Patents Assigned to Ares Trading S.A.
  • Production of Recombinant IL-18 Binding Protein
    Publication number: 20100137195
    Abstract: The invention relates to a process for the production of IL-18 binding protein (IL-18BP), and to a composition comprising IL-18BP characterized by a specific glycosylation pattern.
    Type: Application
    Filed: February 15, 2010
    Publication date: June 3, 2010
    Applicant: ARES TRADING S.A.
    Inventors: URS WEBER, Thierry Ziegler
  • Serum-free cell culture medium for mammalian cells
    Patent number: 7709229
    Abstract: This invention relates to a process for the manufacturing of a protein in mammalian cells cultured in a serum-free medium.
    Type: Grant
    Filed: October 28, 2005
    Date of Patent: May 4, 2010
    Assignee: Ares Trading S.A.
    Inventors: José Casatorres Hernandez, Carlos Martin Piera
  • Lipid microparticles by cryogenic micronization
    Patent number: 7704525
    Abstract: This invention relates to Lipid Microparticles consisting of lipids enriched in amphiphilic components, which promote the incorporation of peptides and/or protein, process for obtaining them as well as use thereof. A cryogenic micronization manufacturing process for their preparation is also disclosed.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: April 27, 2010
    Assignee: Ares Trading S.A.
    Inventors: Maria Dorly Del Curto, Daniela Chicco, Pierandrea Esposito
  • Hand-held electronically controlled injection device for injecting liquid medications
    Patent number: 7704231
    Abstract: A hand-held, electronically controlled injection device (1) for injecting preset doses of liquid medications, having a housing (2) for receiving a cartridge (4) containing the liquid medication and having a contact surface (16) for contacting a patient's skin; and actuator elements (41) for moving the cartridge (4) within the housing (2) to and from the contact surface (16).
    Type: Grant
    Filed: February 17, 2005
    Date of Patent: April 27, 2010
    Assignee: Ares Trading S.A.
    Inventors: Vincent Pongpairochana, Timothy John MacLean, Robert Prasser, Gerhard Lauchard, Werner Wurmbauer, Gerhard Kogler
  • Isolated INSP 163 protein
    Patent number: 7700724
    Abstract: This invention relates to the novel protein, termed INSP163, herein identified as a secreted protein containing a jelly-roll fold, in particular, as a member of the TNF (tumor necrosis factor)-like family of cytokines, specifically as a C1q-like protein and to the use of this protein and nucleic acid sequence from the encoding gene in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: October 27, 2004
    Date of Patent: April 20, 2010
    Assignee: Ares Trading S.A.
    Inventors: Stephen Noel Fitzgerald, Richard Joseph Fagan, Christine Power, Melanie Yorke, Jadwiga Bienkowska
  • Production of recombinant IL-18 binding protein
    Patent number: 7691611
    Abstract: The invention relates to a process for the production of IL-18 binding protein (IL-18BP), and to a composition comprising IL-18BP characterized by a specific glycosylation pattern.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: April 6, 2010
    Assignee: Ares Trading S.A.
    Inventors: Urs Weber, Thierry Ziegler
  • Cystine-Knot Fold Cytokine
    Publication number: 20100048467
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: January 12, 2006
    Publication date: February 25, 2010
    Applicant: ARES TRADING S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson, Yan Lavrovsky
  • Liquid growth hormone formulation and method of use
    Patent number: 7662393
    Abstract: The invention relates to a liquid formulation comprising a growth hormone or a substance, which stimulates release or potentiates the activity of endogenous hGH; a polyethylene-polypropylene glycol; a citrate/phosphate buffer, an alkali metal salt and an alkaline earth metal salt or a pseudo alkaline earth metal salt, and to a process of preparation thereof.
    Type: Grant
    Filed: March 30, 2005
    Date of Patent: February 16, 2010
    Assignee: Ares Trading S.A.
    Inventors: Tudor Arvinte, Karnine Luet Kleiber
  • Use of IL-18 inhibitors for treating head injuries
    Patent number: 7655616
    Abstract: The invention relates to the use of inhibitors of IL-18 in the preparation of a medicament for treatment and/or prevention of central nervous system injury, in particular of traumatic head injury.
    Type: Grant
    Filed: May 23, 2002
    Date of Patent: February 2, 2010
    Assignee: Ares Trading S.A.
    Inventor: Esther Shohami
  • TREATMENT OF CARTILAGE DISORDERS WITH FGF-18
    Publication number: 20100016223
    Abstract: This invention concerns the treatment of cartilage disorder and osteoarthritis in particular. More specifically, it relates to the use of FGF-18 in treatment regimens and for the manufacture of a medicament for the treatment of patients having a cartilage disorder such as osteoarthritis, such as for example knee osteoarthritis or secondary hip osteoarthritis. Specifically provided is a preferred treatment scheme comprising once weekly administration of an FGF-18 compound per treatment cycle.
    Type: Application
    Filed: August 24, 2007
    Publication date: January 21, 2010
    Applicant: Ares Trading S.A.
    Inventors: Alberto Gimona, Christoph H. Ladel, Elmar Vom Baur
  • Oral Pharmaceutical Composition of Anilinopyrimidine, Preparation and Use Thereof
    Publication number: 20090324711
    Abstract: An oral pharmaceutical composition comprising a capsule dosage form containing a liquid fill composition including an anilinopyrimidine derivative of Formula (I) and a pharmaceutically acceptable excipient selected from the group consisting of polyethylene glycol, a glyceryl ester of capric acid or a mixture thereof. The liquid fill composition is formulated in a hard gelatin capsules and can be used for the preparation of a medicament for the treatment of cancer in particular AML.
    Type: Application
    Filed: July 5, 2007
    Publication date: December 31, 2009
    Applicant: Ares Trading S.A.
    Inventors: Santa Fabiano, Mario Maio
  • ANALYTICAL METHOD FOR ANALYZING C-TERMINUS TRUNCATION
    Publication number: 20090311732
    Abstract: This invention relates to analytical methods for quantification of truncation at the C-terminus of an Fc-containing protein.
    Type: Application
    Filed: December 20, 2007
    Publication date: December 17, 2009
    Applicant: Ares Trading S.A.
    Inventors: Mara Rossi, Irene Cecchini
  • Cytokine antagonist molecules
    Patent number: 7622555
    Abstract: This invention relates to a novel protein (INSP052), herein identified as an immunoglobulin domain-containing cell surface recognition molecule and to the use of this proteins and nucleic acid sequences from the encoding gene in the diagnosis, prevention and treatment of disease. The invention also relates to the identification of the extracellular domain of INSP052.
    Type: Grant
    Filed: November 12, 2003
    Date of Patent: November 24, 2009
    Assignee: Ares Trading S.A.
    Inventors: Andrew Robert Davids, Richard Joseph Fagan, Christopher Benjamin Phelps, Christine Power, Yolande Chvatchko, Ursula Boschert
  • INTERLEUKIN-18 MUTANTS, THEIR PRODUCTION AND USE
    Publication number: 20090286855
    Abstract: The invention provides mutants of IL-18 with lower affinity to IL-18BP than the wild type IL-18 molecule.
    Type: Application
    Filed: March 16, 2009
    Publication date: November 19, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Charles A. Dinarello, Soo-Hyun Kim
  • Cystine-knot fold protein
    Patent number: 7619065
    Abstract: This invention relates to a novel protein (INSP002), herein identified as a secreted protein that is a member of the Dan family of the cystine-knot fold cytokine superfamily and to the use of this protein and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Grant
    Filed: June 21, 2004
    Date of Patent: November 17, 2009
    Assignee: Ares Trading S.A.
    Inventors: Mark Douglas Davies, Christopher Benjamin Phelps, Richard Joseph Fagan, Christine Power, Melanie Yorke, Mark Ibberson
  • INJECTION DEVICE WITH A CAPACITIVE PROXIMITY SENSOR
    Publication number: 20090216182
    Abstract: An injection device for injecting medication to a patient, comprising a surface (5) having a through hole (3) for passage of a needle, is characterised by further comprising a capacitive proximity sensor (12, 13, 30) for detecting proximity or contact of human skin to/with said surface (5).
    Type: Application
    Filed: January 30, 2007
    Publication date: August 27, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Gerhard Lauchard, Martin Reindl, Claudia-Carolin Guggenberger
  • Cys-Rich, Cell Surface Glycoproteins
    Publication number: 20090215672
    Abstract: This invention relates to novel proteins, termed INSP206 and INSP208 herein identified as Cys-rich, cell surface glycoproteins, and to the use of these proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of disease.
    Type: Application
    Filed: December 7, 2006
    Publication date: August 27, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Christine Power, David Michalovich, Richard James Mitter
  • TGR3-Like Protein Receptor
    Publication number: 20090214548
    Abstract: There are provided proteins containing a domain corresponding to the C-terminal half of a ZP domain similar to that identified in TGF-beta Receptor III and the use of the proteins and nucleic acid sequences from the encoding genes in the diagnosis, prevention and treatment of diseases. In particular, the present invention relates to the use of the disclosed proteins for modulating the activity of proteins belonging to the TGF-beta superfamily.
    Type: Application
    Filed: December 8, 2005
    Publication date: August 27, 2009
    Applicant: Ares Trading S.A.
    Inventors: David Michalovich, Richard James Mitter, Richard Joseph Fagan, Christine Power
  • METHOD FOR PURIFYING FSH OR A FSH MUTANT
    Publication number: 20090209454
    Abstract: The invention relates to a method for purifying a glycoprotein, preferably FSH or a FSH mutant comprising the steps of subjecting a liquid containing said FSH or a FSH mutant to: (1) a dye affinity chromatography; (2) a weak anion exchange chromatography; (3) a hydrophobic interaction chromatography; and (4) a strong anion exchange chromatography; which may be carried out in any order.
    Type: Application
    Filed: December 6, 2006
    Publication date: August 20, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Thierry Ziegler, Mara Rossi, Antonello Datola, Sabrina Fiumi
  • Device for Overturning Containers
    Publication number: 20090196726
    Abstract: The invention relates to a device (1) for overturning containers (2), particularly roller bottles intended for cell cultures, characterized in that it comprises a rotation actuator (3) associated by means of a transmission shaft (13) to a reducer (4) and a dynamic brake (5), a support (17) and rods (7) gripping the container (2), said support (17) being joined to the rotation actuator (3) by means of a shifter (16) of the transmission shaft (13) of the mentioned rotation actuator (3), the rotation actuator (3) being actuated by means of a pneumatic foot pedal (18), and the mentioned rotation actuator (3) in turn being associated to a timer (19) indicating the end of the overturning time of the container (2).
    Type: Application
    Filed: August 21, 2007
    Publication date: August 6, 2009
    Applicant: ARES TRADING S.A.
    Inventors: Antonio Campos Del Olmo, Mario Ugolini