Abstract: A liquid chromatography device (200) being controllable for executing a chromatographic method (402) defined by a set of target parameters and by a corresponding target sequence of operation procedures, the device comprising a method execution unit (202) configured for executing the chromatographic method (402) by applying the set of target parameters and by running the corresponding target sequence of operation procedures within the liquid chromatography device (200), a determining unit (204) configured for determining a deviation of an actual result of the chromatographic method (402) from an expected target result, wherein the expected target result of the chromatographic method (402) represents a desired behavior of the liquid chromatography device (200) and wherein the actual result of the chromatographic method (402) is obtained by executing the chromatographic method (402) and represents an actual behavior of the liquid chromatography device (200), and an adjusting unit (206) configured for adjusting a

Abstract: A device receives a data signal and a reference timing signal provided from a first clock. The device includes a sample clock that operates independently from the first clock, wherein the sample clock outputs a sample clock signal that is asynchronous with the reference timing signal; a sampler for sampling a data signal in accordance with the sample clock signal and outputting a sampled data signal; and a resampler for resampling the sampled data signal according to a resampling ratio and outputting a resampled data signal such that a number of data samples in the resampled data signal within a synchronization time interval defined with respect to the reference timing signal equals a nominal number of data samples that would occur in the sampled data signal within the synchronization time interval when the sample clock signal was synchronized to the reference timing signal.

Abstract: An apparatus is used for determining at least one parameter relating to an elongate member disposed within a vessel. The apparatus includes at least one measurement unit having a light emitting component and a corresponding light receiving component. The light receiving component is positioned apart from the light emitting component such that the elongate member is positionable between the light emitting component and the light receiving component. Additionally, the light emitting component is adapted to emit light towards the light receiving component, and the light receiving component is adapted to generate a signal corresponding to the light received from the light emitting component. A method for determining at least one parameter relating to the elongate member disposed within the vessel is also provided.

Abstract: The present invention relates to an improved system for efficiently and accurately performing immunoassays, such as ELISAs. The invention provides an immunoassay assembly which includes a flow-through unit and an aspiration pump. The immunoassay flow-through unit includes an outer seal; at least one bed support; an inner seal; and a packed non-porous bed. The unit is releasably attached to an aspiration pump which enables the controlled flow rate of liquid passing through the packed bed of the flow-through unit. The invention also provides a method of using the immunoassay assembly to identify analytical targets of interest.

Abstract: An electron capture dissociation apparatus comprises ion guide electrodes, an electron emitter, and an electron control device. The ion guide electrodes are arranged along a central axis and spaced circumferentially to circumscribe an interior space extending along the central axis. The electron emitter is disposed outside the interior space. The electron control device is configured for focusing an electron beam from the electron emitter toward the central axis, along a radial electron beam direction between two of the ion guide electrodes, and for decelerating the electron beam in a DC decelerating field of adjustable voltage potential directed along the electron beam direction.

Abstract: A molecular spiral-type vacuum pumping stage comprises a rotor disk having smooth surfaces cooperating with a stator. The stator is provided with a plurality of spiral channels at least on the surface facing the rotor disk, wherein the gas to be pumped flows in centripetal direction. The cross-section area (?) of the channels is reduced from the center towards the outer periphery of the stator. Due to this arrangement, it is possible to avoid the reduction of the internal gas flow velocity along the pumping stage and the related risk of internal compression or re-expansions, this limiting the power losses. The present invention also refers to a vacuum pump comprising at least one pumping stage as described above.

Abstract: A cover for sealing a container and preferably containers for a well plate. The cover is comprised of at least a top layer and a bottom layer structured in a way to form a recloseable aperture. Preferably, each of the layers comprise a recloseable aperture structured as flap, damper, baffle or butterfly valve respectively, wherein the recloseable apertures are arranged on top of each other. In a preferred embodiment of the invention a third moveable layer is arranged between the top and the bottom layer. By moving the middle layer, the aperture in the cover can be closed.

Abstract: The translation apparatus comprises an elongate track, an elongate fixed member and a stage. The fixed member extends parallel to the track in a fixed lengthwise position relative to the track. The stage is mounted on the track and is capable of movement along the track. The stage comprises a motive force generator, a rotatable member and a rotary brake. The motive force generator is operable to move the stage along the track. The rotatable member is coupled with the fixed member in a manner that converts motion of the stage along the track into rotation of the rotatable member. The rotary brake is selectively operable to apply a braking torque to the rotatable member. The coupling between the rotatable member and the fixed member converts the braking torque applied to the rotatable member into a braking force applied to the stage.

Abstract: A vacuum divider is positioned between rotor blades of a turbo-molecular pump and a vacuum manifold formed from multiple vacuum chambers. A first coupling aperture passes through the vacuum divider and allows gas to pass from a first of the multiple vacuum chambers to the turbo-molecular pump. A second coupling aperture passes through the vacuum divider and allows gas to pass from a second of the multiple vacuum chambers to the turbo-molecular pump.

Abstract: A chromatography column includes a tube, a fit assembly, a first end fitting and a second end fitting. An annular protrusion extends from an end face of the tube to a protrusion height and circumscribes a chamber in fluid communication with the axial bore. Both the chamber and the bore may be filled with a packing material. The fit assembly includes a deformable ring having a yield strength less than a yield strength of the annular protrusion. The ring contacts the annular protrusion such that the frit assembly provides a chamber boundary that retains the packing material. The first end fitting is securely fastened to the tube such that the ring is axially compressed and deformed around the annular protrusion, the chamber height is less than the protrusion height, and the packing material is compressed.

Abstract: A metrology system is provided comprising a diffraction grating mounted on the object, and an interferometer head operable to direct at least one measurement light beam towards the grating at a non-zero angle of incidence. With a single first separation in the second direction between the object and the interferometer head, respective displacement measurements are made at known displacements of the object. From the displacement measurements are generated respective original calibration values, each pertaining to a respective one of the known displacements. With a second separation in the second direction between the object and the interferometer head, a displacement of the object is measured. The measured displacement is corrected using an offset calibration value derived from at least one of the original calibration values and pertaining to at least one offset displacement, offset from the measured displacement.

Abstract: An apparatus for atomic force microscopy (AFM) comprises a first actuator configured to move a cantilever along an axis; a second actuator configured to move the cantilever along the axis; an amplifier; and a crossover network connected between the amplifier, and the first actuator and the second actuator. The crossover network is adapted to provide a first drive signal to the first actuator over a first frequency range and to provide a second drive signal to the second actuator over a second frequency range.

Abstract: The present invention performs measurement for determining a P/A coefficient and/or determination of the P/A coefficient after measurement of a standard density sample for density calibration in an ICP-MS. Specifically, after measuring signal intensity of each mass number in the standard density sample, the P/A coefficient is determined from the signal intensity for a mass number having the signal intensity within a P/A coefficient calibration range, while for a mass number having the signal intensity above the calibration range, a voltage applied to an ion lens of the ICP-MS is changed so that the signal intensity becomes within the calibration range, to thereby adjust an ion transmission ratio of the ion lens, and then the P/A coefficient is determined from the signal intensity determined within the calibration range.

Abstract: An electrical current measurement system. A sense impedance and a composite amplifier are in electrical communication and together define a trans-impedance circuit that presents a frequency-compensated impedance lower than the sense impedance to an input electrical current to be measured. A sense amplifier in electrical communication with the sense impedance provides an output indicative of a magnitude of the input electrical current. A current bypass circuit may parallel the trans-impedance circuit and bypass the input electrical current around the trans-impedance circuit when the current reaches a predefined magnitude. The system may be combined with another current sensor to form a dual-range current measurement instrument.

Abstract: In order to generate a broadband transfer function of complex characteristics of a linear time-invariant (LTI) system, data characterising properties of the system are acquired. A set of poles in the complex plane are defined to characterize the system, and then an iterative process is performed to: define a set of orthonormal rational basis functions incorporating the defined poles, use the orthonormal rational basis functions to estimate transfer function coefficients, and derive revised values for the complex poles, until a desired level of accuracy of the transfer function coefficients is attained. The revised complex poles are used to determine parameters of the broadband transfer function.

Abstract: A flow cell (200) for a sample separation apparatus (10) for separating components of a sample fluid in a mobile phase, the flow cell (200) being configured for detecting the separated components and comprising a tubing (202) having an inner wall (204) and an outer wall (206), the inner wall (204) defining a lumen (208) for conducting the sample fluid, the tubing (202) further having at one end an end face (210), and a detection unit (212) configured for detecting electromagnetic radiation (214) exiting the end face (210) after propagation of the electromagnetic radiation (214) through the sample fluid in a portion of the lumen (208) and through a portion of the tubing (202) between the inner wall (204) and the outer wall (206).

Abstract: A network element is provided with the capability to perform monitoring and/or measurement functions on the element and the network of which it is a part. The monitoring/measurement functionality is implemented by programmable devices to enable the functionality to be modified and updated without removing the network element from service.

Abstract: A probe assembly for a scanning probe microscope (SPM), a cartridge for a probe assembly for an SPM, and a method of attaching a probe tip to an SPM are described.

Abstract: A process for producing a chromatographic stationary phase for use in reversed-phase chromatography. Chromatographic stationary phases prepared according to the methods of the current invention and liquid chromatography columns, which include the stationary phases, are also provided.

Abstract: An ESD protection circuit has a polysilicon bounded SCR connected between a signal input/output interface contact of the integrated circuit and a power supply connection of the integrated circuit and a biasing circuit. The biasing circuit is connected to the polysilicon bounded SCR to bias the polysilicon bounded SCR to turn on more rapidly during the ESD event. The biasing circuit is formed by at least one polysilicon bounded diode and a first resistance. Other embodiments of the biasing circuit include a resistor/capacitor biasing circuit and a second diode triggering biasing circuit.