale
  • Delivery of a Stent at an Elevated Temperature
    Publication number: 20110196471
    Abstract: Methods and systems of delivering a stent at an elevated temperature are disclosed herein.
    Type: Application
    Filed: April 20, 2011
    Publication date: August 11, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Anthony J. Abbate, Jeffrey David Royal
  • Square-wave laser bonding
    Patent number: 7994449
    Abstract: The present invention provides a square-wave laser seal pattern made by first directing a laser beam onto an shaft while the shaft is moving in a horizontal direction relative to a laser device so as to create a horizontal laser seal bond segment. Next, with the shaft rotating about a shaft longitudinal axis, the laser beam is directed onto the shaft so as to create a vertical laser seal bond segment. By alternately creating and coupling together a plurality of horizontal and vertical laser seal bond segments, a square-wave laser seal is formed around a circumference of the shaft. The shaft's movement in a horizontal direction relative to a laser beam may be either at a constant speed or a variable speed so as to control the amount of laser energy heat impacting the shaft material.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: August 9, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica Chiu, Lara K. Suh, Arthur Wen
  • Drug Delivery After Biodegradation Of The Stent Scaffolding
    Publication number: 20110190875
    Abstract: Disclosed herein is a stent comprising: a bioabsorbable polymeric scaffolding; and a coating comprising a bioabsorbable material on at least a portion of the scaffolding, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the coating.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 4, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang
  • Fluid treatment of a polymeric coating on an implantable medical device
    Patent number: 7989018
    Abstract: A method for modifying a polymeric coating on an implantable medical device, such as a stent, is disclosed. The method includes application of a fluid to a wet or dry polymeric coating with and without drugs.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: August 2, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Andrew F. McNiven, Thomas D. Esbeck, Ni Ding, Stephen Pacetti, Syed F. A. Hossainy