Patents Assigned to Alcon Laboratories, Inc.
  • Apparatus and method for cleaning and disinfecting contact lenses
    Patent number: 5637497
    Abstract: A lens storage container having an interior coated with an enzymatic cleaning composition useful for cleaning and disinfecting contact lenses.
    Type: Grant
    Filed: June 28, 1995
    Date of Patent: June 10, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Ralph P. Stone
  • Infusion sleeve
    Patent number: 5634912
    Abstract: An infusion sleeve having a two-piece body. The first piece is conical in shape and is attached to the handpiece by conventional methods. The distal end of the first piece contains a series of annular grooves. The second piece is tubular in shape and contains an annular rim or lip on the proximal end that interlocks within the annular grooves on the first piece.
    Type: Grant
    Filed: February 12, 1996
    Date of Patent: June 3, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: Valentine P. Injev
  • Sustained release comfort formulation for glaucoma therapy
    Patent number: 5635172
    Abstract: Disclosed are nonstinging, sustained release ophthalmic formulations to control intraocular pressure in antiglaucoma therapy comprising a basic active, a cation exchange resin, and, inter alia, an acidic, mucomimetic polymer. Also disclosed are methods of treatment comprising administering such formulations topically to the eye when indicated for control and lowering of intraocular pressure.
    Type: Grant
    Filed: February 27, 1995
    Date of Patent: June 3, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rajni Jani, Robert G. Harris
  • Use of sustained release antibiotic compositions in ophthalmic surgical procedures
    Patent number: 5631004
    Abstract: An improved method of sterilizing the field of surgery prior to an ophthalmic surgical procedure is described. The invention eliminates the need for painful and potentially traumatic injections of antibiotics by utilizing sustained release compositions which allow the antibiotics contained therein to penetrate deeply into the eye, thereby ensuring a sterile field of surgery during intraocular surgical procedures. The compositions may also be utilized to prevent post-surgical infections.
    Type: Grant
    Filed: September 30, 1993
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Gerald D. Cagle, Tai-Lee Ke, Barry A. Schlech, Ole J. Lorenzetti
  • Storage-stable prostaglandin compositions
    Patent number: 5631287
    Abstract: The use of polyethoxylated castor oils in prostaglandin compositions greatly enhances the prostaglandin's chemical stability.
    Type: Grant
    Filed: December 22, 1994
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: L. Wayne Schneider
  • Use of amidoamines in ophthalmic compositions
    Patent number: 5631005
    Abstract: The use of certain amidoamines to disinfect contact lenses and preserve ophthalmic compositions is described. Ophthalmic compositions containing these compounds as disinfecting agents or preservatives are also described. The amidoamines utilized in the present invention have potent antibacterial and antifungal activity, and are chemically compatible with inorganic ions and other materials utilized in ophthalmic compositions.
    Type: Grant
    Filed: February 24, 1995
    Date of Patent: May 20, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Nissanke L. Dassanayake, Ronald L. Schlitzer, Joonsup Park
  • Use of diamines in ophthalmic compositions
    Patent number: 5627214
    Abstract: Certain alkenyl diamines, the use of same for disinfecting and cleaning contact lenses and preserving ophthalmic products, and associated ophthalmic compositions are described.
    Type: Grant
    Filed: February 16, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Rolf Schafer, Ronald L. Schlitzer, Nissanke L. Dassanayake
  • Use of certain 9-haloprostaglandins to treat glaucoma and ocular hypertension
    Patent number: 5627209
    Abstract: 9-Haloprostaglandins are useful in the treatment of glaucoma and ocular hypertension. Also disclosed are ophthalmic, pharmaceutical compositions comprising such prostaglandins.
    Type: Grant
    Filed: October 25, 1995
    Date of Patent: May 6, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Pharmaceutical compositions and methods of treatment of the cornea following laser irradiation
    Patent number: 5624893
    Abstract: Methods for treating the cornea following laser irradiation are disclosed. The methods include administration of compositions of wound healing modulators and pain mediators to the eye. Compositions for use in treating the cornea are also disclosed.
    Type: Grant
    Filed: December 13, 1994
    Date of Patent: April 29, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventor: John M. Yanni
  • Topical ophthalmic carbonic anhydrase inhibitor formulations
    Patent number: 5620970
    Abstract: The present invention is directed to topical ophthalmic formulations of carbonic anhydrase inhibitors and polyethoxylated derivatives of castor oil. Methods for using the formulations for treating and controlling glaucoma and ocular hypertension are also disclosed.
    Type: Grant
    Filed: June 5, 1995
    Date of Patent: April 15, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Wesley W. Han, Thomas R. Dean, Steven H. Gerson, Yusuf Ali, Rajni Jani
  • Thermally-gelling drug delivery vehicles containing cellulose ethers
    Patent number: 5618800
    Abstract: Drug delivery vehicles which reversibly increase in either loss modulus or storage modulus, or both, upon contact with the eye, skin, mucous membrane or body cavity are disclosed. The vehicles contain one or more nonionic substituted cellulose ethers and do not require a charged surfactant or a pH-sensitive polymer for such increase in loss modulus or storage modulus, or both, upon administration. In one embodiment, the vehicles gel upon instillation in the eye.
    Type: Grant
    Filed: August 23, 1995
    Date of Patent: April 8, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bhagwati P. Kabra, John C. Lang
  • Substantially pure apraclonidine
    Patent number: 5612364
    Abstract: Compositions containing, and methods for controlling intraocular pressure with, substantially pure apraclonidine are disclosed.
    Type: Grant
    Filed: November 8, 1995
    Date of Patent: March 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Billie M. York, John M. Yanni, Mark T. DuPriest
  • Esters and amides of non-steroidal anti-inflammatory carboxylic acids which may be used as anti-oxidants, 5-lipoxygenase inhibitors and non-steroidal anti-inflammatory prodrugs
    Patent number: 5607966
    Abstract: Compounds having anti-inflammatory and anti-oxidant activity are disclosed. The compounds are useful in preventing and treating inflammatory disorders through several mechanisms. Methods of treatment employing these properties of the compounds and corresponding pharmaceutical compositions are disclosed.
    Type: Grant
    Filed: December 23, 1994
    Date of Patent: March 4, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Mark R. Hellberg, Gustav Graff
  • Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
    Patent number: 5605922
    Abstract: Combinations of at least one clonidine derivative and at least one prostaglandin are used to treat glaucoma and ocular hypertension without some of the side effects typically associated with topical administration of prostaglandins.
    Type: Grant
    Filed: December 12, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Verney L. Sallee
  • Methods of using liquid enzyme compositions containing mixed polyols
    Patent number: 5605661
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: August 18, 1995
    Date of Patent: February 25, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Bahram Asgharian, Bor-Shyue Hong
  • Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
    Patent number: 5604190
    Abstract: Compositions containing a stable, liquid, ophthalmically acceptable enzyme and methods involving the combined use of these compositions with a polymeric antimicrobial agent, and complexing agent are disclosed for the simultaneous cleaning and disinfecting of contact lens. Methods for a daily use regimen are also disclosed.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Masood A. Chowhan, Ronald P. Quintana, Bahram Asgharian, Bor-Shyue Hong, Thierry Bilbault, Ruth A. Rosenthal
  • Method for reducing tackiness of soft acrylic polymers
    Patent number: 5603774
    Abstract: The tackiness associated with certain soft acrylic polymers can be reduced by plasma treatment of the polymer surface. This is particularly useful with regard to intraocular lenses (IOLs), especially foldable IOLs, which are made from such soft acrylic polymers.
    Type: Grant
    Filed: December 11, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Albert R. LeBoeuf, George Green, Barbara A. Piper
  • Intraocular irrigating solution containing a polyamine antagonist
    Patent number: 5604244
    Abstract: Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more polyamine antagonists, and are useful for preventing or treating excitotoxicity associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Louis DeSantis, Jr., Michael A. Kapin
  • Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
    Patent number: 5603929
    Abstract: Disclosed are storage-stable preserved ophthalmic compositions containing acidic drugs in combination with polymeric quaternary ammonium compounds and boric acid.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: February 18, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Suketu D. Desai, Diane S. Nelms
  • Double redox system for disinfecting contact lenses
    Patent number: 5591397
    Abstract: An improved method for rapid disinfection of contact lenses in a convenient and reliable manner is disclosed in which a series of oxidation-reduction reactions are employed. Specifically, dichloroisocyanurate and potassium iodide react to form iodine species for disinfecting the contact lens. An amount of ascorbate is then added to neutralize the iodine species.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 7, 1997
    Assignee: Alcon Laboratories, Inc.
    Inventors: Ronald L. Schlitzer, N. L. Dassanayake, Rajkumar P. Bhatia