Patents Assigned to Advanced Cardiovascular Systems
  • Infusion treatment agents, catheters, filter devices, and occlusion devices, and use thereof
    Patent number: 7887661
    Abstract: Embodiments include an infusion-occlusion system having a delivery catheter, a guide catheter adapted to receive the delivery catheter, and a guidewire with an occlusion device adapted to be received within the guide catheter. The guide catheter of the catheter kit may be provided with an occlusion device at the distal end of the guide catheter. The delivery catheter may have an accessory lumen, coaxial or co-linear lumen, a supporting mandrel, or an occlusion device at its distal end. Moreover, according to some embodiments, occlusion devices may be a single material or a composite balloon having an inner liner and an outer layer of different materials, a high compliance low pressure balloon, or a filter device that restricts particles from passing through but does not restrict fluid, such as blood. An inflation device with a large volume and low volume syringe can be used to inflate the balloon.
    Type: Grant
    Filed: October 24, 2007
    Date of Patent: February 15, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Jessica G. Chiu, Gregory Waimong Chan, Gabriel Asongwe, Robert C. Esselstein, Douglas Gesswein, Srinivasan Sridharan, Nianjiong Joan Bei, William E. Webler, Stephen G. Schaible, Mina Chow, Yan Shen, Hongzhi Bai, Mark J. Bly, Thomas R. Hatten
  • Implantable devices for accelerated healing
    Patent number: 7887572
    Abstract: Implantable devices (e.g., stent) having a protein patterning or bioactive patterning for accelerated healing and method of forming and using the same are provided.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: February 15, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Florian Niklas Ludwig, David Gale
  • Method and system for irradiation of a drug eluting implantable medical device
    Patent number: 7887871
    Abstract: A method and system for modifying a drug delivery polymeric substrate for an implantable device, such as a stent, is disclosed.
    Type: Grant
    Filed: August 28, 2008
    Date of Patent: February 15, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Houdin Dehnad
  • Methods, Compositions and Devices for Treating Lesioned Sites Using Bioabsorbable Carriers
    Publication number: 20110027188
    Abstract: An implantable medical device is disclosed having a plurality of smaller particles contained in a plurality of larger particles and configured to be released from the larger particles when the device is implanted in a patient. The smaller particles and the larger particles are made of bioabsorbable metal, glass or ceramic. A substance can be associated with the smaller particles. The larger particles can be embedded within at least a portion of the device.
    Type: Application
    Filed: October 8, 2010
    Publication date: February 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Lothar W. Kleiner, Syed Hossainy, Irina Astafieva, Stephen Pacetti, Thierry Glauser, Jessica DesNoyer, Florian N. Ludwig
  • COATINGS FOR IMPLANTABLE DEVICES COMPRISING POLYMERS OF LACTIC ACID AND METHODS FOR FABRICATING THE SAME
    Publication number: 20110027336
    Abstract: Coatings for an implantable medical device and a method of fabricating thereof are disclosed, the coatings comprising polymers of lactic acid.
    Type: Application
    Filed: April 19, 2010
    Publication date: February 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F.A. Hossainy, Yiwen Tang, Eugene T. Michal, Thierry Glauser, Stephen D. Pacetti, Jessica DesNoyer
  • Surface Treatment of a Polymeric Stent
    Publication number: 20110028072
    Abstract: Methods of treating the polymeric surfaces of a stent with a fluid including a solvent for the surface polymer are disclosed.
    Type: Application
    Filed: October 11, 2010
    Publication date: February 3, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale, Daniel Castro, Timothy A. Limon
  • Locking component for an embolic filter assembly
    Patent number: 7879065
    Abstract: A locking component for locking a medical device onto a guide wire. Such medical devices include, for example, an embolic filter assembly used to capture embolic material that may be created and released into a patient's vasculature during a stenting or angioplasty procedure. The embolic filter assembly tracks along the guide wire, and is delivered to a treatment site where it is locked in place and deployed. The locking component enables the filter assembly to lock onto any standard guide wire, and does not require a modified guide wire that has a specially-designed fitting or stop to accomplish the locking function.
    Type: Grant
    Filed: January 26, 2007
    Date of Patent: February 1, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Douglas H. Gesswein, David K. Wrolstad, David H. Burkett, Robert C. Esselstein, Kathern J. Lind, Pablito Buan, Robert C. Hazelden, Thomas Tokarchik, III, Ryan Grandfield, Aaron Baldwin, Wayne E. Cornish, Philip S. Yip
  • Support device for a stent and a method of using the same to coat a stent
    Patent number: 7879386
    Abstract: A support device for a stent and a method of coating a stent using the device are provided.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: February 1, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Plaridel K. Villareal
  • Biobeneficial polyamide/polyethylene glycol polymers for use with drug eluting stents
    Patent number: 7879953
    Abstract: This disclosure provides a medical device and a method of forming the medical device. The medical device comprises a coating comprising a type-one polymer and a type-two polymer. The type-one polymer comprises at least two different blocks, at least one L1 block with the formula ; and at least one L2 block with the formula Medical devices comprising these polymers, mixtures of these polymers with therapeutic agents, and methods of making these polymers and mixtures are within the scope of this disclosure.
    Type: Grant
    Filed: July 28, 2010
    Date of Patent: February 1, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen D. Pacetti
  • Guidewire having linear change in stiffness
    Patent number: 7878985
    Abstract: The invention is directed to a guidewire having a distal section with multiple distally tapered core segments with at least two contiguous distally tapering core segments in which the most distal tapered core segment preferably has a greater degree of taper than the proximally contiguous tapered core segment. The invention is also directed to an elongated intracorporeal device, preferably a guidewire or section thereof, that has a core member with a plurality of contiguous tapered segments having taper angles that are configured to produce a linear change in stiffness over a longitudinal section of the device. The device may also have a core section with a continuously changing taper angle to produce a curvilinear profile that preferably is configured to produce a linear change in stiffness of the core over a longitudinal section of the device.
    Type: Grant
    Filed: September 11, 2003
    Date of Patent: February 1, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Wayne E. Cornish, John Schreiner, James Jacobs, Marc M. Jalisi, Mark T. Richardson, Kent C. Stalker, Olin J. Palmer
  • Biodegradable polymers for use with implantable medical devices
    Patent number: 7875283
    Abstract: The present invention relates to a stent fabricated of or coated with a composition comprising a biodegradable hydrophobic polymer containing water-labile bonds such that a device fabricated of the composition or the surface of a device coated with the requisite mechanical characteristics required of a stent and the polymer erodes from its outer surface inward.
    Type: Grant
    Filed: June 16, 2005
    Date of Patent: January 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Syed F. A. Hossainy, Debashis Dutta
  • Method of fabricating a biaxially oriented implantable medical device
    Patent number: 7875233
    Abstract: Methods of manufacturing a radially expandable stent, including radial expansion and axial elongation of a polymer tube, are disclosed.
    Type: Grant
    Filed: July 18, 2005
    Date of Patent: January 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale
  • Block copolymers of acrylates and methacrylates with fluoroalkenes
    Patent number: 7875073
    Abstract: A block copolymer comprising a fluorinated block and a non-fluorinated block and method of making the block copolymer are provided. Also provided herein are a coating on an implantable device comprising the block copolymer and method of using the implantable device.
    Type: Grant
    Filed: November 21, 2006
    Date of Patent: January 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Charles D. Claude
  • Polycationic peptide coatings and methods of coating implantable medical devices
    Patent number: 7875286
    Abstract: Coatings for medical devices which include polycationic peptides such as L-arginine and methods for fabricating the coatings are disclosed.
    Type: Grant
    Filed: August 26, 2005
    Date of Patent: January 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Stephen D. Pacetti, Eugene T. Michal, Syed F. A. Hossainy, Ni Ding, Wouter E. Roorda
  • Medicated coatings for implantable medical devices having controlled rate of release
    Patent number: 7875285
    Abstract: A coating for a medical device, particularly for a drug eluting stent, is described. The coating can include a polymer having in a dry state a glass transition temperature within a range of between about 20° C. and about 55° C.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: January 25, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Wouter E. Roorda, Ni Ding, Stephen D. Pacetti
  • Copolymer-Bioceramic Composite Implantable Medical Devices
    Publication number: 20110015726
    Abstract: Methods and devices relating to polymer-bioceramic composite implantable medical devices are disclosed. The bioceramic comprises calcium sulfate.
    Type: Application
    Filed: August 2, 2010
    Publication date: January 20, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Yunbing Wang, David C. Gale
  • Stent coating method
    Patent number: 7871658
    Abstract: A system, nozzle assembly, and method for coating a stent with a solvent and polymer are provided. The polymer can include a therapeutic substance or a drug. The polymer and solvent can be discharged from separate tubes disposed within another tube carrying moving air. The polymer and the solvent mix together when they are discharged and are atomized by the air. The ends of the tubes can be concentric with each other.
    Type: Grant
    Filed: February 6, 2008
    Date of Patent: January 18, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventor: Stephen Dirk Pacetti
  • Fiber Reinforced Composite Stents
    Publication number: 20110009948
    Abstract: Polymeric composite stents reinforced with fibers for implantation into a bodily lumen are disclosed.
    Type: Application
    Filed: September 9, 2010
    Publication date: January 13, 2011
    Applicant: Advanced Cardiovascular Systems, Inc.
    Inventors: Bin Huang, David C. Gale, Srinivasan Sridharan, Joseph R. Callol, Klaus Kleine, Syed F. A. Hossainy, Timothy A. Limon, Anthony J. Abbate
  • Method of manufacturing a stent coating
    Patent number: 7867549
    Abstract: A method of manufacturing a drug-delivery coating for a stent is disclosed. The method comprises covering the outer surface of the stent; applying a first composition to the inner surface of the stent to form a first coating; covering the first coating on the inner surface of the stent; and applying a second composition to the outer surface of the stent to form a second coating.
    Type: Grant
    Filed: October 23, 2009
    Date of Patent: January 11, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Evgenia Mandrusov, Paul Consigny, Syed Hossainy, Dary Mirzaee
  • Selectively coating luminal surfaces of stents
    Patent number: 7867547
    Abstract: With abluminal side of a stent masked, the luminal side of the stent is selectively coated with a substance, such as an anti-coagulant, a platelet inhibitor and/or a pro-healing substance. The stent can be masked by inserting it into a rigid mandrel chamber or by compressing a masking sleeve onto the outer side of the stent. A spray nozzle inserted into the masked stent spray coats the substance onto the luminal side. The sprayed coating can be cured onto the stent such as by inserting an electrical-resistance heater bar into the stent.
    Type: Grant
    Filed: December 19, 2005
    Date of Patent: January 11, 2011
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Andrew J. Tochterman, William J. Fox, Nathan Harold