Patents Assigned to Advanced Cardiovascular Systems
  • Reduced temperature sterilization of stents
    Patent number: 7998404
    Abstract: Methods and systems for reduced temperature radiation sterilization of stents are disclosed.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: August 16, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Abigail Freeman, Daniel Castro, David C. Gale
  • Delivery of a Stent at an Elevated Temperature
    Publication number: 20110196471
    Abstract: Methods and systems of delivering a stent at an elevated temperature are disclosed herein.
    Type: Application
    Filed: April 20, 2011
    Publication date: August 11, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Anthony J. Abbate, Jeffrey David Royal
  • Square-wave laser bonding
    Patent number: 7994449
    Abstract: The present invention provides a square-wave laser seal pattern made by first directing a laser beam onto an shaft while the shaft is moving in a horizontal direction relative to a laser device so as to create a horizontal laser seal bond segment. Next, with the shaft rotating about a shaft longitudinal axis, the laser beam is directed onto the shaft so as to create a vertical laser seal bond segment. By alternately creating and coupling together a plurality of horizontal and vertical laser seal bond segments, a square-wave laser seal is formed around a circumference of the shaft. The shaft's movement in a horizontal direction relative to a laser beam may be either at a constant speed or a variable speed so as to control the amount of laser energy heat impacting the shaft material.
    Type: Grant
    Filed: May 25, 2005
    Date of Patent: August 9, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica Chiu, Lara K. Suh, Arthur Wen
  • Drug Delivery After Biodegradation Of The Stent Scaffolding
    Publication number: 20110190875
    Abstract: Disclosed herein is a stent comprising: a bioabsorbable polymeric scaffolding; and a coating comprising a bioabsorbable material on at least a portion of the scaffolding, wherein the degradation rate of all or substantially all of the bioabsorbable polymer of the scaffolding is faster than the degradation rate of all or substantially all of the bioabsorbable material of the coating.
    Type: Application
    Filed: April 13, 2011
    Publication date: August 4, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang
  • Fluid treatment of a polymeric coating on an implantable medical device
    Patent number: 7989018
    Abstract: A method for modifying a polymeric coating on an implantable medical device, such as a stent, is disclosed. The method includes application of a fluid to a wet or dry polymeric coating with and without drugs.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: August 2, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Andrew F. McNiven, Thomas D. Esbeck, Ni Ding, Stephen Pacetti, Syed F. A. Hossainy
  • Method of using a mandrel to coat a stent
    Patent number: 7985440
    Abstract: A method of applying a coating to a stent supported by a mandrel is disclosed.
    Type: Grant
    Filed: September 7, 2005
    Date of Patent: July 26, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Mohammed E. Moein
  • Vascular delivery system for accessing and delivering devices into coronary sinus and other vascular sites
    Patent number: 7981152
    Abstract: A method for placing a device into a target vasculature. The method comprises accessing the target vasculature with an access guide catheter to sub-select a proximal portion of the target vasculature. A rail catheter is tracked into the access guide catheter to place the rail catheter more distally and into a distal portion of the target vasculature. The access guide catheter is removed. A delivery catheter is tracked over the rail catheter. The rail catheter is then removed. A device catheter having the device is placed into the delivery catheter and positioned at a desired location within the distal portion of the target vasculature.
    Type: Grant
    Filed: December 10, 2004
    Date of Patent: July 19, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: William E. Webler, Neil Becker, Gregory M. Hyde
  • Delivery system with variable delivery rate for deploying a medical device
    Patent number: 7976574
    Abstract: A delivery system utilizes a handle assembly including an actuating mechanism capable of initially providing sufficient mechanical advantage to overcome static friction when initiating deployment of the medical device. The actuating mechanism includes components which help to increase the speed of deployment as the physician continues to manipulate the actuating mechanism.
    Type: Grant
    Filed: August 8, 2008
    Date of Patent: July 12, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: John E. Papp
  • Abluminal stent coating apparatus and method of using focused acoustic energy
    Patent number: 7976891
    Abstract: The apparatus and method use an optical feedback system to align a transducer with a stent strut. Once alignment is achieved, the transducer causes a coating to be ejected onto the stent strut and the transducer is moved along the stent strut to coat the stent strut.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: July 12, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jason Van Sciver, Yung-Ming Chen, Lothar Kleiner
  • Manufacturing process for polymetric stents
    Patent number: 7971333
    Abstract: Methods and systems of fabricating a polymeric stent are disclosed herein. Methods are disclosed that include forming a polymeric tube using extrusion, radially deforming the formed tube so that the deformed tube comprises a target diameter, forming a stent from the deformed tube, and forming a stent from the deformed tube. The stent is formed by laser machining a stent pattern in the deformed tube with an ultra-short pulse laser. Disclosed methods further include crimping the stent on a support element, wherein a temperature of the stent during crimping is above an ambient temperature.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: July 5, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Bin Huang, Anthony J. Abbate, Timothy A. Limon, Klaus Kleine
  • Method of crimping a polymeric stent
    Patent number: 7966708
    Abstract: A method of crimping a stent to a support element is disclosed, the method comprising: positioning a polymeric stent around a support element; heating the stent, wherein the heated stent is above ambient temperature; and allowing the heated stent to radially contract onto the support element, wherein the heated stent radially contracts at least partially due to heating the stent.
    Type: Grant
    Filed: June 11, 2010
    Date of Patent: June 28, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, Patrick Wu
  • BALLOON CATHETER HAVING IMPROVED BALLOON SEAL
    Publication number: 20110152764
    Abstract: The end cap is preferably formed of a relatively high durometer material with an inner surface on an outer surface of the shaft and on an outer surface of the balloon skirt section, and contacts a compression member on the balloon outer surface. The configuration prevents or inhibits failure at the balloon seals which otherwise results from the compression member moving or the balloon pulling off the shaft and out from under the compression member during inflation of the balloon. As a result, the balloon catheter of the invention has an improved consistent burst pressure and/or failure mode.
    Type: Application
    Filed: March 3, 2011
    Publication date: June 23, 2011
    Applicant: ADVANCED CARDIOVASCULAR SYSTEMS, INC.
    Inventor: John Arthur Simpson
  • POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY
    Publication number: 20110153004
    Abstract: A method of forming a coating on a medical device having a controlled morphology is described. A method of treating a disorder in a patient using the medical device is described.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 23, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: LOTHAR WALTER KLEINER, JESSICA RENEE DESNOYER, STEPHEN DIRK PACETTI, SYED FAIYAZ AHMED HOSSAINY
  • POLY(ESTER AMIDE)-BASED DRUG DELIVERY SYSTEMS WITH CONTROLLED RELEASE RATE AND MORPHOLOGY
    Publication number: 20110151104
    Abstract: A method of forming a coating on a medical device having a controlled morphology is described.
    Type: Application
    Filed: February 28, 2011
    Publication date: June 23, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar Walter Kleiner, Jessica Reneé DesNoyer, Stephen Dirk Pacetti, Syed Faiyaz Ahmed Hossainy
  • Coating Construct With Enhanced Interfacial Compatibility
    Publication number: 20110144741
    Abstract: The present invention provides a method of forming a coating on a medical device having a topcoat and a basecoat and an improved compatibility between a topcoat and a basecoat on the medical device.
    Type: Application
    Filed: February 14, 2011
    Publication date: June 16, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar W. Kleiner, Jessica Renee DesNoyer, Syed Faiyaz Ahmed Hossainy
  • Polymer-bioceramic composite implantable medical devices
    Patent number: 7959940
    Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed.
    Type: Grant
    Filed: May 30, 2006
    Date of Patent: June 14, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: David C. Gale, Yunbing Wang, Syed Faiyaz Ahmed Hossainy, Bin Huang, Garth L. Wilkes, Vincent J. Gueriguian
  • High-density lipoprotein coated medical devices
    Patent number: 7959659
    Abstract: An implantable medical device is disclosed comprising a high-density lipoprotein (HDL), recombinant HDL, high-density lipoprotein mimics (HDLm), or a combination thereof. Method are also disclosed for local and systemic administration HDL, recombinant HDL or HDLm for the prevention, treatment, or amelioration of a vascular disorder, disease or occlusion such as restenosis or vulnerable plaque.
    Type: Grant
    Filed: December 29, 2004
    Date of Patent: June 14, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Ni Ding
  • Polymer-bioceramic composite implantable medical device with different types of bioceramic particles
    Patent number: 7955381
    Abstract: Implantable medical devices fabricated from polymer/bioceramic composites with different types of bioceramic particles are disclosed. The plurality of bioceramic particles can include acidic particles and basic particles, the acidic particles and basic particles having different particle size distributions. The degradation of a selected type of particle can be reduced or prevented during a selected time frame by encapsulating some or all of the selected type of particles with a bioabsorbable polymer.
    Type: Grant
    Filed: June 29, 2007
    Date of Patent: June 7, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yunbing Wang, David C. Gale, Syed F. A. Hossainy
  • Polycationic peptide coatings and methods of coating implantable medical devices
    Patent number: 7955615
    Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: June 7, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Eugene T. Michal, Syed F. A. Hossainy, Ni Ding, Wouter E. Roorda
  • Delivery of a stent at an elevated temperature
    Patent number: 7951185
    Abstract: Methods and systems of delivering a stent at an elevated temperature are disclosed herein. Methods of delivering a stent include allowing reactants to react within a delivery system exothermically. The heat generated from the exothermic reaction increase a temperature of a stent mounted on a support member. The increase in temperature increases the flexibility of the stent which reduces or eliminates formation of cracks in the stent when it expands. A system can include a first reactant disposed within at least a portion of the support member, a catheter in fluid communication with the support member, or both. The first reactant being disposed in such a way to react exothermically with a second reactant disposed within the delivery system.
    Type: Grant
    Filed: January 6, 2006
    Date of Patent: May 31, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Anthony J. Abbate, Jeffrey David Royal