Patents Assigned to Advanced Cardiovascular Systems
  • Medicated porous metal prosthesis and a method of making the same
    Patent number: 7931931
    Abstract: A porous prosthesis for delivering a medication to the site of implantation, and a method of making the same, is disclosed.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: April 26, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: John Y. Yan
  • Valve aptation assist device
    Patent number: 7927370
    Abstract: An apparatus including a tether, and an aptation device coupled to the tether at a position corresponding to a location to contact cusps of an atrioventricular valve during systole, wherein the tether and aptation device are suitable for percutaneous delivery to a patient. An apparatus including a support annulus comprising a length corresponding to a circumference of one of an interior portion of an atrium and an atrioventricular valve annulus; and an aptation device coupled to the support annulus corresponding to a location to contact cusps of an atrioventricular valve during at least one of systole when the support annulus is seated in one of an atrium and an atrioventricular valve annulus, wherein the support annulus and aptation device are suitable for percutaneous delivery to a patient. Also, a method of introducing an aptation device to contact cusps or leaflets of an atrioventricular valve.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: April 19, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: William E. Webler, James D. Breeding, Brad D. Bisson, Firas Mourtada, Gregory M. Hyde, Stephanie A. Szobota, Gabriel Asongwe, Jeffrey T. Ellis
  • Degradable polymeric implantable medical devices with continuous phase and discrete phase
    Patent number: 7923022
    Abstract: An implantable medical device is disclosed comprising: a structural element, wherein the structural element includes: a continuous phase comprising a first polymer of LPLG; a discrete phase within the continuous phase, wherein the discrete phase comprises a second polymer including rapidly eroding elastic discrete phase segments. The second polymer further includes anchor segments that have the same or substantially the same chemical make up as the first polymer of the continuous phase, and at least some of the anchor segments have partially or completely phase-separated from the discrete phase into the continuous phase.
    Type: Grant
    Filed: September 13, 2006
    Date of Patent: April 12, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yunbing Wang, David C. Gale
  • Stent mandrel fixture and method for reducing coating defects
    Patent number: 7918181
    Abstract: A stent mandrel fixture for supporting a stent during the application of a coating substance is provided.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: April 5, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Fuh-Wei Tang, Syed F. A. Hossainy, Dorrie Happ, Ty T. Hu
  • Coatings for implantable medical devices
    Patent number: 7919075
    Abstract: Polymer coatings for medical devices are disclosed. The polymers can include at least one unit derived from ethylene and at least one vinyl unit or acrylic unit. The coatings can have a biologically compatible compound conjugated to, or blended with, the polymer.
    Type: Grant
    Filed: March 20, 2002
    Date of Patent: April 5, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Eugene T. Michal, Syed F. A. Hossainy, Ashok Shah
  • Device for, and method of, blocking emboli in vessels such as blood arteries
    Patent number: 7918820
    Abstract: A filtering device has a directional member and filtering member disposable in a vessel (e.g. blood artery) at a position past a lesion in the direction of fluid flow. The filtering member is made from a resilient material having properties of passing the fluid while blocking the passage of emboli in the fluid. This material may be selected from a group consisting of blood filter material and a braided/woven biocompatible material with the properties specified above. The inner end of the filtering member is attached to a shaft which provides for the disposition of the members in the vessel at the position past the lesion and the withdrawal of the members from the vessel. The directional member has a length extending at least to the vessel wall. The directional member is made from a pliable and elongatable material with properties of blocking fluid and emboli passage.
    Type: Grant
    Filed: September 11, 2009
    Date of Patent: April 5, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Kent C. B. Stalker
  • Stent Fixture and Method for Reducing Coating Defects
    Publication number: 20110076386
    Abstract: A stent fixture for supporting a stent during formation of a coating is provided.
    Type: Application
    Filed: September 24, 2010
    Publication date: March 31, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung-Ming Chen, Allan Bradshaw, Philip C. Foreman, Greg Teaby
  • Selectively Coating Luminal Surfaces of Stents
    Publication number: 20110073036
    Abstract: With abluminal side of a stent masked, the luminal side of the stent is selectively coated with a substance, such as an anti-coagulant, a platelet inhibitor and/or a pro-healing substance. The stent can be masked by inserting it into a rigid mandrel chamber or by compressing a masking sleeve onto the outer side of the stent. A spray nozzle inserted into the masked stent spray coats the substance onto the luminal side. The sprayed coating can be cured onto the stent such as by inserting an electrical-resistance heater bar into the stent.
    Type: Application
    Filed: December 3, 2010
    Publication date: March 31, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Andrew J. Tochterman, William J. Fox, Nathan Harold
  • Balloon catheter having improved balloon seal
    Patent number: 7914643
    Abstract: The end cap is preferably formed of a relatively high durometer material with an inner surface on an outer surface of the shaft and on an outer surface of the balloon skirt section, and contacts a compression member on the balloon outer surface. The configuration prevents or inhibits failure at the balloon seals which otherwise results from the compression member moving or the balloon pulling off the shaft and out from under the compression member during inflation of the balloon. As a result, the balloon catheter of the invention has an improved consistent burst pressure and/or failure mode.
    Type: Grant
    Filed: February 1, 2010
    Date of Patent: March 29, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: John A. Simpson
  • Apparatuses and methods for heart valve repair
    Patent number: 7914577
    Abstract: A medical device for treating a defective heart valve. The medical device comprises a delivery sheath and an implantable device moveably disposed within the delivery sheath. The implantable device further comprises a distal expandable basket, a proximal expandable basket, and a connecting member coupling at a first end to the distal expandable basket and at a second end to the proximal expandable basket. Each of the distal expandable basket and proximal expandable basket is in a collapsed state during delivery and an expanded state after deployment. An actuator is releasably coupled to the implantable device. When coupled to the implantable device, the actuator can move the implantable device in a way to allow for positioning of the distal and proximal expandable baskets.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: March 29, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Daniel L. Cox
  • Coating For Implantable Devices And A Method Of Forming The Same
    Publication number: 20110070283
    Abstract: Coatings for implantable devices or endoluminal prosthesis, such as stents, are provided, including a method of forming the coatings. The coatings can be used for the delivery of an active ingredient or a combination of active ingredients.
    Type: Application
    Filed: March 12, 2010
    Publication date: March 24, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Stephen D. Pacetti, Keith E. Fong, Vinayak Bhat, Deborra Sanders Millare, Judy A. Guruwaiya, Daryush Mirzaee, Evagenia Mandrusov
  • Magnetic resonance imaging coils
    Patent number: 7912531
    Abstract: An apparatus including a device such as a catheter or guidewire having dimensions suitable for percutaneous delivery to a patient; and a magnetic resonance (MR) compatible antenna associated with the device in a manner that provides a prescribed radial and/or longitudinal orientation of the antenna at a point of interest within a blood vessel of a patient. An antenna suitable for radial and/or longitudinal orientation. A method including inserting a medical device having an antenna capable of transmitting radio frequency signals in a blood vessel of a patient and radially and/or longitudinally orienting the antenna at a point of interest within a blood vessel of a patient.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: March 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica G Chiu, Barabara E. Stamberg, Dagmar Bettina Beyerlein
  • Poly(ester amide)-based drug delivery systems with controlled release rate and morphology
    Patent number: 7910152
    Abstract: A method of forming a coating on a medical device having a controlled morphology is described.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: March 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar Walter Kleiner, Jessica Reneé DesNoyer, Stephen Dirk Pacetti, Syed Faiyaz Ahmed Hossainy
  • Clamp mandrel fixture and a method of using the same to minimize coating defects
    Patent number: 7901728
    Abstract: A mounting assembly for supporting a stent and a method of using the same to coat a stent is disclosed.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: March 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jason Van Sciver, Manish Gada, Jessie Madriaga
  • Ultrasound energy driven intraventricular catheter to treat ischemia
    Patent number: 7901359
    Abstract: A method and apparatus for improving blood flow to an ischemic region (e.g., myocardial ischemia) a patient is provided. An ultrasonic transducer is positioned proximate to the ischemic region. Ultrasonic energy is applied at a frequency at or above 1 MHz to create one or more thermal lesions in the ischemic region of the myocardium. The thermal lesions can have a gradient of sizes. The ultrasound transducer can have a curved shape so that ultrasound energy emitted by the transducer converges to a site within the myocardium, to create a thermal lesion without injuring the epicardium or endocardium.
    Type: Grant
    Filed: December 6, 2005
    Date of Patent: March 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Evgenia Mandrusov, Jeffrey Steward, Marshall Sherman
  • Polycationic peptides for cardiovascular therapy
    Patent number: 7901703
    Abstract: Implantable medical devices including polycationic peptide coatings are disclosed.
    Type: Grant
    Filed: March 23, 2007
    Date of Patent: March 8, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Syed F. A. Hossainy
  • Coating abluminal surfaces of stents and other implantable medical devices
    Patent number: 7892592
    Abstract: A sleeve is positioned over a radially-expandable rod assembly and a stent is positioned over the sleeve. A mandrel is inserted into the rod assembly to thereby press the sleeve against the inner surface of the stent and expand the stent. A coating (such as a solvent, a polymer and/or a therapeutic substance) is then applied to the outer (abluminal) surfaces of the stent, by spraying, for example. The sleeve advantageously prevents the coating material from being applied to inner (luminal) surfaces of the stent and also allows the coating material to be efficiently applied to the abluminal surfaces.
    Type: Grant
    Filed: November 30, 2004
    Date of Patent: February 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Yung Ming Chen, Jeff H. Smith, Celenia Gutierrez
  • Method of making a non-compliant balloon for a catheter
    Patent number: 7892469
    Abstract: An intravascular catheter system for properly implanting a stent in a body lumen generally comprising a catheter having an elongated shaft with an inflatable balloon formed of compliant material and a stent mounted on the working length of the balloon. The balloon material is compliant within the working range of the balloon to provide substantial radial expansion. The wingless radially expansive balloon expands in a uniform manner, thereby producing uniform expansion and implantation of the stent. Another embodiment is directed to a balloon catheter, having a semi-compliant balloon or a noncompliant balloon formed at least in part of a block copolymer.
    Type: Grant
    Filed: March 16, 2004
    Date of Patent: February 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Florencia Lim, NianJiong Bei, Chi Le Long
  • Component for delivering and locking a medical device to a guide wire
    Patent number: 7892251
    Abstract: A locking component delivers and locks an attached medical device along a pre-deployed guide wire. The locking component can lock onto a flexible body member disposed on the guide wire, such as the distal helical tip coil of a conventional guide or a specially-designed guide wire. The locking component includes a tapered opening which temporarily compresses a portion of the helical coil and a locking recess in communication with the tapered opening for receiving the compressed coil. Compressed coils which enter the locking recess will spring back to their original shape (diameter) within the locking recess, locking the component to the coil.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: February 22, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Brad Kellerman, David H. Burkett, Robert Hayzelden
  • Stent crimping apparatus and method
    Patent number: 7886419
    Abstract: A method for crimping a stent onto a balloon includes inflating a balloon with a fluid, sliding a stent over the inflated balloon, crimping the stent onto the balloon, and controlling the pressure inside the balloon below a given value when the stent is being crimped onto the balloon.
    Type: Grant
    Filed: July 18, 2006
    Date of Patent: February 15, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale, Daniel Castro