Patents Assigned to Alcon Laboratories, Inc.
  • Use of pluronic surfactant to enhance the cleaning effect of pancreatin on contact lenses
    Patent number: 5672575
    Abstract: A contact lens cleaning solution containing an enzyme having proteolytic activity and a surfactant, and optionally also a chelating agent and urea, and a method of cleaning contact lenses utilizing this solution are described. The solution and method effectively remove deposits of proteinaceous material, mucins, lipids and calcium located either on or beneath the surface of the lens.
    Type: Grant
    Filed: April 29, 1994
    Date of Patent: September 30, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Rolf Schafer
  • Liquid enzyme compositions containing aromatic acid derivatives
    Patent number: 5672213
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 18, 1995
    Date of Patent: September 30, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Ronald P. Quintana, Bor-Shyue Hong
  • Ophthalmic compositions comprising emedastine and methods for their use
    Patent number: 5668133
    Abstract: Topical ophthalmic compositions comprising 1-(2-ethoxyethyl)-2-(4-methyl-1-homopiperazinyl)-benzimidazole and its ophthalmically acceptable acid addition salts have been found to be useful in treating ocular allergies, especially allergic conjunctivitis, giant papillary conjunctivitis, and vernal conjunctivitis.
    Type: Grant
    Filed: May 22, 1995
    Date of Patent: September 16, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: John M. Yanni, Stella M. Robertson, Shigetoshi Okumura, Hitoshi Tanaka, Tadayuki Saito
  • Cloprostenol and fluprostenol analogues and their use to treat glaucoma and ocular hypertension
    Patent number: 5665773
    Abstract: Disclosed is the use of cloprostenol and fluprostenol analogues for the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic compositions comprising said compounds.
    Type: Grant
    Filed: December 18, 1996
    Date of Patent: September 9, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter G. Klimko, John E. Bishop, Verney L. Sallee, Paul W. Zinke
  • Pharmaceutical compositions and methods of treatment of the corneal following laser irradiation
    Patent number: 5665373
    Abstract: Methods for preventing and treating corneal haze resulting from exposure of the eye to laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators to the eye. Compositions for use in preventing and treating the corneal haze are also disclosed.
    Type: Grant
    Filed: March 16, 1995
    Date of Patent: September 9, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Stella M. Robertson, Herman Melvin Kunkle, Jr.
  • Sulfated polyvinyl alcohol polymers to stabilize pharmaceutical drug compounds
    Patent number: 5662919
    Abstract: Stable formulations of positively charged, hydrolytically unstable drug compounds are obtained by adding a sulfated polyvinyl alcohol copolymer to the formulations.
    Type: Grant
    Filed: November 21, 1994
    Date of Patent: September 2, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Ernesto J. Castillo, Yusuf Ali, Ruma P. Sarkar
  • Polymerizable yellow dyes and their use in ophthalmic lenses
    Patent number: 5662707
    Abstract: Novel polymerizable yellow dyes are disclosed. Additionally, novel and known dyes are used to block or lower the intensity of blue light transmitted through ocular lenses and other windows.
    Type: Grant
    Filed: June 21, 1996
    Date of Patent: September 2, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: David L. Jinkerson
  • Method of varying luminous intensity of light in an illumination system
    Patent number: 5658070
    Abstract: A fiberoptic illumination system having an attenuator with a "multiple wedge" aperture that more uniformly attenuates the light beam striking the fiberoptic without changing the color temperature of the light beam or affecting the exit divergence angle of the light beam. The system includes an optical housing design having orthogonal lights paths that allows two fiberoptics to be illuminated from the same bulb, two bulbs located in primary and back-up positions, respectively, mounted on a rotating carousel and a retinal protection filter that filters out wavelengths of light harmful to the retina.
    Type: Grant
    Filed: October 27, 1994
    Date of Patent: August 19, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: T. Scott Rowe, Eric Marason, David Wilkinson
  • Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
    Patent number: 5653972
    Abstract: Disclosed are storage-stable preserved ophthalmic compositions containing acidic drugs in combination with polymeric quaternary ammonium compounds and boric acid.
    Type: Grant
    Filed: August 21, 1996
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Suketu Dipakbhai Desai, Diane S. Nelms
  • Contact lens cleaning composition containing polyalkylene oxide modified siloxanes
    Patent number: 5654262
    Abstract: Compositions and methods are provided for cleaning and wetting of contact lenses, especially rigid, gas-permeable contact lenses. The compositions comprise low molecular weight polyalkylene oxide modified siloxanes, which are particularly effective in removing lipids from the surface of contact lenses.
    Type: Grant
    Filed: March 14, 1995
    Date of Patent: August 5, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nayan N. Desai, Ronald P. Quintana, Masood A. Chowhan
  • Ethacrynic acid-like compounds and use thereof to treat glaucoma
    Patent number: 5650541
    Abstract: Compounds structurally related to ethacrynic acid are described. The compounds are useful for controlling intraocular pressure. Unlike ethacrynic acid, the compounds of the present invention are capable of effectively penetrating the cornea. Methods of controlling intraocular pressure via topical application of one or more of the compounds to the eye and topical ophthalmic compositions useful in the treatment of glaucoma are also described.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: July 22, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Jesse A. May
  • Cross-linked polyethylene oxide coatings to improve the biocompatibility of implantable medical devices
    Patent number: 5645882
    Abstract: Polyethylene oxide (PEO) coatings providing improved biocompatibility for implantable medical devices are disclosed. The PEO coatings comprise functionalized end-capped PEO which is attached at one end to the medical device. The PEO compounds are then exposed to a high energy source for a time sufficient to cause the PEO compounds to form a cross-linked, insoluble network. These PEO coatings am able to survive ethylene oxide sterilization procedures with minimal loss of protein or cell repulsion ability.
    Type: Grant
    Filed: November 29, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Gerard Llanos
  • Phacoemulsification sleeve
    Patent number: 5645530
    Abstract: A phacoemulsification sleeve having a centering ring isolated within an outer shell. A bellows-like sleeve between the handpiece and the outer shell provides a fluid path for the irrigating fluid.
    Type: Grant
    Filed: August 28, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mikhail Boukhny, Thomas G. Capetan
  • Compounds having both potent calcium antagonist and antioxidant activity and use thereof as cytoprotective agents
    Patent number: 5646149
    Abstract: Compounds having both calcium antagonist and antioxidant activity are disclosed. The compounds are useful in preventing or alleviating damage to tissues at the cellular level. Methods of treatment which employ these properties of the compounds and corresponding pharmaceutical compositions are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, George Barnes, Robert J. Collier, Jr.
  • Thiophene sulfonamides useful as carbonic anhydrase inhibitors
    Patent number: 5646142
    Abstract: New thiophene sulfonamides useful as carbonic anhydrase inhibitors are disclosed. Methods for using the compounds to control IOP are also disclosed.
    Type: Grant
    Filed: July 8, 1994
    Date of Patent: July 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Anura P. Dantanarayana, Thomas R. Dean, Jesse A. May
  • Systemic administration of esters and amides of antioxidants which may be used as antioxidant prodrug therapy for oxidative and inflammatory pathogenesis
    Patent number: 5643943
    Abstract: Methods for treating vascular inflammatory pathologies are disclosed. Particularly, the methods utilize pharmaceutical compositions containing certain compounds having an anti-inflammatory and anti-oxidant moiety covalently linked by an amide or ester bond. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 1, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Daniel A. Gamache, Mark R. Hellberg, Jon C. Nixon, Gustav Graff
  • Topical ophthalmic formulations for treating allergic eye diseases
    Patent number: 5641805
    Abstract: Topical ophthalmic formulations of the invention contain as an active ingredient 11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid or a pharmaceutically acceptable salt thereof. The formulations are useful for treating allergic eye diseases such as allergic conjunctivitis, vernal conjunctivitis, vernal keratoconjunctivitis, and giant papillary conjunctivitis.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 24, 1997
    Assignees: Alcon Laboratories, Inc., Kyowa Hakko Kogyo Co. Ltd.
    Inventors: Eiji Hayakawa, Masashi Nakakura, Stella M. Robertson, John Michael Yanni
  • Surgical console
    Patent number: D380550
    Type: Grant
    Filed: November 14, 1995
    Date of Patent: July 1, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: James R. Dennewill, Russell L. Finlay, Paul R. Hallen, John C. Huculak, John A. Ripley, Richard L. Zaleski, II, David Weston
  • Surgical handpiece holder
    Patent number: D381421
    Type: Grant
    Filed: December 14, 1995
    Date of Patent: July 22, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Peter D. Casica, James Y. Chon
  • Ophthalmic lens case
    Patent number: D382399
    Type: Grant
    Filed: May 30, 1996
    Date of Patent: August 19, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Robert Hambleton, Stephen J. Van Noy, Yi-Ren Woo