Abstract: Therapeutic methods of treating chronic lymphocytic leukemia (CLL) and small lymphocytic leukemia (SLL) are described. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating subtypes of CLL and SLL using a BTK inhibitor, including subtypes of CLL in patients sensitive to thrombosis and subtypes of CLL that increase monocytes and NK cells in peripheral blood after treatment with a BTK inhibitor. In certain embodiments, the invention includes therapeutic methods of treating CLL and SLL using a combination of a BTK inhibitor and an anti-CD20 antibody.

Abstract: The invention relates to a system for adjusting at least two sets of shutoff elements of an air intake of a motor compartment of a motor vehicle. The system comprises at least two adjustment units. Each adjustment unit comprises a drive unit comprising an electric motor and a drive train for adjusting a set of shutoff elements. One adjustment unit is a primary adjustment unit and a further adjustment unit is a secondary adjustment unit. The primary adjustment unit is arranged for primary connection with a central control unit, such as an onboard computer of a motor vehicle. Also, the primary adjustment unit is arranged for secondary connection with the secondary adjustment unit. In the system the secondary adjustment unit has no direct connection with the central control unit.

Abstract: In a printer, a print head carriage assembly includes a carriage arranged to move in a main scanning direction relative to a recording medium; a plurality of print heads mounted on the carriage and arranged to apply a curable marking material onto the recording medium; and a number of curing devices mounted on the carriage and disposed in positions relative to the print heads such that each print head is associated with at least one of the curing devices. The at least one of the curing devices is disposed to follow its associated print head in a distance in the main scanning direction so as to cure the ink that has been applied with that print head. The print heads are arranged in at least two rows which extend in the main scanning direction and are staggered in a sub-scanning direction normal to the main scanning direction, and the print heads are grouped such that each print head in each row has, in each other row, a counterpart print head which belongs to the same group.

Abstract: The present invention relates to a brine injection system with a plurality of needles, which are inserted into a product and through which brine is injected into the product, wherein brine which does not end up in the product is collected and recycled and wherein during recycling, the brine flows through a filter.

Abstract: The present invention relates to powdery mildew resistance providing genes of the Cucumis family, and especially Cucumis sativus, wherein said resistance is provided by impairment of the present genes. Further, the present invention relates plants comprising the present impaired resistance conferring genes and seeds, embryos or other propagation material thereof. Especially, the present invention relates to powdery mildew resistance conferring genes, wherein the amino acid sequence encoded by said resistance conferring gene is selected from the group consisting of SEQ ID NO: 2, SEQ ID NO: 4, SEQ ID NO: 6, SEQ ID NO: 8, SEQ ID NO: 10, SEQ ID NO: 12, SEQ ID NO: 14, SEQ ID NO: 16, SEQ ID NO: 18, SEQ ID NO: 20, and SEQ ID NO: 22, and amino acid sequences with more than 70% identity, preferably more than 80% identity, more preferably more than 90% identity, and most preferably more than 95% identity.

Abstract: An approach is provided for generating a minimum overlapping alternative path. The approach involves receiving a constraint parameter for traversing a path between a first location and a second location. The approach also involves determining a critical portion of the path that is to be traveled to satisfy the constraint parameter, and designating a remaining portion of the path that is not the critical portion as a non-critical portion. The approach further involves calculating one or more candidate minimum overlapping alternative paths for the non-critical portion of the path. The approach further involves generating the minimum overlapping alternative path between the first location and the second location by combining the critical portion of the path with a selected one of the one or more candidate minimum overlapping alternative paths that satisfies the constraint parameter.

Abstract: A system for preparing a drink by mixing a drink extract with water, wherein the system comprises an extract container for holding a predefined amount of drink extract and a mixing device, wherein the extract container is an independent unit, closed from all sides and the mixing device comprises a water transport pipe that at one end is connectable to a water feed, and a hollow space that is arranged for receiving the extract container, wherein the hollow space at a bottom side is fluidly connected with the water transport pipe; wherein the water transport pipe at a location of the connection with the hollow space comprises a constriction for creation during operation of an underpressure at that location.

Abstract: A new non-HIV vaccine antigen from Mycoplasma sp. permease capable of inducing a mucosal neutralizing protective antibody response against HIV infection, a neutralizing antibody directed to said antigen, and a method for the identification of new antigens from the mucosal microbiota for the development of vaccines against pathogens.

Abstract: A memory controller includes a clock delay generator, a set of flip-flops, and a control circuit, and is connected to a processor and a memory. The clock delay generator receives a clock signal from the processor, delays the clock signal by a set of delay time intervals, and generates a set of delayed clock signals. The flip-flops receive a test pattern and read data from the memory, sample the test pattern and the read data based on the delayed clock signals, and generate a set of sampled test patterns and a set of sampled read data. The control circuit identifies a sampled test pattern that is equal to the test pattern and the corresponding delayed clock signal as a read clock signal, and outputs the sampled read data that corresponds to the (delayed) read clock signal.

Abstract: In a lithographic process, product units such as semiconductor wafers are subjected to lithographic patterning operations and chemical and physical processing operations. Alignment data or other measurements are made at stages during the performance of the process to obtain object data representing positional deviation or other parameters measured at points spatially distributed across each unit. This object data is used to obtain diagnostic information by performing a multivariate analysis to decompose a set of vectors representing the units in said multidimensional space into one or more component vectors. Diagnostic information about the industrial process is extracted using the component vectors. The performance of the industrial process for subsequent product units can be controlled based on the extracted diagnostic information.

Abstract: The invention relates to a paper guide rope braided from a plurality of textile subunits, wherein each subunit contains a plurality of twisted yarns made from multifilament yarn. The rope according to the invention is characterized in that the titre of at least part of the twisted yarns, preferably of all the twisted yarns, is in each case at most 5000 dtex, and that the twist rate of at least part of the twisted yarns, preferably of all the twisted yarns, is in each case at least 150 T/m.

Abstract: A system for performing an operation in a wellbore comprises a tool (4) configured for deployment within the wellbore on an insulated slickline (6), and a winch (26) for hauling in and/or paying out the slickline. The system further comprises a winch controller (34) which is configured to receive information transmitted electrically from the tool along the slickline and to control the winch according to the received information. The tool may comprise a downhole tractor. The tool may comprise an electrical generator tool or a tool for performing a mechanical operation within the wellbore.

Abstract: Herein is described an electrophotographic printing process in which a liquid electrophotographic ink image and a dry electrophotographic toner image may be printed on a print substrate.

Abstract: Thermal atomic layer etching processes are disclosed. In some embodiments, the methods comprise at least one etch cycle in which the substrate is alternately and sequentially exposed to a first vapor phase halide reactant and a second vapor halide reactant. In some embodiments, the first reactant may comprise an organic halide compound. During the thermal ALE cycle, the substrate is not contacted with a plasma reactant.

Abstract: The present invention relates to a process for making a thermoplastic composition, comprising the steps of: a) melt mixing a first thermoplastic polymer and a paper product comprising a mixture of cellulose fibers and a second thermoplastic polymer.

Abstract: The invention relates to a method for operating a node in a network comprising a resource restricted device, the method comprising the steps of (a) placing an ACK message in a buffer of the node, if said buffer does not contain a buffered message to be transmitted to the resource restricted device; (b) after step (a), detecting a received message transmitted by the resource restricted device; (c) transmitting the ACK message or the buffered message to the resource restricted device after detection of the received message; the method further comprising repeating steps (a) to (c) after the ACK message or the buffered message has been transmitted, so that the buffer always contains a message ready to be sent.

Abstract: A new and distinct cultivar of Hydrangea plant named ‘H217905’, characterized by its upright and rounded plant habit; vigorous growth habit and rapid growth rate; freely branching habit with strong, thick and sturdy stems; early, freely and uniformly flowering habit; mophead-type inflorescences with numerous intense red purple-colored sterile flowers; and good postproduction longevity.