Abstract: Embodiments of labeled nucleotide compositions are described. Methods are described in which a sample containing RNA is contacted with an enzyme having an RNA ligation activity in the presence of a labeled nucleotide composition to provide labeled RNA. Methods of performing an array analysis of a labeled RNA sample are also described.

Abstract: The present document relates to a system and method of commingling a low volume of a target solution with an array. For example, a quantity of the target solution and a quantity of an immiscible liquid may be introduced into a cavity having an array on an interior surface. The quantities of target solution and immiscible liquid do not fill the volume. Therefore, a gas is contained within the volume. The cavity is then agitated.

Abstract: A method and apparatus for measuring a duration of an event using two time-varying waveforms, each waveform having characteristics such that the waveforms intersect at an intersecting point. The duration of the event can be determined based on the characteristics and a value of the intersecting point of the waveforms. The characteristics of the waveforms can be the gradient or the initial value of the waveforms.

Abstract: An apparatus adapted for measuring the properties of periodic signals and a method for making such measurements is disclosed. The apparatus includes a LO signal generator, a mixer, a low pass filter and an output device. The LO signal generator generates an LO signal comprising a fundamental frequency ?LO and one or more higher harmonics with arbitrary amplitudes and phases. The mixer receives a periodic input signal having harmonics including a highest harmonic of interest, N, and a fundamental frequency, ?in. The mixer outputs an IF signal that is filtered. The filtered IF signal includes a frequency-compressed signal having M harmonics including a fundamental characterized by a frequency ?c<?in. Each of the harmonics in the frequency-compressed signal corresponds to one of the harmonics in the input signal and has an amplitude related to the amplitude of the corresponding harmonic in the input signal.

Abstract: An electrophoresis gel matrix is provided for conducting proteomics, in particular the steps of separating and/or identifying proteins. The matrix comprises at least one chemical reagent being at least one of a denaturing, buffering, disaggregating, reducing, staining or dissolving reagent, and a volume of dimethylsulfoxide. The use of such a matrix, which is provided to be filled into an electrophoresis capillary being part of a microfluidic device for carrying out proteomics, leads to an enhanced resolution of proteins. The matrix is prepared adding a volume of dimethylsulfoxide ranging from 4% to 15%, preferably from 5% to 10%, most preferably from 6% to 8% with respect to the total volume of chemical reagents being comprised in the matrix. A method is provided for preparation of the matrix for conducting proteomics and a method is conducted to carry out proteomics by the use of this matrix.

Abstract: In one embodiment, a spectral map for performing nonlinear calibration of a signal path is developed by 1) identifying a set of frequency locations for a set of particular output signal spurs that result from applying one-tone and two-tone input signals covering a bandwidth of interest to the signal path; 2) developing, based on the set of frequency locations, a spectral map for predistorting, in the frequency domain, signals that are applied to, or received from, the signal path in the time domain; and 3) saving the spectral map for performing nonlinear calibration of the signal path.

Abstract: A Method and Apparatus for Detecting the Presence and Locations of Radio Controlled Improvised Explosive Devices in Real Time. The system will clandestinely detect the presence and location of RCIED's along roadways in real time. This “RCIED Street Sweeper” system consequently allows its users to remove the explosive devices, pre-detonate them, or simply avoid the location so that the weapons cannot be used against a convoy or other important target. The system has the abilities (disclosed in U.S. patent application Ser. No. 10/829,858) to conduct fast wideband scanning of the RF spectrum looking for ambient RF signals as well as RCIED leakage signals. Furthermore the system has the ability to correlate the received leakage signals with the ambient RF signal environment, in order to verify authenticity. Still further, the system has the ability to continually mark and record the precise map location where each of those RF spectrum measurements emanated, including the relative distances between them.

Abstract: In various embodiments of the invention, novel compositions having a polynucleotide bound to a substrate via a cleavable linker are provided, and methods of cleaving a polynucleotide from a substrate are provided.

Abstract: A signal coupling system interposed between a scanning probe and a measurement instrument provides signal communication between the scanning probe and the measurement instrument. The signal coupling system has a pre-stressed shape when the scanning probe is in a neutral position. The pre-stressed shape is designated to provide a characteristic impedance of the signal coupling system that varies linearly as a function of displacement of the scanning probe from the neutral position when the scanning probe is displaced, relative to the neutral position, over a designated range of displacements.

Abstract: An apparatus for performing a distributed algorithm on a distributed system that comprises a plurality of components coupled together by a communication medium, comprises a user interface for permitting a user to enter a distributed algorithm specification that includes a time scale and tasks the components are to perform at specified times in the time scale; and a processor, coupled to receive the user-entered distributed algorithm specification and coupled to the distributed system on which the distributed algorithm is to be performed. The processor includes (i) a task generator for generating tasks for the respective components to perform according to a predetermined time line, and (ii) a distributor for distributing the tasks to the respective distributed system components.

Abstract: A fluidic device comprising a capillary for conducting a fluid and a pivot arm configured for being pivoted, wherein the pivot arm supports at least a portion of the capillary, and a part of the capillary is coiled to at least partially compensate stress resulting from pivoting of the pivot arm.

Abstract: A timing bridge device is used to gain boundary and transparent clock functionality using conventional network components on those network links that require good timing distribution. This timing path is invisible to the network component. The timing bridge device has an internal time clock and timestamps a received message according to the internal time clock when the message is received by a network device and when the message leaves the network device. The time associated with the message is then adjusted based on a determined transit delay.

Abstract: A method for measuring amplifier gain compression in an OFDM signal includes measuring the signal as a function of time to provide an observed time magnitude, demodulating the OFDM signal to determine an estimate of the ideal signal constellation points, performing an inverse FFT on the estimate of the ideal constellation points to produce an estimated ideal time magnitude, comparing the observed time magnitude to the estimated ideal time magnitude to provide a measure of amplifier gain compression.

Abstract: A whispering gallery mode dielectric resonator includes a conductive enclosure comprising a top, a bottom and walls. The resonator also includes a dielectric element disposed in the enclosure and operative to support a desired resonant mode that is dependent on a shape and dimensions of the dielectric resonator; and a mode selective coupling structure disposed over the enclosure and configured to selectively couple electromagnetic energy of the desired mode and configured not to substantially couple electromagnetic energy of a spurious mode supported in a region between the enclosure and the dielectric element.

Abstract: A method for reducing the effect of jitter in sampled data is presented. The invention is based on the modelling of jitter as a phase modulation that acts on all the frequencies component of the sampled record in correlated manner.

Abstract: A method and apparatus for identifying a point on a rendered signal. The rendered signal comprises display-points that correspond to sampled points. A portion of the sampled-points is displayed. A sampled-point is selected from the portion displayed. The signal is rendered on the display to include the display point corresponding to the sampled-point.

Abstract: A polyphase numerically controlled oscillator is disclosed. An input signal is received at a phase accumulator. The phase accumulator provides a phase to a phase interpolator. The phase interpolator then provides a plurality of output phases. The plurality of output phases are provided to a plurality of phase to amplitude converters. Each of said plurality of phase to amplitude converters process one of said plurality of output phases.

Abstract: A separation device includes a separation chamber having a housing for housing a stationary phase configured for separating compounds of a fluid sample. The separation device also includes a filling port configured for filling the stationary phase through a filling channel into the separation chamber, and a locking piece comprising the filling channel. The locking piece is configured to move the filling channel from a first position, wherein an opening of the filling channel is opening into the separation chamber for filling the stationary phase into the separation chamber, to a second position, wherein the separation chamber is locked against the filling channel. The locking piece is configured to move the opening of the filling channel substantially laterally with respect to the housing.

Abstract: Systems, methods and computer readable storage media are provided for identifying, in a signal of interest, signal segments matching a reference signal segment. A processor coupled to memory is adapted to perform operations including: converting the reference signal segment to a first vector characterized by n pairs of data points, wherein n is an integer greater than zero and each pair of data points comprises a data point having a value along the first axis and a value along a second axis normal to the first axis. Segment of the signal of interest are converted to additional vectors, wherein each of the segments of the signal of interest has a first length in a direction along the first axis and has n pairs of data points. A correlation value is calculated between the reference signal segment and each of the segments of the signal of interest, using the first vector and the additional vectors, respectively.

Abstract: A valve arrangement is disclosed for providing a switchable fluid connection between a fluid delivery system for driving a mobile phase and a stationary phase adapted for separating compounds of a sample fluid comprised in the mobile phase.