Abstract: Systems, tools, methods and computer readable media for visualizing a collection of graphs to provide context and focus. A compressed visualization is formed by compressing all of the graphs in a direction along a compression axis of the visualization. At least one of the compressed graphs may be zoomed to make a visualization of the at least one graph having a greater scale along the second axis than a scale of the compressed graphs. The zoomed graph or graphs may be displayed along with the compressed graphs, wherein the zoomed graph or graphs are displayed in a same order relative to the compressed graphs and each other as occupied prior to the zooming.
Abstract: A plunger for a syringe used to inject gas and liquid chromatography samples has an end portion surrounded by a flexible sleeve. The sleeve forms a seal in the bore of a barrel traversed by the plunger, the bore being in fluid communication with a cannula attached to the end of the barrel. The plunger has an end surface that is exposed and is flush with an annular end surface of the sleeve. The plunger end surface, and not the sleeve, contacts the cannula upon injection and avoids imposing cyclical hoop stresses on the barrel which tend to crack the barrel after a finite number of cycles. In a further embodiment, a thin layer of sleeve material covers the end surface of the plunger. The thin layer avoids inducing significant barrel stress.
Abstract: A method and apparatus for measuring electrical signals measures an electromagnetic wave having an interference component at a center frequency and at multiple times to obtain data points. The positions of the data points on a complex plane are calculated. Chords of a circle on the complex plane, wherein the chords passing between pairs of the data points, and the circle fit to the data points are calculated. The chords are used to determine an approximate center of the circle wherein the position of the approximate center of the circle on the complex plane represents the electromagnetic wave with the interference component removed. An indication of the measured electromagnetic wave having the interference component removed is output from the apparatus.
Abstract: Methods, systems and computer readable media for removing trends in signal intensity values from features on a chemical array. Inputted signal values from features on the array are surface fitted to calculate a surface approximation. The surface approximation is normalized and used to de-trend the signal intensity values from the features.
Type:
Grant
Filed:
September 2, 2008
Date of Patent:
October 26, 2010
Assignee:
Agilent Technologies, Inc.
Inventors:
John Frederick Corson, Jayati Ghosh, Svetlana Shchegrova
Abstract: Hermeticity of microcircuit packages is achieved in one embodiment by recognition that water can penetrate the ceramic structure and thus the ceramic structure is sealed and the edges of the ceramic package are metallically bonded to the electronic package. In one embodiment, a clear ceramic dielectric compound is sprayed on the ceramic and then the package is glazed.
Abstract: A surface plasmon resonance (SPR) spectrometer sensor apparatus for measuring a property of an analyte substance that can be adsorbed on a surface by directing a beam of incident radiation on the apparatus at an incident angle relative thereto, receiving a beam of reflected radiation off the apparatus, and measuring dips in reflected radiation as a function of incident angle or wavelength, the dips being indicative of resonances in the apparatus. The SPR spectrometer comprises a conductive layer having a first side which receives incident radiation, and having a second side opposite to the first side; and a dielectric stack having first and second sides opposite to each other, the first side being in contact with the conductive layer, the second side for receiving an analyte sample to be disposed thereon.
Abstract: A discrete drop dispensing device comprises a substrate comprising an upper surface and a lower surface and orifices extending from the upper surface to the lower surface, adapted to receive a fluid at a flow rate. The discrete drop dispensing device also comprises an oscillator disposed adjacent to the substrate and configured to vibrate the substrate to expel drops having a substantially equal volume of the fluid. The flow rate is substantially identical to a drop dispensing rate. A method and a device for performing liquid chromatography are also described. The method comprises automatically adjusting the drop dispensing rate to a change in the flow rate or a change in a composition of a mobile phase of the fluid.
Abstract: Method and Apparatus to Perform Reactive Jamming While Simultaneously Avoiding Friendly Pseudo-Random Frequency Hopping Communications is disclosed. The system provides an enhancement to surgical reactive jammers that combines near-real-time jamming capability with the additional feature of allowing tactical communications. The jammer includes a synchronization subsystem that synchronizes jammer lockout frequencies with those frequencies being hopped to by units that are members of a friendly communications network. The synchronization subsystem is coordinated with, and therefore tied to the time-synchronized cryptography of the friendly communications net. As a result, the jammer will be aware, on a real-time basis, which frequency the friendly communications network will next be hopping to. The jammer's awareness of these future frequencies will allow those frequencies to be “locked out” of the jammer's transmission band dynamically.
Abstract: An apparatus and method for detecting leading pulse edges of a signal includes a controller, hysteresis threshold comparators and qualification timers. The controller uses the outputs from the timers in order to determine whether or not a transition of the input signal constitutes a leading pulse edge of the input signal.
Abstract: Methods for identifying feature boundary pixels are provided. In general, the subject methods involve evaluating a pixel signal to identify any difference in amplitude between a first part of the signal and a second part of the signal. If the difference is significant, the pixel signal may be indicated as a pixel representing a feature boundary. Also provided are systems and programming for performing the subject methods, and an array scanner containing these systems and programming.
Abstract: A Method and Apparatus for Enhancing the Detection of Weak Emitters provide an enhanced method to eliminate the fake hits of a moving weak signal detection system. The method and apparatus have the abilities stated in the previous U.S. patent application Ser. No. 11/332,801 filed by this author, to do moving detection of weak signals, even in dense urban environments. Secondly, the method and apparatus includes additional antennas and hardware boards, in order to verify authenticity of detected targets. Thirdly, the method and apparatus include appropriate DSP algorithms loaded to program the mission. Fourthly, the method and apparatus are enabled to accurately determine the tangential distance of the target from me vehicles centerline. Finally, the method and apparatus provide the ability to continually discard false targets based upon the information provided by these approaches.
Abstract: The present invention provides novel systems for sequencing nucleic acid molecules using dNTPs that are 3? end labeled with cleavable tags that block further extension and uniquely identify the bases to which they are attached. Removal of the tags liberates the 3? ends of the extension products for further extension. In related embodiments, oligonucleotides containing sequence-related cleavable tags are employed in a ligation reaction to determine the sequence of a particular DNA sample.
Abstract: The invention provides a system apparatus and methods for fragmenting various molecules. In particular, the invention may be employed for fragmenting biomolecules like peptides to determine sequence information. The invention provides a mass spectrometry system for photo-activated collision induced dissociation. The mass spectrometry system or device includes an ion source for producing ions, a photon source adjacent to the ion source for photo-activating ions produced by the ion source, an electrical element adjacent to the photon source for creating an electric field for accelerating ions produced by the ion source and photo-activated by the photon source; wherein ions are produced by the ion source, photo-activated by the photon source and accelerated into a surface to cause dissociation of the activated ions; and a detector downstream from the ion source for detecting the collision induced and dissociated ions.
Type:
Grant
Filed:
August 18, 2006
Date of Patent:
October 19, 2010
Assignee:
Agilent Technologies, Inc.
Inventors:
Steven M. Fischer, Harry F. Prest, Robert Lee, Jr.
Abstract: A pump control for controlling a fluid pump for pumping a fluid, the pump control comprising a pump oil path comprising an oil pump and at least one valve, the oil pump being adapted for pumping pump oil to the fluid pump, the at least one valve being arranged downstream of the oil pump, and a control unit adapted for controlling a pump oil pressure in the fluid pump by switching the at least one valve so that the fluid can be pumped in response to the pump oil pressure.
Abstract: A device for sample analysis includes a microfluidic device for separating analytes of a sample comprising a liquid, the microfluidic device comprising a substrate having a first surface and a second surface opposite the first surface, the substrate defining features that collectively occupy an area of the substrate of about 0.1 to 10 cm2, the features comprising a sample input port located at the first surface; a drying agent input port located at the first surface; an enrichment column; a separation column; switching ports located at the second surface; and fluid-conducting passages extending through the substrate from the switching ports to the sample input port, the drying agent input port, the enrichment column and the separation column. Also provided are methods and systems for separating analytes from a sample.
Type:
Grant
Filed:
January 30, 2008
Date of Patent:
October 12, 2010
Assignee:
Agilent Technologies, Inc.
Inventors:
Hongfeng Yin, Reid Brennen, Kevin Killeen
Abstract: A capacitance measuring apparatus which comprises: a voltage source for applying voltage fluctuation to a device under test; a current source for absorbing the current flowing through the resistance component of the device under test; and an ammeter for measuring the leakage current flowing through the device under test before and after voltage fluctuation and the charging current flowing through the device under test as a result of voltage fluctuation.
Abstract: Aspects of the invention include sample ionizing devices and methods of use thereof. Embodiments of the sample ionizing devices include a microplasma generation source with a plasma generation region, a sample input port for delivering a sample to the plasma generation region, and a gas flow element configured to flow gas through the microplasma generation source independently of the sample input port. The devices and methods of the invention find use in a variety of different applications, including analyte detection applications.
Type:
Grant
Filed:
July 11, 2006
Date of Patent:
October 12, 2010
Assignee:
Agilent Technologies, Inc.
Inventors:
David T. Dutton, Randall S. Urdahl, Arthur Schleifer, Karen L. Seward
Abstract: In a high performance liquid chromatography system, wherein a mobile phase is driven through a stationary phase for separating compounds of a sample fluid comprised in the mobile phase, a flow rate of the mobile phase is controlled in dependence on a variation in a control value in the system.
Abstract: A controller for an instrument includes a control program, an object that interfaces between the control program and the device, and a discovery process. The control program is used by the controller to provide software control of a device within the instrument. The object contains control information about the device so that the control information does not need to be known by the control program. The control information is needed to control the device. The discovery process, upon discovery that the device is within the instrument, obtains the control information from data storage within the instrument and instantiates the object.
Abstract: An instrument including a device, a transducer and a calibration module is disclosed. The device produces a reference time and/or a reference frequency. The transducer converts the reference time and/or the reference frequency to a reference signal. The calibration module adjusts an output signal generated by the instrument and/or a result of a measurement taken by the instrument, based on the reference signal. A system including the instrument and a method of calibrating the instrument are also disclosed.