Abstract: The invention provides methods for large-scale adenovirus purification from high cell density suspensions, using host cell DNA precipitation followed by a clarification step.
Abstract: A robotic end-effector for high-speed precision alignment and assembly of of a spacer ring onto a motor-hub assembly has a holding device operable for temporarily holding the spacer ring. The spacer ring is to be aligned and assembled to the motor-hub assembly. The robotic end-effector has a course alignment device operable for locating the holding device with respect to a locating feature that is coupled with the motor-hub assembly. The robotic end-effector has a retractor operable for disengaging the course alignment device from the locating feature. The robotic end-effector has a moveable base whereby lateral compliance is provided for the holding device, enabling motion of the spacer ring with respect to the motor-hub assembly, thereby enabling fine alignment of the spacer ring with the motor-hub assembly when the spacer ring touches the motor-hub assembly.
Type:
Grant
Filed:
November 25, 2008
Date of Patent:
June 11, 2013
Assignee:
HGST Netherlands B.V.
Inventors:
Nagappan Chandrasekaran, Ching Keat Tay, Qihong Wang
Abstract: Aspects of the invention relate to a computer-implemented method of controlling a computer application program in a computer system configured for electronically communication with a client. The computer system is configured to have access to a first request set of one or more allowable requests corresponding to a first application state of the computer application program. The computer application program may run on the computer system or on one or more other computer systems. A client request is received at the computer system for the computer application program. The computer application program is in the first application state in relation to said client (using e.g. the client connection). The client request is analysed to determine if the client request matches one of the allowable requests corresponding to the first application state of the computer application program.
Type:
Grant
Filed:
January 17, 2008
Date of Patent:
June 11, 2013
Assignee:
Scipioo Holding B.V.
Inventors:
Dirk Leonard Benschop, Henderik Reinout Benschop
Abstract: The device pertains to a carriage which may be separate or integrated with a mobile, powered loading vehicle to load or unload railroad track materials to or from a gondola and a method thereof.
Abstract: Method, device and system for generating a light control parameter for controlling light (20), e.g. ambient light, in response to an audio signal (A). The audio signal (A) is analyzed in order to extract a temporal evolution of semantic content of the audio signal (A). A light control parameter is then generated according to the temporal evolution of semantic content of the audio signal (A), either on-line or off-line. This enables generating light that is perceptually aligned with the audio signal, e.g. music. In a preferred embodiment spatial properties of the audio signal (A) are extracted, and separate light control parameters are generated for controlling light sources spatially positioned according to the spatial properties of the audio signal, e.g. for stereo or surround sound systems where light sources are positioned near each loudspeaker. Such embodiment enables spatial correspondence between light and audio.
Type:
Grant
Filed:
October 25, 2007
Date of Patent:
June 11, 2013
Assignee:
TP Vision Holding B.V.
Inventors:
Martin Franciscus McKinney, Janto Skowronek, Dragan Sekulovski, Bram Kater
Abstract: A method for processing a carcass part of slaughtered poultry includes making a preliminary incision on both sides of the sternum, the preliminary incision leaving the part of the membrane that is present between the inner fillet and the outer fillet intact, scraping loose the meat that lies against the sternum on either side using a first scraper, scraping at least a part of the meat of the inner fillet loose from the rib cage using a second scraper, cutting through the membrane connection between the inner fillet and the rib cage, and removing the outer fillet and the inner fillet from the bone parts of the carcass part, in which the connection between the inner fillet and the outer fillet remains intact.
Type:
Grant
Filed:
April 30, 2012
Date of Patent:
June 11, 2013
Assignee:
Stork PMT B.V.
Inventors:
Petrus Christianus Hendrikus Janssen, Gerardus Johannes Catharina Van Bussel, Adrianus Josephes Van Den Nieuwelaar
Abstract: A grinding apparatus for dispensing a dose of ground frozen material starting from a frozen block includes a grinding unit for grinding the frozen block in order to provide an amount of ground frozen material and a feeding unit for feeding the frozen block to the grinding unit. In particular, the feeding unit includes a feeding member that is adapted for moving frozen block for a desired predetermined grinding stroke against grinding unit such that a grinding length of block is ground. A grinding unit provides at least one grater and one motor for causing the grater to rotate. In order to obtain a desired weight of the dose, a volume of frozen material is calculated that corresponds to said weight, since the density of the frozen material is known.
Type:
Grant
Filed:
April 2, 2012
Date of Patent:
June 11, 2013
Assignees:
Starstatus Trading Internacional LDA, Fast & Fluid Management, B.V.
Inventors:
Jan Post, Goran Aleksijovski, Wouter Dijkstra, Cristian Bormetti, Marco Bianchi, Bob Honsbeek
Abstract: A lithographic apparatus includes a projection system configured to project a patterned radiation beam onto a target portion of a substrate. The apparatus also includes a barrier member, surrounding a space between the projection system and, in use, the substrate, to define in part with the projection system a reservoir for liquid. A radially outer surface of the barrier member facing a portion of projection system and a radially outer surface of the portion of the projection system facing the barrier member each have a liquidphobic outer surface. The liquidphobic outer surface of the barrier member and/or the liquidphobic outer surface of the portion of the projection system has an inner edge that defines in part the reservoir.
Type:
Grant
Filed:
August 1, 2008
Date of Patent:
June 11, 2013
Assignee:
ASML Netherlands B.V.
Inventors:
Marcel Beckers, Marcus Adrianus Van De Kerkhof, Siebe Landheer, Wouterus Johannes Petrus Maria Maas, Jeroen Peter Johannes Bruijstens, Ivo Adam Johannes Thomas, Franciscus Johannes Joseph Janssen, Bartholomeus Mathias Van Oerle
Abstract: A laser device includes a seed laser, an amplifier, a detector, and an optical element arranged to direct radiation emitted by the seed laser towards a plasma generation site. The optical element is arranged to direct towards the detector amplified spontaneous emission radiation which has been emitted by the seed laser and has been reflected from a droplet of fuel material. The detector is arranged to trigger generation of a laser radiation pulse by the seed laser when the reflected amplified spontaneous emission radiation is detected.
Type:
Grant
Filed:
January 7, 2010
Date of Patent:
June 11, 2013
Assignee:
ASML Netherlands B.V.
Inventors:
Erik Roelof Loopstra, Gerardus Hubertus Petrus Maria Swinkels, Erik Petrus Buurman
Abstract: A polycarbonate containing composition comprising a peak melt viscosity of at least 8,000 poise when measured using a parallel plate melt rheology test at a heating rate of 10° C./min at a temperature of between about 350° C. to about 450° C., and wherein a molded article of the composition has a UL 94 VO rating at a thickness of 1.0 mm, 1.5 mm, 2.0 mm, or between 1.0 mm and 2.0 mm is disclosed.
Abstract: A hoisting crane with a substantially hollow vertical column with a foot which is or can be fixed to a support, and with a top, an annular bearing structure, which extends around the vertical column and guides and carries a jib connection member, so that the jib connection member can rotate around the column, a jib connected to the jib connection member, the jib connection member forming a substantially horizontal pivot axis so that the jib can be pivoted up and down, a column top cable guide having a topping cable and hoisting cable pulley assembly, a topping winch and an associated topping cable for pivoting the jib up and down, a hoisting winch and an associated hoisting cable for hoisting a load; wherein the column top cable guide is mounted via an associated rotary bearing structure at the top of the column.
Type:
Grant
Filed:
February 15, 2008
Date of Patent:
June 11, 2013
Assignee:
ITREC B.V.
Inventors:
Joop Roodenburg, Diederick Bernardus Wijning, Terence Willem August Vehmeijer, Robert Frodo Van Kuilenburg
Abstract: In a single or multiple stage lithography apparatus, a table provides a confining surface to a liquid supply system during, for example, substrate table exchange and/or substrate loading and unloading. In an embodiment, the table has a sensor to make a measurement of the projection beam during, for example, substrate table exchange and/or substrate loading and unloading.
Abstract: According to an example embodiment of the present invention, a method is implemented for transmitting data between a Media Access Control Layer (MAC) (100) and a Physical Layer (PHY) (150) using an internal data bus for transmitting a set of internal symbols between the MAC (100) and PHY (150). A subset of internal symbols does not have a corresponding PHY symbol. An external data bus carries data symbols. An external interface (102, 118) provides command information on one or more dedicated command lines and provides the data symbols. An encoder (108, 110) encodes the provided command information into one or more of the subset of internal symbols. An internal interface (106, 107, 109, 111) transmits the one or more of the subset of internal symbols and the data symbols between the MAC (100) and PHY (150) using the internal data bus.
Abstract: An immersion lithographic apparatus comprising a surface which is curved such that a surface-tension drainage force acts in a direction on a film of immersion liquid on the surface.
Type:
Grant
Filed:
June 18, 2010
Date of Patent:
June 11, 2013
Assignee:
ASML Netherlands B.V.
Inventors:
Johannes Henricus Wilhelmus Jacobs, Hans Jansen, Jeroen Peter Johannes Bruijstens, Ivo Adam Johannes Thomas, Gerardus Adrianus Antonius Maria Kusters, Marcio Alexandre Cano Miranda, Gheorghe Tanasa
Abstract: A process for the preparation of 5-substituted 4-amino-2-methylpyrimidines of the formula (I) wherein R is CONH2 or CN, and of acid addition salts thereof, characterized in that a compound of formula H2N CH?C(R)CN (II) is reacted with acetimidic acid methyl ester or an acid addition salt thereof and that, if desired, a compound of formula (I) is transferred into an acid addition salt, and the transformation of a compound of formula (II) wherein R is CONH2 into a compound of formula (II) wherein R is CN by treatment with POCI3.
Abstract: The invention relates to a process for the preparation of deodorized and stabilized food-grade marine oils by submitting marine oils to a counter-current steam distillation (CCSD) in a thin film column containing a structured packing and, if desired, adding antioxidant(s), to the food-grade marine oils thus obtained and to their uses in the food/feed, cosmetic and/or pharmaceutical industry.
Type:
Grant
Filed:
May 9, 2008
Date of Patent:
June 11, 2013
Assignee:
DSM IP Assets B.V.
Inventors:
Andreas Keller, Ingo Koschinski, Albert Lustenberger, Neil MacFarlane, Thomas Meierhans
Abstract: The invention relates to driving means for displacing two elongate members, the driving means comprising: a first set of at least a row of primary rollers and a row of secondary rollers; a second set of at least a row of primary rollers and a row of secondary rollers; wherein the first set is connected to a first member and the second set is connected to a second member; and wherein a belt serpentines between the primary rollers of the first set and the primary rollers of the second set along the length of the members and serpentines back between the secondary rollers of the first set and the secondary rollers of the second set.
Abstract: The present invention relates to sulphur containing pyrazole derivatives, and their S-oxidized active metabolites, as selective cannabinoid CB1 receptor antagonists having a high CB1/CB2 receptor subtype selectivity, to methods for the preparation of these compounds, to novel intermediates useful for the synthesis of these pyrazole derivatives, to pharmaceutical compositions comprising one or more of these pyrazole derivatives as active ingredients, as well as to the use of these pharmaceutical compositions for the treatment of psychiatric and neurological disorders. The compounds have the general formula (I) wherein the symbols have the meanings given in the specification.
Type:
Grant
Filed:
July 27, 2010
Date of Patent:
June 11, 2013
Assignee:
Solvay Pharmaceuticals B.V.
Inventors:
Josephus H. M. Lange, Cornelis G. Kruse, Bernard J. Vliet Van