Patents Assigned to Agilent Technologies
  • Monomer compositions for the synthesis of polynucleotides, methods of synthesis, and methods of deprotection
    Patent number: 8202985
    Abstract: Nucleotide monomers, polynucleotides, methods of making each, and methods of deprotecting each, are disclosed. An embodiment of the nucleotide monomer, among others, includes a nucleotide monomer having a heterobase protecting group selected from structures I through III as described herein. An embodiment of the polynucleotide, among others, includes a plurality of nucleotide moieties having a heterobase protecting group selected from one of structures I through III as described herein.
    Type: Grant
    Filed: March 23, 2006
    Date of Patent: June 19, 2012
    Assignees: Agilent Technologies, Inc., The Regents of the University of Colorado
    Inventors: Douglas J. Dellinger, Zoltan Timar, Agnieszka Sierzchala, Geraldino Dellinger, Marvin H. Caruthers
  • Thiocarbon-protecting groups for RNA synthesis
    Patent number: 8202983
    Abstract: Aspects of the invention include 2? protected nucleoside monomers that are protected at the 2? site with thiocarbon protecting groups. Thiocarbon protecting groups of interest include thiocarbonate, thionocarbonate, dithiocarbonate groups, as well as thionocarbamate protecting groups. Aspects of the invention further include nucleic acids that include the protecting groups of the invention, as well as methods of synthesizing nucleic acids using the protecting groups of the invention.
    Type: Grant
    Filed: May 9, 2008
    Date of Patent: June 19, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Douglas J. Dellinger, Agnieszka Sierzchala, John Turner, Joel Myerson, Zoltan Kupihar, Fernando Ferreira, Marvin H. Caruthers, Geraldine F. Dellinger
  • Three dimensional RF search system
    Patent number: 8199053
    Abstract: An RF signal detection process by incorporating direction detection of the RF signal along with energy detection to arrive at a signal of interest (SOI). The SOI is identified by matching direction detections and energy detections. Low-level and noise-like signals can be reevaluated for unresolved direction detections or energy detections. The RF signal detections can be filtered based on valid direction detections very early on in the processing chain to reduce the amount down-stream processing required.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: June 12, 2012
    Assignee: Agilent Technologies, Inc.
    Inventor: Michael G. Gribler
  • Efficient implementation of filters for MIMO fading
    Patent number: 8200729
    Abstract: A single finite impulse response filter designed to operate on a single signal is used in conjunction with an input multiplexer that interleaves samples from multiple signals and an output decimator. The output of the decimator contains interleaved samples of the multiple signals with independent filtering applied to each.
    Type: Grant
    Filed: October 25, 2006
    Date of Patent: June 12, 2012
    Assignee: Agilent Technologies, Inc.
    Inventor: Howard E. Hilton
  • Converging multipole ion guide for ion beam shaping
    Patent number: 8193489
    Abstract: A multipole ion guide comprises rods disposed about an axis, each of the rods having a first end and a second end remote from the first end. Each of the rods is disposed at a respective greater distance from the axis at the first end than at the second end. The multipole ion guide comprises means for applying a radio frequency (RF) voltage between adjacent pairs of rods, wherein the RF voltage creates a multipole field in a region between the rods; and means for applying a direct current (DC) voltage drop along a length of each of the rods. A mass spectroscopy system is also disclosed.
    Type: Grant
    Filed: May 28, 2009
    Date of Patent: June 5, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: James L. Bertsch, Michael Ugarov
  • PRESSURIZING SAMPLE LOOP BY SAMPLE METERING DEVICE
    Publication number: 20120132013
    Abstract: A sample injector (200) for use in a fluid separation system (10) for separating compounds of a fluidic sample in a mobile phase, the sample injector (200) comprising a switchable valve (202), a sample loop (204) in fluid communication with the valve (202) and configured for receiving the fluidic sample, a metering device (206) in fluid communication with the sample loop (204) and configured for introducing a metered amount of the fluidic sample on the sample loop (204), and a control unit (208) configured for controlling switching of the valve (202) to transfer the sample loop (204) between a low pressure state and a high pressure state via an intermediate state and for controlling the metering device (206) during the intermediate state to at least partially equilibrate a pressure difference in the sample loop (204) between the low pressure state and the high pressure state.
    Type: Application
    Filed: June 3, 2009
    Publication date: May 31, 2012
    Applicant: AGILENT TECHNOLOGIES, INC.
    Inventors: Bernd Glatz, Wolfgang Kretz
  • Automatic placement of measurement gates
    Patent number: 8185330
    Abstract: A method and apparatus is provided for setting time positions of measurement gates on a signal under test. Signal transition data is calculated by a processor for multiple signal transitions. Measurement gate start and end positions are set relative to the multiple signal transitions based on the received signal transition data.
    Type: Grant
    Filed: March 26, 2008
    Date of Patent: May 22, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Ling Ling Lye, Fook Shian Toong, Eric Breakenridge, Su Ann Lim
  • In-situ crystalline material screening apparatus and method
    Patent number: 8182607
    Abstract: There is provided a method and apparatus for assessing in-situ crystal formation in a test sample. Both optical imaging and X-ray diffraction techniques are utilized, with the results of these processes being combined in such a way as to produce an overall score relating to the aptness of crystalline material for harvesting and subsequent X-ray crystallography.
    Type: Grant
    Filed: December 13, 2006
    Date of Patent: May 22, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Damian Kucharczyk, Richard Cooper, Paul William Loeffen
  • Primary piston correction during transfer
    Patent number: 8182680
    Abstract: A method for controlling operation of a pump unit, where the pump unit includes a primary piston pump having a primary piston and a secondary piston pump having a secondary piston. The primary piston pump is fluidically connected with the secondary piston pump. The primary piston pump includes an inlet valve and an outlet valve, and the pump unit operates periodically according to a pump cycle. The method includes determining a fluid pressure of fluid dispensed by the pump unit, and performing a closed loop control of a position of the primary piston in dependence on the fluid pressure of the fluid dispensed by the pump unit during a first time interval of the pump cycle.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: May 22, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Philip Herzog, Konstantin Choikhet, Klaus Witt, Herbert Anderer
  • PEAK CORRELATION AND CLUSTERING IN FLUIDIC SAMPLE SEPARATION
    Publication number: 20120116689
    Abstract: A device (100) for analyzing measurement data having a plurality of data sets (206), each data set (206) being assigned to a respective one of a plurality of measurements, each data set (206) having multiple features (208) being indicative of different fractions of a fluidic sample, the device (100) comprising a cluster determining unit (108) configured for determining feature clusters (350) by clustering features (208) from different data sets (206) presumably relating to the same fraction, a spread determining unit (110) configured for determining for at least a part of the feature clusters (350) a spread (352) of the features (208) within a respective feature cluster (350), and a display unit (112) configured for displaying at least the part of the feature clusters (350) together with a graphical indication of the corresponding spread (352).
    Type: Application
    Filed: October 4, 2011
    Publication date: May 10, 2012
    Applicant: AGILENT TECHNOLOGIES, INC.
    Inventors: Gerd Heinje, Rainer Jaeger
  • Linear ion processing apparatus with improved mechanical isolation and assembly
    Patent number: 8173976
    Abstract: An ion processing apparatus includes a plurality of electrodes, first and second insulators, a housing, and a plurality of compliant first supports and second supports. Each electrode has a length along a central axis, and includes a first end region and an axially opposing second end region. The first and second insulators are coaxially disposed about the first and second end regions, respectively. The housing is coaxially disposed about the electrodes, the first insulator and the second insulator. The first supports extend between, and into contact with, the first insulator and the housing. The second supports extend between, and into contact with, the second insulator and the housing. The supports isolate the electrodes from external forces.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: May 8, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Bert David Egley, August Specht, Kenneth Newton, Dave Deford
  • Analyzer for signal anomalies
    Patent number: 8175829
    Abstract: A signal analyzer includes a divergence detector for detecting periodic interference in a signal, an information detector for detecting a random event in the signal, and output circuitry for providing compensation for the periodic interference and the random event.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: May 8, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Mostafa Afgani, Sinan Sinanovic, Harald Haas
  • Method for manufacturing the rotor assembly of a rotating vacuum pump
    Patent number: 8167576
    Abstract: A rotor assembly for rotary vacuum pumps has improved mechanical characteristics and low manufacturing cost due to a one-step thermal coupling of a rotor having a male axial projection and its supporting shaft having an end portion comprising a female cavity with a shape and size for receiving the male projection with interference at an ambient temperature. The rotor and the shaft are made of different materials. Heating of the end portion of the shaft provides expansion of the female cavity and allows for inserting the mail projection of the rotor into the female cavity of the shaft. By cooling the end portion to the ambient temperature the contraction of the cavity is obtained forming fixed interference coupling between the shaft and the rotor, where the end portion of the shaft contracts and compresses about the male axis projection of the rotor.
    Type: Grant
    Filed: February 25, 2009
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Gianluca Buccheri, Aldo Crisi, Vincenzo Pandolfo
  • Behavioral model generation
    Patent number: 8170854
    Abstract: A model of a device is generated. An input port of the device is stimulated with a large amplitude signal having a central frequency. A first port of the device is perturbed with a small amplitude signal tone. The small amplitude signal tone is at a frequency offset slightly from a harmonic of the central frequency. Spectral component frequencies of a resulting signal from the device are obtained to determine model coefficients for the device. At least some of the spectral component frequencies occur at frequencies offset slightly from harmonics of the central frequency.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: David E. Root, David D. Sharrit, John Wood
  • Microfluidic apparatuses with nanochannels
    Patent number: 8168140
    Abstract: In some embodiments of the present invention, the buried silicon oxide technology is employed in the fabrication of fluid channels, particularly nanochannels. For example, a fluid channel can be made in a buried silicon oxide layer by etching the buried oxide layer with a method that selectively removes silicon oxide but not silicon. Thus, one dimension of the resulting fluid channel is limited by the thickness of the buried oxide layer. It is possible to manufacture a very thin buried oxide layer with great precision, thus a nanochannel can be fabricated in a controlled manner. Moreover, in addition to buried oxide, any pairs of substances with a high etch ratio with respect to each other can be used in the same way. Further provided are the fluid channels, apparatuses, devices and systems comprising the fluid channels, and uses thereof.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Timothy Beerling, Karsten G. Kraiczek, Reid A. Brennen
  • Code domain power display
    Patent number: 8170543
    Abstract: A method for displaying multiple orthogonal code layers on a display device wherein a first axis is indicative of the identity of the code channel of a signal and a second axis is indicative of a measured value of the code channel signal. The method includes displaying a bar for each of a plurality of base code channel signals, the bar having a position on the first axis corresponding to the base code index of the base code channel signal and a height with respect to the second axis corresponding to a measured value of the base code channel signal; and displaying a tie line for each group of base code channels in an active channel, the tie line being located intermediately to the ends of the bars.
    Type: Grant
    Filed: April 14, 2006
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventor: Nimish R. Shah
  • Nestable, stackable pipette rack for nestable pipette tips
    Patent number: 8168137
    Abstract: The pipette rack comprises a plate, a peripheral base and a peripheral skirt. The plate has a first surface and defines an array of tip receptacles extending therethrough in a first direction orthogonal to the first surface. The tip receptacles are contoured to provide a clearance fit at locations axially offset from one another along a part of a pipette tip. The base extends in the first direction from the plate to a distal end surface. The skirt extends in the first direction from the base, and is outwardly offset therefrom to expose the distal end surface of the base so that the distal end surface contacts the plate of a similar pipette rack when the pipette racks are stacked.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: William Ryan Powell, Ian Yates
  • Interferometer step scanning systems and methods
    Patent number: 8169616
    Abstract: In some embodiments, the pathlength difference (retardation) in a step scanning infrared (IR) spectrometer interferometer is maintained under AC servomechanism (servo) control for a first period following a step change, and under DC servo control for a second period following the first period. Data is acquired during and/or after the DC servo control period. Switching off the AC servo control prior to data acquisition allows limiting the dither-frequency noise that could otherwise affect signals of interest, particularly in fast-time-scale applications such as high-speed time-resolved spectroscopy (TSR). A mirror position control circuit controls a mirror position stepping as well as switching a mirror servo control from AC to DC.
    Type: Grant
    Filed: February 16, 2010
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies Australia (M) Pty Ltd
    Inventors: David B. Johnson, Anthony Bond
  • Test sequencer and method for management and execution of sequence items
    Patent number: 8171455
    Abstract: A test sequencer software application and method for management and execution of sequence items. The test sequencer software application includes a management module and an execution module. The management module has capabilities of obtaining multiple sequence items definitions, of obtaining configuration information, of creating multiple lists of ordered sequence items from the sequence items definitions, and of separately linking each list of sequence items to one of multiple sequence engines from the configuration information. The execution module includes a sequencer controller module and the multiple sequence engines. The sequence controller module activates each of the multiple sequence engines in a preselected order and each sequence engine executes the ordered sequence items in each list linked to that sequence engine.
    Type: Grant
    Filed: August 13, 2004
    Date of Patent: May 1, 2012
    Assignee: Agilent Technologies, Inc.
    Inventor: Thomas R. Fay
  • Liquid chromatograph
    Patent number: D661607
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: June 12, 2012
    Assignee: Agilent Technologies, Inc.
    Inventors: Raoul Dinter, Helen Seebacher, Manuela Senf